0. DOCID:15330 SCORE: 0.00399430880346287
DOCNO: 2654502
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunotherapy
DESCRIPTOR: Lymphokines
QUALIFIER: therapeutic use
QUALIFIER: immunology
QUALIFIER: therapy
AUTHOR: C M van Haelst-Pisani CM
AUTHOR: R J Pisani RJ
AUTHOR: J S Kovach JS
AFFILIATION: Department of Oncology, Mayo Clinic, Rochester, MN 55905.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Mayo Clinic proceedings. Mayo Clinic.
COUNTRY: UNITED STATES
TITLE: Cancer immunotherapy: current status of treatment with interleukin 2 and lymphokine-activated killer cells.
PUBDATE: 19890401
In recent years, the medical community has witnessed a growing interest in the use of adoptive immunotherapy in patients with malignant lesions refractory to standard treatments. Systemic administration of interleukin 2, in combination with the adoptive transfer of a patient's own activated immune cells, has resulted in objective regression of several types of advanced cancers. Pronounced regression of tumor has also been observed with use of systemic interleukin 2 alone. This ability to augment the immune defense system of the host against cancer has stimulated intense clinical and laboratory investigations.


1. DOCID:11832 SCORE: 0.00333017580150736
DOCNO: 6498670
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tobacco Smoke Pollution
QUALIFIER: analysis
AUTHOR: N E Collishaw NE
AUTHOR: J Kirkbride J
AUTHOR: D T Wigle DT
PUBTYPE: Journal Article
JOURNALTITLE: Canadian Medical Association journal.
COUNTRY: CANADA
TITLE: Tobacco smoke in the workplace: an occupational health hazard.
PUBDATE: 19841101
Tobacco smoke, which contains over 50 known carcinogens and many other toxic agents, is a health hazard for nonsmokers who are regularly exposed to it while at work. Involuntary exposure to tobacco smoke annoys and irritates many healthy nonsmokers. Serious acute health effects are probably limited to the one fifth of the population with pre-existing health conditions that are aggravated by exposure to tobacco smoke. The consequences of long-term exposure include decreased lung function and lung cancer. Existing air quality standards for workplaces do not directly specify an acceptable level for tobacco smoke. The evidence on the composition of tobacco smoke and on the health hazards of involuntary exposure suggests that there may not be a "safe" level for such exposure.


2. DOCID:12734 SCORE: 0.00282992903006514
DOCNO: 2727940
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: R Yazigi R
PUBTYPE: Journal Article
JOURNALTITLE: Texas medicine.
COUNTRY: UNITED STATES
TITLE: Early diagnosis of gynecologic cancer.
PUBDATE: 19890401
Malignant gynecologic neoplasms comprise about 15% of cancers in American females. Analysis of cancer treatment results indicates that the most important prognostic factor is stage of disease; thus any strategy to improve survival must include early diagnosis. This can be accomplished by identification of the women at risk, adequate use of screening techniques, updating the primary care physician with clinical and laboratory diagnostic features, and prompt referral to the subspecialist. This approach should drastically reduce the incidence and mortality of invasive gynecologic cancers.


3. DOCID:8644 SCORE: 0.0027966723669138
DOCNO: 6361201
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Automobile Driving
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: R Balarajan R
PUBTYPE: Journal Article
JOURNALTITLE: Journal of epidemiology and community health.
COUNTRY: ENGLAND
TITLE: Malignant lymphomas in road transport workers.
PUBDATE: 19831201
The relative risks of malignant lymphomas among road transport workers were investigated using the National Cancer Registry in England and Wales. Drivers of buses and coaches (OCC unit 120) had increased risks for both Hodgkin's and non-Hodgkin's lymphomas and the drivers of other road passenger vehicles (OCC unit 121) for Hodgkin's lymphomas only. Although the increased risks did not show statistical significance, they corresponded to and reinforced previously described findings based on occupational mortality.


4. DOCID:12862 SCORE: 0.00271578036110848
DOCNO: 3463819
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Information Systems
QUALIFIER: mortality
AUTHOR: B H Patterson BH
AUTHOR: R Bilgrad R
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Use of the National Death Index in cancer studies.
PUBDATE: 19861001
The National Death Index (NDI) is a central file of identifying information on all deaths occurring in the United States since 1979. Potential uses of the NDI as a tool for both short-term and long-term follow-up in cancer treatment, prevention, and occupational studies are suggested. The various steps involved in using the NDI and interpreting the results are described, along with factors influencing the effectiveness of the matching process.


5. DOCID:12868 SCORE: 0.00271577921524267
DOCNO: 3703330
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: blood
QUALIFIER: analysis
AUTHOR: E Leonardo E
AUTHOR: C Dogliotti C
AUTHOR: M Mancuso M
AUTHOR: B Sanfilippo B
AUTHOR: A Oliaro A
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Distribution and prognostic value of CEA and TPA in cancer of the lung]
PUBDATE: 19860301
Serum levels of carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA) were investigated in 53 lung cancer patients. The higher percentage of patients with serum CEA positivity was observed within the anaplastic lung cancer group. TPA serum positivity was found in similar percentage in all the examined groups. Relationship between serum CEA positivity and/or serum TPA positivity and survival were then carried out.


6. DOCID:10063 SCORE: 0.00267059862812483
DOCNO: 6189199
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
AUTHOR: P D van Helden PD
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Interferon--the clinical experience.
PUBDATE: 19830501
Recent trials with interferon, in particular those using pure, recombinant interferon, have provided us with improved data (compared with those obtained in early studies) and show that interferon does hold some promise as a therapeutic agent. When used in the treatment of viral disease, interferon has shown itself to be quite effective in reducing viral titres. While not as effective against cancer, interferon has limited tumour growth, reduced the appearance of metastases and led to a general improvement in patient condition in many cases. This article discusses some of the recent results obtained with interferon in the treatment of viral disease and cancer.


7. DOCID:14880 SCORE: 0.00265740269902413
DOCNO: 2820673
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Thigh
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: M H Torosian MH
AUTHOR: J F Botet JF
AUTHOR: M Paglia M
AFFILIATION: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: Colon carcinoma metastatic to the thigh--an unusual site of metastasis. Report of a case.
PUBDATE: 19871001
Metastasis from colorectal carcinoma occurs by either lymphatic or hematogenous spread. The pattern of metastasis in patients with colorectal malignancy has been characterized by numerous clinical, surgical, and autopsy studies. The most common sites of colorectal metastasis are the liver and lung. Only two previous instances of colorectal carcinoma metastatic to skeletal muscle have been reported. The present report documents the third case of colorectal cancer metastatic to skeletal muscle and reviews the typical pattern of distant metastasis from colorectal carcinoma.


8. DOCID:10949 SCORE: 0.00262150080543097
DOCNO: 6697299
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ear, Middle
QUALIFIER: epidemiology
AUTHOR: R P Morton RP
AUTHOR: P M Stell PM
AUTHOR: P P Derrick PP
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Epidemiology of cancer of the middle ear cleft.
PUBDATE: 19840401
Cancer of the middle ear is an uncommon tumor which has a very poor prognosis. A population-based analysis shows that there are two marked differences between men and women for middle ear cancer in England and Wales: (1) the incidence rate in men continues to rise with advancing age, but in women the rise is proportionately much less after 75 years of age; and (2) the mortality rate in men decreases after 70 to 75 years of age, whereas the mortality for women continues to rise with advancing age. The significance of these differences is not yet clear. No other epidemiologic reports related to middle ear cancer has been found in the literature.


9. DOCID:11897 SCORE: 0.00256955297055701
DOCNO: 6472068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: physiopathology
QUALIFIER: adverse effects
AUTHOR: A M D'iakova AM
AUTHOR: N V Stefani NV
AUTHOR: V G Andreev VG
AUTHOR: V V Pavlov VV
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Kidney function during radiosensitization with metronidazole]
PUBDATE: 19840801
Renal function was studied in patients with laryngeal cancer during radiation therapy performed under the conditions of mean fractionation in the presence of metronidazole radiosensitization up to the summary focal dose of 20 Gy. As compared to the findings before treatment an increase in the level of residual nitrogen, urea, uric acid and a decreased amount of creatinine in the plasma were noted. Decreased clearance of the urea, elevated Ambard's urosecretory constant were observed. The nature of these shifts was preserved even after the termination of subsequent radiation therapy up to the summary focal dose of 32 Gy without using the radiosensitogen. There is a possibility of a direct toxic effect of metronidazole on the renal tissue regardless of the state of oxygenation.


10. DOCID:13472 SCORE: 0.00246566148526394
DOCNO: 3013434
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: G Buzzelli G
AUTHOR: C Smorlesi C
AUTHOR: R Mazzanti R
AUTHOR: A Pampana A
AUTHOR: L Matassi L
AUTHOR: P Simondi P
AUTHOR: P Gentilini P
PUBTYPE: Journal Article
JOURNALTITLE: Chemioterapia : international journal of the Mediterranean Society of Chemotherapy.
COUNTRY: ITALY
TITLE: Chemotherapy of primary and secondary liver cancer: is it useful?
PUBDATE: 19860601
The therapeutic efficacy of three different antiblastic regimens was tested in patients affected by primary or secondary liver cancer. The association of cyclophosphamide and adriamycin gave the best results, despite no partial remission observed with any treatment. As regards the efficacy of antiblastic therapy in this type of tumor, we must conclude that the only detectable effect is a transient improvement of the course of the disease.


11. DOCID:9035 SCORE: 0.00243063831525544
DOCNO: 4067207
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Thyroidectomy
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: adverse effects
AUTHOR: N Panza N
AUTHOR: M De Rosa M
AUTHOR: G Lombardi G
AUTHOR: M Salvatore M
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of endocrinological investigation.
COUNTRY: ITALY
TITLE: Pseudotumor cerebri and thyroid-replacement therapy in patients affected by differentiated thyroid carcinoma.
PUBDATE: 19850801
The pseudotumor cerebri, a neurological syndrome clinically characterized by headaches, vomiting and bilateral papilledema, occurred in two patients, previously subjected to total thyroidectomy for differentiated thyroid carcinoma, after initiation of levothyroxine replacement therapy. In patients with thyroid cancer, subjected to thyroidectomy and then thyroid hormone replacement therapy, the possible development of pseudotumor cerebri syndrome should be considered and differentiated from CNS symptoms due to brain metastases.


12. DOCID:9982 SCORE: 0.00241758800444899
DOCNO: 3863580
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: classification
QUALIFIER: methods
AUTHOR: R J Black RJ
PUBTYPE: Journal Article
JOURNALTITLE: The Australian and New Zealand journal of surgery.
COUNTRY: AUSTRALIA
TITLE: Head and neck cancer staging systems: a comparison between UICC and AJC.
PUBDATE: 19850601
Two major TNM classification systems are currently in use for staging cancer of the head and neck region, i.e. UICC and AJC. This causes confusion when attempting to exchange information and evaluate treatment results between Australia and certain overseas centres. The two systems are described and the effect of any differences on altering survival data is assessed by reviewing 234 cases of squamous carcinoma of the larynx, hypopharynx, oropharynx and oral cavity. The direct correlation between the two systems is established. Shortcomings of the systems are demonstrated and important variables not included in either TNM system are discussed.


13. DOCID:8660 SCORE: 0.00241267177286642
DOCNO: 4063675
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
AUTHOR: G H Whitehouse GH
AUTHOR: S J Leinster SJ
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of radiology.
COUNTRY: ENGLAND
TITLE: The variation of breast parenchymal patterns with age.
PUBDATE: 19850401
The Wolfe classification of mammographic parenchymal patterns has been applied to 9036 women attending a Breast Cancer Screening Unit. Overall, two thirds fell into high risk categories (P2 and DY). The incidence of DY decreases with age, while the low risk categories (N1 and P1) increase with age. P2 remains constant over most of the age range. The implications of these findings are discussed and comparison is made with other series.


14. DOCID:8814 SCORE: 0.00240101185124763
DOCNO: 6350966
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: P Polterauer P
AUTHOR: F Meisl F
AUTHOR: J Funovics J
AUTHOR: J H Holzner JH
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Onkologie.
COUNTRY: SWITZERLAND
TITLE: [Early carcinoma of the stomach. Observations of the course over 23 months. A case report]
PUBDATE: 19830601
A case of an early cancer of the stomach is reported, in which the development of the lesion could be followed by repeated biopsies. Because of a high cardial risk of the patient, the tumor was resected as late as 23 months after the first diagnosis. During this time the lesion changed from a borderline lesion into an early cancer with penetration into the submucosa.