0. DOCID:11832 SCORE: 0.00333017580150736
DOCNO: 6498670
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tobacco Smoke Pollution
QUALIFIER: analysis
AUTHOR: N E Collishaw NE
AUTHOR: J Kirkbride J
AUTHOR: D T Wigle DT
PUBTYPE: Journal Article
JOURNALTITLE: Canadian Medical Association journal.
COUNTRY: CANADA
TITLE: Tobacco smoke in the workplace: an occupational health hazard.
PUBDATE: 19841101
Tobacco smoke, which contains over 50 known carcinogens and many other toxic agents, is a health hazard for nonsmokers who are regularly exposed to it while at work. Involuntary exposure to tobacco smoke annoys and irritates many healthy nonsmokers. Serious acute health effects are probably limited to the one fifth of the population with pre-existing health conditions that are aggravated by exposure to tobacco smoke. The consequences of long-term exposure include decreased lung function and lung cancer. Existing air quality standards for workplaces do not directly specify an acceptable level for tobacco smoke. The evidence on the composition of tobacco smoke and on the health hazards of involuntary exposure suggests that there may not be a "safe" level for such exposure.

1. DOCID:8644 SCORE: 0.0027966723669138
DOCNO: 6361201
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Automobile Driving
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: R Balarajan R
PUBTYPE: Journal Article
JOURNALTITLE: Journal of epidemiology and community health.
COUNTRY: ENGLAND
TITLE: Malignant lymphomas in road transport workers.
PUBDATE: 19831201
The relative risks of malignant lymphomas among road transport workers were investigated using the National Cancer Registry in England and Wales. Drivers of buses and coaches (OCC unit 120) had increased risks for both Hodgkin's and non-Hodgkin's lymphomas and the drivers of other road passenger vehicles (OCC unit 121) for Hodgkin's lymphomas only. Although the increased risks did not show statistical significance, they corresponded to and reinforced previously described findings based on occupational mortality.

2. DOCID:10063 SCORE: 0.00267059862812483
DOCNO: 6189199
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
AUTHOR: P D van Helden PD
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Interferon--the clinical experience.
PUBDATE: 19830501
Recent trials with interferon, in particular those using pure, recombinant interferon, have provided us with improved data (compared with those obtained in early studies) and show that interferon does hold some promise as a therapeutic agent. When used in the treatment of viral disease, interferon has shown itself to be quite effective in reducing viral titres. While not as effective against cancer, interferon has limited tumour growth, reduced the appearance of metastases and led to a general improvement in patient condition in many cases. This article discusses some of the recent results obtained with interferon in the treatment of viral disease and cancer.

3. DOCID:10949 SCORE: 0.00262150080543097
DOCNO: 6697299
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ear, Middle
QUALIFIER: epidemiology
AUTHOR: R P Morton RP
AUTHOR: P M Stell PM
AUTHOR: P P Derrick PP
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Epidemiology of cancer of the middle ear cleft.
PUBDATE: 19840401
Cancer of the middle ear is an uncommon tumor which has a very poor prognosis. A population-based analysis shows that there are two marked differences between men and women for middle ear cancer in England and Wales: (1) the incidence rate in men continues to rise with advancing age, but in women the rise is proportionately much less after 75 years of age; and (2) the mortality rate in men decreases after 70 to 75 years of age, whereas the mortality for women continues to rise with advancing age. The significance of these differences is not yet clear. No other epidemiologic reports related to middle ear cancer has been found in the literature.

4. DOCID:11897 SCORE: 0.00256955297055701
DOCNO: 6472068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: physiopathology
QUALIFIER: adverse effects
AUTHOR: A M D'iakova AM
AUTHOR: N V Stefani NV
AUTHOR: V G Andreev VG
AUTHOR: V V Pavlov VV
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Kidney function during radiosensitization with metronidazole]
PUBDATE: 19840801
Renal function was studied in patients with laryngeal cancer during radiation therapy performed under the conditions of mean fractionation in the presence of metronidazole radiosensitization up to the summary focal dose of 20 Gy. As compared to the findings before treatment an increase in the level of residual nitrogen, urea, uric acid and a decreased amount of creatinine in the plasma were noted. Decreased clearance of the urea, elevated Ambard's urosecretory constant were observed. The nature of these shifts was preserved even after the termination of subsequent radiation therapy up to the summary focal dose of 32 Gy without using the radiosensitogen. There is a possibility of a direct toxic effect of metronidazole on the renal tissue regardless of the state of oxygenation.

5. DOCID:9035 SCORE: 0.00243063831525544
DOCNO: 4067207
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Thyroidectomy
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: adverse effects
AUTHOR: N Panza N
AUTHOR: M De Rosa M
AUTHOR: G Lombardi G
AUTHOR: M Salvatore M
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of endocrinological investigation.
COUNTRY: ITALY
TITLE: Pseudotumor cerebri and thyroid-replacement therapy in patients affected by differentiated thyroid carcinoma.
PUBDATE: 19850801
The pseudotumor cerebri, a neurological syndrome clinically characterized by headaches, vomiting and bilateral papilledema, occurred in two patients, previously subjected to total thyroidectomy for differentiated thyroid carcinoma, after initiation of levothyroxine replacement therapy. In patients with thyroid cancer, subjected to thyroidectomy and then thyroid hormone replacement therapy, the possible development of pseudotumor cerebri syndrome should be considered and differentiated from CNS symptoms due to brain metastases.

6. DOCID:9982 SCORE: 0.00241758800444899
DOCNO: 3863580
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: classification
QUALIFIER: methods
AUTHOR: R J Black RJ
PUBTYPE: Journal Article
JOURNALTITLE: The Australian and New Zealand journal of surgery.
COUNTRY: AUSTRALIA
TITLE: Head and neck cancer staging systems: a comparison between UICC and AJC.
PUBDATE: 19850601
Two major TNM classification systems are currently in use for staging cancer of the head and neck region, i.e. UICC and AJC. This causes confusion when attempting to exchange information and evaluate treatment results between Australia and certain overseas centres. The two systems are described and the effect of any differences on altering survival data is assessed by reviewing 234 cases of squamous carcinoma of the larynx, hypopharynx, oropharynx and oral cavity. The direct correlation between the two systems is established. Shortcomings of the systems are demonstrated and important variables not included in either TNM system are discussed.

7. DOCID:8660 SCORE: 0.00241267177286642
DOCNO: 4063675
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
AUTHOR: G H Whitehouse GH
AUTHOR: S J Leinster SJ
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of radiology.
COUNTRY: ENGLAND
TITLE: The variation of breast parenchymal patterns with age.
PUBDATE: 19850401
The Wolfe classification of mammographic parenchymal patterns has been applied to 9036 women attending a Breast Cancer Screening Unit. Overall, two thirds fell into high risk categories (P2 and DY). The incidence of DY decreases with age, while the low risk categories (N1 and P1) increase with age. P2 remains constant over most of the age range. The implications of these findings are discussed and comparison is made with other series.

8. DOCID:8814 SCORE: 0.00240101185124763
DOCNO: 6350966
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: P Polterauer P
AUTHOR: F Meisl F
AUTHOR: J Funovics J
AUTHOR: J H Holzner JH
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Onkologie.
COUNTRY: SWITZERLAND
TITLE: [Early carcinoma of the stomach. Observations of the course over 23 months. A case report]
PUBDATE: 19830601
A case of an early cancer of the stomach is reported, in which the development of the lesion could be followed by repeated biopsies. Because of a high cardial risk of the patient, the tumor was resected as late as 23 months after the first diagnosis. During this time the lesion changed from a borderline lesion into an early cancer with penetration into the submucosa.

9. DOCID:11392 SCORE: 0.00233865279063011
DOCNO: 6415298
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Blood Transfusion, Autologous
QUALIFIER: surgery
QUALIFIER: therapy
AUTHOR: D A Swanson DA
AUTHOR: R K Lo RK
AUTHOR: B Lichtiger B
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Predeposit autologous blood transfusions in patients undergoing irradiation and radical cystectomy.
PUBDATE: 19831101
We have used blood withdrawn electively and frozen for later use by the donor in 25 patients with bladder cancer who were treated by preoperative irradiation and radical cystectomy. Patients donated 1 to 5 units of blood (average 3.4 per patient). We transfused 10 patients with only autologous blood, whereas 15 required some homologous blood in addition to their own banked blood. The program was well tolerated and repeated blood donation did not compromise the effectiveness of preoperative irradiation. Our preliminary data show that this program reduces the dependence on volunteer donor homologous blood transfusions for cystectomy, thus, decreasing the potential risk of an adverse reaction and avoiding seasonal blood bank shortages.

10. DOCID:11610 SCORE: 0.00230803518872659
DOCNO: 6507374
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Aclarubicin
QUALIFIER: analogs & derivatives
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: J A Kish JA
AUTHOR: M Al-Sarraf M
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Aclacinomycin. Phase II evaluation in advanced squamous carcinoma of the head and neck.
PUBDATE: 19841001
Aclacinomycin-A was evaluated in a phase II trial for advanced head and neck cancer. A weekly infusion of 65 mg/m2 was used. Eighteen patients were entered. Fifteen patients were evaluable for response and toxicity. One was evaluable for toxicity only and two died before completion of a full course of therapy. One patient without previous chemotherapy achieved a PR in a neck node for a short time. Six patients had stable disease with a median to progression of 6 weeks. Major toxicity encountered was bone marrow suppression. Aclacinomycin-A appears to have no activity in squamous cancer of the head and neck.

11. DOCID:11900 SCORE: 0.00228137675530766
DOCNO: 6087258
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: J Hayman J
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Pathology.
COUNTRY: AUSTRALIA
TITLE: Carcinoma of the urachus.
PUBDATE: 19840401
Two cases of carcinoma of the urachus are reported, 1 involving the dome of the bladder and 1 occurring beneath the peritoneum of the anterior abdominal wall below the umbilicus at the apex of an elongated bladder. Both patients died shortly after diagnosis, a fact which emphasizes the poor prognosis of this group of patients. The poor prognosis and need for more than local resection of the tumour may not be widely appreciated. Tumours arising above the bladder have a different mode of presentation from those arising within the bladder wall. Bladder wall tumours are most frequently mucus-secreting adenocarcinomas; tumours arising above the bladder may be more variable in their histological type, and include squamous and undifferentiated cancer. A simple classification into vesicle and supra-vesical tumours is proposed, to replace an early classification into 7 groups.

12. DOCID:10445 SCORE: 0.0022270735895851
DOCNO: 7200827
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: D L Citrin DL
AUTHOR: T F Hogan TF
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: A phase II evaluation of adriamycin and cis-platinum in hormone resistant prostate cancer.
PUBDATE: 19820701
Twenty-five patients with metastatic prostate cancer were treated with a combination of Adriamycin 50 mg/m2 and cis-platinum (CDDP) 50 mg/m2 every three weeks. Response was evaluated using radioisotope bone scan, serum acid phosphatase levels, and clinical status. Response rates of 6% bone, 21% acid phosphatase, and 24% clinical status were noted. Major toxicity was gastrointestinal (due to CDDP). Treatment was well tolerated even in patients with extensive bone metastases and prior irradiation. Using the response criteria described here, patients with metastatic prostate cancer without measurable soft tissue disease are eligible for Phase II and III study.

13. DOCID:11565 SCORE: 0.00214380211395104
DOCNO: 6925592
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: instrumentation
QUALIFIER: therapy
AUTHOR: J Scheiblich J
AUTHOR: O Petrowicz O
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of microwave power.
COUNTRY: CANADA
TITLE: Radiofrequency-induced hyperthermia in the prostate.
PUBDATE: 19820901
A high frequency radiator has been developed for the treatment of prostate cancer by hyperthermia. The applicator produces a deep seated hot spot. The radiator has an outer diameter of 20 mm and an insertable length of about 175 mm. A high frequency cylindrical slot antenna inside the applicator is cooled by water. The frequency used is 433.9 MHz, one of the frequencies allowed for medical therapy in the F.R.G. A control system regulating the power output of the radiator avoids damage to the tissue around the prostate, especially the rectum mucosa and the tissue between rectum and prostate. About 60 experiments with male dogs proved that local heating of the prostate is possible with the help of the developed applicator without any damage in the surrounding tissue.

14. DOCID:11350 SCORE: 0.00213713925411144
DOCNO: 6084969
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: G L Wied GL
AUTHOR: M Bibbo M
AUTHOR: F T Pishotta FT
AUTHOR: P H Bartels PH
PUBTYPE: Journal Article
JOURNALTITLE: Analytical and quantitative cytology.
COUNTRY: UNITED STATES
TITLE: Intermediate cell markers for malignancy. Consistency of expression.
PUBDATE: 19841201
Studies of samples from a larger patient population confirmed the consistency of expression of the previously reported markers for malignancy in normal-appearing intermediate cervical cells in samples from patients with abnormal cytology (moderate dysplasia and severe dysplasia/carcinoma in situ). Based on samples of only 30 cells per case, a false-negative rate of 10% to 30% was estimated. The expression of the marker features thus provides a clear indication of uterine abnormal cytology; the lack of expression, however, does not entirely rule out the possibility of uterine abnormalities. The use of larger sample sizes and better staining protocols could further enhance the usefulness of marker feature studies in the prescreening for cancer.