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We listed below a collection of interesting web sites of projects and researchers which are very much related to the Sangria Project escope. Clicking on a thumbnail will take you to the original web site.

Blood Circulation and the Heart.
Charles S. Peskin and David M. McQueen, New York University, Courant Institute of Mathematical Sciences.

It's not everyday new life comes into being as a result of calculations on a supercomputer. But it's not much of an exaggeration to say that's what happened when Charles Peskin and David McQueen cranked up their heart model for the first time on the Pittsburgh Supercomputing Center's CRAY C90. (more...)
Simulation of cardiovascular and other biomedical problems.
AEA Technology Engineering Software

The project will produce a simulation tool to study the human cardiovascular system, and will advance significantly the use of simulation within the bio-medical community at a time when the use of prostheses is increasing substantially and clinicians are participating as never before in the engineering of organ replacements. The increasing availability of relatively inexpensive High-Performance Computing and Networking (HPCN) means that these problems are, for the first time, tractable. (more...)
Medical Devices and Artificial Organs
McGowan Institute for Regenerative Medicine

To realize the vast potential of tissue engineering and other techniques aimed at repairing damaged or diseased tissues and organs, the University of Pittsburgh School of Medicine and UPMC Health System have established the McGowan Institute for Regenerative Medicine (MIRM). As an entity, the MIRM will serve as a single base of operations for the university's leading scientists and clinical faculty working to develop tissue engineering, cellular therapies, biosurgery and artificial and biohybrid organ devices. (more...)

 

David A. Steinman, Ph.D.
The Biomedical Simulation Lab.
"Research interests in Hemodynamics Factors in Atherogenesis, Improving Stroke Risk Assessment, Optimization of Bypass Graft Surgery, Virtual MRI and Doppler Ultrasound, Visualization of Pulsatile Flow, 3D Reconstruction of Vascular Anatomy, and Turbulence and Pulsatile Flow."
Danny Bluestein, Assistant Professor
Department of Biomedical Engineering, SUNY Stony Brook
"My primary research interests are in biofluids and cardiovascular pathologies. I am studying blood flow in the cardiovascular system, with a special interest in flow induced cardiovascular pathologies, and the design optimization of cardiovascular prostheses. I envision to bring recent advancements made in various fields, namely numerical modeling, non-invasive flow measurement techniques, and innovative blood measurement techniques, to better understand the mechanisms underlying cardiovascular pathologies such as stenoses, aneurysms, thrombus formation, and pathological flow fields past prosthetic heart valves and various blood recirculating devices that may lead to cardioembolic strokes."
George Biros, Associate Professor
College of Computing and College of Engineering, Georgia Institute of Technology
"George Biros's research interests include parallel computing, integral and differential equations, inverse problems, biological complex fluids, soft tissue and cardiovascular mechanics, and medical image analysis "
Daniel D. Joseph, Professor, Regents and Russell J. Penrose Professor Emeritus
Aerospace Engineering and Mechanics, University of Minnesota
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Michael R. King, Associate Professor
Chemical Engineering, University of Rochester
"The King laboratory seeks to understand all aspects of the dynamic interactions between blood, circulating cells, and the tissues that they contact. In particular, the balance between hydrodynamic shear forces and chemical adhesive interactions presents the most scientifically interesting aspect of this field currently, as well as being an area with great potential to impact public health through its relevance to cancer, cardiovascular disease, and inflammation. The ultimate goal of our laboratory is a complete, predictive numerical simulation of blood flow that includes all relevant cellular interactions. The surface interactions between cells in suspension or between suspended cells and the vessel wall is where we stand to make the largest contribution to the field, as a rigorous treatment of particulate flow in a biologically realistic setting has never been previously attempted. One of the greatest challenges that we have faced and will continue to address is the need to bridge multiple length scales: from deviation bond lengths measured at tens of nanometers, to micron-sized blood cells, to larger vessels several millimeters in diameter. Continuum rheological models at the artery scale must be matched in a seamless way with the multiparticle adhesive dynamics (MAD) simulation that is able to consider nearfield interactions during cell-cell or cell-wall collisions. We have already succeeded in reconciling bond compliance and kinetics in a cellular-scale calculation. Our research will progress from code development and in vitro experimentation, to later comparison of MAD with experimental animal models, to finally correlating MAD results to patient data. "
Aaron Fogelson, Professor
Department of Mathematics, University of Utah

 

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