Table of parameters used in simulation and ODEs

Parameter

Description

A1

Monomer or assembly with one subunit

A0       

Monomer without binding capacity

Aj

Assembly consisting of j subunits

[Aj]

The concentration of an assembly with j subunits

N

The initial amount of monomers

L

The maximum number of subunits allowed in any filament

Ta

The average waiting time that two binding sites associate to form a bond. It is equal to ka in kinetics equations.

Td

The average waiting time that two binding sites disassociate to break a bond. It is equal to kd in kinetics equations.

T+

The average waiting time for a monomer to obtain the binding capacity. It is equal to + in kinetics equations.

T-

The average waiting time for a monomer to lose the binding capacity. It is equal to k- in kinetics equations.

 

 

 

Reaction equations:

 

 

    

 

 

ODEs based on reaction equations: