Methods In (Bio)Medical Image Analysis - Spring 2022

16-725 (CMU RI) : BioE 2630 (Pitt)

(Frequently also crosslisted as 18-791, CMU ECE : 42-735, CMU BME)

John Galeotti
Meets students after Tuesday's class
Noah Schweitzer
By email or appointment


Course capacity has been increased.  Everyone should now be able to enroll. 

Meeting over Zoom (email for private link)

Classroom (when used):  PH A20
(at Carnegie Mellon University, see campus map)

Class begins Tuesday, Jan. 18th!

Lecture Times and Locations

We comply with both the U. Pitt. and CMU calendars. Lectures are Tuesday and Thursday from 3:05-4:25 PM, in PH A20 or on zoom, Carnegie Mellon University.

Class-discussion  Piazza Page

Shadow Program Times, Locations, & Details  SUSPENDED FOR REST OF SEMESTER

Shadow Program:  6 radiology sessions and 0-2 (TBD) pathology sessions, 8:30-9:30 AM weekday mornings (and possibly other times optional for shadowing pathology).

directions, and required UPMC confidentiality agreement. Reports should be emailed to your TA and Galeotti.

Textbooks, Downloads, & Other References

Last Year's Website has been archived.

Need extra disk space?  You can use your BOX and Google-Drive storage as if they were local network drives.  Having one or two 1 TB virtual network drives may be helpful when working with large datasets on a small laptop.

Key ITK Documentation:

Assignments (please do not start until assigned in the schedule)

Schedule—Subject to Change
(Future plans are tentative, based on the old 2020 schedule)

Note about videos: Lecture videos were recorded in 2012, and you can downlaod the lecture videos from the 2012 schedule here. Be sure to download the videos (right-click the video's link then select either "download" or "save-as") rather than try to watch them in your browser. Please let me know if you notice any problems or video content that should be either fixed or trimmed out if it's not relevant to a general audiance (please reference the 2012 lecture number and the playing time into the video at which the problem occurs).

Week # Date Updated for 2022? Material Video and .pptx files
Week 1
T 1/18


Lecture 1: Introductions, purpose, Syllabus

Power Point
Video (from 2012)

R 1/20

Lecture 2: Programming background:  C++ & Python

Power Point
Video (from 2012)
Week 2
M 1/20

Lecture 3: ITK background & basic usage
CMU's add/drop-with-refund period ends sometime around now.

WARNING: Quiz on book reading next class!

Note: first chapters (ch 1, ch 2) of the text book may be freely accessible by scrolling down on Google's book page.

Power Point
Video (from 2012)
W 1/22

To prepare for the quiz, I suggest focussing on big-picture concepts and major themes, what algorithms/methods are trying to do, what they are good for, and (if the text goes over it) when/how they typically fail.

Lecture 4: Math & probability background
Begin class with a short QUIZ on Snyder ch. 1-2

Power Point
Video (from 2012)
Week 3
M 1/27

Lecture 5: Image characterization (also posted on Diderot)
Quiz #2 on Snyder ch. 4 (skip hexagonal coordinates on pp 57-59)

Power Point
Video (from 2012)

W 1/29

Assignment #1  will be ready later this week 

Week 4
M 2/3

Lecture 6: Linear processing
Quiz #3 on Snyder 5.1-5.6,5.8-5A (through page 101, but skip hexagonal coordinates on pp 71-73 and skip 5.7)

Assignment #2 is ready now. Please try to do it this week.

Power Point
Video (from 2012)
W 2/5

Lecture 7: Image relaxation: restoration & feature extraction
Quiz #4 on Snyder ch. 6
HW2 due 11:59pm Monday the 11th.

Power Point
Video (from 2012)
Week 5
M 2/10

Lecture 8: ITK registration

Power Point
Video (from 2012)
W 2/12

Lecture 9: Segmentation, part 1
Quiz #5 (the most in-depth quiz of the class) on Snyder ch. 8 (skip 8.3.2 on pp. 189-196 & 8A.1.1 on pp. 208-209)

HW2 deadline extended to noon Friday Feb. 14.

Power Point
Video (from 2012)

Week 6
M 2/17

Lecture 10: Segmentation, part 1 continued (using previous notes, start with slide 8)

Shadow program starts Monday the 24th! Complete your UPMC form today.
Mini-lecture discussion of the  Shadow Program & signup procedure

Assignment #3 is now assigned, due 5pm Tuesday the 25th.

Shadow Program Power Point

W 2/19

Imaging Modalities

Shadow Program — Signed UPMC Confidentiality Forms DUE IN CLASS TODAY; be sure to sign up for the Shadow Program THIS WEEK, starting tonight at TBD. (link is here; you may be able to sign up for stations faster if you create an account on in advance).

Imaging Modalities Power Point (contains embedded movies)
Video (from 2012, skip to end for imaging modalities)

Week 7
M 2/24

Lecture 11: Segmentation, part 3 (active contours)

Follow Up: HW3—easy/helpful? Issues with web browsers, snap, or PDF?

Shadow Program starts TODAY--show up on your days at 8 am (with UPMC form!) until you know where you're going
How is the shadow program going?

Follow Up: HW3—easy/helpful? MS Edge & PDF? Shadow?

Power Point
Video (from 2012)

W 2/26

Lecture 12: Level set segmentations & parametric transforms (Snyder 8.5.2 & Snyder 11.1-11.6) [not required, but recommended: Insight into Images ch 8]
Quiz on Snyder 11.1-11.6

Assignment #4 is now assigned, due midnight Friday the 6th. 

Final Project Power Point

Power Point
Video (from 2012)



  M 3/2  

Finish Lecture 12: (Level set segmentations &) Parametric Transforms

Discuss final projects
Be sure to email me your initial project idea / tentative proposal by the night of Tuesday the 17th.
Go over example projects.

Assignment #4 was assigned last Friday, due midnight Friday the 6th.


  W 3/4  

Lecture: ITK images & iterators

Segmentation Assignment has now been assigned, on Friday the 6th

Power Point
Video (from 2012)
Spring Break
3/9 - 3/11
  Spring Break (Segmentation Assignment now assigned, due Thursday night, the 26th)  
Week 8
M 3/16


Initial project proposals due tonight.

W 3/18

COVID-19:  PITT CLASSES DELAYED, MIMIA not having class today.  Lectures will resume on Monday 23rd in an online format.  More details will be coming. 

Week 9
M 3/23

Note:  Zoom link  We will (attempt to) do the quiz online on Canvas, after we get class started.  Zoom recording.

Lecture 14: Shape
Quiz on Snyder ch. 9 (read 9.1-9.8, 9.12-9.14)

Lecture 15: Summarize Cootes and Taylor ASM (Cootes CVIU 1995)

Segmentation assignment due midnight Thursday April 2 (1-week extension due to COVID-19). Use svn to add and committ your .mha segmentation images.

Power Point (shape)
Video (from 2012)

Power Point (public version of ASM)

W 3/25

Zoom link Lecture 13 Registration in depth (Insight into Images ch 10 + Viola & WellsZoom recording

note: Project feedback should be given by Monday night.

Power Point
Video (from 2012)

Week 10
M 3/30

Lecture 16 Mathematical morphology & image matching  Zoom Recording
Quiz on Snyder 7.1-7.5 & 13.1-13.5 will be posted on Canvas.

Project feedback should be given by later night.

Power Point
Video (from 2012)
W 4/1

Lecture 17 Deformable registration (Insight into Images ch 11) ; may start ITK Filters.  Zoom Recording

Power Point
Video (from 2012)

Week 11
M 4/6


Lecture 18: ITK filters: how to write them (neighborhoods, image boundaries, & numeric traits)

Discuss project timeline. 

(Zoom apparently stopped working (and then crashed) as we were trying to take the last question in class.   Please email any remaining questions. 

Power Point (ITK Filters)
Video (from 2012)

W 4/8

AWS Credits will be issued (for GPU and/or CPU cloud computing)   To use, first create an account on the AWS Educate portal using your andrew ID. Will discuss important  details in class.

Discuss deep learning.
Only if time (doubtful):  Summarize Lecture 20: ITK Paths

Shadow Program makeup still TBD, hope to announce details by Friday.

Power Point
Video (from 2012)


Week 12
M 4/13

Student project working time, professor meetings, and/or possible Shadow options.

W 4/15

Student project presentation slides and videos will be due 10:30am Monday morning!
Presentation order to be assigned over weekend--email (only hard) conflicts today!

Week 12
M 4/20

Student project presentation using pre-recorded videos (see random order email)
(Each presentation must be 8.0-12.0 minutes long.)
Everyone's videos AND powerpoint slides due by 10:30 AM today! (.mp4 and .pptx formats preferred, or else .mov, .ppt, or .pdf)

Important: Your presentation should use this directory and name format:

W 4/22
  Student project presentations (presentation order)  
Week 13
M 4/27

Student project presentations (presentation order)

W 4/29
  Student project presentations & Projects Due;  All 6 shadow reprots due May 6th at noon.