TOPIC 5
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Scale = 0 epochs = 1
1883-2002
TERM SCORE
activ 7060.30
protein 2460.87
enzym 1968.01
inhibit 1728.41
factor 1550.91
effect 1278.74
regul 1051.59
metabol 989.40
organ 932.39
condit 915.21
specif 907.23
growth 876.91
function 856.27
synthesi 850.51
increas 825.04


Scale = 1 epochs = 2
1883-1942
TERM SCORE
activ 1127.42
organ 829.88
condit 663.05
effect 477.77
power 456.46
factor 426.72
growth 376.36
protein 373.32
substanc 331.91
reaction 322.01
increas 312.92
caus 298.53
chang 296.88
action 274.84
act 238.74
1943-2002
TERM SCORE
activ 5932.88
protein 2087.55
enzym 1757.47
inhibit 1583.50
factor 1124.19
regul 972.92
effect 800.96
synthesi 798.75
specif 789.11
metabol 787.20
signal 731.72
induc 704.33
suggest 652.67
function 647.74
control 621.66


Scale = 2 epochs = 4
1883-1912
TERM SCORE
organ 716.20
condit 493.08
activ 400.48
power 366.33
caus 222.65
chang 201.05
act 177.81
effect 167.82
factor 150.12
process 129.98
increas 122.97
function 121.08
growth 115.16
action 96.43
product 91.12
1913-1942
TERM SCORE
activ 726.93
protein 328.83
effect 309.95
factor 276.60
substanc 263.18
growth 261.20
reaction 256.23
increas 189.95
action 178.41
condit 169.96
enzym 169.20
metabol 157.15
oxid 140.67
inhibit 116.76
organ 113.67
1943-1972
TERM SCORE
activ 2513.32
enzym 1146.68
inhibit 913.60
effect 496.00
metabol 467.92
synthesi 398.81
glucos 391.10
acid 387.72
phosphat 383.39
liver 365.63
action 302.79
reaction 293.37
substrat 268.40
concentr 268.00
system 259.08
1973-2002
TERM SCORE
activ 3419.56
protein 1935.84
factor 1015.55
regul 870.36
signal 705.10
inhibit 669.90
enzym 610.79
transcript 597.28
induc 586.13
function 549.29
kinas 548.17
specif 547.56
pathwai 486.55
mediat 467.34
suggest 447.88


Scale = 3 epochs = 8
1883-1897
TERM SCORE
organ 355.03
condit 327.88
power 314.76
activ 222.72
caus 172.69
act 130.16
chang 124.08
effect 111.78
process 88.35
increas 78.03
growth 71.30
function 63.21
factor 58.54
action 55.72
found 55.19
1898-1912
TERM SCORE
organ 361.17
activ 177.76
condit 165.20
factor 91.58
chang 76.97
function 57.86
effect 56.03
power 51.56
caus 49.96
act 47.64
increas 44.93
growth 43.86
process 41.63
action 40.70
product 37.95
1913-1927
TERM SCORE
activ 278.82
factor 115.03
substanc 114.86
reaction 113.78
effect 101.39
increas 99.22
condit 91.84
growth 84.55
protein 78.20
oxid 65.29
action 64.11
organ 63.03
sugar 62.50
result 53.52
product 53.35
1928-1942
TERM SCORE
activ 448.11
protein 250.62
effect 208.56
growth 176.64
factor 161.56
substanc 148.32
reaction 142.44
enzym 120.34
action 114.29
metabol 109.15
increas 90.72
inhibit 80.19
condit 78.12
oxid 75.38
yeast 74.14
1943-1957
TERM SCORE
activ 1068.78
enzym 521.46
inhibit 401.65
effect 261.23
metabol 232.42
glucos 221.80
phosphat 210.58
action 178.67
concentr 157.91
oxid 155.85
reaction 153.53
liver 140.68
substrat 136.76
acid 134.58
yeast 125.52
1958-1972
TERM SCORE
activ 1444.53
enzym 625.21
inhibit 511.94
synthesi 289.48
acid 253.13
metabol 235.50
effect 234.77
liver 224.94
phosphat 172.80
glucos 169.29
incorpor 161.46
system 152.48
inhibitor 152.43
specif 146.17
reaction 139.83
1973-1987
TERM SCORE
activ 1374.95
protein 558.77
enzym 358.39
factor 342.62
inhibit 291.72
regul 277.29
induc 257.57
synthesi 230.37
suggest 204.63
specif 202.54
metabol 200.96
control 200.02
product 185.16
effect 181.62
increas 173.09
1988-2002
TERM SCORE
activ 2044.61
protein 1377.06
factor 672.93
signal 622.59
regul 593.06
transcript 515.11
kinas 427.79
function 390.02
pathwai 378.83
inhibit 378.18
specif 345.01
requir 332.23
induc 328.55
mediat 321.20
express 281.80


Scale = 4 epochs = 16
1883-1889.5
TERM SCORE
power 222.97
condit 182.99
organ 146.84
activ 114.91
caus 100.18
act 78.02
chang 63.92
effect 54.18
process 37.25
increas 35.87
function 32.81
growth 32.43
factor 27.91
known 27.65
action 27.64
1890.5-1897
TERM SCORE
organ 208.18
condit 144.89
activ 107.80
power 91.79
caus 72.50
chang 60.15
effect 57.60
act 52.13
process 51.09
increas 42.15
growth 38.87
factor 30.62
function 30.40
found 28.19
action 28.08
1898-1904.5
TERM SCORE
organ 167.18
condit 79.89
activ 79.37
factor 41.59
chang 41.13
function 28.30
power 26.25
effect 25.71
act 24.96
caus 23.24
growth 23.16
increas 21.50
process 21.12
action 18.50
found 18.39
1905.5-1912
TERM SCORE
organ 193.98
activ 98.38
condit 85.30
factor 49.99
chang 35.83
effect 30.32
function 29.56
caus 26.72
power 25.31
increas 23.43
act 22.68
action 22.20
product 22.01
reaction 21.17
growth 20.69
1913-1919.5
TERM SCORE
activ 123.20
increas 59.32
factor 59.13
reaction 56.69
substanc 54.10
effect 50.27
condit 46.04
protein 44.41
growth 43.66
sugar 33.11
organ 31.44
oxid 31.17
result 29.56
action 28.67
power 27.69
1920.5-1927
TERM SCORE
activ 155.62
substanc 60.76
reaction 57.08
factor 55.90
effect 51.11
condit 45.79
growth 40.89
increas 39.89
action 35.44
oxid 34.11
protein 33.79
organ 31.58
concentr 30.14
sugar 29.39
product 27.05
1928-1934.5
TERM SCORE
activ 181.07
effect 102.45
growth 93.88
factor 92.66
substanc 76.02
reaction 66.74
protein 59.82
increas 52.93
action 52.75
metabol 51.41
enzym 46.60
condit 38.61
oxid 31.41
tissu 29.52
function 29.52
1935.5-1942
TERM SCORE
activ 267.03
protein 190.79
effect 106.10
growth 82.76
reaction 75.70
enzym 73.73
substanc 72.29
factor 68.89
action 61.54
metabol 57.73
inhibit 50.74
yeast 47.10
oxid 43.96
concentr 40.29
condit 39.51
1943-1949.5
TERM SCORE
activ 465.62
enzym 198.24
inhibit 183.60
effect 141.25
concentr 96.98
action 95.51
metabol 84.88
glucos 79.93
phosphat 62.74
growth 61.84
found 61.47
acid 58.42
reaction 57.53
yeast 56.96
result 56.71
1950.5-1957
TERM SCORE
activ 603.15
enzym 323.22
inhibit 218.05
phosphat 147.84
metabol 147.53
glucos 141.86
effect 119.98
oxid 102.78
liver 101.91
reaction 96.00
reduc 88.61
action 83.15
substrat 80.47
acid 76.16
system 70.11
1958-1964.5
TERM SCORE
activ 756.29
enzym 303.46
inhibit 276.79
metabol 137.45
acid 137.40
effect 132.89
synthesi 119.69
glucos 87.38
reaction 83.30
liver 83.14
inhibitor 82.85
system 82.72
format 80.87
incorpor 78.93
specif 78.72
1965.5-1972
TERM SCORE
activ 688.24
enzym 321.75
inhibit 235.15
synthesi 169.79
liver 141.79
acid 115.72
effect 101.87
metabol 98.04
phosphat 96.00
incorpor 82.53
glucos 81.91
tissu 78.61
assai 71.22
protein 70.79
system 69.75
1973-1979.5
TERM SCORE
activ 606.76
enzym 156.80
inhibit 132.14
protein 124.27
induc 123.64
synthesi 122.07
factor 113.72
control 112.00
regul 104.30
metabol 102.89
effect 91.86
increas 91.63
suggest 85.65
specif 84.84
system 70.84
1980.5-1987
TERM SCORE
activ 768.18
protein 434.49
factor 228.90
enzym 201.58
regul 172.99
inhibit 159.57
induc 133.92
growth 129.35
transform 127.43
product 123.87
suggest 118.98
specif 117.69
synthesi 108.29
enhanc 103.61
function 101.60
1988-1994.5
TERM SCORE
activ 1057.46
protein 828.60
factor 404.29
transcript 293.16
regul 262.45
signal 214.25
function 209.66
inhibit 204.64
kinas 200.78
specif 193.87
requir 162.40
promot 154.44
enzym 149.40
express 146.64
suggest 143.39
1995.5-2002
TERM SCORE
activ 987.14
protein 548.46
signal 408.33
regul 330.61
factor 268.63
pathwai 240.21
kinas 227.00
transcript 221.95
edu 215.63
induc 192.47
mediat 181.40
function 180.36
inhibit 173.54
sciencemag 171.95
requir 169.82


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