0. DOCID:7122 SCORE: 0.00429076883069997
DOCNO: 418978
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: G L Pride GL
AUTHOR: A E Schultz AE
AUTHOR: T W Chuprevich TW
AUTHOR: D A Buchler DA
PUBTYPE: Journal Article
JOURNALTITLE: Obstetrics and gynecology.
COUNTRY: UNITED STATES
TITLE: Primary invasive squamous carcinoma of the vagina.
PUBDATE: 19790201
Forty-three cases of primary vaginal squamous cell cancer were treated at the University of Wisconsin Hospital between 1956 and 1971. These cases comprised 1.2% of patients admitted to the University Hospital with female genital tract cancer. Evidence is presented to support a modification of the currently accepted FIGO staging system for vaginal carcinoma (Stage II disease). Radiation therapy using both external beam and brachyradium equivalents or interstitial implantation of suitable isotopes was an effective method for the treatment of patients having early and locally advanced invasive vaginal cancer. The 5-year absolute survival rate for the entire series was 37.2%. Absolute survival rate by modified FIGO clinical staging was 66% for Stages I and IIA, 31% for Stage IIB, 25% for Stage III, and 0% for Stage IV.


1. DOCID:4598 SCORE: 0.00320468601411046
DOCNO: 7306923
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: S Lodrini S
AUTHOR: M Savoiardo M
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Metastases of carcinoma to intracranial meningioma: report of two cases and review of the literature.
PUBDATE: 19811201
Two cases of metastases from carcinoma to intracranial meningioma are presented. In the first case the presence of the malignant tumor was unsuspected at the time of intracranial operation. In the second case, a breast cancer had been previously removed, and unusual cranial computed tomographic findings were noted. The literature on metastases to intracranial tumors is reviewed, and the association of meningioma and carcinoma of the breast is emphasized.


2. DOCID:4621 SCORE: 0.00294751388833463
DOCNO: 740287
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
AUTHOR: D Fritze D
AUTHOR: J Fritze J
AUTHOR: M Kaufmann M
AUTHOR: P Drings P
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Immunodiagnostic aspects of breast cancer. The phenomenon of leukocyte adherence inhibition]
PUBDATE: 19781101
In 39 patients with breast cancer and in 38 female controls the leucocyte adherence was tested in glass tubes in the presence of a series of extracts of breast cancer and control tissues. It was shown that the adherence of leucocytes of patients with operable carcinoma of the breast (stage I/II) is selectively inhibited by extracts from breast cancer tissues. Leucocyte adherence inhibition tests could thus become important for immunodiagnostics.


3. DOCID:6688 SCORE: 0.00287767049354424
DOCNO: 87268
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: J K Willson JK
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Pulmonary toxicity of antineoplastic drugs.
PUBDATE: 19781201
Drug-induced pulmonary disease is an infrequent, but clinically significant, toxic manifestation of antineoplastic drug therapy. Pulmonary toxicity has been associated primarily with bleomycin therapy but also has been described with busulfan, cyclophosphamide, methotrexate, and the nitrosoureas. Cytotoxic drug-induced pulmonary disease is characterized by an insidious and nonspecific presentation. The common pathologic process of a fibrosing alveolitis follows a variety of toxic mechanisms associated with the chemotherapeutic agents. The importance of close clinical monitoring is emphasized by the necessity for early withdrawal of the drug in order to halt or reverse potentially lethal pulmonary disease. At the same time, the nonspecific nature of the lung disease and the multitude of potential insults to the lung in a cancer patient make an early aggressive evaluation mandatory. A lung biopsy is almost always indicated.


4. DOCID:7666 SCORE: 0.00286617624701739
DOCNO: 7000060
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunity, Cellular
DESCRIPTOR: Immunologic Techniques
DESCRIPTOR: Leukocyte Adherence Inhibition Test
QUALIFIER: immunology
AUTHOR: M Winter M
AUTHOR: D S Nelson DS
AUTHOR: G W Milton GW
PUBTYPE: Journal Article
JOURNALTITLE: Australian and New Zealand journal of medicine.
COUNTRY: AUSTRALIA
TITLE: Leucocyte adherence inhibition test for the detection of cell-mediated immunity to malignant melanoma.
PUBDATE: 19800801
A tube leucocyte adherence test was used to detect reactivity of melanoma patients to extracts of melanoma tissue. Breast cancer extracts were used as a control. Of 31 melanoma patients 22 gave a positive reaction (non-adherence index > 25%) to melanoma extracts whereas only three of 24 normal subjects did so. Fifteen of 16 patients with Stage 1 melanoma reacted but only seven of 15 patients with Stage 2 or Stage 3 disease did so. None of seven patients with breast cancer reacted to melanoma extract, but four of them reacted to breast cancer extract. None of four patients with benign breast disease reacted to either extract. It is concluded that leucocyte adherence inhibition is potentially useful in investigations of tumour-specific immune reactivity to melanoma and of melanoma antigens.


5. DOCID:7144 SCORE: 0.0028591775219598
DOCNO: 7272978
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Physicians, Family
QUALIFIER: diagnosis
AUTHOR: P A Williams PA
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The responsibility of the family physician in the detection of gynecologic cancer.
PUBDATE: 19810701
The family physician's role in health maintenance and preventive medicine places him or her in a unique position in providing care for the gynecologic patient. Illness as well as health has been a traditionally matriarchal responsibility and therefore places the woman at risk for gynecologic cancer in contact with her family physician at a greater frequency than other specialties. Caring for the family's health needs should be used as an opportunity for the physician and the patient to discuss her own personal health care needs, which include those in the field of gynecology. Family physicians will not provide definitive treatment for major gynecologic malignancies; however physicians must know the best referral opportunities available to the patient and to the consultant. The family physician must further be able and willing to reassume follow-up care after definitive therapy has been effected.


6. DOCID:5661 SCORE: 0.00274861654118513
DOCNO: 7016298
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: R Hoover R
AUTHOR: J F Fraumeni JF
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Drug-induced cancer.
PUBDATE: 19810301
This report reviews the medicinal agents that have been linked to human cancer, with emphasis on recent evidence implicating estrogenic compounds such as DES, menopausal estrogens, and oral contraceptives. Attention is also given to drugs that have fallen under suspicion and requires further epidemiologic evaluation. The detection of drug-cancer associations not only influences clinical and public health practice, but may also provide insights into mechanisms of carcinogenesis. The clinician contributes to the prevention of drug-induced cancer by being alert to iatrogenic hazards and cooperating in epidemiologic investigations, by weighing risks versus benefits in individual cases, and by discussing with patients the rationale and risks of proposed forms of therapy.


7. DOCID:5774 SCORE: 0.0026792038444375
DOCNO: 366020
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: W D DeWys WD
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of human nutrition.
COUNTRY: ENGLAND
TITLE: Changes in taste sensation and feeding behaviour in cancer patients: a review.
PUBDATE: 19781201
Recent studies suggest the importance of alterations in taste sensation as a determinant of anorexia in cancer patients. These studies collectively support the conclusions that the likelihood of developing abnormalities in taste increases with increasing body burden of tumour, that taste abnormality is reversible on response of the underlying tumour to therapy, and that the abnormalities in taste can be correlated with decreased intake of energy. It is suggested that these studies, and studies currently in progress, may aid our understanding of food choices in cancer patients and may guide the use of food supplements to assist the cancer patient in maintaining adequate energy intake.


8. DOCID:4528 SCORE: 0.00264324624636665
DOCNO: 88120
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: pathology
QUALIFIER: diagnosis
AUTHOR: B V Kliucharev BV
AUTHOR: A V Vorob'ev AV
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Clinico-morphological characteristics of latent form of prostatic cancer]
PUBDATE: 19790501
36 cases of cancer of the prostate, diagnosed at the histological study of the tissue removed during adenomectomy, have been studied. The most common from is a highly differentiated adenocarcinoma with a well developed parenchyma. Elastic consistency and smooth surface of the tumors make difficult their clinical, diagnosis. As compared to other forms of prostatic cancer, these tumors are characterized by a more favourable clinical course and prognosis.


9. DOCID:7129 SCORE: 0.00262086838628402
DOCNO: 684674
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chemical Industry
QUALIFIER: chemically induced
QUALIFIER: chemically induced
QUALIFIER: chemically induced
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: chemically induced
AUTHOR: Y Ohsaki Y
AUTHOR: S Abe S
AUTHOR: K Kimura K
AUTHOR: Y Tsuneta Y
AUTHOR: H Mikami H
AUTHOR: M Murao M
PUBTYPE: Journal Article
JOURNALTITLE: Thorax.
COUNTRY: ENGLAND
TITLE: Lung cancer in Japanese chromate workers.
PUBDATE: 19780601
We have treated ten patients with lung cancer among workers in a chromate factory between 1972 and 1976. Four further cases were also found through death certificates and medical records. Most were smokers and all were men. The average duration of exposure to chromate was 24 years (range 10 to 36). The cell type in our ten patients was squamous in seven and small anaplastic type in three. The primary sites were all in large bronchi. The incidence (person per year) calculated from the number of employees, duration of factory activity, number of cancer patients, and shortest duration of labour period among the patients was 657.9 per 100,000 compared to 13.3 per 100,000 in Japan as a whole.


10. DOCID:6705 SCORE: 0.00246210082096216
DOCNO: 7455110
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: methods
AUTHOR: B J Hillman BJ
AUTHOR: M Silvert M
AUTHOR: G Cook G
AUTHOR: T Stanisic T
AUTHOR: J Bjelland J
AUTHOR: H R Claypool HR
AUTHOR: K Haber K
AUTHOR: H Z Mellins HZ
PUBTYPE: Journal Article
JOURNALTITLE: Radiology.
COUNTRY: UNITED STATES
TITLE: Recognition of bladder tumors by excretory urography.
PUBDATE: 19810201
Bladder tumors initially may be diagnosed by excretory urography in patients undergoing the examination because of specific symptoms or unrelated complaints. Among seven strategies tested by six experienced readers, the combination of early, full-bladder, and postvoiding anteroposterior radiographs was most successful in identifying bladder tumors in a series including 20 cases of biopsy-proved bladder tumor and 19 cases of cystoscopically normal bladders. The postvoiding radiograph, when viewed alone, was the single most valuable projection, and resulted in the correct diagnosis of 14 cancers that were not appreciated on any other single radiograph for a given case. The addition of oblique projections to the other three views did not significantly increase diagnostic sensitivity.


11. DOCID:5318 SCORE: 0.00244198122640801
DOCNO: 7302590
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ethics, Medical
DESCRIPTOR: Government Regulation
DESCRIPTOR: National Institutes of Health (U.S.)
DESCRIPTOR: Research Support
QUALIFIER: therapeutic use
AUTHOR: M Sun M
PUBTYPE: News
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: Cline loses two NIH grants.
PUBDATE: 19811201
To the surprise of some observers, the National Institutes of Health recently issued a second set of sanctions against Martin Cline for violating its regulations governing recombinant DNA research and human experimentation. Cline is the UCLA professor who prematurely conducted the first gene therapy experiments in humans in July 1980. Acting NIH director Thomas Malone accepted the recommendations of the advisory councils of the three institutes funding Cline: the Heart Institute terminated its grant to Cline; the Arthritis Institute decided to continue funding him for nonclinical research; and the Cancer Institute terminated one of Cline's two grants.


12. DOCID:7830 SCORE: 0.0023147672976547
DOCNO: 715632
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: blood
AUTHOR: A Van Den Heever A
AUTHOR: F J Pretorius FJ
AUTHOR: G Falkson G
AUTHOR: I W Simson IW
PUBTYPE: Journal Article
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Hepatitis B surface antigen and primary liver cancer.
PUBDATE: 19780801
Sera of 184 patients were examined to determine the incidence of hepatitis B surface antigen (HBsAg). Ninety-two patients had primary liver cancer (PLC) and there were 92 matched controls. Thirty-one of the 92 patients with PLC and 8 of the 92 patients with no clinical evidence of liver disease had radio-immunoassay-positive tests for HBsAg. The difference was significant (P less than 0,01). In 56 of the patients with PLC it was possible to assess the nature of associated liver disease histologically. HBsAg was found in the sera of 66,6% of patients with postcollapse cirrhosis and in 22,2% of patients with chronic Budd-Chiari syndrome. It is likely that the role played by hepatitis B infection in the pathogenesis of PLC varies according to local circumstances in different geographical areas.


13. DOCID:5737 SCORE: 0.00230706764220429
DOCNO: 707734
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: R H Jesse RH
AUTHOR: A J Ballantyne AJ
AUTHOR: D Larson D
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Radical or modified neck dissection: a therapeutic dilemma.
PUBDATE: 19781001
Three hundred ten evaluable patients received a classic, functional, or spinal accessory-nerve-sparing neck dissection during 1970 to 1975. The functional procedure was at least equal to the classic procedure in the patients in whom it was employed. The spinal accessory-nerve-sparing operation is offered as an alternative to the classic procedure in all patients in whom the nerve is not directly invaded by cancer. If these guidelines are followed, the patient will rarely experience the pain and shoulder dysfunction that result from the loss of the trapezius muscle, while the chances of control of cancer in the neck remain optimal.


14. DOCID:7667 SCORE: 0.00229081251845573
DOCNO: 7398590
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J Nĕmec J
AUTHOR: V Zeman V
AUTHOR: V Nahodil V
AUTHOR: S Vána S
AUTHOR: V Zamrazil V
AUTHOR: V Smejkal V
AUTHOR: H Shameti H
AUTHOR: V Trnka V
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Endokrinologie.
COUNTRY: GERMANY, EAST
TITLE: Metastatic thyroid cancer with severe hyperthyroidism mimicking independent hyperfunctioning thyroid adenoma, showing transition to water-clear-tumour.
PUBDATE: 19800301
A case of different thyroid cancer is reported in detail, showing unusual behaviour both clinically and bioptically. The patient suffered from severe hyperthyroidism, with a scintigraphic finding of independent thyroid adenoma and simultaneous function in pelvic mass proved to be a metastasis of follicular thyroid cancer. Bioptical finding confirmed the aspiration biopsy conclusion that the independently functioning thyroid nodule had been in fact a follicular thyroid cancer. Microscopically, a transition of the usual type of follicular thyroid cancer to solid cancer consisting of water-clear cells was found. Thyroidectomy led to enhancement of uptake in pelvic metastasis but the general condition deteriorated rapidly leading to death by pulmonary embolism. The problem is discussed with regard to the development of hyperthyroidism in thyroid cancer.