0. DOCID:6458 SCORE: 0.00410871956826065
DOCNO: 529220
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: M Gautherie M
PUBTYPE: Journal Article
JOURNALTITLE: Journal de radiologie.
COUNTRY: FRANCE
TITLE: [State of the art and prospects on the use of radiofrequency and microwave hyperthermia in cancer treatment (author's transl)]
PUBDATE: 19791101
The use of microwave hyperthermia for cancer treatment is dealt with, first analyzing the present state of the art, second from a prospective viewpoint. Follow current topics are considered: a) biological data from experiments in vitro and of animals; b) fundamental therapeutic modalities: total body hyperthermia, local hyperthermia; c) technological problems: irradiation frequency, applicators, dosimetry (non-interfering probes, microwave radiometers); d) results of preliminary clinical investigations. Prospects refer to following topics: a) technological: improvement or design of systems for producing and controlling hyperthermia; b) fundamental: models, phantoms and postoperative specimens; dielectric and thermal properties on tissues; part of the vascularization; c) clinical: treatment procedures, long-term therapeutic trials (exclusive or combined hyperthermia, cancerous and healthy tissues).

1. DOCID:6457 SCORE: 0.00296184812188405
DOCNO: 531259
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: urine
QUALIFIER: diagnosis
AUTHOR: Y Oshiumi Y
AUTHOR: H Yagi H
AUTHOR: H Nishitani H
AUTHOR: H Yamawaki H
AUTHOR: C Nakayama C
AUTHOR: I Kamoi I
AUTHOR: K Matsuura K
AUTHOR: S Momose S
PUBTYPE: Journal Article
JOURNALTITLE: Radioisotopes.
COUNTRY: JAPAN
TITLE: [Clinical significance of urinary CEA measurement as a screening test of bladder cancer (author's transl)]
PUBDATE: 19790601
Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V). CEA measurements were positive in 8 of 11 negative cytology cases (class I and II). Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. Therefore we recommend routine use of this combination as a screening system of bladder cancer.

2. DOCID:7915 SCORE: 0.00268748693665449
DOCNO: 464750
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: anatomy & histology
QUALIFIER: anatomy & histology
QUALIFIER: innervation
AUTHOR: G Kudoh G
AUTHOR: K Hoshi K
AUTHOR: T Murakami T
PUBTYPE: Journal Article
JOURNALTITLE: Archivum histologicum Japonicum. Nippon soshikigaku kiroku.
COUNTRY: JAPAN
TITLE: Fluorescence microscopic and enzyme histochemical studies of the innervation of the human spleen.
PUBDATE: 19790401
The innervation of the human spleen was investigated by the fluorescence method for adrenergic nerve fibers (52 cases) and the enzyme histochemical method for cholinergic nerve fibers (27 cases). The spleens examined were removed by laparotomy chiefly for gastric cancer. Adrenergic nerve fibers were demonstrated at the medioadventitial junction and the media in the trabecular arteries, whereas they occurred at the medioadventitial junction in the central and penicillar arteries. They were not found in the trabecular and pulp veins and venules, sheathed capillaries, avascular trabeculae, white and red pulp, and capsule. Nerves containing only a few adrenergic fibers and nerves without adrenergic fibers occurred close to the trabecular arteries. It was also demonstrated that nerves close to the trabecular arteries contain cholinergic fibers. The present study first verifies histochemically that the human spleen is innervated doubly by adrenergic and cholinergic nerve fibers.

3. DOCID:6349 SCORE: 0.00268669288908645
DOCNO: 638951
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: anatomy & histology
QUALIFIER: epidemiology
QUALIFIER: diagnosis
AUTHOR: P M Krook PM
AUTHOR: T Carlile T
AUTHOR: W Bush W
AUTHOR: M H Hall MH
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Mammographic parenchymal patterns as a risk indicator for prevalent and incident cancer.
PUBDATE: 19780301
Different mammographic parenchymal patterns have been found to be associated with significantly different rates for the development of breast cancer in a screening program of self-referred women. These differences are qualitatively similar but of lesser magnitude than those in previous reports by Wolfe which were based on symptomatic women who had had a previous negative mammogram. In addition, this report indicates a small difference in the rate of breast cancer at first mammographic examination, using the same parenchymal classifications. These findings, coupled with other risk factors, may permit the concentration of mammographic screening on a smaller segment of the population at risk, thus improving the benefit to risk ratio.

4. DOCID:7214 SCORE: 0.00263899862032884
DOCNO: 6243882
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
AUTHOR: L Ghosh L
AUTHOR: B C Ghosh BC
AUTHOR: T K Das Gupta TK
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Ultrastructural study of stroma in human mammary carcinoma.
PUBDATE: 19800201
This investigation was designed to study the origin of the stromal component of human mammary carcinoma. Tissues from 30 proved breast carcinomas were studied. Under a light microscope with special stains, an increased connective tissue component was seen in carcinoma. Gluteraldehyde-fixed tissue was examined under an electron microscope. The stroma appeared to be composed of fibroblastic, myofibroblastic, histiocytic and primitive mesenchymal cells. Elastic fibers were intimately intermingled with collagen and reticulin and seen in close association with carcinoma cells. In some areas they were seen inside the carcinoma cells with discontinuous cytoplasmic membrane, as if they were formed by the cancer cells. This observation suggests that breast carcinoma cells play an important role in the production of elastic fibers in association with stromal cells and also stimulate the proliferation of the stromal cellular component.

5. DOCID:7118 SCORE: 0.00245060180192507
DOCNO: 455251
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Follow-Up Studies
QUALIFIER: adverse effects
QUALIFIER: therapy
QUALIFIER: etiology
QUALIFIER: epidemiology
AUTHOR: R Makuch R
AUTHOR: R Simon R
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Recommendations for the analysis of the effect of treatment on the development of second malignancies.
PUBDATE: 19790701
Use of the person-years method for evaluating the association between treatment of a primary cancer and subsequent development of a second malignancy is reviewed. For this type of analysis, the risk of developing a second malignancy is implicitly assumed to remain constant during each patient's follow-up period; this assumption is shown to be inappropriate. When the oncogenic potential of two or more treatments is compared, results are biased unfavorably against the use of intensive treatments that prolong life. Misinterpretation of the oncogenic potential of such treatment regimens can therefore occur, and two alternative statistical techniques are proposed, each for use in a commonly encountered experimental situation. These fairly classic methods of survival analysis are recommended to ascertain the relationship between treatment and development of a second cancer.

6. DOCID:6454 SCORE: 0.00232242990085241
DOCNO: 7353777
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hysterectomy
DESCRIPTOR: Hysterectomy, Vaginal
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: D Kalinkov D
AUTHOR: R Buchholz R
PUBTYPE: Journal Article
JOURNALTITLE: Geburtshilfe und Frauenheilkunde.
COUNTRY: GERMANY, WEST
TITLE: [The treatment of female stress incontinence of urine combined with uterine and vaginal prolapse by vaginal hysterectomy, anterior and posterior colporrhaphy in 1,003 cases (author's transl)]
PUBDATE: 19800101
The type and intensity of pre-operative symptoms and the long term follow-up in 1,003 vaginal hysterectomies with anterior and posterior colporrhaphies are reported. The operative technique corresponds to that of the school of Vienna with emphasis on plication of the urethra with joining of the ischio-carverrosus muscles below the urethra. The pre-operative symptoms disappeared in almost all cases. Constipation and backache improved. Early complications were treated and remained without sequelae. Our method of treatment showed good results and cures the social handicap of stress incontinence. In addition a good prophylaxis against unterine cancer and excellent permanent contraception is provided.

7. DOCID:4389 SCORE: 0.00214091691825635
DOCNO: 347048
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemical synthesis
AUTHOR: B K Sinha BK
AUTHOR: R I Sato RI
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pharmaceutical sciences.
COUNTRY: UNITED STATES
TITLE: Synthesis and biological activities of 10-substituted benzo[b][1,5]naphthyridines.
PUBDATE: 19780301
Eight 10-substituted benzo[b][1,5]naphthyridine derivatives containing N-(pyrrolidino)alkylamines, methanesulfonanilides, and aminoacetanilides were prepared, and their binding with DNA was studied by (a) Tm measurements and (b) the effect on DNA-dependent RNA polymerase in vitro. In addition, they were evaluated as antineoplastic agents in the P-388 test. None of the compounds exhibited anti-cancer activity.

8. DOCID:4752 SCORE: 0.00213537345416482
DOCNO: 7361548
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: A Tanimura A
AUTHOR: K Konaka K
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Acta pathologica japonica.
COUNTRY: JAPAN
TITLE: Carcinoma of the breast in a 5 years old girl.
PUBDATE: 19800101
A case of juvenile carcinoma of mammary gland in a 5 years old girl was reported. Only 32 cases of breast cancer in those under 19 years of age have been reported in Japan. The number of the cases in children under 10 years of age is extremely few totalling only 2 cases, including our case. The prognosis was different between the cases in Japan and those in foreign countries. This may be due to the difference in histology.

9. DOCID:5106 SCORE: 0.00195918014904452
DOCNO: 7011526
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: G R Howe GR
AUTHOR: G J Sherman GJ
AUTHOR: R M Semenciw RM
AUTHOR: A B Miller AB
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Canadian Medical Association journal.
COUNTRY: CANADA
TITLE: Estimated benefits and risks of screening for breast cancer.
PUBDATE: 19810201
A controlled randomized trial of breast cancer screening has been initiated in Canada. This paper presents an analysis of the possible benefit from screening relative to the possible radiation risk from mammography for those women who will be screened in the trial. It shows that with modern low-dose mammography, even when a conservative estimate of possible reduction in mortality due to early detection is applied to the data, the estimated benefit substantially exceeds any possible hazard.

10. DOCID:6219 SCORE: 0.00186472990147558
DOCNO: 657127
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasms, Experimental
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: P Pour P
PUBTYPE: Journal Article
JOURNALTITLE: Cancer letters.
COUNTRY: NETHERLANDS
TITLE: A new and advantageous model for colorectal cancer: its comparison with previous models for a common human disease.
PUBDATE: 19780501
Weekly subcutaneous injection of 10 mg/kg body wt. of N-nitrosobis(2-oxopropyl)amine (BOP), a pancreatic carcinogen in Syrian golden hamsters, induced colorectal cancer in MRC rats in 67% of all males and 33% of all females that survived beyond 43 and 68 weeks, respectively. Tumors were concentrated in specific segments of the large bowel and not found in the small intestine. Although the distribution of cancer in the cecum, and ascending and descending colon was similar in both sexes, rectal cancer predominated significantly in males. These data and the tumor morphology indicate the present model more closely resembles the corresponding human disease than do models in previous relevant experimental studies.

11. DOCID:5087 SCORE: 0.00186048845299979
DOCNO: 445493
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: organization & administration
QUALIFIER: organization & administration
QUALIFIER: therapy
QUALIFIER: organization & administration
AUTHOR: N T Walter NT
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: Continuing care of the cancer patient as a social engineering problem.
PUBDATE: 19790701
Care of the cancer patient has become fractionated toward maintaining the physiological integrity of the patient's life support systems, e.g., the hematopoietic or neurological systems. The concept of total continuing care for the cancer patient is illustrated in this description of a pilot hospice project in a community medical center. The project also illustrates the concept of team support by the health care staff and volunteers. The total continuing care unit described provides support and care which makes living not just possible, but worthwhile, for cancer patients.

12. DOCID:7481 SCORE: 0.00183763286814564
DOCNO: 433295
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: H Biffl H
AUTHOR: H Pristautz H
AUTHOR: F Pinl F
AUTHOR: R Friedl R
AUTHOR: W Leitner W
PUBTYPE: Journal Article
JOURNALTITLE: Wiener medizinische Wochenschrift (1946)
COUNTRY: AUSTRIA
TITLE: [Early diagnosis of cancer of colorectal carcinoma by rectosigmoidoscopy (author's transl)]
PUBDATE: 19790401
The colorectal cancers in greater part grow out of polyps, which can be looked upon as optional precancerosis. Own results together with literature-reports show a distinct increase of the frequency of polyps beyond the age of fortyfive. The only digital palpation of the rectum is insufficient; it leads to the diagnosis of a rectum polyp only in 15.5%, to the diagnosis of a cancer in 13% of cases. With the rectosigmoidoscopy however the diagnosis is successful in 70% of cases. The percentage of precancerous polypous alterations detected by rectosigmoidoscopy is approximately the same in medical check-up as in directed examinations of patients with anorectal discomfort. A restriction of rectosigmoidoscopy to the last-named group of persons is not any longer justified. The polypectomy in the rectum is a real cancer-prevention.

13. DOCID:6540 SCORE: 0.00163236467521321
DOCNO: 7376821
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: physiopathology
AUTHOR: V S Partanen VS
AUTHOR: H Soininen H
AUTHOR: M Saksa M
AUTHOR: P Riekkinen P
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Acta neurologica Scandinavica.
COUNTRY: DENMARK
TITLE: Electromyographic and nerve conduction findings in a patient with neuromyotonia, normocalcemic tetany and small-cell lung cancer.
PUBDATE: 19800401
A 57-year-old man with neuromyotonia and normocalcemic tetany as probable paraneoplastic symptoms of small-cell lung cancer was examined neurophysiologically. In EMG, spontaneous action potential generation was demonstrated in peripheral motor axons. There were also time-locked high-frequency discharges after some voluntarily activated motor unit potentials. After electrical stimulation of motor axons, the M-response as well as spinal F-response or H-reflex was often followed by a sequence of oscillating potentials which could last several hundred msec. There was no evident peripheral polyneuropathy. Tetany subsided when carbamazepine therapy was started. The only striking abnormality in extensive laboratory studies was an increase in the plasma noradrenaline value.

14. DOCID:4343 SCORE: 0.00159106351850104
DOCNO: 537869
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: complications
QUALIFIER: drug therapy
AUTHOR: G Brulé G
AUTHOR: P Belnat P
AUTHOR: A Apchin A
AUTHOR: C Domenge C
AUTHOR: P M Voisin PM
PUBTYPE: Journal Article
JOURNALTITLE: La Nouvelle presse médicale.
COUNTRY: FRANCE
TITLE: [Treatment of chronic pain in advanced malignant disease by oral morphine (author's transl)]
PUBDATE: 19791001
Fifty one patients with terminal cancer suffering severe pains reluctant to other treatment have received morphine by mouth, in a regular regimen. The doses range between 5 and 50 mg every 4 hours. 60% of our patients have their pain alleviated without any side effect impeding the treatment.