0. DOCID:23267 SCORE: 0.00256685937500105
DOCNO: 7658533
AUTHOR: K J Ho KJ
AFFILIATION: Department of Laboratory Medicine, National Taiwan University, College of Medicine, Taipei.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy.
PUBDATE: 19951001
PURPOSE: The usefulness of urinary beta-glucuronidase in screening and followup of urinary tract malignancy was tested. MATERIALS AND METHODS: The activity and concentration of urinary beta-glucuronidase were determined in 80 healthy subjects, 113 urology patients with no cancer, and 60 with transitional cell and 23 with renal cell carcinoma. Patients with cancer were followed for 3 to 33 weeks. RESULTS: The enzyme activity and concentration were significantly greater in the cancer group, including residual tumor or recurrence after therapy, than in the controls with excellent discrimination. CONCLUSIONS: Urinary beta-glucuronidase was indeed useful in screening and followup of urinary tract malignancy.


1. DOCID:17324 SCORE: 0.00235588092909713
DOCNO: 8390708
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: M D Isla Casado MD
AUTHOR: R Escó Barón R
AUTHOR: A Castillo Ramírez A
AFFILIATION: Servicio de Oncología Radioterápica, Hospital Clínico Universitario de Zaragoza.
PUBTYPE: Journal Article
JOURNALTITLE: Revista clínica española.
COUNTRY: SPAIN
TITLE: [Survival analysis in lung cancer treated with radiotherapy]
PUBDATE: 19930501
From June-78 to December-89, 300 patients with histologic diagnosis of non-small cell lung cancer were treated with radiotherapy by different indications: radical intention, post-chemotherapy, palliative intention, symptomatic and postsurgery. It was employed an electrons lineal accelerator principally, and for symptomatic radiotherapy treatment was used telegammatherapy by cobalt-60. It was treated an retrospective non comparative study which it has analyzed the survival of the different radiotherapy indications.


2. DOCID:30502 SCORE: 0.00234839009628168
DOCNO: 15678907
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: etiology
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: Hirokazu Taniguchi H
AUTHOR: Minehiko Inomata M
AUTHOR: Hitoshi Abo H
AUTHOR: Hideki Miyazawa H
AUTHOR: Hirofumi Noto H
AUTHOR: Saburo Izumi S
AFFILIATION: Department of Internal Medicine, Toyama Central Prefectural Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society.
COUNTRY: Japan
TITLE: [Central diabetes insipidus caused by pituitary metastasis of lung cancer]
PUBDATE: 20041201
A 53-year-old man admitted for thirst, polyposia, and polyuria. Large cell lung cancer T3N2M1 (Stage IV), and central diabetes insipidus caused by pituitary metastasis of lung cancer, were diagnosed. We gave him desmopressin acetate, and chemotherapy with paclitaxel and carboplatin. But pituitary metastasis increased and invaded the hypothalamus. After irradiation of the pituitary and hypothalamus, metastatic focus diminished and desmopressin acetate was tapered.


3. DOCID:30153 SCORE: 0.00234588102541428
DOCNO: 15830146
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: secondary
QUALIFIER: drug therapy
QUALIFIER: pathology
QUALIFIER: therapeutic use
AUTHOR: Mark Clemons M
AUTHOR: Sunil Verma S
AFFILIATION: Division of Medical Oncology, Toronto-Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. mark.clemons@sw.ca
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Breast cancer research and treatment.
COUNTRY: Netherlands
TITLE: Should oral bisphosphonates be standard of care in women with early breast cancer?
PUBDATE: 20050401
There is increasing evidence that oral clodronate has important clinical benefits in early breast cancer. Longer-term follow-up data from two out of three randomized studies have shown that adjuvant clodronate improves survival. This article outlines the results of these studies and discusses the potential role for other bisphosphonates, such as ibandronate and zoledronic acid, in the adjuvant treatment of breast cancer.


4. DOCID:30214 SCORE: 0.00234587826450638
DOCNO: 15906369
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Apoptosis
DESCRIPTOR: Neovascularization, Pathologic
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: Jannis Kountouras J
AUTHOR: Christos Zavos C
AUTHOR: Dimitrios Chatzopoulos D
AFFILIATION: Department of Medicine, Second Medical Clinic, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece. jannis@med.auth.gr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: United States
TITLE: Apoptotic and anti-angiogenic strategies in liver and gastrointestinal malignancies.
PUBDATE: 20050601
Inappropriate suppression of apoptosis is strongly implicated in tumorigenesis. Tumor development is heralded by the mutation of tumor suppressor genes and overexpression of anti-apoptotic genes permitting cell survival. Thus, inducing the apoptotic process in various ways can be applied to cancer management. Besides, angiogenesis is a crucial process for tumor growth and metastasis. New strategies targeting fundamental play-markers of the angiogenic process are currently under investigation.


5. DOCID:23917 SCORE: 0.00225374623685073
DOCNO: 9155138
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: M Kamiyoshihara M
AUTHOR: T Hirai T
AUTHOR: O Kawashima O
AUTHOR: Y Morishita Y
AFFILIATION: Department of Surgery, National Sanatorium Nishigunma Hospital, Gunma, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: [Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai.
COUNTRY: JAPAN
TITLE: [Video-assisted thoracoscopic surgery for a 89-year-old patient with primary lung cancer--report of a case]
PUBDATE: 19970401
A 89-year-old woman was referred to our hospital because of a relatively defined shadow of the right peripheral lung in chest roentgenograms. Although this case couldn't be diagnosed with transbronchial lung biopsy, adenocarcinoma of the lung (c-T1N0M0) was suspected because of radiological findings. We planned video-assisted pulmonary partial resection of the S6 in consideration of age and general status. Her postoperative courses was uneventful with no complications. Video-assisted thoracoscopic surgery is one of the treatments for elderly patients with peripheral early stage lung cancer.


6. DOCID:23980 SCORE: 0.00225372643738775
DOCNO: 9257067
AUTHOR: J E Herndon JE
AUTHOR: S Fleishman S
AUTHOR: M P Kosty MP
AUTHOR: M R Green MR
AFFILIATION: CALGB Statistical Center, Duke University Medical Center, Durham, North Carolina 27705, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Controlled clinical trials.
COUNTRY: UNITED STATES
TITLE: A longitudinal study of quality of life in advanced non-small cell lung cancer: Cancer and Leukemia Group B (CALGB) 8931.
PUBDATE: 19970801
A quality of life (QOL) endpoint supplemented standard clinical endpoints of survival, tumor response, and toxicity in a double-blind study conducted by the Cancer and Leukemia Group B (CALGB) where 291 patients with advanced non-small cell lung cancer (NSCLC) were randomly assigned to receive cisplatin/vinblastine with either hydrazine sulfate (HS) or placebo. The difficulties associated with the analysis of the longitudinal QOL data, and the contributions that the QOL endpoint made to the understanding of treatment differences, will be the focus of this paper.


7. DOCID:31385 SCORE: 0.00218704953771545
DOCNO: 15712516
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
QUALIFIER: therapy
AUTHOR: Cristina Opasich C
AUTHOR: Giuseppina Majani G
AFFILIATION: Divisione di Cardiologia, Istituto Scientifico, Fondazione S. Maugeri, Clinica del Lavoro e della Riabilitazione, IRCCS Pavia. copasich@fsm.it
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Italian heart journal : official journal of the Italian Federation of Cardiology.
COUNTRY: Italy
TITLE: [End-of-life care in elderly heart failure patients]
PUBDATE: 20041201
Even if improved, the prognosis of chronic heart failure is still malignant, survival rate being similar to that of cancer. Due to the relevant epidemiology of the disease in the elderly, the terminal care of heart failure has a significant impact. Improving end-of-life care (by improving quality of life, quality of cure and care at the end of life and quality of dying and death) is a major challenge for health providers involved in heart failure care.


8. DOCID:26302 SCORE: 0.00218271244943124
DOCNO: 11114421
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: prevention & control
QUALIFIER: prevention & control
QUALIFIER: immunology
AUTHOR: C Hatzifoti C
AUTHOR: B W Wren BW
AUTHOR: W J Morrow WJ
AFFILIATION: Dept of Immunology, St Bartholomew's and the Royal London School of Medicine and Dentistry, 38 Little Britain, EC1A 7BE, London, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Immunology today.
COUNTRY: ENGLAND
TITLE: Helicobacter pylori vaccine strategies--triggering a gut reaction.
PUBDATE: 20001201
Helicobacter pylori causes peptic ulcer disease and some forms of gastric cancer; it is one of the most common chronic bacterial infections of humans. Although several prototype protein-based vaccines have shown promising results, they have not cleared infection and/or prevented reinfection. Nucleic acid vaccination offers a useful alternative to protein immunization, especially now that two complete H. pylori genome sequences are available, and facilitates the selection of antigenic targets.


9. DOCID:27358 SCORE: 0.00213795409848736
DOCNO: 10996485
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: toxicity
QUALIFIER: physiology
AUTHOR: L Brunetti L
AUTHOR: G Orlando G
AUTHOR: B Michelotto B
AUTHOR: L Recinella L
AUTHOR: E Ragazzoni E
AUTHOR: M Vacca M
AFFILIATION: Department of Drug Sciences, G. D'Annunzio University, via dei Vestini, 66013, Chieti, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Toxicology letters.
COUNTRY: NETHERLANDS
TITLE: A possible prolactin-related adverse effect of certain antineoplastic anthracyclines.
PUBDATE: 20000801
Nonhormonal antineoplastic therapy can affect the endocrine system with consequent effects on the growth of hormone-sensitive tumors. Amongst anthracycline antibiotics, we have found daunorubicin and epirubicin able to acutely stimulate prolactin (PRL) secretion both in vivo, in the rat, and in vitro, from rat anterior pituitary cell cultures. Despite a similar structure, doxorubicin showed no such activity. Considering the possible role of PRL in breast cancer cell proliferation, the effects of certain anthracyclines might be viewed as an adverse drug reaction involving the anterior pituitary gland.


10. DOCID:27410 SCORE: 0.00213792431527057
DOCNO: 9560532
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: M Kanazawa M
AUTHOR: T Maruyama T
AUTHOR: T Suzuki T
AUTHOR: K Soejima K
AUTHOR: M Hayashi M
AUTHOR: K Yamazaki K
AFFILIATION: Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.
PUBTYPE: Case Reports
PUBTYPE: Clinical Conference
PUBTYPE: Journal Article
JOURNALTITLE: The Keio journal of medicine.
COUNTRY: JAPAN
TITLE: A case of rapidly progressing small cell lung cancer incidentally found during the course of renal failure.
PUBDATE: 19980301
A 65-year-old man with rapidly progressing small cell lung cancer found in the course of renal failure is reported. The patient had a medical history of hypertension, diabetes mellitus, and cardiovascular disease. Hemodialysis was introduced following renal failure, but pneumonia resulted in a transient exacerbation and his complaint of general fatigue did not improve. Examination for the fatigue revealed no apparent abnormalities. Three months later, he died of small cell lung cancer.


11. DOCID:27414 SCORE: 0.00213792207585347
DOCNO: 11754419
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: A Raj A
AUTHOR: R Bendon R
AUTHOR: T Moriarty T
AUTHOR: C Suarez C
AUTHOR: S Bertolone S
AFFILIATION: Department of Pediatric Hematology/Oncology, University of Louisville, Louisville, Kentucky 40202, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of hematology.
COUNTRY: United States
TITLE: Langerhans cell histiocytosis following childhood acute lymphoblastic leukemia.
PUBDATE: 20011201
Langerhans cell histiocytosis (LCH) is a clonal proliferation of Langerhans cells of unknown etiology that results in a range of clinical manifestations. LCH has been known to be associated with a variety of malignant diseases. A 7-year-old boy was treated for standard-risk acute lymphoblastic leukemia (ALL) at age 2 years, on a Children's Cancer Group chemotherapy protocol for 3 years and developed LCH 2 years after completion of chemotherapy. The case and a review of literature on the association of LCH and ALL are presented.


12. DOCID:22799 SCORE: 0.00212433795295185
DOCNO: 8896111
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ultrasonography, Mammary
AUTHOR: V P Jackson VP
AUTHOR: H E Reynolds HE
AUTHOR: D R Hawes DR
AFFILIATION: Department of Radiology, Indiana University School of Medicine, Indianapolis 46202, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in ultrasound, CT, and MR.
COUNTRY: UNITED STATES
TITLE: Sonography of the breast.
PUBDATE: 19961001
Quality mammography remains the primary modality used to image the breast. Sonography currently is the most useful adjunctive technique to mammography, having roles in differentiating cystic from solid masses and in guiding interventional procedures. This article reviews these and other indications for breast ultrasound studies, including evaluation of palpable masses not visible in radiographically dense breasts, masses not completely evaluable with mammography, young patients especially susceptible to radiation damage, and abscesses. Ultrasound interpretation of cysts and solid masses are discussed, as are the relative disadvantages of ultrasound as a breast cancer screening tool.


13. DOCID:27921 SCORE: 0.00212305304093666
DOCNO: 10859696
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: pharmacology
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: B R Lackey BR
AUTHOR: S L Gray SL
AUTHOR: D M Henricks DM
AFFILIATION: Endocrine Physiology Laboratory, Department of Animal and Veterinary Science, Clemson University, South Carolina, USA. blackey@clemson.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Medical hypotheses.
COUNTRY: SCOTLAND
TITLE: Synergistic approach to cancer therapy: exploiting interactions between anti-estrogens, retinoids, monoterpenes and tyrosine kinase inhibitors.
PUBDATE: 20000501
Non-responsiveness and toxicity are large problems encountered during cancer treatment. Utilization of compounds that synergize should increase treatment efficacy while avoiding problems of toxicity. This review explores interactions between classes of compounds, including anti-estrogens, retinoids, monoterpenes and tyrosine kinase inhibitors, that are effective independent, and how their synergistic interaction could be exploited in cancer treatment. The effects of these compounds on insulin-like growth factors (IGF) and transforming-growth factor-beta (TGF-beta) will also be examined.


14. DOCID:18863 SCORE: 0.0020582987329705
DOCNO: 1509462
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: adverse effects
AUTHOR: F Samdal F
AUTHOR: P F Amland PF
AUTHOR: K C Skolleborg KC
AUTHOR: F Abyholm F
AFFILIATION: Plastisk kirurgisk avdeling, Rikshospitalet, Oslo.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Tidsskrift for den Norske laegeforening.
COUNTRY: NORWAY
TITLE: [Are silicone breast prostheses dangerous?]
PUBDATE: 19920601
Since 1964 silicone breast prostheses have been implanted in 5 million women for breast reconstruction after cancer operations, to correct congenital deformities and for cosmetic reasons. There is no evidence in the literature of a correlation between silicone implants and breast cancer. Some authors claim that silicone implants reduce the reliability of mammography. Autoimmune diseases in patients with silicone mammary implants are reported in less than 40 cases. Most of these are localized or systemic scleroderma. An association with silicone implants has been suggested, but this suggestion has not been confirmed by scientific data.