I am the Ray and Stephanie Lane Professor of Computational Biology in the School of Computer Science at Carnegie Mellon University. I also have an Affiliated Faculty appointment in Machine Learning. Our group started at the University of Illinois at Urbana-Champaign in August 2009. We moved to Carnegie Mellon in January 2016. I have been fortunate to receive a few awards, including, among others, being named "Tomorrow's PI" by Genome Technology (2011), a National Science Foundation CAREER award (2011), and a Guggenheim Fellowship (2020).
The main focus of our ongoing research is the development of machine learning algorithms to study the structure and function of the human genome and cellular organization and their implications for health and disease. We also work on machine learning methods for cohesive integration of multimodal biomedical data and for enhancing model interpretability and generalizability. Recent interests include nuclear genome organization, single-cell epigenomics, spatial omics, comparative genomics, and complex molecular interactions.
Our lab is leading a UM1 Center in the NIH 4D Nucleome (4DN) Program [CMU News]. I am also serving as Co-Chair of the Steering Committee of the NIH 4DN Program. In addition, our lab is involved in the NIH SenNet Consortium and the IGVF Consortium.