SCS Teaching Track Faculty Candidate Talk

  • Ph.D. Candidate
  • Department of Mathematics
  • University of California, San Diego

Pancakes, Graphs, and Fragile Genomes

Finding mathematical models for the comparison of two genomes is a fundamental challenge in modern biology. Surprisingly, a very simple graph-theoretical model has produced a large number of theoretical results and has proven to be robust when analyzing real genomes. One practical question, which we will address, is whether large-scale mutations appear random or whether genomes have "fragile" regions, which are being mutated over and over during the course of species evolution.


Phillip Compeau is a Ph.D. candidate in the University of California, San Diego (UCSD) Department of Mathematics. He researches the combinatorics of genome rearrangements and is passionate about the future of education, having co-created the first massive open online course (MOOC) in bioinformatics ( and co-founded Rosalind (, a platform for learning bioinformatics through problem solving.

Faculty Host: Klaus Sutner

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