Category ID Category Name #Genes Category #Genes Assigned #Genes Expected #Genes Enriched p-value Corrected p-value GO:0005578 extracellular matrix (sensu Metazoa) 153 14 1.4 12.6 7.20E-11 <0.001 GO:0044421 extracellular region part 381 19 3.5 15.5 7.70E-10 <0.001 GO:0005201 extracellular matrix structural constituent 48 8 0.4 7.6 9.60E-09 <0.001 GO:0007155 cell adhesion 378 13 3.5 9.5 3.30E-05 0.075 GO:0044420 extracellular matrix part 118 7 1.1 5.9 9.60E-05 0.222 GO:0008283 cell proliferation 371 12 3.4 8.6 1.20E-04 0.284 GO:0048513 organ development 377 12 3.5 8.5 1.40E-04 0.331 GO:0008015 circulation 72 5 0.7 4.3 4.90E-04 1 GO:0005509 calcium ion binding 439 12 4 8 5.80E-04 1 GO:0042127 regulation of cell proliferation 213 8 2 6 7.00E-04 1 GO:0008285 negative regulation of cell proliferation 118 6 1.1 4.9 7.10E-04 1 GO:0030246 carbohydrate binding 119 6 1.1 4.9 7.40E-04 1 GO:0005615 extracellular space 259 8 2.4 5.6 2.40E-03 1 GO:0001501 skeletal development 105 5 1 4 2.70E-03 1 GO:0050874 organismal physiological process 1068 19 9.8 9.2 2.80E-03 1 GO:0048523 negative regulation of cellular process 491 11 4.5 6.5 4.80E-03 1 GO:0008219 cell death 359 9 3.3 5.7 5.30E-03 1 GO:0016265 death 359 9 3.3 5.7 5.30E-03 1 GO:0048519 negative regulation of biological process 522 11 4.8 6.2 7.60E-03 1 GO:0051243 negative regulation of cellular physiological process 452 10 4.2 5.8 7.90E-03 1 GO:0043118 negative regulation of physiological process 463 10 4.3 5.7 9.30E-03 1 GO:0016020 membrane 2316 31 21.3 9.7 9.70E-03 1 GO:0040011 locomotion 162 5 1.5 3.5 0.02 1 GO:0051674 localization of cell 162 5 1.5 3.5 0.02 1 GO:0006928 cell motility 162 5 1.5 3.5 0.02 1 GO:0042981 regulation of apoptosis 233 6 2.1 3.9 0.02 1 GO:0009605 response to external stimulus 301 7 2.8 4.2 0.02 1 GO:0043067 regulation of programmed cell death 234 6 2.2 3.8 0.02 1 GO:0006955 immune response 462 9 4.2 4.8 0.02 1 GO:0006915 apoptosis 342 7 3.1 3.9 0.04 1 GO:0012501 programmed cell death 342 7 3.1 3.9 0.04 1 GO:0008092 cytoskeletal protein binding 205 5 1.9 3.1 0.04 1 GO:0006952 defense response 506 9 4.6 4.4 0.04 1 GO:0012505 endomembrane system 215 5 2 3 0.05 1 GO:0043169 cation binding 1510 20 13.9 6.1 0.05 1 GO:0009607 response to biotic stimulus 530 9 4.9 4.1 0.05 1 GO:0009611 response to wounding 233 5 2.1 2.9 0.06 1 GO:0043167 ion binding 1692 21 15.5 5.5 0.08 1 GO:0000267 cell fraction 510 8 4.7 3.3 0.09 1 GO:0005515 protein binding 2777 31 25.5 5.5 0.11 1 GO:0005886 plasma membrane 1090 14 10 4 0.12 1 GO:0005102 receptor binding 369 6 3.4 2.6 0.12 1 GO:0031090 organelle membrane 289 5 2.7 2.3 0.13 1 GO:0005624 membrane fraction 381 6 3.5 2.5 0.14 1 GO:0009653 morphogenesis 382 6 3.5 2.5 0.14 1 GO:0005737 cytoplasm 1829 21 16.8 4.2 0.15 1 GO:0046872 metal ion binding 1640 19 15.1 3.9 0.16 1 GO:0050791 regulation of physiological process 1755 20 16.1 3.9 0.17 1 GO:0044425 membrane part 1878 21 17.3 3.7 0.18 1 GO:0005856 cytoskeleton 427 6 3.9 2.1 0.2 1 GO:0051244 regulation of cellular physiological process 1697 19 15.6 3.4 0.2 1 GO:0016021 integral to membrane 1726 19 15.9 3.1 0.22 1 GO:0006950 response to stress 633 8 5.8 2.2 0.22 1 GO:0031224 intrinsic to membrane 1733 19 15.9 3.1 0.23 1 GO:0050794 regulation of cellular process 1843 20 16.9 3.1 0.23 1 GO:0006811 ion transport 361 5 3.3 1.7 0.24 1 GO:0044464 cell part 5317 52 48.9 3.1 0.25 1 GO:0048522 positive regulation of cellular process 383 5 3.5 1.5 0.28 1 GO:0048518 positive regulation of biological process 434 5 4 1 0.37 1 GO:0051234 establishment of localization 1412 14 13 1 0.42 1 GO:0051179 localization 1423 14 13.1 0.9 0.44 1 GO:0044422 organelle part 1033 10 9.5 0.5 0.48 1 GO:0044446 intracellular organelle part 1033 10 9.5 0.5 0.48 1 GO:0044444 cytoplasmic part 1290 12 11.9 0.1 0.53 1 GO:0007166 cell surface receptor linked signal transduction 642 6 5.9 0.1 0.55 1 GO:0044424 intracellular part 3635 33 33.4 -0.4 0.58 1 GO:0043232 intracellular non-membrane-bound organelle 701 6 6.4 -0.4 0.63 1 GO:0043228 non-membrane-bound organelle 701 6 6.4 -0.4 0.63 1 GO:0050875 cellular physiological process 4922 44 45.2 -1.2 0.67 1 GO:0016043 cell organization and biogenesis 869 7 8 -1 0.7 1 GO:0007165 signal transduction 1589 13 14.6 -1.6 0.73 1 GO:0044459 plasma membrane part 913 7 8.4 -1.4 0.75 1 GO:0005622 intracellular 3849 33 35.4 -2.4 0.75 1 GO:0007154 cell communication 1747 14 16.1 -2.1 0.76 1 GO:0004872 receptor activity 731 5 6.7 -1.7 0.81 1 GO:0006810 transport 1241 9 11.4 -2.4 0.83 1 GO:0043229 intracellular organelle 3131 25 28.8 -3.8 0.85 1 GO:0046914 transition metal ion binding 1033 7 9.5 -2.5 0.85 1 GO:0005887 integral to plasma membrane 784 5 7.2 -2.2 0.86 1 GO:0031226 intrinsic to plasma membrane 790 5 7.3 -2.3 0.86 1 GO:0016787 hydrolase activity 1014 6 9.3 -3.3 0.92 1 GO:0043231 intracellular membrane-bound organelle 2739 20 25.2 -5.2 0.92 1 GO:0043227 membrane-bound organelle 2740 20 25.2 -5.2 0.92 1 GO:0043283 biopolymer metabolism 1421 9 13.1 -4.1 0.93 1 GO:0043170 macromolecule metabolism 2169 14 19.9 -5.9 0.96 1 GO:0044260 cellular macromolecule metabolism 1438 8 13.2 -5.2 0.97 1 GO:0005634 nucleus 1880 11 17.3 -6.3 0.97 1 GO:0000166 nucleotide binding 1065 5 9.8 -4.8 0.98 1 GO:0044267 cellular protein metabolism 1409 7 12.9 -5.9 0.98 1 GO:0019538 protein metabolism 1556 8 14.3 -6.3 0.98 1 GO:0006139 "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" 1637 8 15 -7 0.99 1 GO:0044238 primary metabolism 3420 19 31.4 -12.4 1 1 GO:0008152 metabolism 3688 21 33.9 -12.9 1 1 GO:0044237 cellular metabolism 3468 19 31.9 -12.9 1 1