RE: New treatments for pancreatic cancer From: <David.Raben@UCHSC.edu> To: <pausch@cmu.edu> Date: Dec 31 1969 - 7:00pm here is our newsletter at Colorado regarding our Phase I/II trials - see highlighted ones as well David Raben, M.D. University of Colorado Denver Department of Radiation OncologyAnschutz Medical Campus1665 North Ursula Street, Suite 1032PO Box 6510, Mail Stop F-706Aurora, CO 80045________________________________From: Randy Pausch [mailto:pausch@cmu.edu]Sent: Thu 12/6/2007 11:52 AMTo: Raben, DavidSubject: Re: New treatments for pancreatic cancerDrat - I'm so sorry, but it just doesn't seem to work.I greatly appreciate your help: my fax # is (801) 788-2245thanks!!!!! RandyDavid.Raben@UCHSC.edu wrote: does this work - if not, I will fax to you David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 ________________________________ From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Thu 12/6/2007 8:41 AM To: Raben, David Subject: Re: New treatments for pancreatic cancer Thanks - greatly appreciated!!! Randy David.Raben@UCHSC.edu wrote: was a powerpoint presentation - will try some other ways if possible David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 ________________________________ From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Wed 12/5/2007 8:00 PM To: Raben, David Subject: Re: New treatments for pancreatic cancer Argh! I don't think the problem is size, so much as something is going wrong. What type of file is this supposed to be? I'm getting an attachment called winmail.dat and my computer has no idea what application to use to open it. Sorry to be a pain, but I'd (obviously) like to be able to read this information!!! thanks, Randy David.Raben@UCHSC.edu wrote: Try this - condensed everything David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 ________________________________ From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Sun 12/2/2007 9:57 PM To: Raben, David Subject: Re: New treatments for pancreatic cancer Dr. Raben, Unfortunately, the attachment appears to be corrupted in some way - could I trouble you to resend it? I will keep anything you send me confidential... thanks, Randy David.Raben@UCHSC.edu wrote: Here are some slides on it - please keep confidential - these will give you some info in activity in mice and in humans. i will touch base with wells if there is a specific trial at JHH for pancreatic or perhaps we can get you compassionate use - might be worth a shot David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 -----Original Message----- From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Sun 12/2/2007 12:15 PM To: Raben, David Cc: Messersmith, Wells Subject: Re: New treatments for pancreatic cancer Dr. Raben, I'd be quite interested in more information on the kinase inhibitors - is it available on the web, or are there documents you can send me? thanks, Randy David.Raben@UCHSC.edu wrote: Dear Randy, I saw your article in a major British paper today while here in Manchester on Sabbatical for cancer research. I have a strong interest in pancreatic cancer along with my colleagues at the Univ of Colorado Denver. I would be honored if I could help you and may be able to assist you in getting access to some new drugs that appear promising in inhibiting metastatic disease from progressing using Src kinase inhibition. I am sure you are already plugged into Phase I therapy options in your area but we also have a very strong Phase I therapeutics program under Gail Eckhardt (you can certainly google us to get further info). I am doing research with Astrazeneca and again we are working on a drug taken orally that inhibits src kinase and in pancreatic models it appeared quite interesting - it is in human Phase I and II trials currently. If I could help you get access to this drug or get into our Phase I clinic at Colorado I would be happy to help. Wells Messersmi th has recentl y joined us from Johns Hopkins and he has a specific interest in pancreatic research and has done work with this compound as well. Your story reminded me of a movie many years ago with Michael Keaton when he films video's to leave to his kids which was very moving as was your story. David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 -- Randy Pausch pausch@cmu.edu, www.randypausch.com <http://www.randypausch.com/> <http://www.randypausch.com/> <http://www.randypausch.com/> , (412) 268-3579 Professor of Computer Science, HCI, and Design Director, Alice Project (www.alice.org <http://www.alice.org/> <http://www.alice.org/> <http://www.alice.org/> ) Co-Founder, Entertainment Technology Center (www.etc.cmu.edu <http://www.etc.cmu.edu/> <http://www.etc.cmu.edu/> <http://www.etc.cmu.edu/> ) Carnegie Mellon University, School of Computer Science 5000 Forbes Avenue, Pittsburgh, PA 15219 -- Randy Pausch pausch@cmu.edu, www.randypausch.com <http://www.randypausch.com/> , (412) 268-3579 Professor of Computer Science, HCI, and Design Director, Alice Project (www.alice.org <http://www.alice.org/> ) Co-Founder, Entertainment Technology Center (www.etc.cmu.edu <http://www.etc.cmu.edu/> ) Carnegie Mellon University, School of Computer Science 5000 Forbes Avenue, Pittsburgh, PA 15219 -- Randy Pauschpausch@cmu.edu, www.randypausch.com <http://www.randypausch.com/> , (412) 268-3579Professor of Computer Science, HCI, and DesignDirector, Alice Project (www.alice.org <http://www.alice.org/> )Co-Founder, Entertainment Technology Center (www.etc.cmu.edu <http://www.etc.cmu.edu/> )Carnegie Mellon University, School of Computer Science5000 Forbes Avenue, Pittsburgh, PA 15219
From: <David.Raben@UCHSC.edu> To: <pausch@cmu.edu> Date: Dec 31 1969 - 7:00pm
here is our newsletter at Colorado regarding our Phase I/II trials - see highlighted ones as well David Raben, M.D. University of Colorado Denver Department of Radiation OncologyAnschutz Medical Campus1665 North Ursula Street, Suite 1032PO Box 6510, Mail Stop F-706Aurora, CO 80045________________________________From: Randy Pausch [mailto:pausch@cmu.edu]Sent: Thu 12/6/2007 11:52 AMTo: Raben, DavidSubject: Re: New treatments for pancreatic cancerDrat - I'm so sorry, but it just doesn't seem to work.I greatly appreciate your help: my fax # is (801) 788-2245thanks!!!!! RandyDavid.Raben@UCHSC.edu wrote: does this work - if not, I will fax to you David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 ________________________________ From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Thu 12/6/2007 8:41 AM To: Raben, David Subject: Re: New treatments for pancreatic cancer Thanks - greatly appreciated!!! Randy David.Raben@UCHSC.edu wrote: was a powerpoint presentation - will try some other ways if possible David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 ________________________________ From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Wed 12/5/2007 8:00 PM To: Raben, David Subject: Re: New treatments for pancreatic cancer Argh! I don't think the problem is size, so much as something is going wrong. What type of file is this supposed to be? I'm getting an attachment called winmail.dat and my computer has no idea what application to use to open it. Sorry to be a pain, but I'd (obviously) like to be able to read this information!!! thanks, Randy David.Raben@UCHSC.edu wrote: Try this - condensed everything David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 ________________________________ From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Sun 12/2/2007 9:57 PM To: Raben, David Subject: Re: New treatments for pancreatic cancer Dr. Raben, Unfortunately, the attachment appears to be corrupted in some way - could I trouble you to resend it? I will keep anything you send me confidential... thanks, Randy David.Raben@UCHSC.edu wrote: Here are some slides on it - please keep confidential - these will give you some info in activity in mice and in humans. i will touch base with wells if there is a specific trial at JHH for pancreatic or perhaps we can get you compassionate use - might be worth a shot David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 -----Original Message----- From: Randy Pausch [mailto:pausch@cmu.edu] Sent: Sun 12/2/2007 12:15 PM To: Raben, David Cc: Messersmith, Wells Subject: Re: New treatments for pancreatic cancer Dr. Raben, I'd be quite interested in more information on the kinase inhibitors - is it available on the web, or are there documents you can send me? thanks, Randy David.Raben@UCHSC.edu wrote: Dear Randy, I saw your article in a major British paper today while here in Manchester on Sabbatical for cancer research. I have a strong interest in pancreatic cancer along with my colleagues at the Univ of Colorado Denver. I would be honored if I could help you and may be able to assist you in getting access to some new drugs that appear promising in inhibiting metastatic disease from progressing using Src kinase inhibition. I am sure you are already plugged into Phase I therapy options in your area but we also have a very strong Phase I therapeutics program under Gail Eckhardt (you can certainly google us to get further info). I am doing research with Astrazeneca and again we are working on a drug taken orally that inhibits src kinase and in pancreatic models it appeared quite interesting - it is in human Phase I and II trials currently. If I could help you get access to this drug or get into our Phase I clinic at Colorado I would be happy to help. Wells Messersmi th has recentl y joined us from Johns Hopkins and he has a specific interest in pancreatic research and has done work with this compound as well. Your story reminded me of a movie many years ago with Michael Keaton when he films video's to leave to his kids which was very moving as was your story. David Raben, M.D. University of Colorado Denver Department of Radiation Oncology Anschutz Medical Campus 1665 North Ursula Street, Suite 1032 PO Box 6510, Mail Stop F-706 Aurora, CO 80045 -- Randy Pausch pausch@cmu.edu, www.randypausch.com <http://www.randypausch.com/> <http://www.randypausch.com/> <http://www.randypausch.com/> , (412) 268-3579 Professor of Computer Science, HCI, and Design Director, Alice Project (www.alice.org <http://www.alice.org/> <http://www.alice.org/> <http://www.alice.org/> ) Co-Founder, Entertainment Technology Center (www.etc.cmu.edu <http://www.etc.cmu.edu/> <http://www.etc.cmu.edu/> <http://www.etc.cmu.edu/> ) Carnegie Mellon University, School of Computer Science 5000 Forbes Avenue, Pittsburgh, PA 15219 -- Randy Pausch pausch@cmu.edu, www.randypausch.com <http://www.randypausch.com/> , (412) 268-3579 Professor of Computer Science, HCI, and Design Director, Alice Project (www.alice.org <http://www.alice.org/> ) Co-Founder, Entertainment Technology Center (www.etc.cmu.edu <http://www.etc.cmu.edu/> ) Carnegie Mellon University, School of Computer Science 5000 Forbes Avenue, Pittsburgh, PA 15219 -- Randy Pauschpausch@cmu.edu, www.randypausch.com <http://www.randypausch.com/> , (412) 268-3579Professor of Computer Science, HCI, and DesignDirector, Alice Project (www.alice.org <http://www.alice.org/> )Co-Founder, Entertainment Technology Center (www.etc.cmu.edu <http://www.etc.cmu.edu/> )Carnegie Mellon University, School of Computer Science5000 Forbes Avenue, Pittsburgh, PA 15219
RE: New treatments for pancreatic cancer
