0. DOCID:27831 SCORE: 0.00144731036964979
DOCNO: 10222439
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: A Das A
AUTHOR: F H Hochberg FH
AUTHOR: S McNelis S
AFFILIATION: National University of Singapore, Singapore.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of neuro-oncology.
COUNTRY: NETHERLANDS
TITLE: A review of the therapy of paraneoplastic neurologic syndromes.
PUBDATE: 19990101
The therapy of paraneoplastic neurologic syndromes remains unclear and warrants a systematic review of the literature. Reports in English and foreign language literature were abstracted. Data were sorted by the primary paraneoplastic neurologic syndrome, the primary malignancy, and the methods of treatment. Neurologic improvement follows surgical, chemotherapeutic, and radiation treatments. Adjuvant immunosuppressive therapy with steroids, plasmapheresis, or immunoglobulin may help stabilize the progression of neurologic symptoms. Syndromes characterized by inflammation or neurotransmitter production without neuronal loss are most responsive to therapy. While treatment of the underlying cancer with appropriate surgery, chemotherapy, and radiation is recommended, the paraneoplastic syndrome should probably be managed with immunosuppressive therapy.

1. DOCID:27487 SCORE: 0.00143235639116313
DOCNO: 10088637
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: genetics
AUTHOR: I Garcia-Higuera I
AUTHOR: Y Kuang Y
AUTHOR: A D D'Andrea AD
AFFILIATION: Dana-Farber Cancer Institute, Department of Pediatric Oncology, Boston, MA 02115, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in hematology.
COUNTRY: UNITED STATES
TITLE: The molecular and cellular biology of Fanconi anemia.
PUBDATE: 19990301
Fanconi anemia is a rare autosomal recessive disease characterized by multiple congenital abnormalities, bone marrow failure, and cancer susceptibility. The mean age of onset of anemia is 8 years, and the mean survival is 16 years. Death usually results from complications of bone marrow failure. Considerable progress in Fanconi anemia research has resulted from the recent identification and cloning of three Fanconi anemia genes. The current review describes the structure and function of the Fanconi anemia genes and describes the role of the encoded Fanconi anemia proteins in a cellular pathway controlling chromosome stability.

2. DOCID:26179 SCORE: 0.00115377987648773
DOCNO: 11794059
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymph Node Excision
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: D Chlapík D
AUTHOR: M Gogora M
AFFILIATION: Chirurgické oddelenie NsP, Trencín, Slovenská republika.
PUBTYPE: Journal Article
JOURNALTITLE: Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti.
COUNTRY: Czech Republic
TITLE: [Gastric carcinoma and mediastinal lymph nodes]
PUBDATE: 20011101
The objective of the work was to assess the impact of the shift of gastric cancer in an oral direction in the mediastinal lymph nodes. For this purpose a new miniinvasive lower mediastinoscopy was used in 30 patients. The method is safe and can be used also in other situations. Mediastinal metastases may occur in cancer in the distal and medium third of the stomach. They need not be present when cancer is in the upper third. The shift of gastric carcinoma did not influence the mediastinal nodes.

3. DOCID:26171 SCORE: 0.00115377986828672
DOCNO: 9759681
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: therapy
PUBTYPE: Guideline
PUBTYPE: Journal Article
PUBTYPE: Practice Guideline
PUBTYPE: Review
JOURNALTITLE: Archives of internal medicine.
COUNTRY: UNITED STATES
TITLE: Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults.
PUBDATE: 19980901
An estimated 97 million adults in the United States are overweight or obese, a condition that substantially raises their risk of morbidity from hypertension, dyslipidemia, type 2 diabetes, coronary heart disease, stroke, gallbladder disease, osteoarthritis, sleep apnea and respiratory problems, and endometrial, breast, prostate, and colon cancers. Higher body weights are also associated with increases in all-cause mortality. Obese individuals may also suffer from social stigmatization and discrimination. As a major contributor to preventive death in the United States today, overweight and obesity pose a major public health challenge.

4. DOCID:26752 SCORE: 0.00114572843181957
DOCNO: 11089829
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: D Ratel D
AUTHOR: V Nasser V
AUTHOR: I Dupré I
AUTHOR: A L Benabid AL
AUTHOR: F Berger F
PUBTYPE: Letter
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Antibodies to endostatin in a multifocal glioblastoma patient.
PUBDATE: 20001101
Endostatin, a C-terminal fragment of collagen XVIII is involved in the regulation of neovascularisation in solid tumours in mice. However, few data are available on the concentration of endostatin protein in patients with cancer. Paradoxical results obtained in this way prompted us to investigate an antibody to endostatin. We detected antibodies to endostatin in the serum and in the tumour brain tissue of a patient with a multifocal glioblastoma, and in the serum samples from two patients with aggressive tumours. These data suggest that endostatin overexpression by tumour tissue might induce a humoral immune response.

5. DOCID:26804 SCORE: 0.00114572843175927
DOCNO: 11225443
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: pathology
AUTHOR: A Tannapfel A
AFFILIATION: Institut für Pathologie, Universitätsklinikum Leipzig, Liebigstrasse 26, 04103 Leipzig. tana@medizin.uni-leipzig.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Der Pathologe.
COUNTRY: Germany
TITLE: [Carrent state of molecular pathology of stomach carcinomas]
PUBDATE: 20010101
Gastric carcinoma is one of the commonly diagnosed malignancies and remains an important cause of mortality in the Western hemisphere. Various sequences of genetic alterations may be responsible for the development of gastric cancer, as there exist two histological types: well-differentiated or intestinal-type and poorly differentiated or diffuse-type gastric cancers. While new genetic findings open new perspectives on carcinogenesis and molecular biology of gastric cancer, they have not been widely applied in routine diagnostic procedures, classification systems, disease monitoring, or prognostic assessment. We discuss the mechanisms molecular pathology in relation to their potential clinical relevance.

6. DOCID:27599 SCORE: 0.00114389938634857
DOCNO: 10588031
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Quality of Life
QUALIFIER: therapy
AUTHOR: K E Maher KE
AFFILIATION: Legacy Health System, Portland, OR, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology nursing.
COUNTRY: UNITED STATES
TITLE: Organ preservation.
PUBDATE: 19991101
OBJECTIVES: To review organ preservation in cancer treatment within the context of organ function, treatment-related acute and late toxicities, outcome data, and quality of life. DATA SOURCES: Published review and research articles, proceedings of conferences, and oncology textbooks. CONCLUSIONS: The implementation of surgery, with sequential and/or concurrent chemoradiation, has advanced the success of organ preservation in multiple tumor types and organ systems. Integral to the discussion of organ preservation is consideration of quality of life. IMPLICATIONS FOR NURSING PRACTICE: An understanding of organ preservation in cancer treatment will allow oncology nurses to be more effective patient advocates by providing current information that can be integrated into patient care and education.

7. DOCID:27238 SCORE: 0.00113462687408202
DOCNO: 11489243
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunotherapy
QUALIFIER: therapy
AUTHOR: B I Rini BI
AUTHOR: E J Small EJ
AFFILIATION: University of California at San Francisco Comprehensive Cancer Center, 1600 Divisidero Street, 3rd floor, San Francisco, CA 94115, USA. brini@medicine.ucsf.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current oncology reports.
COUNTRY: United States
TITLE: Immunotherapy for prostate cancer.
PUBDATE: 20010901
The components of an effective immune response have been elucidated in recent years. An understanding of the dysfunction of the immune response in cancer in one or more of these components has led to a variety of immunotherapeutic approaches. These therapeutic strategies are designed to stimulate dendritic cell proliferation, promote antigen uptake and processing, stimulate an effector cell response via direct antigen presentation, or target tumor cells via antibody therapy. Many approaches in prostate cancer have demonstrated successful induction of the desired immune response. Limited clinical success has also been seen.

8. DOCID:25022 SCORE: 0.001112803877893
DOCNO: 11091298
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: P L Manfredi PL
AUTHOR: S Shenoy S
AUTHOR: R Payne R
AFFILIATION: Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Headache.
COUNTRY: UNITED STATES
TITLE: Sumatriptan for headache caused by head and neck cancer.
PUBDATE: 20001001
The use of sumatriptan for the treatment of migraine and cluster headache is well established. Sumatriptan has also been reported to be effective for the treatment of postdural puncture headache, postictal headache, and headache related to intravenous immunoglobulin infusion. We report two patients with headache caused by locally invasive head and neck cancer relieved by oral sumatriptan.

9. DOCID:24417 SCORE: 0.00084426924093762
DOCNO: 16498351
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: G Brandimarte G
AUTHOR: A Tursi A
AFFILIATION: Department of Internal Medicine, Digestive Endoscopy Unit, ''Cristo Re'' Hospital, Rome, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva gastroenterologica e dietologica.
COUNTRY: Italy
TITLE: Self-expanding metal stents as palliative treatment of stenotic relapsed gastric cancer after curative surgery in the elderly.
PUBDATE: 20000301
Palliation of inoperable stenotic gastric and/or duodenal cancer remains an open problem due to high operative mortality and diffuse tumor growth. We describe here in 3 cases of stenotic recurrent gastric cancer in the elderly successful treated using self-expanding metal stents.

10. DOCID:24619 SCORE: 0.000844232982940005
DOCNO: 9827393
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Stomach Neoplasms
AUTHOR: L Perrot L
AUTHOR: G Champault G
AFFILIATION: Service de Chirurgie Générale et Digestive, Hôpital Jean Verdier, Bondy.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal de chirurgie.
COUNTRY: FRANCE
TITLE: [What's new in cancer of the stomach? An overview of the literature of this year]
PUBDATE: 19981001
Literature review for the years 1997 and 1998 presents new concepts for gastric carcinoma (lymphoma and proximal adenocarcinoma excluded). In the light of 50 papers, this update emphasizes the role of Helicobacter Pylori in gastric carcinogenesis, different staging systems, video-laparoscopic staging, treatment of early and advanced gastric cancer and new biological prognostic factors.

11. DOCID:27125 SCORE: 0.000837622488732084
DOCNO: 11513458
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Jurisprudence
QUALIFIER: legislation & jurisprudence
AUTHOR: D E Jose DE
AUTHOR: D Wiedis D
AUTHOR: K Komer K
AFFILIATION: Jose & Wiedis, West Chester, PA 19380-5927, USA. djose@josewiedis.com
PUBTYPE: Journal Article
JOURNALTITLE: Health physics.
COUNTRY: United States
TITLE: A radiation litigation causation analysis which achieves fairness to both litigants.
PUBDATE: 20010901
Very few, if any, radiation induced cancers should appear among nuclear workers in the United States. The existing safety standards and lifetime doses received under the operation of those safety standards are such that less than 1% of the cancers that appear in nuclear workers should be related to their occupational radiation exposure. This small numbers of valid claims is a tribute to the effectiveness of the federal safety standards and to the ALARA professional philosophy of achieving excellence in radiation protection which has marked the field of health physics since its inception.

12. DOCID:27827 SCORE: 0.000836468402411121
DOCNO: 10386124
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: etiology
QUALIFIER: drug therapy
AUTHOR: S R Savage SR
AFFILIATION: Department of Anesthesiology, Dartmouth Medical School, Lebanon, New Hampshire, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Medical clinics of North America.
COUNTRY: UNITED STATES
TITLE: Opioid use in the management of chronic pain.
PUBDATE: 19990501
Opioids are a necessary and effective component of the management of chronic non-cancer-related pain in some patients. Careful structuring, monitoring, and documentation of care are important, but the therapeutic use of opioids is uncomplicated in the majority of patients using opioids and is gratifying for both the patient and the treating physician when it results in significant reduction in pain, improvement in level of function, and a higher quality of life. Opioid therapy is most often successful when combined with other pharmacologic and nonpharmacologic interventions as indicated by the type of pain and the context in which it occurs.

13. DOCID:26001 SCORE: 0.000813312341241457
DOCNO: 9617315
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: M L Rothenberg ML
AFFILIATION: University of Texas, Health Science Center at San Antonio, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [New cancer therapies: balancing risk and benefit]
PUBDATE: 19980501
Irinotecan has been approved in Japan, France and USA, however, its clinical usefulness seems to be differently understood. There is a strong opinion, especially in Japan, that the drug is too toxic since it may harm as many patients than it helps. On the contrary, irinotecan is well accepted to the US cancer chemotherapy practices. With irinotecan as a typical example of new chemotherapeutic agents, benefit and risk of cancer chemotherapy is discussed. Differences in cancer chemotherapy practices between Japan and USA are discussed as well.

14. DOCID:26005 SCORE: 0.000813312333402255
DOCNO: 9855135
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Urinary Diversion
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: Y Yamada Y
AUTHOR: M Fujisawa M
AUTHOR: H Nakagawa H
AUTHOR: H Tanaka H
AUTHOR: A Gotoh A
AUTHOR: K Gohji K
AUTHOR: S Arakawa S
AUTHOR: S Kamidono S
AFFILIATION: Department of Urology, Shinko Hospital, Kobe, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: International journal of urology : official journal of the Japanese Urological Association.
COUNTRY: JAPAN
TITLE: Squamous cell carcinoma in an ileal conduit.
PUBDATE: 19981101
We report a patient with squamous cell carcinoma that developed at the ureteroileal anastomosis and extended into the ileal conduit 11 years after a radical cystectomy for transitional cell carcinoma of the bladder. To our knowledge, this is the first report to document the development of a squamous cell carcinoma in an ileal conduit after a radical procedure for bladder cancer.