0. DOCID:27780 SCORE: 0.00305507307074491
DOCNO: 11382941
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Clinical Trials
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: diagnosis
AUTHOR: T B Julian TB
AFFILIATION: Division of Surgical Oncology, Western Pennsylvania Allegheny Health System, Pittsburgh, PA 15212, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of magnetic resonance imaging : JMRI.
COUNTRY: United States
TITLE: MRI: a role in clinical trials.
PUBDATE: 20010601
The diagnosis and treatment of breast cancer has evolved significantly over the last 20 years. Breast-conserving therapy is replacing the Halstedian concept of "en bloc" resection. Difficulties in detection, pre- and postoperative planning and follow up continue to challenge the clinician. Women at high risk present a significant clinical dilemma. MRI technology in many of these areas is providing more information about detection, tumor size, extent, and response to treatment. The careful and thoughtful inclusion of MRI in clinical trials may help continue the advancement of breast cancer care. J. Magn. Reson. Imaging 2001;13:837-841.
1. DOCID:26906 SCORE: 0.00225476360549229
DOCNO: 11578733
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Brachytherapy
QUALIFIER: radiation effects
QUALIFIER: radiotherapy
AUTHOR: A M Olszewska AM
AUTHOR: A E Saarnak AE
AUTHOR: R W de Boer RW
AUTHOR: B N van Bunningen BN
AUTHOR: M J Steggerda MJ
AFFILIATION: Medical Physics Department, M. Sklodowska-Curie Memorial Cancer Center, W.K. Roentgen 5, 02-781, Warsaw, Poland.
PUBTYPE: Journal Article
JOURNALTITLE: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
COUNTRY: Ireland
TITLE: Comparison of dose-volume histograms and dose-wall histograms of the rectum of patients treated with intracavitary brachytherapy.
PUBDATE: 20011001
The correlation between dose values from dose-volume histograms (DVHs) and dose values from dose-wall histograms (DWHs) of the rectum tissue of patient with uterine cervix cancer was determined. The minimum dose in 2 cm3 in the high-dose region of the DVH is a good estimate of the dose in the rectum wall.
2. DOCID:26679 SCORE: 0.00180649894988845
DOCNO: 10505782
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: methods
AUTHOR: G J Whitman GJ
AFFILIATION: Division of Diagnostic Imaging, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA. gwhitman@di.mdacc.tmc.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: The role of mammography in breast cancer prevention.
PUBDATE: 19990901
Screening mammography has been shown to reduce breast cancer mortality by detecting small, nonpalpable, early-stage breast cancers. In 1998, several studies were published, reinforcing the value of screening mammography in women aged 40 years and older. Some studies focused on when screening should begin (age 40 years), while others analyzed the process of screening mammography, with particular attention to recall rates and false-positive studies. Other reports emphasized the limitations of mammographic interpretation, the use of computers to aid in mammographic diagnosis, and screening with ultrasound.
3. DOCID:27660 SCORE: 0.00177689849669304
DOCNO: 11226765
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: S Mercadante S
AUTHOR: R K Portenoy RK
AFFILIATION: Anesthesia and Intensive Care Unit & Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Palermo, Italy.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of pain and symptom management.
COUNTRY: United States
TITLE: Opioid poorly-responsive cancer pain. Part 1: clinical considerations.
PUBDATE: 20010201
Pain that is poorly responsive to opioid analgesics is challenging for physicians who deal with cancer patients. Numerous factors may influence analgesic response during the course of the illness. These include changing nociception associated with disease progression, the appearance of intractable side effects, the development of tolerance, the presence of neuropathic pain, the temporal pattern, the effects produced by the production of opioid metabolites, and many others. These factors influence the delicate balance between pain relief and opioid toxicity that must be achieved in cancer patients with pain.
4. DOCID:27066 SCORE: 0.00164417514827824
DOCNO: 10704709
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiation effects
QUALIFIER: radiation effects
QUALIFIER: innervation
QUALIFIER: radiotherapy
AUTHOR: P Y Khaw PY
AUTHOR: D L Ball DL
AFFILIATION: Division of Radiation Oncology, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St., Melbourne, Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Lung cancer (Amsterdam, Netherlands)
COUNTRY: IRELAND
TITLE: Relief of non-metastatic shoulder pain with mediastinal radiotherapy in patients with lung cancer.
PUBDATE: 20000401
Three patients with lung cancer and shoulder pain for which no local cause could be found are described. All three benefited from a course of palliative radiotherapy to ipsilateral mediastinal disease remote from the site of the pain. It is suggested that the pain is referred from intrathoracic involvement of the phrenic nerve by cancer, and that palliative irradiation of the mediastinum should be considered if investigations fail to reveal a local cause for ipsilateral shoulder pain.
5. DOCID:26273 SCORE: 0.00157862615303708
DOCNO: 11883291
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: diagnosis
AUTHOR: J Dudkiewicz J
AUTHOR: M Muszer M
AFFILIATION: Katedry i Kliniki Ginekologii SLAM w Zabrzu.
PUBTYPE: Journal Article
JOURNALTITLE: Ginekologia polska.
COUNTRY: Poland
TITLE: [Diagnostic procedures of pathological bleeding in women population: comparison of hysteroscopy, ultrasonography and microscopic examination endometrium]
PUBDATE: 20011201
The goal of this study was to asses the diagnostic value of hysteroscopy, cytology, ultrasonography and histopathology in various pathological states in endometrium. 250 patients with abnormal uterine bleeding were examined. The wide range of several diagnoses were achieved with 8 cases of cancer. Used methods were found to be complementary because 7 cases of cancer were recognised by histopathologic method, 6 by hysteroscopy and 5 by a cytological test (3 results were suspicious). To the risk group were qualified by ultrasonography all patients in postmenopausal age.
6. DOCID:25673 SCORE: 0.00157482597526407
DOCNO: 11008235
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: methods
QUALIFIER: pathology
QUALIFIER: analysis
AUTHOR: P E Bernick PE
AUTHOR: W D Wong WD
AFFILIATION: Colorectal Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Staging: what makes sense? Can the pathologist help?
PUBDATE: 20001001
The staging of colorectal cancer continues to be an interesting and evolving process. Accurate staging can predict overall prognosis and helps to select appropriate treatment options. This article addresses the clinical and pathologic staging of colon and rectal cancer. The use of endorectal ultrasound in the preoperative clinical staging of rectal cancer is reviewed. The importance of surgical resection margins, lymph node retrieval rates, and tumor markers is discussed.
7. DOCID:27580 SCORE: 0.0015713537078196
DOCNO: 10528896
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
AUTHOR: A J Markowitz AJ
AUTHOR: S J Winawer SJ
AFFILIATION: Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: Screening and surveillance for colorectal cancer.
PUBDATE: 19991001
Colorectal cancer is the second most common cause of cancer death among American men and woman. Currently available screening and surveillance techniques are effective in detecting early-stage colorectal cancer and its premalignant precursor lesion, the adenomatous polyp (adenoma). Removal of adenomas by colonoscopic polypectomy significantly reduces the incidence of colorectal cancer. Appropriate screening and surveillance recommendations should be based on the individual's colorectal cancer risk stratification. High-risk groups, such as patients with hereditary nonpolyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP), should be offered genetic counseling and specialized screening recommendations for colorectal and associated extracolonic malignancies.
8. DOCID:27636 SCORE: 0.00157135277300397
DOCNO: 10619520
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: W T Sause WT
AFFILIATION: LDS Hospital, Radiation Center, Salt Lake City, UT 84143, USA. ldwsause@ihc.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: The role of radiotherapy in non-small cell lung cancer.
PUBDATE: 19991201
Most patients who receive a diagnosis of non-small cell lung cancer (NSCLC) have advanced disease and are not curable with surgery. Developments in the technology of radiation therapy (RT) have contributed to the broad utility of this treatment modality in both a curative and palliative capacity. Many patients at all stages, including those who are medically inoperable, may benefit from RT. Locally advanced NSCLC is treated commonly with combined modality therapy. Novel RT administration schedules and chemotherapy regimens for combined modality therapy are essential for improving the management of NSCLC. Additional benefits can be foreseen as new strategies for patient selection emerge.
9. DOCID:27279 SCORE: 0.00154130684679153
DOCNO: 10688873
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: prevention & control
AUTHOR: M B Sporn MB
AUTHOR: N Suh N
AFFILIATION: Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, USA. michael.b.sporn@dartmouth.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Carcinogenesis.
COUNTRY: ENGLAND
TITLE: Chemoprevention of cancer.
PUBDATE: 20000301
In this short article, we review the conceptual basis for chemoprevention of cancer, the proven clinical efficacy of this concept, and current trends to develop new chemopreventive agents based on understanding of their mechanisms of action. Four classes of new agents, namely selective inhibitors of cyclooxygenase-2, selective estrogen receptor modulators, rexinoids (retinoids that bind selectively to the receptors known as RXRs) and ligands for the peroxisome proliferator-activated receptor-gamma are discussed in detail. The importance of developing totally new classes of chemopreventive agents is stressed, with particular emphasis on the potential usefulness of new synthetic triterpenoids derived from naturally occurring molecules.
10. DOCID:24779 SCORE: 0.00152806093411048
DOCNO: 11806679
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nurse's Role
DESCRIPTOR: Oncologic Nursing
QUALIFIER: organization & administration
QUALIFIER: manpower
QUALIFIER: manpower
QUALIFIER: organization & administration
AUTHOR: S Woodhouse S
AUTHOR: P Smith P
AFFILIATION: Birmingham Children's Hospital NHS Trust, UK.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer care.
COUNTRY: England
TITLE: A lead cancer nurse role at Birmingham Children's Hospital National Health Service Trust.
PUBDATE: 20011201
This paper reports on an innovative scheme and course developed as part of a Lead Cancer Nurse role based at the Birmingham Children's Hospital NHS Trust, UK. In doing so issues are raised which may be helpful to others should they consider adopting a similar scheme and the possibilities of the scope of the role are highlighted.
11. DOCID:26275 SCORE: 0.0015150113636466
DOCNO: 11764713
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Attitude to Health
DESCRIPTOR: Interpersonal Relations
DESCRIPTOR: Life Change Events
QUALIFIER: psychology
QUALIFIER: psychology
AUTHOR: M L Vachon ML
AFFILIATION: Departments of Psychiatry and Public Health Sciences, the University of Toronto, Ontario, Canada.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology nursing.
COUNTRY: United States
TITLE: The meaning of illness to a long-term survivor.
PUBDATE: 20011101
OBJECTIVES: To review the ways in which cancer survivors find meaning in their illness experiences. DATA SOURCES: Research literature and professional and personal experiences. CONCLUSIONS: Survivors confront a number of issues as they try to find a place for their cancer experience in their lives and adopt different approaches to cope with their survivorship. IMPLICATIONS FOR NURSING PRACTICE: Nurses can assist cancer survivors to find meaning in their illness experience by understanding the symptoms and issues associated with survival.
12. DOCID:25689 SCORE: 0.00150807485207218
DOCNO: 10205289
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M Fleischhacker M
AUTHOR: T Beinert T
AFFILIATION: Medizinische Klinik m.S., Hämatologie und Onkologie, Charité, Campus Mitte, Schumannstr. 20/21, D-10117 Berlin, Germany. michael.fleischhacker@charite.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of medical research.
COUNTRY: GERMANY
TITLE: Tumour markers - new aspects of an old discussion?
PUBDATE: 19990401
The knowledge about the molecular genetic features of cancer has been vastly increased within the last few years. Tumor markers used so far for diagnosis, monitoring, and follow-up of cancer patients are tumor-associated rather than tumor-specific. Therefore, the development of more sensitive and specific tumor markers is urgently needed. In this review, the possibilities of using molecular genetic characteristics of cancer as specific and sensitive tumor markers are discussed.
13. DOCID:27582 SCORE: 0.0014853573840875
DOCNO: 10482182
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Antigens, Surface
DESCRIPTOR: Tumor Markers, Biological
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: D Daliani D
AUTHOR: C N Papandreou CN
AFFILIATION: University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: Markers of androgen-independent progression of prostatic carcinoma.
PUBDATE: 19990801
Prostate cancer (PCa) remains the most common cancer and the second leading cause of cancer mortality in men in the United States. The evolution from a localized to a metastatic phenotype coupled with the progression from an androgen-dependent (AD) to an androgen-independent (AI) state leads to a universally fatal disease. Identifying the biologic characteristics associated with PCa progression is a major goal of current research efforts by different groups, in the hope to better predict the natural history of the disease in an individual patient and to design treatments based on the specific biologic behavior.
14. DOCID:26003 SCORE: 0.00146260808187064
DOCNO: 9536631
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Estrogen Replacement Therapy
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: C A Bertelsen CA
AUTHOR: B Andreasson B
AFFILIATION: Gynaekologisk-obstetrisk afdeling, Amtssygehuset i Herlev.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Ugeskrift for laeger.
COUNTRY: DENMARK
TITLE: [Estrogen replacement to women treated for endometrial cancer]
PUBDATE: 19980301
Oestrogen replacement therapy in women treated for endometrial cancer has long been considered contra-indicated. Based on a review of the literature, which shows a low risk of recurrence during oestrogen replacement therapy in women treated for low-risk endometrial cancer, we advocate that this group of patients could be offered oestrogen replacement therapy and be provided with the benefits of prevention of cardiovascular disease and osteoporosis. Further studies are needed to investigate the survival and recurrence rates of high-risk patients treated with oestrogen replacement therapy.