0. DOCID:7721 SCORE: 0.00251387402674185
DOCNO: 508570
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Alcohol Drinking
QUALIFIER: adverse effects
QUALIFIER: mortality
AUTHOR: S Kono S
AUTHOR: M Ikeda M
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Correlation between cancer mortality and alcoholic beverage in Japan.
PUBDATE: 19790901
Geographical correlations between standardized, mortality ratios (SMRs) of cancers and consumption of different types of alcoholic beverages (saké synthetic saké, shochu, beer, wine, and whisky), of cigarettes, and urbanization were examined for all 46 prefectures in Japan. Suggestive correlations were observed between cancer of the oesophagus in males and both shochu and whisky (r = 0.27 and 0.22 respectively), between cancer of the rectum in males and wine (r = 0.45), and between cancer of the prostate and shochu (r = 0.50). These correlations were also confirmed in the partial correlations between SMRs of cancers and consumption of alcoholic beverages, controlling for the two variables urbanization and consumption of cigarettes. Alhtough cancers of other sites were also correlated with certain types of alcoholic beverages, their associations seemed to be secondary to other factors. The validity of higher-order partial correlations and the problems of correlation study are also referred to.


1. DOCID:5705 SCORE: 0.00213938936373296
DOCNO: 7278725
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Diet
DESCRIPTOR: Plants, Medicinal
DESCRIPTOR: Seaweed
QUALIFIER: prevention & control
AUTHOR: J Teas J
PUBTYPE: Journal Article
JOURNALTITLE: Medical hypotheses.
COUNTRY: ENGLAND
TITLE: The consumption of seaweed as a protective factor in the etiology of breast cancer.
PUBDATE: 19810501
A review of the biological properties of seaweed is presented and the role of seaweed as a breast cancer anticarcinogen is suggested. Proposed mechanisms of action are: reduction of plasma cholesterol, binding of biliary steroids, inhibition of carcinogenic fecal flora, binding of pollutants, stimulation of the immune system, and the protective effects of beta-sitosterols. In an experiment using sarcoma-180 in mice, seaweed extract appeared to have an antitumor effect. Thus it is suggested that breast cancer may be prevented and that this dietary habit among the Japanese could be an important factor in understanding the lower breast cancer rates reported in Japan.


2. DOCID:4372 SCORE: 0.00184509895979942
DOCNO: 146867
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
DESCRIPTOR: Chromosome Disorders
QUALIFIER: genetics
AUTHOR: B R Elejalde BR
AUTHOR: J M Opitz JM
PUBTYPE: Journal Article
JOURNALTITLE: Postgraduate medicine.
COUNTRY: UNITED STATES
TITLE: Clinical cytogenetics: part 1.
PUBDATE: 19780201
This paper is an introduction to the cytogenetic biology of man. It deals with the role of chromosome abnormalities in prenatal death, malformation syndromes, mental retardation, malformation/mental retardation syndromes, abnormalities of sex determination, sex differentiation and sexual function, cancer, and certain genetic disorders in which chromosome abnormalities are seen commonly. Down syndrome is discussed as an important and common example of a malformation/mental retardation syndrome.


3. DOCID:7615 SCORE: 0.00176278840943321
DOCNO: 7020708
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: standards
AUTHOR: E E Pochin EE
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Atomic energy review.
COUNTRY: AUSTRIA
TITLE: Risk assessment for radiation protection purposes.
PUBDATE: 19800901
In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing other, 'non-stochastic', effects is not exceeded.


4. DOCID:7385 SCORE: 0.00172187678227314
DOCNO: 671663
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: H T Lynch HT
AUTHOR: P M Lynch PM
AUTHOR: R E Harris RE
PUBTYPE: Journal Article
JOURNALTITLE: JAMA : the journal of the American Medical Association.
COUNTRY: UNITED STATES
TITLE: Minimal genetic findings and their cancer control implications. A family with the cancer family syndrome.
PUBDATE: 19780801
A kindred in which five first-degree relatives were initially known to exhibit colorectal, endometrial, and unspecified carcinoma for two generations, occurring at an early age and including three cases of multiple primary cancer, is consistent with criteria for the cancer family syndrome. Follow-up included a diligent surveillance program that led to the early diagnosis of colon cancer in a young member of the third generation who had been considered at high risk for this lesion. Manifestly, hereditary cancer syndrome identification may be expedited through longitudinal study of apparently cancer-prone kindreds, given limited historical information about tumor expression. However, cancer surveillance measures can and should be instituted early and predicated on clues that suggest, but need not be diagnostic of, such a hereditary cancer predisposing disorder.


5. DOCID:5572 SCORE: 0.00161183639720617
DOCNO: 7281100
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: cytology
AUTHOR: F Hartveit F
PUBTYPE: Journal Article
JOURNALTITLE: Thorax.
COUNTRY: ENGLAND
TITLE: Time and place for sputum cytology in the diagnosis of lung cancer.
PUBDATE: 19810401
Despite ready access to medical care 91% of patients dying of lung cancer derived from a population of just under 400 000 are shown to have presented too late for other than palliative treatment. As the incidence and death rates from lung cancer in the district were very similar, few survivors can be expected. Morphological confirmation of the diagnosis was available in 96% of cases. The first positive morphological diagnosis was obtained from sputum cytology taken on admission in 69% of all cases and in 77% of those in whom there had been delay in diagnosis. More extensive use of this investigation on an outpatient basis is urged.


6. DOCID:7288 SCORE: 0.00154587988677975
DOCNO: 646395
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: R S Bart RS
AUTHOR: D Schrager D
AUTHOR: A W Kopf AW
AUTHOR: J Bromberg J
AUTHOR: N Dubin N
PUBTYPE: Journal Article
JOURNALTITLE: Archives of dermatology.
COUNTRY: UNITED STATES
TITLE: Scalpel excision of basal cell carcinomas.
PUBDATE: 19780501
A total of 468 coded, histologically proved basal cell carcinomas were excised from 446 patients in the Skin and Cancer Unit of New York University Medical Center from 1955 to 1967. The five-year cumulative recurrence rate was 6.8%. The highest recurrence rates, in areas in which sufficient data were available, were for the periocular regions, the scalp, and the nose and paranasal areas. Following re-treatment of recurrences, 464 of the 468 lesions (99.1%) were cured at the time of the most recent examination. After the second postoperative year, at least 70% of results were recorded as cosmetically good or excellent at the time of last follow-up. The most common complication was hypertrophic scars. There was a tendency for increasing incidence of such scars with increasing diameters of the lesions.


7. DOCID:6005 SCORE: 0.00147239247926684
DOCNO: 7451519
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Radiation Dosage
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: radiography
AUTHOR: A A De Smet AA
AUTHOR: S L Fritz SL
AUTHOR: M A Asher MA
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of bone and joint surgery. American volume.
COUNTRY: UNITED STATES
TITLE: A method for minimizing the radiation exposure from scoliosis radiographs.
PUBDATE: 19810101
The radiation exposure resulting from standard scoliosis radiographs was determined for eighteen adolescent girls. The risk of inducing breast cancer was estimated from the skin-exposure doses. The average skin exposure to the breasts was 59.6 millirads (0.59 mGy) for the anteroposterior radiograph. Assuming a total of twenty-two anteroposterior radiographs during a course of treatment, the cumulative exposure would result in a 1.35% relative increase in the risk of development of breast cancer. By utilizing collimation of the x-ray beam and proper selection of grids, films, and screens, the radiation risk of scoliosis radiographs is minimized.


8. DOCID:4685 SCORE: 0.00134016056692897
DOCNO: 7423370
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Surgical Flaps
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: R M Zuker RM
AUTHOR: R T Manktelow RT
AUTHOR: J A Palmer JA
AUTHOR: I B Rosen IB
PUBTYPE: Journal Article
JOURNALTITLE: Surgery.
COUNTRY: UNITED STATES
TITLE: Head and neck reconstruction following resection of carcinoma, using microvascular free flaps.
PUBDATE: 19801001
Our experience with 15 microvascular free-flap transfers is documented and discussed. We feel that the procedure is an effective means of reconstruction for complex and extensive defects. Rapid advances have been made in all areas of cancer surgery. It is important that these patients be afforded a speedy and, preferably, immediate reconstruction and rehabilitation. Conventional techniques do not satisfy all the required goals.


9. DOCID:5204 SCORE: 0.00133996314379186
DOCNO: 663262
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiography
QUALIFIER: radiotherapy
QUALIFIER: adverse effects
AUTHOR: C T Chung CT
AUTHOR: R H Sagerman RH
AUTHOR: G A King GA
AUTHOR: W S Yu WS
AUTHOR: J T Johnson JT
AUTHOR: C W Cummings CW
PUBTYPE: Journal Article
JOURNALTITLE: Radiology.
COUNTRY: UNITED STATES
TITLE: Complications of high dose preoperative irradiation for advanced laryngeal-hypopharyngeal cancer.
PUBDATE: 19780801
The authors studied 162 patients with advanced cancer of the laryngopharynx who were treated over the same period of time by standard techniques. High dose preoperative supervoltage irradiation to 5000 rads/5 weeks through large opposed lateral fields and a lower anterior neck field is not accompanied by a prohibitive increase in mortality or morbidity for patients with stage III-IV largynogopharyngeal cancer. Rescue surgery for recurrence after definitive irradiation can be accomplished.


10. DOCID:5253 SCORE: 0.00133781971865742
DOCNO: 7029291
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiation effects
QUALIFIER: prevention & control
QUALIFIER: prevention & control
AUTHOR: K Breur K
AUTHOR: O Schweisguth O
AUTHOR: P Cohen P
AUTHOR: P A Voûte PA
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: National Cancer Institute monograph.
COUNTRY: UNITED STATES
TITLE: Prophylactic irradiation of the lungs to prevent development of pulmonary metastases in patients with osteosarcoma of the limbs.
PUBDATE: 19810401
A controlled clinical trial conducted by the European Organization for Research on Treatment of Cancer Radiotherapy Cooperative Group has shown that prophylactic lung irradiation is effective in preventing lung metastases in patients under 17 years of age. Recently, a new three-armed trial has started in which prophylactic chemotherapy and lung irradiation and chemotherapy combined with radiotherapy to the lungs will be compared for their ability to prevent the development of lung metastases.


11. DOCID:4867 SCORE: 0.00128028954763904
DOCNO: 6929372
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cell Migration Inhibition
QUALIFIER: analysis
QUALIFIER: immunology
AUTHOR: S Matzku S
AUTHOR: M Zöller M
AUTHOR: U Schulz U
AUTHOR: W Dietze W
AUTHOR: H O Barth HO
AUTHOR: H D Saeger HD
AUTHOR: M R Price MR
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Lack of correlation between carcinoembryonic antigen content of tumor extracts and leukocyte migration reactivity of tumor patients.
PUBDATE: 19800601
Tumor extracts varying in carcinoembryonic antigen (CEA) content (0.4--2,280 ng/mg protein) did not affect the reactivity of cancer patients' leukocytes in the leukocyte migration inhibition test (LMIT). In addition, variations in the plasma CEA levels of tumor-bearing leukocyte donors did not influence the frequency of significant LMIT reactivity.


12. DOCID:6759 SCORE: 0.00126731565857721
DOCNO: 6781263
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tomography, X-Ray Computed
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: A A Mancuso AA
AUTHOR: D Maceri D
AUTHOR: D Rice D
AUTHOR: W Hanafee W
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: UNITED STATES
TITLE: CT of cervical lymph node cancer.
PUBDATE: 19810201
This study seeks to establish whether CT can accurately detect cancer in cervical lymph nodes. Retrospective correlation of CT scans and surgical findings in 51 patients with laryngeal cancer undergoing radical neck dissection suggested that the node-bearing areas in the neck can be usefully evaluated with CT scans. An additional 10 patients studied prospectively with carefully correlated CT scans and radical neck dissections were used to evaluate CT specific criteria for cancer in individual nodes. In 13 patients CT correctly predicted surgically confirmed nonpalpable nodal metastases in six. It suggested false-positive nodes in two. These criteria are now being tested in an ongoing evaluation of the clinical value of CT in the management of head and neck tumors.


13. DOCID:5285 SCORE: 0.00125693894621985
DOCNO: 6947924
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mother-Child Relations
DESCRIPTOR: Referral and Consultation
QUALIFIER: psychology
AUTHOR: Y Nir Y
AUTHOR: R S Pynoos RS
AUTHOR: J Holland J
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: General hospital psychiatry.
COUNTRY: UNITED STATES
TITLE: Cancer in a parent: the impact on mother and child. A consultation-liaison clinical case conference.
PUBDATE: 19811201
The following case presents a 31-year-old woman medically hospitalized during a relapse of acute myelocytic leukemia. A consultation-liaison clinical conference focused on the patient's concerns about the effects of her illness on her relationship with her young daughter and its impact on the child's development. The discussion illustrates the consultation-liaison psychiatrist's role in alerting parents to their child's needs and in providing them with tools for effective parenting in a crisis situation such a cancer.


14. DOCID:6417 SCORE: 0.00124086672905104
DOCNO: 6157059
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: diagnosis
QUALIFIER: analysis
QUALIFIER: diagnosis
AUTHOR: M A Muñóz Navas MA
AUTHOR: J A Amiguet JA
AUTHOR: F Conchillo F
AUTHOR: P Liso P
PUBTYPE: Journal Article
JOURNALTITLE: Medicina clínica.
COUNTRY: SPAIN
TITLE: [Haptoglobin in the biological diagnosis of gastric cancer (author's transl)]
PUBDATE: 19800701
Serum haptoglobin has been determined in a series of 69 patients with metastatic and non-metastatic gastric cancer. In both circumstances a marked increase of haptoglobin levels in comparison to the results in the control group was observed. A significant decrease was noticed in the presence of liver metastasis. Total alpha 2-globulin levels were also high in this patients, but a significant decrease was not observed in cases with liver metastasis. There was no parallelism between the values of haptoglobin and total alpha 2-globulins. The usefulness of these results in the diagnosis and prognosis of gastric cancer is stressed. Radial immunodiffusion using immunoserum anti-haptoglobin 1-1 is the technique of choice.