I am the Ray and Stephanie Lane Professor of Computational Biology in the School of Computer Science at Carnegie Mellon University. I also have an Affiliated Faculty appointment in Machine Learning. Our group started at the University of Illinois at Urbana-Champaign in August 2009. We moved to Carnegie Mellon in January 2016. I have been fortunate to receive a few awards, including, among others, being named "Tomorrow's PI" by Genome Technology (2011), a National Science Foundation CAREER award (2011), and a Guggenheim Fellowship (2020).
The main focus of our ongoing research is the development of machine learning algorithms to reveal fundamental connections between human genome structure and function and their implications in human diseases. We also work on machine learning methods for cohesive integration of multimodal biomedical data and for enhancing model interpretability and generalizability. Recent interests include nuclear genome organization, single-cell epigenomics, spatial omics, comparative genomics, and complex molecular interactions. Our lab is currently leading a UM1 Center in the Phase 2 of NIH 4D Nucleome Program [CMU News].