0. DOCID:26302 SCORE: 0.00218271244943124
DOCNO: 11114421
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: prevention & control
QUALIFIER: prevention & control
QUALIFIER: immunology
AUTHOR: C Hatzifoti C
AUTHOR: B W Wren BW
AUTHOR: W J Morrow WJ
AFFILIATION: Dept of Immunology, St Bartholomew's and the Royal London School of Medicine and Dentistry, 38 Little Britain, EC1A 7BE, London, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Immunology today.
COUNTRY: ENGLAND
TITLE: Helicobacter pylori vaccine strategies--triggering a gut reaction.
PUBDATE: 20001201
Helicobacter pylori causes peptic ulcer disease and some forms of gastric cancer; it is one of the most common chronic bacterial infections of humans. Although several prototype protein-based vaccines have shown promising results, they have not cleared infection and/or prevented reinfection. Nucleic acid vaccination offers a useful alternative to protein immunization, especially now that two complete H. pylori genome sequences are available, and facilitates the selection of antigenic targets.

1. DOCID:27358 SCORE: 0.00213795409848736
DOCNO: 10996485
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: toxicity
QUALIFIER: physiology
AUTHOR: L Brunetti L
AUTHOR: G Orlando G
AUTHOR: B Michelotto B
AUTHOR: L Recinella L
AUTHOR: E Ragazzoni E
AUTHOR: M Vacca M
AFFILIATION: Department of Drug Sciences, G. D'Annunzio University, via dei Vestini, 66013, Chieti, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Toxicology letters.
COUNTRY: NETHERLANDS
TITLE: A possible prolactin-related adverse effect of certain antineoplastic anthracyclines.
PUBDATE: 20000801
Nonhormonal antineoplastic therapy can affect the endocrine system with consequent effects on the growth of hormone-sensitive tumors. Amongst anthracycline antibiotics, we have found daunorubicin and epirubicin able to acutely stimulate prolactin (PRL) secretion both in vivo, in the rat, and in vitro, from rat anterior pituitary cell cultures. Despite a similar structure, doxorubicin showed no such activity. Considering the possible role of PRL in breast cancer cell proliferation, the effects of certain anthracyclines might be viewed as an adverse drug reaction involving the anterior pituitary gland.

2. DOCID:27410 SCORE: 0.00213792431527057
DOCNO: 9560532
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: M Kanazawa M
AUTHOR: T Maruyama T
AUTHOR: T Suzuki T
AUTHOR: K Soejima K
AUTHOR: M Hayashi M
AUTHOR: K Yamazaki K
AFFILIATION: Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.
PUBTYPE: Case Reports
PUBTYPE: Clinical Conference
PUBTYPE: Journal Article
JOURNALTITLE: The Keio journal of medicine.
COUNTRY: JAPAN
TITLE: A case of rapidly progressing small cell lung cancer incidentally found during the course of renal failure.
PUBDATE: 19980301
A 65-year-old man with rapidly progressing small cell lung cancer found in the course of renal failure is reported. The patient had a medical history of hypertension, diabetes mellitus, and cardiovascular disease. Hemodialysis was introduced following renal failure, but pneumonia resulted in a transient exacerbation and his complaint of general fatigue did not improve. Examination for the fatigue revealed no apparent abnormalities. Three months later, he died of small cell lung cancer.

3. DOCID:27414 SCORE: 0.00213792207585347
DOCNO: 11754419
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: A Raj A
AUTHOR: R Bendon R
AUTHOR: T Moriarty T
AUTHOR: C Suarez C
AUTHOR: S Bertolone S
AFFILIATION: Department of Pediatric Hematology/Oncology, University of Louisville, Louisville, Kentucky 40202, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of hematology.
COUNTRY: United States
TITLE: Langerhans cell histiocytosis following childhood acute lymphoblastic leukemia.
PUBDATE: 20011201
Langerhans cell histiocytosis (LCH) is a clonal proliferation of Langerhans cells of unknown etiology that results in a range of clinical manifestations. LCH has been known to be associated with a variety of malignant diseases. A 7-year-old boy was treated for standard-risk acute lymphoblastic leukemia (ALL) at age 2 years, on a Children's Cancer Group chemotherapy protocol for 3 years and developed LCH 2 years after completion of chemotherapy. The case and a review of literature on the association of LCH and ALL are presented.

4. DOCID:27921 SCORE: 0.00212305304093666
DOCNO: 10859696
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: pharmacology
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: B R Lackey BR
AUTHOR: S L Gray SL
AUTHOR: D M Henricks DM
AFFILIATION: Endocrine Physiology Laboratory, Department of Animal and Veterinary Science, Clemson University, South Carolina, USA. blackey@clemson.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Medical hypotheses.
COUNTRY: SCOTLAND
TITLE: Synergistic approach to cancer therapy: exploiting interactions between anti-estrogens, retinoids, monoterpenes and tyrosine kinase inhibitors.
PUBDATE: 20000501
Non-responsiveness and toxicity are large problems encountered during cancer treatment. Utilization of compounds that synergize should increase treatment efficacy while avoiding problems of toxicity. This review explores interactions between classes of compounds, including anti-estrogens, retinoids, monoterpenes and tyrosine kinase inhibitors, that are effective independent, and how their synergistic interaction could be exploited in cancer treatment. The effects of these compounds on insulin-like growth factors (IGF) and transforming-growth factor-beta (TGF-beta) will also be examined.

5. DOCID:27210 SCORE: 0.00203403887582258
DOCNO: 9795581
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
AUTHOR: S G Von Essen SG
AUTHOR: S A McCurdy SA
AFFILIATION: Department of Internal Medicine, University of Nebraska Medical Center, Omaha 68198-5300, USA. svonesse@unmc.edu
PUBTYPE: Journal Article
JOURNALTITLE: The Western journal of medicine.
COUNTRY: UNITED STATES
TITLE: Health and safety risks in production agriculture.
PUBDATE: 19981001
Production agriculture is associated with a variety of occupational illnesses and injuries. Agricultural workers are at higher risk of death or disabling injury than most other workers. Traumatic injury commonly occurs from working with machinery or animals. Respiratory illness and health problems from exposures to farm chemicals are major concerns, and dermatoses, hearing loss, certain cancers, and zoonotic infections are important problems. Innovative means of encouraging safe work practices are being developed. Efforts are being made to reach all groups of farmworkers, including migrant and seasonal workers, farm youth, and older farmers.

6. DOCID:26247 SCORE: 0.00186942464359281
DOCNO: 10554946
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Estrogen Receptor Modulators
DESCRIPTOR: Isoflavones
DESCRIPTOR: Selective Estrogen Receptor Modulators
QUALIFIER: drug therapy
AUTHOR: A Evans A
AUTHOR: B Vollenhoven B
AUTHOR: D Healy D
AFFILIATION: Monash University Department of Obstetrics and Gynaecology, Monash Medical Centre, Victoria.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Australian & New Zealand journal of obstetrics & gynaecology.
COUNTRY: AUSTRALIA
TITLE: Modern antioestrogens and the coming revolution in women's health care.
PUBDATE: 19990801
This review will focus on antioestrogens and selective oestrogen receptor modulators (SERMS). The more traditional SERMS, clomiphene citrate and tamoxifen, will be reviewed along with such modern drugs as raloxifene and faslodex, with emphasis upon their actions on breast, uterus, bone and lipids. The future potential of these medications, in the management of oestrogen-dependent gynaecological conditions such as endometriosis, dysfunctional uterine bleeding, fibroids and breast cancer will be discussed.

7. DOCID:27490 SCORE: 0.00183216100642079
DOCNO: 10690040
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: nursing
QUALIFIER: nursing
QUALIFIER: surgery
QUALIFIER: organization & administration
AUTHOR: M L Sladek ML
AUTHOR: K K Swenson KK
AUTHOR: L J Ritz LJ
AUTHOR: L M Schroeder LM
AFFILIATION: Institute for Research and Education, HealthSystem Minnesota, Minneapolis, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical journal of oncology nursing.
COUNTRY: UNITED STATES
TITLE: A critical pathway for patients undergoing one-day breast cancer surgery.
PUBDATE: 19990701
As the trend of surgical procedures shifting from inpatient to outpatient settings continues, outpatient-focused standardized care processes will become more of a necessity. A multidisciplinary critical pathway (CP) for breast cancer surgery can assist care providers in meeting patients' educational and psychosocial needs. The CP document discussed in this article takes into account the expedient nature of outpatient surgery and spans the continuum of care from the surgical clinic to the postoperative homecare visit. Integrating homecare nursing improves the quality and consistency of care.

8. DOCID:27889 SCORE: 0.00182725949459236
DOCNO: 11576702
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Patient Selection
QUALIFIER: surgery
AUTHOR: M Semik M
AUTHOR: C Schmid C
AUTHOR: F Trösch F
AUTHOR: P Broermann P
AUTHOR: H H Scheld HH
AFFILIATION: Department of Cardiothoracic Surgery, University Hospital Muenster, Albert-Schweitzer Strasse 33, D-48129, Muenster, Germany. michael.semik@thgms.uni-muenster.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Lung cancer (Amsterdam, Netherlands)
COUNTRY: Ireland
TITLE: Lung cancer surgery--preoperative risk assessment and patient selection.
PUBDATE: 20010901
Lung resection remains the therapy of choice offering the greatest potential for cure in non spread lung cancer. As these procedures have a significant rate of cardiopulmonary complications, risk assessment and evaluation of functional operability is essential for successful resectional surgery. The most valuable parameters for evaluation of lung function and risk assessment are FEV1, DLCO and VO2max as well as the calculation of predicted postoperative lung function. With preoperative preparatory physical therapy and treatment of comorbidities, also marginal patients may become operable for resectional surgery.

9. DOCID:27967 SCORE: 0.0018272129180315
DOCNO: 9793012
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: therapy
AUTHOR: P Puri P
AUTHOR: S K Datta SK
AFFILIATION: Department of Ophthalmology, Hull Royal Infirmary, UK.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer care.
COUNTRY: ENGLAND
TITLE: Management of choroidal metastasis: a report.
PUBDATE: 19980901
Cancers metastatic to the eye are the most common intraocular malignancy, the choroid being the most common site of affection. Breast and lung cancers are the two most common malignancies metastatic to the eye. Patients usually present with diminished visual acuity of field loss. Management of these cases is very gratifying with a large majority of patients showing resolution and maintenance of useful vision in the involved eye. This communication presents our experience in management of a case of choroidal metastasis from a breast primary. A combination of radiotherapy and chemotherapy lead to complete resolution of the lesion with no recurrences in a follow-up of over 6 months.

10. DOCID:27540 SCORE: 0.00179145013997881
DOCNO: 11444172
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Drosophila Proteins
DESCRIPTOR: Genetic Markers
QUALIFIER: genetics
AUTHOR: E Puxeddu E
AUTHOR: J A Fagin JA
AFFILIATION: Division of Endocrinology and Metabolism, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Endocrinology and metabolism clinics of North America.
COUNTRY: United States
TITLE: Genetic markers in thyroid neoplasia.
PUBDATE: 20010601
Cancer is a disease of genes. Detection of genetic abnormalities associated with cancers of various cell types can now be used for genetic counseling, diagnosis or treatment selection. In the case of thyroid cancer, genetic testing for mutations of the RET oncogene has had a profound effect on the management of medullary thyroid carcinomas. There is also considerable information on the genetic changes associated with development and progression of cancers of thyroid follicular cells, although these have not yet proven to be of practical value for clinical diagnosis or to guide prognosis and therapy.

11. DOCID:27699 SCORE: 0.00176070923983253
DOCNO: 10791149
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: African Americans
DESCRIPTOR: Dermatology
DESCRIPTOR: Health Services Accessibility
DESCRIPTOR: Minority Groups
AUTHOR: A J McMichael AJ
AUTHOR: S Jackson S
AFFILIATION: Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Dermatologic clinics.
COUNTRY: UNITED STATES
TITLE: Issues in dermatologic health care delivery in minority populations.
PUBDATE: 20000401
It is well known that African Americans are at low risk for one of the most serious diagnoses in dermatology--skin cancer. A consequence of this lower cancer risk has been an undervaluing of the importance of appropriate dermatologic care in this population. In fact, there are many other skin diseases and disorders that not only cause significant morbidity among this population but also emotional and psychological sequelae. This article examines barriers and challenges to providing dermatologic care among African Americans and provides recommendations and suggestions for improving care delivery in this population.

12. DOCID:24401 SCORE: 0.00173948439851721
DOCNO: 11050427
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Transcription, Genetic
QUALIFIER: genetics
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: A N Monteiro AN
AFFILIATION: Dept of Cell Biology, Weill Medical College of Cornell University, New York, NY 10021, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Trends in biochemical sciences.
COUNTRY: ENGLAND
TITLE: BRCA1: exploring the links to transcription.
PUBDATE: 20001001
Progress on determining the function of the breast and ovarian cancer susceptibility gene BRCA1 suggests it might be involved in two fundamental cellular processes: DNA repair and transcriptional regulation. Recent developments indicate that BRCA1 is a multifunctional protein, and disruption of its transcriptional activity could be crucial for tumor development.

13. DOCID:26070 SCORE: 0.00172935625206799
DOCNO: 10525638
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusions, Intra-Arterial
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
AUTHOR: J Görich J
AUTHOR: R Tomczak R
AUTHOR: A Gabelmann A
AUTHOR: C Wisianowski C
AUTHOR: S Krämer S
AFFILIATION: Abteilung für Röntgendiagnostik der Universitätsklinik Ulm.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Der Radiologe.
COUNTRY: GERMANY
TITLE: [Intraarterial chemotherapy in cases of breast cancer]
PUBDATE: 19990901
A general review of the results and technique of intraarterial chemotherapy in cases of breast cancer is given. The remission rate for untreated primary tumors is nearly 100%, for completely treated local relapses approximately 70%. The complication rate is quite low using an intraarterial well-tolerated cytostatic agent such as mitoxantrone. However, thromboembolism of the vertebral artery facing the internal mammary artery may occur. The indication for intraarterial chemotherapy should always be set by an interdisciplinary board.

14. DOCID:26077 SCORE: 0.00169881473882339
DOCNO: 10448696
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymphatic Metastasis
QUALIFIER: pathology
AUTHOR: E C Grendys EC
AUTHOR: C Salud C
AUTHOR: J K Durfee JK
AUTHOR: J V Fiorica JV
AFFILIATION: Department of Gynecologic Oncology, University of South Florida School of Medicine, Tampa, USA. Grendyec@Moffit.USF.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Lymphatic mapping in gynecologic malignancies.
PUBDATE: 19990701
Gynecologic malignancies account for 15% of all cancer diagnosis in women. Primary lymphatic spread is well recognized in vulvar, cervical, uterine, and ovarian carcinomas. Vulvar carcinoma spreads locally to the inguinofemoral lymph nodes in a relatively predictable fashion similar to the local spread of breast carcinoma. Lymphatic mapping using radioactive colloid should provide adequate means to sample these nodal basins while attempting to reduce postoperative morbidity. Methods of vulvar lymphoscintigraphy are described.