0. DOCID:14674 SCORE: 0.00253279603876608
DOCNO: 3175558
AUTHOR: C E Minder CE
AUTHOR: J P Vader JP
AFFILIATION: Department of Social and Preventive Medicine, University of Berne, Switzerland.
PUBTYPE: Journal Article
JOURNALTITLE: Scandinavian journal of work, environment & health.
COUNTRY: FINLAND
TITLE: Malignant pleural mesothelioma among Swiss furniture workers. A new high-risk group.
PUBDATE: 19880801
Within the framework of a research project concerning occupational mortality, attention was drawn to a highly significant standardized mortality ratio for mesothelioma among furniture workers. From information drawn from the mortality records for the years 1979-1985 and from the 1980 national census, the number of pleural mesotheliomas among this occupational group was examined. The expected number of deaths from pleural mesothelioma among Swiss furniture workers for this period was 4.4; the observed number was 12. This finding indicates a 2.7-fold relative risk (P = 0.004) for death due to these cancers among Swiss furniture workers.

1. DOCID:15317 SCORE: 0.0021656532228423
DOCNO: 3798569
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: M Reinfuss M
AUTHOR: S Korzeniowski S
PUBTYPE: Journal Article
JOURNALTITLE: Tumori.
COUNTRY: ITALY
TITLE: Results of combined radiotherapy and multidrug chemotherapy in advanced squamous cell cancer of the head and neck.
PUBDATE: 19861001
Treatment results of combined radiotherapy and polychemotherapy in a group of 38 patients with advanced squamous cell of the head and neck cancer are presented. The radio-chemotherapy schedule included 60Co irradiation with 20 Gy in 10 fractions over two weeks followed by multidrug chemotherapy with vincristine, bleomycin, methotrexate and leucovorin. Three series of radio-chemotherapy were given. In 14 patients the total dose of irradiation was increased to 70-105 Gy. The probabilities of overall and symptom-free survival at 2 years were 32% and 20%, respectively. Treatment results correlated with stage of the disease. Patients who received higher doses of radiation seemed to have better chances of symptom-free survival.

2. DOCID:15391 SCORE: 0.00216563295465211
DOCNO: 2820741
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: D A Morgan DA
AUTHOR: D Gilson D
AUTHOR: J Fletcher J
AFFILIATION: Hogarth Centre of Radiotherapy and Oncology, General Hospital, Nottingham, England.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Vincristine and etoposide: an effective chemotherapy regimen with reduced toxicity in extensive small-cell lung cancer.
PUBDATE: 19870601
Chemotherapy prolongs survival of patients with small-cell lung cancer, but very few are cured, and the treatment is unpleasant. Thirty patients, 28 with advanced disease, were treated with etoposide 250 mg/m2 orally, daily for 5 days, plus vincristine 2 mg intravenously on the first day, the cycle being repeated 3-weekly, to a maximum of 6. There was a response rate of 70%, a median survival of 249 days, and an 11% 2-year survival. Symptomatic side-effects were less pronounced than with most other regimens of comparable efficacy.

3. DOCID:13409 SCORE: 0.00214128459715854
DOCNO: 3733006
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H Kerner H
AUTHOR: C Lichtig C
PUBTYPE: Journal Article
JOURNALTITLE: Histopathology.
COUNTRY: ENGLAND
TITLE: Lobular cancerization: incidence and differential diagnosis with lobular carcinoma in situ of breast.
PUBDATE: 19860601
A series of 120 breast biopsies and mastectomy specimens originally diagnosed as carcinoma was reviewed in order to emphasize the differences between lobular carcinoma in situ and cancerization of lobules. Criteria for differential diagnosis between the two types of lobular lesion are proposed. In the reviewed material 15 (12.5%) cases of lobular carcinoma in situ and 64 (53.3%) of lobular cancerization were found. The carcinoma in situ usually co-existed with other types of breast carcinoma, such as intraductal carcinoma, cancerization and invasive carcinoma of different types.

4. DOCID:13298 SCORE: 0.00187043416909823
DOCNO: 3783950
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: T Iwanaga T
AUTHOR: H Furukawa H
AUTHOR: M Hiratsuka M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Surgical treatment of intermediate-stage gastric cancer]
PUBDATE: 19860801
Gastric cancers for which either the invasion depth of the stomach wall layers is moderate or the extent of lymph node metastasis is moderate were defined as carcinomas of intermediate-stage. In consideration of the clinico-pathological characteristics of these intermediate-stage gastric cancers, the therapeutic methods for the cancers were studied. It was concluded that since intermediate-stage gastric cancer is a kind of advanced cancers, the most desirable surgical approach will be a radical surgical operation and an adequate adjuvant therapy.

5. DOCID:13597 SCORE: 0.0017067063729131
DOCNO: 3709599
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: M L Slevin ML
AUTHOR: V J Harvey VJ
AUTHOR: R J Osborne RJ
AUTHOR: J H Shepherd JH
AUTHOR: C J Williams CJ
AUTHOR: G M Mead GM
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: A phase II study of tamoxifen in ovarian cancer.
PUBDATE: 19860301
A phase II study of tamoxifen was conducted in 22 patients with stage III and IV ovarian cancer who had failed chemotherapy and who had evaluable disease. Tamoxifen was administered at a dose of 20 mg twice daily continuously until evidence of progression. Twenty-one patients had progression of disease within 3 months and one patient had stable disease for 6 months. There were no objective responses to this treatment.

6. DOCID:15159 SCORE: 0.00168833855696417
DOCNO: 2519448
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Indians, South American
QUALIFIER: epidemiology
AUTHOR: I Roa I
AUTHOR: J C Araya JC
AUTHOR: X de Aretxabala X
AUTHOR: C Salinas C
AUTHOR: I Wistuba I
PUBTYPE: Journal Article
JOURNALTITLE: Revista médica de Chile.
COUNTRY: CHILE
TITLE: [Gallbladder pathology in Temuco, IX Region]
PUBDATE: 19890801
We reviewed the histological (light microscopy) findings in 1553 biopsies obtained after surgery for gallbladder disease and correlated these with demographic characteristics of patients. Cancer of the gallbladder was present in 6.1%. Women prevailed in all age and disease groups, especially in mapuches (11:1). Both for neoplastic and nonneoplastic disease the proportion of patients with mapuche surnames was lower than expected for the population in the area. 52% of neoplastic lesions were not macroscopically apparent. Seven tumors involved only the mucous layer and 2 were intraepithelial. Only 2 tumors were well differentiated. The liver was the organ most frequently invaded by gallbladder cancer.

7. DOCID:13672 SCORE: 0.00164935155406911
DOCNO: 2525739
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: S Adjiman S
AUTHOR: M Zerbib M
AUTHOR: T Flam T
AUTHOR: S Desligneres S
AUTHOR: B Debré B
AUTHOR: A Steg A
AFFILIATION: Clinique urologique, Hôpital Cochin, Paris.
PUBTYPE: Journal Article
JOURNALTITLE: Presse médicale (Paris, France : 1983)
COUNTRY: FRANCE
TITLE: [Treatment of epidermoid carcinoma of the penis]
PUBDATE: 19890601
Epidermoid carcinoma of the penis is a rare type of cancer. Treatment of the primary lesion consists of amputation, although curietherapy can be effective in some cases as a conservative treatment. The prognosis is determined by the presence of absence of lymph node invasion, but the therapeutic strategy to be used when invaded lymph nodes are present remains controversial. Lymph node dissection is the only effective treatment of metastatic adenopathy, but its high morbidity rate limits its indications.

8. DOCID:14300 SCORE: 0.0016290080548826
DOCNO: 3694017
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: A J Greenstein AJ
AUTHOR: R Gennuso R
AUTHOR: D B Sachar DB
AUTHOR: A H Aufses AH
AFFILIATION: Department of Surgery, Mount Sinai School of Medicine of the City University of New York, New York.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: International journal of colorectal disease.
COUNTRY: GERMANY, WEST
TITLE: Free perforation due to cancer in Crohn's disease.
PUBDATE: 19871101
Free perforation of cancer in Crohn's disease is exceedingly rare. Three cases were found among 1010 patients admitted to Mount Sinai Hospital between 1960 and 1980. Free perforation of cancer occurs late in the course of Crohn's disease between the second and third decades of disease, whereas spontaneous free perforation usually occurs within the first 5 years. Cancer-related perforation is associated with weight loss, mass and fistula, and carries a poor prognosis.

9. DOCID:14893 SCORE: 0.00162288147075105
DOCNO: 3784820
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: V G Andreev VG
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Combination treatment of recurring laryngeal cancer]
PUBDATE: 19861101
The results of treatment of 192 patients with recurring and incurable laryngeal cancer after a previous course of radiotherapy were studied. Of the total number of patients 95 were treated by surgery only and 97 received a preoperative course of intensive radiotherapy. The study has shown that the irradiation of recurring and incurable by radiotherapy tumors of the larynx at a dose of 6 Gy on the eve and on the day of operation (a summary focal dose of 12 Gy, DMF--37 units) permits an increase of the index of uncomplicated healing of the laryngeal wound from 68.4 up to 86%; simultaneously the 3-year recurrence and metastasis-free survival rates increase from 47.8 up to 81.4%.

10. DOCID:15002 SCORE: 0.00160051240353141
DOCNO: 3231739
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Health Services Needs and Demand
DESCRIPTOR: Health Services Research
QUALIFIER: trends
AUTHOR: S Johansen S
AUTHOR: S Bowles S
AUTHOR: G Haney G
AFFILIATION: Columbia University School of Public Health, New York, NY.
PUBTYPE: Journal Article
JOURNALTITLE: Research in nursing & health.
COUNTRY: UNITED STATES
TITLE: A model for forecasting intermittent skilled home nursing needs.
PUBDATE: 19881201
The problem of forecasting the need and the cost for post-discharge skilled home nursing services is addressed by a simple statistical model. The model, assumptions, and simple calculations are described. Use of the model is illustrated with 7598 cancer patients and 2337 myocardial infarction patients. Simulation of the impact of changes in the health care delivery system toward greater and lesser severity of hospitalized patients is carried out. Two key projections illustrating the model's output are the number of patients with these diseases who will need care and the cost of that care.

11. DOCID:15330 SCORE: 0.0015976585968171
DOCNO: 2654502
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunotherapy
DESCRIPTOR: Lymphokines
QUALIFIER: therapeutic use
QUALIFIER: immunology
QUALIFIER: therapy
AUTHOR: C M van Haelst-Pisani CM
AUTHOR: R J Pisani RJ
AUTHOR: J S Kovach JS
AFFILIATION: Department of Oncology, Mayo Clinic, Rochester, MN 55905.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Mayo Clinic proceedings. Mayo Clinic.
COUNTRY: UNITED STATES
TITLE: Cancer immunotherapy: current status of treatment with interleukin 2 and lymphokine-activated killer cells.
PUBDATE: 19890401
In recent years, the medical community has witnessed a growing interest in the use of adoptive immunotherapy in patients with malignant lesions refractory to standard treatments. Systemic administration of interleukin 2, in combination with the adoptive transfer of a patient's own activated immune cells, has resulted in objective regression of several types of advanced cancers. Pronounced regression of tumor has also been observed with use of systemic interleukin 2 alone. This ability to augment the immune defense system of the host against cancer has stimulated intense clinical and laboratory investigations.

12. DOCID:15340 SCORE: 0.00159119142533901
DOCNO: 2851491
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: methods
AUTHOR: J W Fountain JW
AUTHOR: W K Lockwood WK
AUTHOR: F S Collins FS
AFFILIATION: Howard Hughes Medical Institute, University of Michigan, Ann Arbor 48109.
PUBTYPE: Journal Article
JOURNALTITLE: Gene.
COUNTRY: NETHERLANDS
TITLE: Transfection of primary human skin fibroblasts by electroporation.
PUBDATE: 19880801
Primary human skin fibroblasts are an accessible source of phenotypically and karyotypically normal human cells, but are difficult to transfect with exogenous DNA. Here we demonstrate that both transient expression and stable transformation can be carried out by the method of electroporation. Highly efficient transient chloramphenicol acetyltransferase expression was shown after transfection with plasmid pRSVCAT. Stable transformation of human skin fibroblasts to G418 resistance was obtained after electroporation with neo-containing plasmids at an efficiency of approximately 1.4 x 10(-5)/micrograms DNA. The ability to easily transfect these cells with exogenous DNA may have important applications in the study of human genetic diseases and cancer.

13. DOCID:15422 SCORE: 0.0015909758452283
DOCNO: 3135275
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Enteral Nutrition
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: M Keymling M
AUTHOR: H J Lübke HJ
AUTHOR: W Wörner W
AFFILIATION: Medizinische Klinik, Kreiskrankenhaus Hersfeld.
PUBTYPE: Journal Article
JOURNALTITLE: Infusionstherapie (Basel, Switzerland)
COUNTRY: SWITZERLAND
TITLE: [Chemotherapy and enteral nutrition in stomach cancer]
PUBDATE: 19880401
Malnutrition is a frequent problem in cancer patients. About 45% of them lose more than 10% of their original weight at the various stages of their disease. The importance of nutritional support was repeatedly pointed out. In our study, 10 patients with metastatic gastrointestinal cancer received a combination treatment of long-term tube feeding with elemental diets and chemotherapy. The initially low Karnofsky index improved significantly. The results of the chemotherapy are comparable to those of 9 international studies between 1976 and 1979, using a comparable therapeutic scheme in patients with initially higher Karnofsky index. Ingestion-dependent abdominal pain disappeared in responders and non-responders during the time of tube feeding.

14. DOCID:14403 SCORE: 0.00153490662926626
DOCNO: 3011052
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: D Serwadda D
AUTHOR: W Carswell W
AUTHOR: W O Ayuko WO
AUTHOR: W Wamukota W
AUTHOR: P Madda P
AUTHOR: R G Downing RG
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Further experience with Kaposi's sarcoma in Uganda.
PUBDATE: 19860401
Four Ugandan patients (1 women, 3 men) with generalized Kaposi's sarcoma (KS) were seen in the Uganda Cancer Institute between October 1983 and December 1984. They presented with generalized lymphadenopathy, plaques/nodules on the body, general swelling of the head, oral and visceral involvement and respiratory distress. Initial responses to adriamycin as a single or a combination chemotherapy of actinomycin D, vincristine, adriamycin and imidazole carboxamide appeared to be favourable but no sustained response was obtained. Serological tests for human T-lymphotropic virus (HTLV-II) antibodies were positive in all 4 cases.