0. DOCID:3734 SCORE: 0.00279695560822604
DOCNO: 1176552
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: surgery
QUALIFIER: complications
AUTHOR: M Guivarc'h M
AUTHOR: J Marquand J
AUTHOR: B Chiche B
AUTHOR: A Mouchet A
PUBTYPE: Journal Article
JOURNALTITLE: Journal de chirurgie.
COUNTRY: FRANCE
TITLE: [Surgical methods in non-traumatic perforations of the colon into the free peritoneum (36 cases)]
PUBDATE: 19750301
When operating as an emergency for a perforation of the colon should one carry out a by-pass operation, colostomy or restore intestinal continuity? 36 colonic perforations are reported here, as a complication of cancer in 50 p. 100 of cases, or sigmoiditis in 38 p. 100 of cases. The perforation was situated on the sigmoid in 77 p. 100 of cases. 13 by-pass operations were carried out with a 23 p. 100 mortality, 12 colectomies without anastomosis with a 50 p. 100 mortality, and 2 colectomies with restoration of continuity, 9 p. 100 mortality. The overall mortality was 27.7 p. 100 much less than reported by other authors but, nevertheless partly due to the severity of peritonitis due to the presence of feces and, partly due to the operation adopted. The present attitude of the authors depends on the merits of each case. A large incision is made and the peritoneum thoroughly cleaned. If the surgeon is experienced, colonic resection is advisable for perforated cnacer and certain cases of sigmoiditis. Restoration of continuity depends, above all, on the anatomical condition of the colon above the lesion. Hartmann's resections or by-pass operations thus still have indications.


1. DOCID:23267 SCORE: 0.00256685937500105
DOCNO: 7658533
AUTHOR: K J Ho KJ
AFFILIATION: Department of Laboratory Medicine, National Taiwan University, College of Medicine, Taipei.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy.
PUBDATE: 19951001
PURPOSE: The usefulness of urinary beta-glucuronidase in screening and followup of urinary tract malignancy was tested. MATERIALS AND METHODS: The activity and concentration of urinary beta-glucuronidase were determined in 80 healthy subjects, 113 urology patients with no cancer, and 60 with transitional cell and 23 with renal cell carcinoma. Patients with cancer were followed for 3 to 33 weeks. RESULTS: The enzyme activity and concentration were significantly greater in the cancer group, including residual tumor or recurrence after therapy, than in the controls with excellent discrimination. CONCLUSIONS: Urinary beta-glucuronidase was indeed useful in screening and followup of urinary tract malignancy.


2. DOCID:14674 SCORE: 0.00253279603876608
DOCNO: 3175558
AUTHOR: C E Minder CE
AUTHOR: J P Vader JP
AFFILIATION: Department of Social and Preventive Medicine, University of Berne, Switzerland.
PUBTYPE: Journal Article
JOURNALTITLE: Scandinavian journal of work, environment & health.
COUNTRY: FINLAND
TITLE: Malignant pleural mesothelioma among Swiss furniture workers. A new high-risk group.
PUBDATE: 19880801
Within the framework of a research project concerning occupational mortality, attention was drawn to a highly significant standardized mortality ratio for mesothelioma among furniture workers. From information drawn from the mortality records for the years 1979-1985 and from the 1980 national census, the number of pleural mesotheliomas among this occupational group was examined. The expected number of deaths from pleural mesothelioma among Swiss furniture workers for this period was 4.4; the observed number was 12. This finding indicates a 2.7-fold relative risk (P = 0.004) for death due to these cancers among Swiss furniture workers.


3. DOCID:3418 SCORE: 0.00242029040338402
DOCNO: 3117
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: M A Batata MA
AUTHOR: W F Whitmore WF
AUTHOR: B S Hilaris BS
AUTHOR: N Tokita N
AUTHOR: H Grabstald H
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: UNITED STATES
TITLE: Cancer of the undescended or maldescended testis.
PUBDATE: 19760201
An analysis of 45 cryptorchids (by history or examination) with a testicular cancer treated at Memorial Hospital, between 1934 and 1973, is presented. Twenty-five patients had the cryptorchid state repaired at ages four to 27 years, either spontaneously or by orchiopexy or hormonal therapy. Ipsilateral (24) or contralateral (one) intrascrotal testis tumors developed four to 47 years later. Twenty cryptorchid patients presented with ipsilateral inguinal (eleven), abdominal (seven), or contralateral intrascrotal (two) tumors. There were 18 pure seminomas, 17 embryonal carcinomas, nine teratocarcinomas, and one reticulum cell sarcoma. Five year survival rates as estimated by the product-limit method were 60% for the unrepaired cases and 41% for the repaired cases. The survival seems to follow histologic type and anatomical stage, whether the testis is within the scrotum or not. Five year survival similarly estimated was 78% in the seminomas and 29% in the other tumors. Twelve of thirteen survivors (including nine with seminoma) received postoperative irradiation to the regional lymphatics and eleven were without recurrent tumor for periods ranging from six to 28 years.


4. DOCID:11968 SCORE: 0.00240928374794398
DOCNO: 6702939
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ascitic Fluid
QUALIFIER: diagnosis
AUTHOR: S Yoshimura S
AUTHOR: R E Scully RE
AUTHOR: D A Bell DA
AUTHOR: P D Taft PD
PUBTYPE: Journal Article
JOURNALTITLE: American journal of obstetrics and gynecology.
COUNTRY: UNITED STATES
TITLE: Correlation of ascitic fluid cytology with histologic findings before and after treatment of ovarian cancer.
PUBDATE: 19840301
One hundred thirteen specimens of ascitic fluid from 97 patients with primary, persistent, or recurrent ovarian cancer were examined cytologically. Advanced stage of disease, involvement of the ovarian surface, a moderate or large volume of fluid, and nonbloody serous ascites were factors that correlated with a high rate of positive findings in ascites in these patients. Other factors influencing the positive rate appeared to be the invasive as opposed to borderline malignant histology of the tumor. Involved external surface and volume of ascites were influencing factors only in advanced cases. Therefore, the most important factor influencing the positive rate of ascites cytology was the proportion of cases in advanced stages to total cases.


5. DOCID:17324 SCORE: 0.00235588092909713
DOCNO: 8390708
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: M D Isla Casado MD
AUTHOR: R Escó Barón R
AUTHOR: A Castillo Ramírez A
AFFILIATION: Servicio de Oncología Radioterápica, Hospital Clínico Universitario de Zaragoza.
PUBTYPE: Journal Article
JOURNALTITLE: Revista clínica española.
COUNTRY: SPAIN
TITLE: [Survival analysis in lung cancer treated with radiotherapy]
PUBDATE: 19930501
From June-78 to December-89, 300 patients with histologic diagnosis of non-small cell lung cancer were treated with radiotherapy by different indications: radical intention, post-chemotherapy, palliative intention, symptomatic and postsurgery. It was employed an electrons lineal accelerator principally, and for symptomatic radiotherapy treatment was used telegammatherapy by cobalt-60. It was treated an retrospective non comparative study which it has analyzed the survival of the different radiotherapy indications.


6. DOCID:30502 SCORE: 0.00234839009628168
DOCNO: 15678907
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: etiology
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: Hirokazu Taniguchi H
AUTHOR: Minehiko Inomata M
AUTHOR: Hitoshi Abo H
AUTHOR: Hideki Miyazawa H
AUTHOR: Hirofumi Noto H
AUTHOR: Saburo Izumi S
AFFILIATION: Department of Internal Medicine, Toyama Central Prefectural Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society.
COUNTRY: Japan
TITLE: [Central diabetes insipidus caused by pituitary metastasis of lung cancer]
PUBDATE: 20041201
A 53-year-old man admitted for thirst, polyposia, and polyuria. Large cell lung cancer T3N2M1 (Stage IV), and central diabetes insipidus caused by pituitary metastasis of lung cancer, were diagnosed. We gave him desmopressin acetate, and chemotherapy with paclitaxel and carboplatin. But pituitary metastasis increased and invaded the hypothalamus. After irradiation of the pituitary and hypothalamus, metastatic focus diminished and desmopressin acetate was tapered.


7. DOCID:30153 SCORE: 0.00234588102541428
DOCNO: 15830146
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: secondary
QUALIFIER: drug therapy
QUALIFIER: pathology
QUALIFIER: therapeutic use
AUTHOR: Mark Clemons M
AUTHOR: Sunil Verma S
AFFILIATION: Division of Medical Oncology, Toronto-Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. mark.clemons@sw.ca
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Breast cancer research and treatment.
COUNTRY: Netherlands
TITLE: Should oral bisphosphonates be standard of care in women with early breast cancer?
PUBDATE: 20050401
There is increasing evidence that oral clodronate has important clinical benefits in early breast cancer. Longer-term follow-up data from two out of three randomized studies have shown that adjuvant clodronate improves survival. This article outlines the results of these studies and discusses the potential role for other bisphosphonates, such as ibandronate and zoledronic acid, in the adjuvant treatment of breast cancer.


8. DOCID:30214 SCORE: 0.00234587826450638
DOCNO: 15906369
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Apoptosis
DESCRIPTOR: Neovascularization, Pathologic
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: Jannis Kountouras J
AUTHOR: Christos Zavos C
AUTHOR: Dimitrios Chatzopoulos D
AFFILIATION: Department of Medicine, Second Medical Clinic, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece. jannis@med.auth.gr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: United States
TITLE: Apoptotic and anti-angiogenic strategies in liver and gastrointestinal malignancies.
PUBDATE: 20050601
Inappropriate suppression of apoptosis is strongly implicated in tumorigenesis. Tumor development is heralded by the mutation of tumor suppressor genes and overexpression of anti-apoptotic genes permitting cell survival. Thus, inducing the apoptotic process in various ways can be applied to cancer management. Besides, angiogenesis is a crucial process for tumor growth and metastasis. New strategies targeting fundamental play-markers of the angiogenic process are currently under investigation.


9. DOCID:3837 SCORE: 0.00233030131418485
DOCNO: 856959
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: G J Draper GJ
AUTHOR: M M Heaf MM
AUTHOR: L M Kinnier Wilson LM
PUBTYPE: Journal Article
JOURNALTITLE: Journal of medical genetics.
COUNTRY: UNITED STATES
TITLE: Occurrence of childhood cancers among sibs and estimation of familial risks.
PUBDATE: 19770401
An analysis which includes the majority of the cases of childhood cancer occurring in Britain over a period of about 20 years suggests that there is a small familial element in the aetiology of these diseases; aggregations within sibships were observed more frequently than would be expected by chance. Possible explanations of these findings are considered. Some, perhaps many, of the cases within such sibships may be due to associations between malignant disease and various genetically determined conditions at a suclinical level or in the heterozygous state. Alternatively, the observed familial aggregations may be attributable to the fact that sibs share a common environment. Childhood cancer in twins is discussed and findings compared with those from the United States. Attention is drawn to a number of interesting combinations of tumours in sibs, particularly brain tumours and bone cancers. The implications of the findings for genetic counselling are discussed; it is emphasized that, though there appears to be an increased risk that sibs of children with malignant disease will also be affected by such diseases, this amounts overall only to a doubling of the general population risk. Whether or not the explanation is a genetic one, the actual magnitude of the risk for such sibs is only about 1 in 300.


10. DOCID:3283 SCORE: 0.00232524980339228
DOCNO: 195975
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Complement Fixation Tests
DESCRIPTOR: Cytotoxicity Tests, Immunologic
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: T Subramanian T
AUTHOR: W E Rawls WE
PUBTYPE: Journal Article
JOURNALTITLE: Journal of clinical microbiology.
COUNTRY: UNITED STATES
TITLE: Comparison of antibody-dependent cellular cytotoxicity and complement-dependent antibody lysis of herpes simplex virus-infected cells as methods of detecting antiviral antibodies in human sera.
PUBDATE: 19770601
An antibody-dependent cellular cytotoxicity (ADCC) assay was used to detect antibodies to the herpes simplex viruses in humans sera. The assay utilized the release of 51Cr from BHK-21 cells infected with the viruses, hamster peritoneal exudate cells as effector cells, and antiviral antibodies in human sera. The technique was found to be far more sensitive than complement-dependent antibody lysis of infected cells and virus neutralization. The ADCC assay was useful in detecting antibodies in sera that had low titers or no antibodies detectable by other methods. In a sample of 100 sera from university students, 40 were positive by complement-dependent lysis whereas 73 were positive by ADCC. Of 400 sera from women with cervical cancer, 17 did not have detectable antibodies by microneutralization or complement-dependent lysis; however, all sera were positive by ADCC, suggesting that all of the women had been infected in the past with one or both types of herpes simplex virus.


11. DOCID:3449 SCORE: 0.00230746522269689
DOCNO: 1160463
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Glottis
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: E Bocca E
PUBTYPE: Journal Article
JOURNALTITLE: The Laryngoscope.
COUNTRY: UNITED STATES
TITLE: Supraglottic cancer.
PUBDATE: 19750801
Supraglottic cancer, because of the embryological development of the larynx, and of the arrangement of its lymphatic network, tends to remain limited within the vestibule of the larynx and the pre-epiglottic space also in its advanced stages of evolution. The cancer spread may superiorly involve the epilarynx, the vallecula, the base of the tongue, and the pyriform fossa; however, inferiorly, the invasion of the glottis is quite exceptional (1 percent of cases); therefore, supraglottic laryngectomy is the operation of choice. The lower the location of cancer in the vestibule, the safer the indication. The higher location generally requires an extension of surgical excision toward the tongue, arytenoids and hypopharnx. In view of the high percentage of lymph node metastases, supraglottic laryngectomy should be associated with neck dissection, mainly bilateral, also in cases with no evidence of enlarged lymph nodes. Supraglottic laryngectomy has been performed in 240 cases in the course of the last 14 years and the five-year cure rate has been 79 percent. Five postoperative deaths have been recorded. Rehabilitation time for the breathing and swallowing function has been three weeks as an average. Complications, such as fistula or infection have been exceedingly rare: uneventful recovery followed in all cases.


12. DOCID:11800 SCORE: 0.00229334473748117
DOCNO: 6181700
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: M B Spaulding MB
AUTHOR: A Kahn A
AUTHOR: R De Los Santos R
AUTHOR: D Klotch D
AUTHOR: J M Loré JM
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Adjuvant chemotherapy in advanced head and neck cancer. An update.
PUBDATE: 19821001
Two courses of triple-agent chemotherapy were given to 47 patients with advanced head and neck cancer. All but one patient with a nasopharyngeal carcinoma had resectable stage III and IV squamous cell carcinoma. Eighty-eight percent of the patients responded to the chemotherapy with a 50 percent or greater decrease in tumor size. Forty-three patients underwent surgical resection and 19 were histologically upgraded to stage II or better (T less than 2 cm, N0). None of these 19 patients have relapsed, with follow-up ranging from 12 to 42 months. In 12 of the 47 patients, recurrent tumor developed within the first 18 months of follow-up.


13. DOCID:23917 SCORE: 0.00225374623685073
DOCNO: 9155138
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: M Kamiyoshihara M
AUTHOR: T Hirai T
AUTHOR: O Kawashima O
AUTHOR: Y Morishita Y
AFFILIATION: Department of Surgery, National Sanatorium Nishigunma Hospital, Gunma, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: [Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai.
COUNTRY: JAPAN
TITLE: [Video-assisted thoracoscopic surgery for a 89-year-old patient with primary lung cancer--report of a case]
PUBDATE: 19970401
A 89-year-old woman was referred to our hospital because of a relatively defined shadow of the right peripheral lung in chest roentgenograms. Although this case couldn't be diagnosed with transbronchial lung biopsy, adenocarcinoma of the lung (c-T1N0M0) was suspected because of radiological findings. We planned video-assisted pulmonary partial resection of the S6 in consideration of age and general status. Her postoperative courses was uneventful with no complications. Video-assisted thoracoscopic surgery is one of the treatments for elderly patients with peripheral early stage lung cancer.


14. DOCID:23980 SCORE: 0.00225372643738775
DOCNO: 9257067
AUTHOR: J E Herndon JE
AUTHOR: S Fleishman S
AUTHOR: M P Kosty MP
AUTHOR: M R Green MR
AFFILIATION: CALGB Statistical Center, Duke University Medical Center, Durham, North Carolina 27705, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Controlled clinical trials.
COUNTRY: UNITED STATES
TITLE: A longitudinal study of quality of life in advanced non-small cell lung cancer: Cancer and Leukemia Group B (CALGB) 8931.
PUBDATE: 19970801
A quality of life (QOL) endpoint supplemented standard clinical endpoints of survival, tumor response, and toxicity in a double-blind study conducted by the Cancer and Leukemia Group B (CALGB) where 291 patients with advanced non-small cell lung cancer (NSCLC) were randomly assigned to receive cisplatin/vinblastine with either hydrazine sulfate (HS) or placebo. The difficulties associated with the analysis of the longitudinal QOL data, and the contributions that the QOL endpoint made to the understanding of treatment differences, will be the focus of this paper.