Activation of Genes by ATF4 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Acute myeloid leukemia Adaptive Immune System ALK1 pathway ALK1 signaling events Allograft rejection Alpha6Beta4Integrin Alpha9 beta1 integrin signaling events Androgen-mediated signaling AndrogenReceptor Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen processing and presentation Antigen processing-Cross presentation AP-1 transcription factor network Arf6 downstream pathway Arf6 signaling events Arf6 trafficking events ascorbate recycling (cytosolic) Asthma ATM pathway ATR signaling pathway Autoimmune thyroid disease Axon guidance BCR signaling pathway Beta1 integrin cell surface interactions Beta2 integrin cell surface interactions BMP receptor signaling Canonical Wnt signaling pathway Cap-dependent Translation Initiation Carbohydrate digestion and absorption CDC42 signaling events Cell adhesion molecules (CAMs) Cell Cycle Cell Cycle, Mitotic Cell surface interactions at the vascular wall Chaperonin-mediated protein folding Chromosome Maintenance Class I MHC mediated antigen processing & presentation Class I PI3K signaling events Class I PI3K signaling events mediated by Akt Clathrin derived vesicle budding C-MYB transcription factor network C-MYC pathway Collagen biosynthesis and modifying enzymes Collagen formation Costimulation by the CD28 family CXCR3-mediated signaling events CXCR4-mediated signaling events Cytokine Signaling in Immune system DAP12 interactions DAP12 signaling Developmental Biology Diabetes pathways Digestion of dietary carbohydrate Disease DNA Replication Downstream Signaling Events Of B Cell Receptor (BCR) Downstream signaling of activated FGFR Downstream signal transduction Downstream TCR signaling E-cadherin signaling events E-cadherin signaling in the nascent adherens junction ECM-receptor interaction EGFR1 EGFR-dependent Endothelin signaling events EGF receptor (ErbB1) signaling pathway Endocytosis Endosomal/Vacuolar pathway Endothelins Enzymatic degradation of dopamine by COMT Enzymatic degradation of Dopamine by monoamine oxidase Epstein-Barr virus infection ErbB1 downstream signaling ErbB receptor signaling network ER-Phagosome pathway Eukaryotic Translation Elongation Eukaryotic Translation Initiation Extracellular matrix organization FAS (CD95) signaling pathway Focal adhesion Formation and Maturation of mRNA Transcript Formation of Platelet plug G2/M Transition GAB1 signalosome Gene Expression Generation of second messenger molecules Generic Transcription Pathway Glucocorticoid receptor regulatory network Glucocorticoid receptor signaling Glypican 1 network Glypican 3 network Glypican pathway GMCSF-mediated signaling events Golgi Associated Vesicle Biogenesis Graft-versus-host disease Hemostasis Herpes simplex infection HIF-1-alpha transcription factor network HIV Infection Host Interactions of HIV factors HTLV-I infection Hypoxic and oxygen homeostasis regulation of HIF-1-alpha ID IFN-gamma pathway IGF1 pathway IL12-mediated signaling events IL1-mediated signaling events IL3-mediated signaling events IL4-mediated signaling events IL5-mediated signaling events Immune System Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Influenza A Innate Immune System Insulin-mediated glucose transport Insulin Pathway Insulin Synthesis and Processing Integrin alphaIIb beta3 signaling Integrin cell surface interactions Integrin family cell surface interactions Interferon alpha/beta signaling Interferon gamma signaling Interferon Signaling Internalization of ErbB1 Iron uptake and transport Lipid digestion, mobilization, and transport LKB1 signaling events Lysosome Vesicle Biogenesis Meiosis Meiotic Synapsis Membrane Trafficking Metabolism Metabolism of carbohydrates Metabolism of lipids and lipoproteins Metabolism of mRNA Metabolism of proteins Metabolism of RNA MHC class II antigen presentation Mitotic G2-G2/M phases Mitotic M-M/G1 phases mRNA Processing mRNA Splicing mRNA Splicing - Major Pathway mTOR signaling pathway N-cadherin signaling events NCAM1 interactions NCAM signaling for neurite out-growth Nectin adhesion pathway Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters Noncanonical Wnt signaling pathway NOTCH1 Intracellular Domain Regulates Transcription p38 MAPK signaling pathway p53 pathway p63 transcription factor network p75 NTR receptor-mediated signalling PAR1-mediated thrombin signaling events Pathways in cancer PD-1 signaling PDGFR-beta signaling pathway PDGF receptor signaling network Peptide chain elongation PERK regulated gene expression Phagosome Phosphorylation of CD3 and TCR zeta chains PI3K/AKT activation PI3K/AKT Signaling in Cancer PI3K/AKT signalling PI-3K cascade PI3K events in ERBB2 signaling PI3K events in ERBB4 signaling PIP3 activates AKT signaling Plasma membrane estrogen receptor signaling Platelet Activation Platelet activation, signaling and aggregation Platelet activation triggers Platelet Aggregation (Plug Formation) Platelet degranulation PLK1 signaling events Polo-like kinase signaling events in the cell cycle Posttranslational regulation of adherens junction stability and dissassembly Processing of Capped Intron-Containing Pre-mRNA Protein folding Proteoglycan syndecan-mediated signaling events RAC1 signaling pathway Regulation of Androgen receptor activity Regulation of CDC42 activity Regulation of cytoplasmic and nuclear SMAD2/3 signaling Regulation of Insulin Secretion Regulation of mRNA Stability by Proteins that Bind AU-rich Elements Regulation of nuclear beta catenin signaling and target gene transcription Regulation of nuclear SMAD2/3 signaling Regulation of RAC1 activity Regulation of RhoA activity Release of eIF4E Response to elevated platelet cytosolic Ca2+ RhoA signaling pathway Rho GTPase cycle Ribosomal scanning and start codon recognition RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways S1P1 pathway Semaphorin interactions Signaling by EGFR Signaling by EGFR in Cancer Signaling by ERBB2 Signaling by ERBB4 Signaling by FGFR Signaling by FGFR in disease Signaling by NOTCH Signaling by NOTCH1 Signaling by PDGF Signaling by Rho GTPases Signaling by SCF-KIT Signaling by the B Cell Receptor (BCR) Signaling events mediated by focal adhesion kinase Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) Signaling events mediated by TCPTP Signaling events mediated by VEGFR1 and VEGFR2 Signaling in Immune system Signalling by NGF Signal Transduction Sphingosine 1-phosphate (S1P) pathway Stabilization and expansion of the E-cadherin adherens junction Staphylococcus aureus infection Syndecan-1-mediated signaling events Syndecan-4-mediated signaling events TCR signaling TCR signaling in naive CD4+ T cells TGF-beta receptor signaling TGFBR The role of Nef in HIV-1 replication and disease pathogenesis Thrombin/protease-activated receptor (PAR) pathway TNF alpha/NF-kB TNF receptor signaling pathway Toxoplasmosis TRAIL signaling pathway trans-Golgi Network Vesicle Budding Translation Translation initiation complex formation Translocation of ZAP-70 to Immunological synapse Transmembrane transport of small molecules Tuberculosis Type I diabetes mellitus Unfolded Protein Response Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling Validated targets of C-MYC transcriptional repression Validated transcriptional targets of AP1 family members Fra1 and Fra2 Viral carcinogenesis Viral myocarditis Wnt signaling network