0. DOCID:26927 SCORE: 0.00336956141981329
DOCNO: 11140227
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: adverse effects
QUALIFIER: administration & dosage
QUALIFIER: adverse effects
QUALIFIER: drug therapy
AUTHOR: J A Low JA
AUTHOR: R Chye R
AFFILIATION: Department of Palliative Care, Prince of Wales Hospital, New South Wales. jamesalvinlow@hotmail.com
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Australian family physician.
COUNTRY: Australia
TITLE: A pitfall to avoid when starting a patient on transdermal fentanyl.
PUBDATE: 20001201
BACKGROUND: A woman with advanced carcinoma of the ovary developed fentanyl toxicity while being changed from oral morphine to transdermal fentanyl. OBJECTIVE: To explain the reason for the toxicity and ways to avoid it. DISCUSSION: The transdermal fentanyl patch is proving to be a safe, well tolerated and effective treatment modality in the control of cancer pain, but care has to be exercised when using this drug, especially at the time of initiation, as the consequences may be disastrous for the patient.


1. DOCID:23961 SCORE: 0.00312046074347326
DOCNO: 7796196
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Women, Working
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: G Wingren G
AUTHOR: A Hallquist A
AUTHOR: A Degerman A
AUTHOR: L Hardell L
AFFILIATION: Department of Occupational Medicine, University Hospital, Linköping, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine.
COUNTRY: UNITED STATES
TITLE: Occupation and female papillary cancer of the thyroid.
PUBDATE: 19950301
This article presents the joint results of two Swedish case-control studies regarding occupational exposure and female papillary thyroid cancer. Questionnaires inquiring about lifetime occupations and specific occupational exposures were mailed to cases and controls, aged 20 to 70 years. Some 185 female papillary or mixed cancer cases and 426 female controls were included in the analysis. Increased risks were seen for women who had worked as a dentist/dental assistant, teacher, shoemaker, or warehouse worker. In addition, occupational contacts with undefined chemicals, x-rays, or video display terminals were indicated as risk factors.


2. DOCID:19924 SCORE: 0.00287605695582356
DOCNO: 2161782
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Adenocarcinoma
DESCRIPTOR: Breast Neoplasms
DESCRIPTOR: Carcinoma, Intraductal, Noninfiltrating
DESCRIPTOR: Neoplasms, Multiple Primary
DESCRIPTOR: Uterine Neoplasms
AUTHOR: G Atlante G
AUTHOR: M Pozzi M
AUTHOR: C Vincenzoni C
AUTHOR: G Vocaturo G
AFFILIATION: Department of Gynecological Oncology, Regina Elena National Cancer Institute, Rome, Italy.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Four case reports presenting new acquisitions on the association between breast and endometrial carcinoma.
PUBDATE: 19900601
In recent years, the association between breast and endometrial cancer has been the subject of many studies. The present report describes four cases of this association in which tamoxifen had been administered to all of the patients. Data have been published regarding the possibility that tamoxifen may be responsible for the subsequent development of carcinoma of the corpus uteri in these patients. The authors intend to carry out a case-control study on patients treated with tamoxifen for breast carcinoma to reveal the possible presence of endometrial carcinoma.


3. DOCID:26990 SCORE: 0.00285209022784133
DOCNO: 9666047
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: L D Tomei LD
AUTHOR: S R Umansky SR
AFFILIATION: LXR Biotechnology Incorporated, Richmond, California 94804, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Neurologic clinics.
COUNTRY: UNITED STATES
TITLE: Aging and apoptosis control.
PUBDATE: 19980801
The phenomenon of aging is distinct from processes associated with advanced age known to increase risk of diseases, such as cancer. Furthermore, the process of aging is not necessarily related to phenomena such as in vitro replicative senescence; however, any unifying hypothesis of aging must account for all age-dependent phenomena, including senescence. It is proposed that apoptosis forms the ultimate protective process for preservation of phenotypic fidelity in multicellular organisms since it is the process by which the organism detects damage and replaces the defective cell. Time-dependent degeneration of apoptosis control is the rate-limiting step in the process of aging.


4. DOCID:28642 SCORE: 0.00279742518057137
DOCNO: 15350945
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: pathology
QUALIFIER: therapy
AUTHOR: Henry Q Xiong HQ
AUTHOR: James L Abbruzzese JL
AFFILIATION: Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: United States
TITLE: Adjuvant therapy for pancreatic cancer: current status and future directions.
PUBDATE: 20041001
This article summarizes the important past and ongoing adjuvant therapy trials for pancreatic cancer. The recent developments in the fields of radiosensitization, chemotherapy, and molecular-targeted therapy are outlined. Finally, the future study strategies for adjuvant therapy trials are discussed.


5. DOCID:19970 SCORE: 0.00271480511787259
DOCNO: 1717224
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: drug therapy
QUALIFIER: complications
AUTHOR: P A Todd PA
AUTHOR: A Fitton A
AFFILIATION: Adis International Limited, Auckland, New Zealand.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Drugs.
COUNTRY: NEW ZEALAND
TITLE: Gallium nitrate. A review of its pharmacological properties and therapeutic potential in cancer related hypercalcaemia.
PUBDATE: 19910801
Gallium nitrate, a novel drug for the treatment of cancer-related hypercalcaemia, inhibits osteoclast activity but does not affect osteoclast morphology or viability. Limited clinical experience in patients with cancer-related hypercalcaemia indicates that gallium nitrate is effective in restoring normocalcaemia in 75 to 85% of patients and is well tolerated in those with preserved renal function, producing few clinically relevant adverse effects. In comparative clinical trials it proved a more effective antihypercalcaemic agent than calcitonin or etidronate and produced a longer lasting normocalcaemic response. Gallium nitrate would appear to be indicated in symptomatic patients with cancer-related hypercalcaemia who have failed to respond to adequate rehydration.


6. DOCID:23782 SCORE: 0.00270098085977145
DOCNO: 8085087
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J A Pérez JA
AUTHOR: R Silva R
AUTHOR: M del Pozo M
AUTHOR: E Henning E
AFFILIATION: Instituto de Cirugía, Facultad de Medicina, Universidad Austral de Chile, Valdivia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revista médica de Chile.
COUNTRY: CHILE
TITLE: [Diffuse hyperthyroid goiter associated with occult papillary carcinoma of the thyroid. Report of 2 cases]
PUBDATE: 19940201
The association of diffuse hyperthyroid goiter and thyroid cancer is rare and interesting, considering that both diseases affect the same organ but have different pathogenesis and prognosis. We report two patients that consulted for diffuse hyperthyroid goiter and were subjected to a subtotal bilateral thyroidectomy due to antithyroid drug failure. Pathological study revealed the coexistence of diffuse gland hyperplasia and a papillary thyroid carcinoma of less than 7 mm phi. In both cases, the thyroid remanent was ablated with radioactive iodine during the postoperative period and thyroid substitution was started.


7. DOCID:29582 SCORE: 0.00267545561060353
DOCNO: 12663955
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Reproductive Medicine
QUALIFIER: therapy
AUTHOR: Helena Davies H
AUTHOR: Diana Greenfield D
AUTHOR: William Ledger W
AFFILIATION: Academic Unit of Child Health, Sheffield University, Sheffield Children's Hospital, Western Bank, Sheffield S10 2TH, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Human fertility (Cambridge, England)
COUNTRY: England
TITLE: Reproductive medicine in a late effects of cancer clinic.
PUBDATE: 20030201
This review discusses the most commonly observed problems in young people who have survived childhood cancer, with particular emphasis on the issues of fertility. It also describes the role of the late effects clinic in transitional care and the multidisciplinarity of the clinicians required to meet the needs of these young people. There is a need for evidence-based guidelines for management of long-term survivors.


8. DOCID:21397 SCORE: 0.00267228308057991
DOCNO: 7734605
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
DESCRIPTOR: Patient Acceptance of Health Care
DESCRIPTOR: Vaginal Smears
QUALIFIER: statistics & numerical data
QUALIFIER: prevention & control
AUTHOR: A Ruge A
AUTHOR: C Lee C
AUTHOR: W J Brown WJ
AFFILIATION: Department of Psychology, University of Newcastle.
PUBTYPE: Journal Article
JOURNALTITLE: Australian journal of public health.
COUNTRY: AUSTRALIA
TITLE: Inpatient cervical screening: a survey of patient acceptability.
PUBDATE: 19950201
Offering Pap tests to hospital inpatients could increase cervical screening rates. A survey to examine the acceptability of this concept was conducted with female inpatients in a rural public hospital. A large majority reported that they would find hospital Pap tests acceptable. Acceptability was not related to Pap test status, attitudes, or knowledge of cervical cancer. This strategy may provide access to cervical screening for underscreened groups.


9. DOCID:26823 SCORE: 0.00266622761179925
DOCNO: 11424473
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Anesthesia, Epidural
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: complications
AUTHOR: T Hamada T
AUTHOR: K Katori K
AUTHOR: K Nitahara K
AUTHOR: T Shiratake T
AUTHOR: T Kaneko T
AUTHOR: K Higa K
AFFILIATION: Department of Anesthesiology, School of Medicine, Fukuoka University, Fukuoka 814-0180.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Masui. The Japanese journal of anesthesiology.
COUNTRY: Japan
TITLE: [Anesthetic management of a patient with tetanus using epidural anesthesia]
PUBDATE: 20010501
A 75-year-old woman with breast cancer complicated with tetanus was scheduled for mastectomy. Since severe bradycardia (17 beats.min-1) was detected by preoperative Holter monitoring, a temporary pacing catheter was inserted. She underwent mastectomy under general anesthesia using propofol combined with thoracic epidural anesthesia. She also received postoperative thoracic epidural block. Her perioperative heart rate was 80-105 beats.min-1 and the rhythm was sinus. There was no marked perioperative cardiovascular derangement.


10. DOCID:31107 SCORE: 0.00265512673401437
DOCNO: 15775352
OWNER: NLM
STATUS: PubMed-not-MEDLINE
AUTHOR: Toshio Okano T
AUTHOR: Kimie Nakagawa K
AFFILIATION: Kobe Pharmaceutical University, Department of Hygienic Science.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical calcium.
COUNTRY: Japan
TITLE: [Novel vitamin d analogues with selective biological activities]
PUBDATE: 20020501
1alpha,25-dihydroxyvitamin D(3) (1alpha,25 (OH)(2)D(3)) is a naturally occuring organic compound showing strong calcemic activity and anti-proliferative/differentiation-inducing activity. 1alpha,25 (OH)(2)D(3) is expected to be a therapeutic agent for metabolic bone diseases and cancer treatment. To enhance its selectivity, specificity, and safety as a therapeutic agent, it is required to separate its calcium-regulating activity from its non-calcium-regulating activity. For this reason, a variety of vitamin D analogues have been developed. The analogues with modification of A-ring are promising candidates for this purpose.


11. DOCID:22843 SCORE: 0.00265203225946249
DOCNO: 7979425
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusion Pumps, Implantable
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: Y Hata Y
AUTHOR: S Morita S
AUTHOR: N Hisa N
AUTHOR: Y Fujiwara Y
AUTHOR: T Higaki T
AUTHOR: O Kamiike O
AUTHOR: D Yoshida D
AUTHOR: S Yoshida S
AFFILIATION: Dept. of Radiology, Kochi Medical School.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Evaluation of arterial infusion chemotherapy for advanced gallbladder cancer using implantable port]
PUBDATE: 19941101
Seven patients with advanced gallbladder cancer were treated by arterial infusion chemotherapy. Five patients had unresectable tumor, and two had liver metastases after resection of primary tumor. The response rate was 42.9% (3 PR), and the 1-year survival rate was 35.7%. No severe side effect was found. We conclude that arterial infusion chemotherapy is effective for advanced gallbladder cancer, and that a more effective regimen and adjuvant therapy should be established.


12. DOCID:27186 SCORE: 0.00262587146839029
DOCNO: 10082411
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Colonoscopy
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: J H Bond JH
AFFILIATION: Gastroenterology Section, Minneapolis Veterans' Association Medical Center and University of Minnesota, 55417, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Endoscopy.
COUNTRY: GERMANY
TITLE: Colon polyps and cancer.
PUBDATE: 19990101
A number of recent publications dealing with colon polyps and cancer emphasize cost-effectiveness and the outcomes of screening and follow-up surveillance of high-risk groups. These groups include patients with either a past personal history or a family history of colorectal adenomas or cancer. Several papers address the effectiveness and compliance with different methods of screening of the asymptomatic, average-risk population for colorectal neoplasia. Other important publications deal with colorectal cancer prevention, the natural history of the adenoma-carcinoma sequence, diagnosis of polyps and cancer, colonoscopic polypectomy, management of the patient with a malignant polyp, and endoscopic treatment of obstructing cancer.


13. DOCID:26673 SCORE: 0.00262268948242086
DOCNO: 10748670
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Carcinogens
QUALIFIER: chemically induced
QUALIFIER: chemically induced
AUTHOR: A Bergeret A
AUTHOR: J C Normand JC
AFFILIATION: Service des maladies professionnelles et de médecine du travail, Centre hospitalier Lyon-Sud, Pierre-Bénite.
PUBTYPE: Journal Article
JOURNALTITLE: La Revue du praticien.
COUNTRY: FRANCE
TITLE: [Chemical-induced cancers]
PUBDATE: 20000201
Most chemical carcinogenic agents are industrial. About 4% of all cancers have an occupational origin, but the percentage is higher in exposed populations. Evidence of carcinogenicity is provided by epidemiological studies, animal experiments and other biological sources like experimental mutagenesis. The IARC (International Agency for Research on Cancer) classification and the European Union classification of carcinogenic agents for humans are useful for prevention and regulation. Some cancers are classified as occupational diseases but only a few persons receive compensation given the difficulties of aetiologic diagnosis and the frequent absence of declaration.


14. DOCID:26714 SCORE: 0.00262268770613575
DOCNO: 11503270
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: pharmacology
QUALIFIER: antagonists & inhibitors
AUTHOR: M Dzielska-Olczak M
AUTHOR: S Olczak S
AFFILIATION: Zakład Farmakologii Akademii Medycznej w łodzi.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.
COUNTRY: Poland
TITLE: [Clinical application of cyclooxygenase-2 inhibitors]
PUBDATE: 20010601
Nonsteroidal antiinflammatory drugs (NSAIDs) are a group of compounds with similar therapeutic and side effects. Their therapeutic effects depend on blockade of prostaglandin synthesis through enzyme cyclooxygenase (COX) inhibition. Two isoforms of the enzyme cyclooxygenase have been identified: COX-1 and COX-2. Selective COX-2 inhibitors i.e. meloxicam, nimesulid, etodolac or highly selective COX-2 inhibitors i.e. celecoxib, rofecoxib have antiinflammatory and analgesic properties with less or no gastrointestinal or other NSAIDs-typical adverse effects. Highly selective COX-2 inhibitors may also be active in colonic polyposis, colorectal cancer and Alzheimer's disease.