0. DOCID:31113 SCORE: 0.00180557556040005
DOCNO: 12413928
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genetic Predisposition to Disease
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: Paul D P Pharoah PD
AUTHOR: Bruce A J Ponder BA
AFFILIATION: Department of Oncology, University of Cambridge, Strangeways Research Laboratories, Worts Causeway, Cambridge, CB1 8RN, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Best practice & research. Clinical obstetrics & gynaecology.
COUNTRY: England
TITLE: The genetics of ovarian cancer.
PUBDATE: 20020801
A family history of ovarian cancer confers an increased risk of ovarian cancer. We review the literature quantifying the familial risks associated with ovarian cancer and assess the evidence that the familial clustering of ovarian cancer is genetically determined. We then describe the known high-penetrance genes, the ovarian cancer risks attached to them and their contribution to ovarian cancer in families and in the general population. The evidence for the existence of other ovarian cancer genes is then considered.


1. DOCID:30426 SCORE: 0.0017259269606288
DOCNO: 12625780
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Proteome
QUALIFIER: diagnosis
QUALIFIER: genetics
AUTHOR: Woonyoung Choi W
AUTHOR: Sonya W Song SW
AUTHOR: Wei Zhang W
AFFILIATION: Department of Pathology, The University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Technology in cancer research & treatment.
COUNTRY: United States
TITLE: Understanding cancer through proteomics.
PUBDATE: 20020801
Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies such as two-dimensional gel electrophoresis and mass spectrometry, complement genomic technologies, providing cancer researchers with powerful tools for cancer diagnosis and prognosis and for the identification of targets for therapy.


2. DOCID:30449 SCORE: 0.00172592537141712
DOCNO: 15055078
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymph Node Excision
QUALIFIER: surgery
AUTHOR: J Simsa J
AUTHOR: J Leffler J
AUTHOR: J Hoch J
AUTHOR: J Schwarz J
AUTHOR: P Bavor P
AFFILIATION: Chirurgická klinika 2. LF UK a FN Motol, Praha.
PUBTYPE: Journal Article
JOURNALTITLE: Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti.
COUNTRY: Czech Republic
TITLE: [Gastric carcinoma and D2 lymphadenectomy--technique and possible complications]
PUBDATE: 20040101
Lymphadenectomy in gastric cancer became vital and obligatory part of staging procedure. Therapeutic effect of lymphadenectomy with patient's prognosis improvement still remains uncertain. In subgroups, extensive lymphadenectomy enhance radicality of the procedure, enables to reach R0 resection in the area of tumour bed and hopefully improves survival. D2 lymphadenectomy is now becoming as a standard also in our country. Technique and possible complications of D2 lymphadenectomy are the matter of this article.


3. DOCID:29721 SCORE: 0.00160435246322322
DOCNO: 15045189
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
AUTHOR: V Köllner V
AUTHOR: K A Lautenschläger KA
AUTHOR: F-G Pajonk FG
AFFILIATION: Klinik für Psychotherapie und Psychosomatik, Universitätsklinikum Carl Gustav Carus, TU Dresden. koellner@psychosoma.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Der Urologe. Ausg. A.
COUNTRY: Germany
TITLE: [Psychooncology. New aspects for urology]
PUBDATE: 20040301
Cancer and psychiatric symptoms commonly co-occur. The frequency is about 50%, and those most important for urology are depression, anxiety, and probably post-traumatic stress disorder. There is a strong relationship between psychological distress and cancer pain. This review provides information on diagnostic and therapeutic strategies for psychiatric diseases, which are important for oncology patients in urology. Special advice is given for the doctor-patient relationship and communication.


4. DOCID:31520 SCORE: 0.00156368094624271
DOCNO: 15373081
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: secondary
AUTHOR: E Hartwig E
AUTHOR: L Kinzl L
AUTHOR: M Schultheiss M
AUTHOR: M Sarkar M
AFFILIATION: Klinik für Unfall-, Hand- und Wiederherstellungschirurgie Universität Ulm. erich.hartwig@medizin.uni-ulm.de
PUBTYPE: Journal Article
JOURNALTITLE: MMW Fortschritte der Medizin.
COUNTRY: Germany
TITLE: [Complications of malignant tumors--pathological fractures]
PUBDATE: 20040501
Advances in the treatment of tumors have improved the life expectancy of cancer patients appreciably. As a consequence the incidence of bone metastases has also increased. Surgical interventions must achieve a maximal palliative effect with minimal morbidity and mortality. Major objectives are reduction of pain while preserving stability and function. Surgical treatment of primary and secondary bone tumors is complicated and thus also burdened with complications. However, interdisciplinary therapy comprising surgical resection and stabilization, radiotherapy and/or chemotherapy improves life expectancy and the quality of life of the cancer patient.


5. DOCID:31176 SCORE: 0.00152451204725974
DOCNO: 15739767
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lipid Peroxidation
DESCRIPTOR: Tumor Burden
QUALIFIER: blood
QUALIFIER: blood
AUTHOR: G V Kireev GV
AUTHOR: O Iu Balenkov OIu
AUTHOR: F K Sharipov FK
AUTHOR: M D Dzhuraev MD
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia laboratornaia diagnostika.
COUNTRY: Russia
TITLE: [Lipid peroxidation and tumor dimensions in stomach cancer]
PUBDATE: 20041201
The parameters of lipid peroxidation were examined in blood serum of 40 patients with stomach cancer by induced chemiluminescence (CL)--Republican Research Center of Oncology, Healthcare Ministry of Uzbekistan. The CL parameters were demonstrated to increase alongside with the growing tumor mass. The induced CL of blood serum characterizes the status of lipid peroxidation and is a direct reflection of the body's reaction to tumor growth. The method of induced CL can be used on in clinical practice as an additional diagnostic test describing the tumor growth course in stomach cancer.


6. DOCID:30714 SCORE: 0.00148447246442985
DOCNO: 15714966
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Practice Guidelines
QUALIFIER: diagnosis
AUTHOR: Osamu Maeda O
AUTHOR: Michiyuki Usami M
AFFILIATION: Osaka Medical Center for Cancer and Cardiovascular Diseases.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: Japan
TITLE: [Summary of 'General Rule for Clinical and Pathological Studies on Prostate Cancer (the 3rd Edition)']
PUBDATE: 20050201
'General Rule for Clinical and Pathological Studies on Prostate Cancer(The 1st edition)' was published at 1985 by Japanese Urological Association and The Japanese Society of Pathology. It was revised in 1992 and the 2nd edition was published. Current diagnostic tests including prostate specific antigen (PSA) and biopsy technique have changed diagnosis and treatment of prostate cancer greatly. The 3rd edition was published in 2001 based on these changes. Here, the feature of the 3rd edition is outlined.


7. DOCID:30987 SCORE: 0.00148070508680616
DOCNO: 12580372
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: diagnosis
QUALIFIER: genetics
AUTHOR: Jon M Rowland JM
AFFILIATION: Department of Pathology, Children's Hospital and Research Center at Oakland, 747 52nd Street, Oakland, CA 94609, USA. jrowland@mail.cho.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Pediatric clinics of North America.
COUNTRY: United States
TITLE: Molecular genetic diagnosis of pediatric cancer: current and emerging methods.
PUBDATE: 20021201
A wide array of diagnostic tests are available to evaluate molecular abnormalities in pediatric cancer. Classic cytogenetics, FISH, flow cytometry, PCR, and Southern blot analysis are in widespread use throughout pediatric hospitals. Examples of the application of these methods in pediatric cancer diagnosis are reviewed. Newer methods such as CGH, SKY, gene expression microarrays and proteomic methods are under active investigation andwill almost certainly lead to significant advances in our ability to diagnose and treat pediatric cancer.


8. DOCID:31791 SCORE: 0.0014743404017861
DOCNO: 14978853
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: I Uhoda I
AUTHOR: C Piérard-Franchimont C
AUTHOR: J E Arrese JE
AUTHOR: P Quatresooz P
AUTHOR: F Cornil F
AUTHOR: F Deleixhe-Mauhin F
AUTHOR: G E Piérard GE
AFFILIATION: CHU du Sart Timan, Service de Dermatopathologie.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale de Liège.
COUNTRY: Belgium
TITLE: [How to investigate....A darkened skin lesion during pregnancy. A difficult task for the clinician]
PUBDATE: 20031201
Cancers rarely coexist with pregnancy. Cutaneous melanoma, however, is one of the most frequently encountered neoplasms during pregnancy. Gestation may also be a period during which the aspect of some melanocytic naevi can change eventhough the tumor remains benign. Distinction between a benign and a malignant lesion may then be a dilemma. Clinical morphometry, dermoscopy, skin surface biopsy, conventional histology and immunohistochemistry are valuable means that can be used to secure maximum diagnostic confidence.


9. DOCID:30845 SCORE: 0.00147061438631753
DOCNO: 14569384
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: surgery
AUTHOR: H Sperling H
AUTHOR: J Noldus J
AFFILIATION: Urologische Klinik, Universitätsklinikum, Essen. herbert.sperling@uni-essen.de
PUBTYPE: Journal Article
JOURNALTITLE: Der Urologe. Ausg. A.
COUNTRY: Germany
TITLE: [Prostate carcinoma and erectile dysfunction. Which therapy when?]
PUBDATE: 20031001
The quality of life of patients after radical prostatectomy is mainly influenced by erectile dysfunction (ED) and incontinence. New criteria for treatment and patient selection give us the opportunity to restore sexual function in more patients.When ED is present, we should not wait for 24 months for natural restitution. PDE-5-inhibitors, intracavernosal self injection therapy and the vacuum constriction device are effective and conform to both patient and economic preference.Therefore, every urologists should be able to offer his patients an individual and successful approach to the therapy of ED after prostate cancer.


10. DOCID:29929 SCORE: 0.00146041137257211
DOCNO: 12045431
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radionuclide imaging
QUALIFIER: secondary
QUALIFIER: radionuclide imaging
QUALIFIER: radionuclide imaging
QUALIFIER: radionuclide imaging
QUALIFIER: secondary
AUTHOR: John S Miliziano JS
AUTHOR: Yong C Bradley YC
AFFILIATION: Department of Nuclear Medicine, Brooke Army Medical Center, Ft. Sam, Houston, Texas 78234, USA. jmiliz@satx.rr.com
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical nuclear medicine.
COUNTRY: United States
TITLE: Soft tissue metastases and lung cancer recurrence detected by Tc-99m depreotide scintigraphy.
PUBDATE: 20020601
A 63-year-old woman with previously treated stage I lung cancer was reexamined 5 years later for recurrence. A conventional work-up using computed tomographic scanning and transbronchial biopsy showed nothing abnormal. A Tc-99m depreotide scan, however, led to a noninvasive diagnosis of lung cancer recurrence with metastases, and it directed a noninvasive tissue diagnosis.


11. DOCID:29945 SCORE: 0.00146041130529813
DOCNO: 12434705
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: drug effects
AUTHOR: Márta Alberth M
AUTHOR: Judit Török J
AUTHOR: Judit Nemes J
AUTHOR: Csongor Kiss C
AUTHOR: Ildikó Márton I
AFFILIATION: Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Fogorvostudományi Intézet.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Fogorvosi szemle.
COUNTRY: Hungary
TITLE: [Structural disorder of dental enamel caused by antineoplastic agents--case report]
PUBDATE: 20021001
Cancer is the second most common cause of mortality in childhood. Complex therapy decreases the rate of mortality, but chemotherapy and irradiation may, however, create acute and long-term side effects. Although immuno- and myelo-suppressive side effects of anti-neoplastic therapy are unavoidable, their detrimental impact on oral health can and should be avoided contributing to a better quality of life of these children.


12. DOCID:31915 SCORE: 0.0014122635489544
DOCNO: 12866565
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: physiology
AUTHOR: C Testorelli C
AFFILIATION: Dpt.of Pharmacology, School of Medicine, University of Milan, Milan, Italy. Carla.Testorelli@unimi.it
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of experimental & clinical cancer research : CR.
COUNTRY: Italy
TITLE: Telomerase and cancer.
PUBDATE: 20030601
Telomerase is a reverse transcriptase enzyme that can add the hexameric repeats TTAGGG to chromosome ends. So far, telomerase prevents telomere erosion occurring during cell division, because of the semi-conservative DNA replication. The maintenance of telomeres length is necessary for the proliferation of cells and may represent a critical step both in senescence and cancer progression. Telomerase is present in most types of tumors, but usually not in normal somatic cells. This review will focus on the possibility of exploiting telomerase as a marker for cancer diagnosis and prognosis and as an ideal target for cancer therapies based on telomerase inhibitors.


13. DOCID:31739 SCORE: 0.00141097634419051
DOCNO: 16210955
OWNER: NLM
STATUS: In-Process
AUTHOR: Nicolas A Muruve NA
AUTHOR: Daniel A Shoskes DA
AFFILIATION: Department of Urology and Kidney Transplantation, Cleveland Clinic Florida, Weston, FL 33332, USA. muruven@ccf.org
PUBTYPE: Journal Article
JOURNALTITLE: Transplantation.
COUNTRY: United States
TITLE: Genitourinary malignancies in solid organ transplant recipients.
PUBDATE: 20050901
Malignancy is a recognized complication of transplantation. Genitourinary cancers are the second most common tumors in transplant recipients with prostate cancer and renal cell carcinoma the most common. Unlike the more common skin malignancies, genitourinary tumors have a significant impact on both graft and patient survival. Surgical and radiation treatments need to consider the location of heterotopic transplants and administration of chemotherapy may need alteration in light of immunosuppression being used. The major genitourinary malignancies and their management will be reviewed in this article with emphasis on the concerns that arise in a transplant recipient.


14. DOCID:31716 SCORE: 0.0014109760630412
DOCNO: 14554241
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Delivery of Health Care
DESCRIPTOR: Nurse's Role
QUALIFIER: nursing
AUTHOR: Jessica Corner J
AFFILIATION: School of Nursing and Midwifery, University of Southampton, Highfield, UK. J.L.Corner@soton.ac.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The lancet oncology.
COUNTRY: England
TITLE: The role of nurse-led care in cancer management.
PUBDATE: 20031001
Extending nurses' roles and responsibilities so that they may take on some functions of doctors is widely advocated to assist with shortages of medical staff, improve service provision, and to reduce costs. In cancer care in particular, use of specialist nurses to help meet targets for faster diagnosis and treatment is seen as essential. However, there has been little detailed investigation of the consequences, effectiveness, or acceptability of doctor-nurse substitution across health care, or more specifically in cancer services. In this article, I review the evidence for nurse-led care in cancer.