Eric Poe Xing

605 Ohlone Ave. #620
Albany, CA 94706
510-527-6156 (home), 510-486-4923 (office)
e-mail: epxing@cs.berkeley.edu


Education

Ph.D. Student, Computer Science 1999- Department of Electrical Engineering and Computer Science, UC Berkeley, California
 
Ph.D., Biochemistry and Molecular Biology 1994-1999
          Joint Graduate Program of Molecular BioSciences, Rutgers University, New Jersey

M.S., Computer Science (double major) 1996-1998
          Department of Computer Science, Rutgers University

B.S., Physics 1988-1993
          Department of Physics, Tsinghua University, Beijing, China

          Molecular Biology (minor) 1990-1993
          Department of Biological Sciences and Biotechnology, Tsinghua University.

Honors and Awards Professional and Research Experience
Present:

Graduate Fellow, Computer Science Division, UC Berkeley, 1999-
                                     Advisors: Professors Richard Karp, Stuart Russell and Michael Jordan

Research interest:

Past:

Computer Scientist, National Energy Research Scientific Computing Division, Lawrence Berkeley National Laboratory, 1999-2000
 


Research Assistant, Lab for Cancer Research, College of Pharmacy, Rutgers University (1995-1999).
                                     (Serve as Leader of Carcinogenesis Topic Group since 1997)
                                      Advisor: Professors Chung S. Yang
 


Research Assistant, Department of Computer Science, Rutgers University (1996-1998).
                                     Advisor: Professor Casimir Kulikowski
 


Research Scientist, National Institute of Metrology, Chinese National Standards Bureau (1993-1994).
 


Research Assistant, Lab of Atomic and Molecular Physics, Tsinghua University (1991-1993).
 

Professional Organizations American Association for Cancer Research. Associate member since 1997.
The International Society for Computational Biology, member since 2001.
Hobbies and Extracurricular activities Classical arts and literature, travel, sports.

Interesting experiences:

Summary of Skills and Qualifications Computer skill:
 

List of Publications


A) Journals:

  1. Xing E.P., Spengler S., Zorn M., Muchnik I., Classification of multi-aligned sequence using monotone linkage clustering and alignment segmentation. Manuscript in preparation.

  2.  
  3. Xing E.P., Wolf D., Dubchak I., Spengler S., Zorn M., Kulikowski C., Muchnik I., Automatic discovery of sub-molecular sequence domains in multi-aligned sequences: a dynamic programming algorithm for multiple alignment segmentation, Journal of Theoretical Biology, 2001 Sep 21;212(2):129-39.

  4.  
  5. Xing E.P., Karp R.M., CLIFF: clustering of high-dimensional microarray data via iterative feature filtering using normalized cuts. Bioinformatics. 2001 Jun;17 Suppl 1:S306-15.

  6.  
  7. Cai Y., Yang G-Y., Yan N., Wang L-D., Zhao X., Song Y-L., Seril D., Liao J., Xing E.P. and Yang C.S., Molecular alteration of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53.  Carcinogenesis, 2000; 21(4):683-9.

  8.  
  9. Xing E.P., Wu W., Wang L., Zhao X. and Yang C.S., Comparative Analysis of p53 Mutational Spectrum of Esophageal Squamous Cell Carcinoma from Linxian, China with Spectra of Other ESCC and Other Cancers, Carcinogenesis, 2001, in press.

  10.  
  11. Xing E.P., Nie Y., Song Y-L., Yang G-Y., Cai C. C., Wang L-D., Chung C. S., Mechanisms of inactivation of p14ARF, p15INK4b and p16INK4a genes in human esophageal squamous cell carcinoma: p14ARF is potentially another inactivation hotspot within the 9p21 gene cluster,  Clinical Cancer Research, 1999 Oct; 5(10): 2704-13.

  12.  
  13. Xing E. P., Yang G-Y., Wang L-D., Yang C. S., Loss of Heterozygous of the Rb gene correlates with pRb protein expression and associates with p53 alteration in human esophageal cancer. Clinical Cancer Research, 1999 May; 5(5): 1231-40.

  14.  
  15. Shi S.T., Yang G-Y., Xue Z., Feng B., Ding W., Wang L-D., Xing E. P. and Yang C. S., Role of p53 gene mutation in human esophageal carcinogenesis: result from immunohistochemistry and mutation analysis of carcinomas and nearby non-cancerous lesions, Carcinogenesis, 1999 Apr; 20(4): 591-7.

  16.  
  17. Xing E. P., Nie Y., Wang L-D., Yang G-Y., Yang C.S., Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer, Carcinogenesis, 1999 Jan; 20(1): 77-84.

  18.  

     

B) Conference Proceedings and Technical Reports:
  1. Xing E.P.,  Jordan M., and Karp R., Dimensionality reduction using a mixture of feature evaluation

  2. systems in classification of high-dimensional molecular biology data. Proceedings of the Eighteenth International Conference on Machine Learning (ICML 2001).
     
  3. Xing E.P., and Karp R., CINCAFF: Clustering via Iterative Normalized Cut and Feature Filtering of high-dimensional microarray data, Proceedings of The Nineth International Conference on Intelligence Systems for Molecular Biology (ISMB 2001).

  4.  
  5. Xing, E.P., Kulikowski, C., Muchnik, I., Dukchak, I., Wolf, D., Spengler, S. and Zorn, M. Analysis of ribosomal RNA sequences by combinatorial clustering. Proceedings, The Seventh International Conference on Intelligence Systems for Molecular Biology (ISMB99), (Eds. T. Lengauer et al.) AAAI/MIT Press, Menlo Park, CA. P. 287-296..

  6.  
  7. Xing E.P., Yang G-Y, Wang L-D., Yang C.S., The molecular alterations of tumor suppressor genes p16INK4a and p15INK4b in human esophageal cancer, Proceedings of The American Association For Cancer Research, Vol 39:442, 1998.

  8.  
  9. Xing E.P., Shi S.T., Wang L-D., Yang C.S., Loss of heterozygosity in Rb gene and its relationship with p53 alteration in esophageal cancer, Proceedings of The American Association For Cancer Research, Vol 38:510-511, 1997.

  10.  
  11. Xue P., Xing P., Huang Y., Zhao J., The Research of Continuous Tunable High-Pressure Electron-Beam-Controlled CO2 Laser, Proceedings of the 1993 Shanghai World Optical Conference, 1993.


C) Invited Talks:

  1. Feature selection for high-dimensional genomic microarray data in concept learning and clustering analysis. AMS-IMS-SIAM Summer Research Conference:  Statistics in Functional Genomics, June 10 - Thursday, June 14, 2001, South Hadley, MA, USA.