0. DOCID:22911 SCORE: 0.00294378937995075
DOCNO: 7488419
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Family Health
DESCRIPTOR: Mothers
QUALIFIER: etiology
AUTHOR: B Gustafsson B
AUTHOR: J Ludvigsson J
AUTHOR: J Carstensen J
AFFILIATION: Department of Paediatrics, Faculty of Health Sciences, University Hospital, Linköping, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer (Oxford, England : 1990)
COUNTRY: ENGLAND
TITLE: Adult cancer risks among the mothers of children with cancer.
PUBDATE: 19950901
We investigated cancer risk among mothers of 2365 children who were diagnosed with cancer between 1973 and 1989 in Sweden. From the date of birth of the child until 31 December 1989, 38 cases of cancer were diagnosed among the mothers. The expected number of cases, according to national rates, was 30.9. Cancer of the thyroid was the only site showing a significantly increased risk among the mothers (observed = 6, expected = 1.2, P < 0.01), but two cases were medullary cancer associated with an inheritable syndrome, and inherited by their children.

1. DOCID:21584 SCORE: 0.00179096134625676
DOCNO: 8206413
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pregnancy Complications, Neoplastic
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: B A Fine BA
AUTHOR: T R Baker TR
AUTHOR: R E Hempling RE
AUTHOR: M Intengan M
AFFILIATION: Department of Gynecologic Oncology, Roswell Park Cancer Institute.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Pregnancy coexisting with serous papillary adenocarcinoma involving both uterus and ovary.
PUBDATE: 19940601
Less than 100 cases have been reported involving coexistent pregnancy and endometrial cancer of epithelial ovarian cancer. Only one case, histologically an endometrioid adenocarcinoma, demonstrated simultaneous involvement of endometrium and ovary. We report an additional case involving both uterus and ovary coexisting with pregnancy but of a serous papillary histology. A viable preterm infant was delivered. The mother is currently without evidence of disease on cisplatin-based chemotherapy.

2. DOCID:22588 SCORE: 0.00179023199324887
DOCNO: 7919922
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosomes, Human, Pair 17
DESCRIPTOR: Oncogenes
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M A Brown MA
AUTHOR: E Solomon E
AFFILIATION: Somatic Cell Genetics Laboratory, Imperial Cancer Research Fund, London, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in genetics & development.
COUNTRY: ENGLAND
TITLE: Towards cloning the familial breast-ovarian cancer gene on chromosome 17.
PUBDATE: 19940601
The past year has seen a great deal of excitement in the field of breast cancer genetics. Since linkage of the familial breast-ovarian cancer gene (BRCA1) to chromosome 17, the critical region has been narrowed to 1.0-1.5 Mb by recombination studies, a detailed physical map has been constructed and much of the region has been cloned in yeast artificial chromosome, bacteriophage P1 and cosmid vectors. The focus now lies on identifying the genes housed within the BRCA1 region and scanning them for oncogenic mutations.

3. DOCID:22628 SCORE: 0.00170269164657202
DOCNO: 8921558
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genetic Predisposition to Disease
DESCRIPTOR: Pharmacogenetics
QUALIFIER: genetics
AUTHOR: E J Calabrese EJ
AFFILIATION: Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst 01003, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Regulatory toxicology and pharmacology : RTP.
COUNTRY: UNITED STATES
TITLE: Biochemical individuality: the next generation.
PUBDATE: 19960801
This paper provides an historical assessment of the development of the concepts of pharmaco- and ecogenetics, including their relationship to major developments in the areas of pharmacology, industrial hygiene, and cancer research in animal models as well as the assessment of inborn metabolic disorders. How this information may be used to evaluate the range of human genetic diversity and its relationship to differential responses to environmental toxins is also considered. The paper concludes by providing a brief summary of several specific conditions in which human genetics traits affect susceptibility to toxic substances.

4. DOCID:21948 SCORE: 0.0014092178651989
DOCNO: 8677161
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: T Izbicki T
AUTHOR: T Laskowska-Klita T
AUTHOR: M Liebhart M
AUTHOR: L Lipińska L
AFFILIATION: Zakład Onkologii Chirurgicznej Instytutu Matki i Dziecka w Warszawie.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Pediatria polska.
COUNTRY: POLAND
TITLE: [Prognostic factors in neuroblastoma in children]
PUBDATE: 19951101
The paper presents the review of prognostic factors which were investigated from the first interests of neuroblastoma, as a model for cancer biology in pediatric oncology. The authors on the basis of other authors experiences and on the own observations, as well stress the importance of basic sciences from the field of molecular biology, cytogenetics and biochemistry, leading to better understanding of the nature of neuroblastoma and to introduction of rational treatment. The stratification of neuroblastoma patients according to the known prognostic variables influenced favourably treatment results.

5. DOCID:23176 SCORE: 0.00140918961611254
DOCNO: 7655520
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: P Graziotti P
AUTHOR: A Losa A
AUTHOR: R Hurle R
AUTHOR: A Lembo A
AFFILIATION: Divisione Urologia, Ospedali Riuniti Bergamo.
PUBTYPE: Journal Article
JOURNALTITLE: Archivio italiano di urologia, andrologia : organo ufficiale [di] Società italiana di ecografia urologica e nefrologica / Associazione ricerche in urologia.
COUNTRY: ITALY
TITLE: [Our current indications for radical prostatectomy]
PUBDATE: 19950601
Radical prostatectomy is the golden standard for localized prostate cancer. The identification of patients with intraprostatic disease who can be cured and will live long enough to benefit from a surgical therapy represents the primary goal of the authors. Target of this article is underlining the importance of an accurate preoperative staging through ultrasound-guided biopsy of seminal vesicles and periprostatic spaces. The positivity of the surgical margin after radical prostatectomy is also taken into account as it represents, according to the authors, an extremely important but often overlooked parameter.

6. DOCID:21321 SCORE: 0.00124805729957532
DOCNO: 8689619
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Fragility
DESCRIPTOR: Chromosomes, Human, Pair 3
QUALIFIER: genetics
QUALIFIER: ultrastructure
AUTHOR: T S Sundareshan TS
AUTHOR: M Augustus M
AFFILIATION: Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Normal expression of fra(3)(p14.2) in lymphocytes of lung cancer patients.
PUBDATE: 19960701
Fragile site (FS) analysis was performed in 10 bronchogenic carcinoma families (non-small cell type) each represented by the patient and one adult offspring. Twenty age- and sex-matched controls were evaluated simultaneously for FS expression. The question whether increased fragility at band 3p14 exists in lung cancer patients or their offspring was examined. The expression level was found to be similar among patients, offspring, and controls.

7. DOCID:20382 SCORE: 0.00111560130734119
DOCNO: 8017816
AUTHOR: W J Smellie WJ
AUTHOR: M Yeatman M
AUTHOR: A G Nash AG
AFFILIATION: Royal Marsden Hospital, Sutton, Surrey.
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the Royal College of Surgeons of England.
COUNTRY: ENGLAND
TITLE: A single axillary crease incision for wide local excision and axillary clearance in breast cancer.
PUBDATE: 19940501
Wide local excision and axillary clearance or sampling has become the standard surgical treatment for many breast cancers. We describe a single incision that allows good access to the primary tumour and the axilla, lies parallel to Kraissl's lines of the skin and gives good cosmetic results.

8. DOCID:21511 SCORE: 0.00111542520218734
DOCNO: 7586138
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Heat
QUALIFIER: metabolism
QUALIFIER: biosynthesis
AUTHOR: M Watanabe M
AUTHOR: K Suzuki K
AUTHOR: S Kodama S
AUTHOR: T Sugahara T
AFFILIATION: Department of Health Sciences, Faculty of Pharmaceutical Sciences, Nagasaki University, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Carcinogenesis.
COUNTRY: ENGLAND
TITLE: Normal human cells at confluence get heat resistance by efficient accumulation of hsp72 in nucleus.
PUBDATE: 19951001
We investigated the heat-sensitivity of normal human cells and cells derived from human cancers (cancer cells) heated at 43 degrees C under different culture conditions. Primary human cells which keep in contact with each other show heat resistance, but cancer cells do not. This does not correlate with the total cellular amount of heat shock protein 72, but rather with accumulation of the protein in the nucleus after heating.

9. DOCID:23742 SCORE: 0.00106928850275711
DOCNO: 8965351
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: H Shibata H
AUTHOR: K Takada K
AUTHOR: T Nakamura T
AFFILIATION: Department of Laboratory Medicine, Nagoya City University Medical School.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Diagnostic cytology for detection of early cancer]
PUBDATE: 19960501
Cytologic methods for detection of early cancers of the uterine cervix, lung and various other organs are discussed. The scraping smear method using a spatula is more effective than the cotton swab or vaginal pool smear method for detection of preinvasive intraepithelial lesions, such as, carcinoma in situ and dysplasias of various degrees of the uterine cervix. The use of sputum specimens pooled for three to five days is recommended for cytologic examination in population screening of lung cancer. Good cytopreparatory techniques, suitable screening and cytodiagnostic classifications of malignancy are also described and emphasized, especially, the importance of properly fixed cytologic material for correct cytopathological diagnosis.

10. DOCID:23473 SCORE: 0.00103078427227007
DOCNO: 8060143
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chemoembolization, Therapeutic
QUALIFIER: secondary
QUALIFIER: therapy
QUALIFIER: secondary
QUALIFIER: therapy
QUALIFIER: pathology
AUTHOR: Y Inoue Y
AUTHOR: H Nakamura H
AUTHOR: M Yano M
AUTHOR: H Akashi H
AUTHOR: S Mizumoto S
AUTHOR: K Yamasaki K
AFFILIATION: Dept. of Radiology, Minoo City Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Hypervascular liver metastases of gastric cancer completely responding to transcatheter oily chemoembolization using epirubicin hydrochloride, mitomycin C and lipiodol]
PUBDATE: 19940801
A 68-year old woman underwent transarterial oily chemoembolization using Lipiodol with epirubicin hydrochloride and mitomycin C for treatment of multiple hypervascular hepatic metastases of gastric cancer. The tumors showed a good fixation of Lipiodol with a complete biologic response. The tumor has been well controlled for eight months by only one chemoembolization on follow-up study. Transcatheter oily chemoembolization may be an effective treatment not only for hepatocellular carcinoma, but also for hypervascular liver metastases from gastrointestinal malignancies.

11. DOCID:22358 SCORE: 0.000947000315649882
DOCNO: 8990859
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Medical Records Systems, Computerized
AUTHOR: G L Gordon GL
PUBTYPE: Journal Article
JOURNALTITLE: Missouri medicine.
COUNTRY: UNITED STATES
TITLE: Computers in the medical practice.
PUBDATE: 19961201
This article is part of a series covering the ever-expanding role of computers in the medical office and practice by Glenn L. Gordon, MD, FACIP. Dr. Gordon is Director, Center for Digestive and Liver Diseases, Clinical Instructor of Medicine at St. Louis University School of Medicine, President of Audrain County Medical Society, Immediate Past President of American Cancer Society-Audrain Unit, and State Council MSIM/ASIM Delegate. This is the first of a series of articles covering the expanding role of computers in our medical practice from office management programs to the Internet. This month's article covers the computerized medical record and what it can do for you.

12. DOCID:20176 SCORE: 0.000942397318990153
DOCNO: 7773028
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: therapy
QUALIFIER: complications
AUTHOR: R Bergeron R
AUTHOR: N Martin N
AUTHOR: A Moreau A
AFFILIATION: Unité de médecine familiale, hôpital Laval.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Canadian family physician Médecin de famille canadien.
COUNTRY: CANADA
TITLE: [Hypercalcemia in cancer patients. Who, when and how to treat?]
PUBDATE: 19950301
The most frequent, potentially fatal, metabolic complication in cancer patients is hypercalcemia. After a discussion of cancer-associated hypercalcemia, we propose an individualized intervention model based on an analysis of the clinical situation, the prognosis, and available treatment options.

13. DOCID:23756 SCORE: 0.000833824174165384
DOCNO: 7672835
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Enzyme Tests
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: diagnosis
AUTHOR: M Walia M
AUTHOR: M Mahajan M
AUTHOR: K Singh K
AFFILIATION: Department of Biochemistry, Government Medical College, Amritsar.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: The Indian journal of medical research.
COUNTRY: INDIA
TITLE: Serum adenosine deaminase, 5'-nucleotidase & alkaline phosphatase in breast cancer patients.
PUBDATE: 19950601
Serum levels of adenosine deaminase (ADA), 5-nucleotidase (5'-NT) and alkaline phosphatase (ALP) were studied in 25 patients of carcinoma breast and 25 normal subjects. Adenosine deaminase was found to be the better probable parameter for the detection of cancer and to assess the development of various stages of cancer whereas 5'-nucleotidase had only diagnostic significance. Serum alkaline phosphatase levels were important for assessing the spread of cancer at secondary sites. After mastectomy a significant decrease was found in the levels of serum ADA and 5'-NT whereas no variations were found in case of serum ALP.

14. DOCID:21828 SCORE: 0.00082203845734246
DOCNO: 7517261
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: therapeutic use
QUALIFIER: complications
QUALIFIER: secondary
AUTHOR: M C Thel MC
AUTHOR: D Ciaccia D
AUTHOR: J J Vredenburgh JJ
AUTHOR: W Peters W
AUTHOR: G R Corey GR
AFFILIATION: Division of Cardiology, Duke University Medical Center, Durham, NC 27710.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Bone marrow transplantation.
COUNTRY: ENGLAND
TITLE: Clostridium septicum abscess in hepatic metastases: successful medical management.
PUBDATE: 19940401
Clostridium septicum bacteremia is frequently associated with hematologic and colonic malignancies and neutropenia. It frequently produces 'metastatic' gangrene with excessive mortality. Standard therapy usually includes surgical debridement and antibiotics. We present a patient with metastatic breast cancer treated with high-dose chemotherapy and bone marrow transplantation. She was treated successfully with antibiotics alone despite developing Cl. septicum bacteremia and gas in hepatic metastases. The pathophysiology of this infection is reviewed.