Research

Local quality assessment for optical coherence tomography

 

Optical Coherence Tomography (OCT) is a non-invasive tool for visualizing the retina. It is increasingly used to diagnose eye diseases such as glaucoma and diabetic maculopathy. However, diagnosis is only possible when the layers of the retina can be easily distinguished, which is when the images are evenly illuminated. Automated OCT quality assessment (i.e. signal strength) is only available for images as a whole. In this work, we present an automated method for local quality assessment. For training data, three OCT experts label the quality of each individual a-scan line in 270 OCT images. We extract features that are insensitive to pathology, and employ a hierarchy of support vector machines and histogram-based metrics. Our trained classifier is able to determine not only when signal strength is low, but also when it will affect doctors’ diagnostic ability. Our results improve over the state of the art in OCT quality assessment.

Publications

"Local quality assessment for optical coherence tomography,"
P. Barnum, M. Chen, H. Ishikawa, G. Wollstein, and J. Schuman
International Symposium on Biomedical Imaging (ISBI), May 2008.
[PDF] [Poster]
 
"Pathology Insensitive Quality Assessment for Optical Coherence Tomography,"
P. Barnum, M. Chen, H. Ishikawa, G. Wollstein, and J. Schuman
Association for Research in Vision and Ophthalmology (ARVO), April 2008.
[Abstract]