0. DOCID:10471 SCORE: 0.00140510357297083
DOCNO: 3975656
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: F Cavalli F
PUBTYPE: Journal Article
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: VP-16 in the treatment of malignant lymphomas: a report from the Swiss Group for Clinical Cancer Research (SAKK).
PUBDATE: 19850301
In a pilot study, researchers at The Swiss Group for Clinical Cancer Research (SAKK) treated advanced lymphoma patients with a combination of DDP/VP-16/prednisone. Overall response rate was 34%. Currently, the new platinum derivatives are being studied. Meanwhile, various pilot studies are being conducted in non-Hodgkin's lymphoma (NHL) patients to evaluate the combination, VP-16/bleomycin/procarbazine/ARA-C. Preliminary results are encouraging. It is hoped that this will be an effective salvage regimen for NHL patients and also for use in an alternating regimen along with a well-established first-line treatment.


1. DOCID:11743 SCORE: 0.00140495562047727
DOCNO: 3874273
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neck Dissection
DESCRIPTOR: Surgical Instruments
QUALIFIER: surgery
QUALIFIER: etiology
AUTHOR: R Takagi R
AUTHOR: Y Ohashi Y
AUTHOR: M Abe M
PUBTYPE: Journal Article
JOURNALTITLE: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
COUNTRY: UNITED STATES
TITLE: Blood loss with use of the Shaw scalpel for the treatment of oral cancer.
PUBDATE: 19850801
The Shaw scalpel was used in seven radical operations for oral cancer. The amount of bleeding and postoperative exudate and the occurrence of postoperative complications were compared with that from 12 operations performed with the conventional steel scalpel. The blood loss during the radical neck dissection performed with the Shaw scalpel was 39% of the control value, and no blood transfusions were necessary. There was no increase in the amount of postoperative exudate in the Shaw scalpel group compared with the control group. Skin incision with the Shaw scalpel was accompanied by superficial wound dehiscences in three patients, which healed without any treatment.


2. DOCID:8919 SCORE: 0.00139674840889411
DOCNO: 6623233
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Uterine Cervical Neoplasms
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: M Friedman M
AUTHOR: M Nissenbaum M
AUTHOR: R Lakier R
AUTHOR: S Browde S
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Brain metastases in early cancer of the uterine cervix. A case report.
PUBDATE: 19830901
This paper describes a case of cancer of the uterine cervix (clinical stage IB) in which signs of brain metastases developed within 1 week of diagnosis. Common sites of distant metastases in patients with carcinoma of the cervix are the liver and lung parenchyma. However, these organs were free of disease and only the brain, an extremely rare site, was involved.


3. DOCID:9555 SCORE: 0.0013723725774087
DOCNO: 3918710
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: ABO Blood-Group System
QUALIFIER: blood
AUTHOR: P J Holdsworth PJ
AUTHOR: J Thorogood J
AUTHOR: E A Benson EA
AUTHOR: A D Clayden AD
PUBTYPE: Journal Article
JOURNALTITLE: British medical journal (Clinical research ed.)
COUNTRY: ENGLAND
TITLE: Blood group as a prognostic indicator in breast cancer.
PUBDATE: 19850301
A retrospective analysis of 1001 patients with invasive breast cancer showed a difference in survival between patients with different blood groups. Analysis of time from operation to local recurrence and to general recurrence reinforced this finding. The difference between blood groups became increasingly significant after accepted prognostic factors were allowed for. Patients at particularly high risk of early death or general recurrence were those with blood groups B and AB, those with group AB having a greater relative local recurrence rate.


4. DOCID:9199 SCORE: 0.00111277090967025
DOCNO: 6879932
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: R I Vagner RI
AUTHOR: V A Shutkin VA
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Characteristic clinical manifestations of lung cancer in women]
PUBDATE: 19830501
In women lung cancer was found to have a latent development much more often than in men. An analysis of the duration of the period from the appearance of clinical symptoms of lung cancer up to the medical consultation has shown that duration of the medical history in women was longer than that in men. An earlier admittance to the hospital of men with lung cancer can be explained by an earlier appearance of clinical symptoms making the patient seek medical advice.


5. DOCID:8157 SCORE: 0.00111274251258147
DOCNO: 6208623
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
QUALIFIER: surgery
QUALIFIER: therapeutic use
AUTHOR: D Fleischer D
PUBTYPE: Journal Article
JOURNALTITLE: The Surgical clinics of North America.
COUNTRY: UNITED STATES
TITLE: Endoscopic laser therapy for gastrointestinal neoplasms.
PUBDATE: 19841001
Neoplasms of the esophagus, stomach, duodenum, ampulla, colon, and rectum have been treated with endoscopic laser therapy. For the most part, the therapy has been palliative, although curative treatment has sometimes been achieved. Considerations involved in management of cancers of the GI tract by the laser are discussed and future options envisioned.


6. DOCID:11442 SCORE: 0.00111274239474564
DOCNO: 3981803
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: S Saitoh S
AUTHOR: A Nakanishi A
AUTHOR: T Noda T
AUTHOR: S Yoh S
AUTHOR: Y Ando Y
AUTHOR: I Moriyama I
AUTHOR: M Ichijo M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Tissue polypeptide antigen in gynecological cancer]
PUBDATE: 19850101
Serum tissue polypeptide antigen (TPA), CEA and IAP were measured simultaneously in cervical cancer, corpus cancer and ovarian cancer. TPA levels were increased (more than 110 U/1) in 39% (32/82) of the cervical cancer and in 46% (6/12) of the corpus cancer patients, respectively. In ovarian cancer, TPA levels were elevated (146 U/1 or higher) in 64% (13/22). The positive rate of CEA was somewhat lower than that of TPA and LAP levels were as high as TPA. Moreover, TPA levels were correlated in clinical course. In immunohistochemical examination, TPA was present in cancer cells and absent in normal tissue.


7. DOCID:11990 SCORE: 0.00108444935113555
DOCNO: 7051803
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Outcome and Process Assessment (Health Care)
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: G E Hanks GE
AUTHOR: S Kramer S
AUTHOR: J J Diamond JJ
AUTHOR: D F Herring DF
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Patterns of care outcome survey: national outcome data for six disease sites.
PUBDATE: 19820801
This paper reports the results of the PCS Outcome Surveys for radiation therapy treatment in six disease sites: cervix, Hodgkin's disease, seminoma of the testis, anterior two-thirds of tongue and floor of mouth, larynx and prostate. The survey reflects data obtained for patients treated in 1973. Results for early stages of disease are generally favorable in cancer of the cervix, prostate, testis, larynx and Hodgkin's disease. Control of disease in anterior two-thirds of tongue and floor of mouth was less favorable, but data suggest that more aggressive radiation therapy may contribute to better outcome for this site.


8. DOCID:9409 SCORE: 0.000832261119190251
DOCNO: 6699955
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Urinary Diversion
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: J R Beahrs JR
AUTHOR: T R Fleming TR
AUTHOR: H Zincke H
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Risk of local urethral recurrence after radical cystectomy for bladder cancer.
PUBDATE: 19840201
Radical cystectomy and urinary diversion were performed on 349 patients with transitional cell cancer of the bladder. Followup for 4 to 13 years revealed that 91 and 83 per cent of the patients were free of urethral recurrence 5 and 10 years after cystectomy, respectively. Statistical elimination of urethral recurrences did not improve the over-all survival rate significantly. It appears that supplementation of cystectomy with simultaneous urethrectomy may not be justified if the urethra is not involved by the cancer.


9. DOCID:9381 SCORE: 0.000819968183505695
DOCNO: 7110009
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Registries
QUALIFIER: mortality
AUTHOR: A Bonett A
AUTHOR: D M Roder DM
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Australia.
COUNTRY: AUSTRALIA
TITLE: Survival of South Australian cancer patients: a study of the State's Cancer Registry data.
PUBDATE: 19820601
Survival rates for cancer patients derived from population-based data are a fundamental means of monitoring the effectiveness of treatment for the community at large. We used South Australian Cancer Registry data to study survival by cancer site from date of diagnosis in 1977-79 to August 1980. One-year and two-year cumulative percentage survival rates for all types of invasive cancer were 64% (+/- 0.5%) and 54% (+/- 0.5%) respectively. We anticipate that these findings will provide a yardstick for intra-hospital survival analyses.


10. DOCID:11915 SCORE: 0.000819959779415413
DOCNO: 6654558
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Fluoridation
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: C Chilvers C
PUBTYPE: Journal Article
JOURNALTITLE: International journal of epidemiology.
COUNTRY: ENGLAND
TITLE: Cancer mortality and fluoridation of water supplies in 35 US cities.
PUBDATE: 19831201
The possibility of a cancer risk associated with fluoridation of public water supplies is re-examined using mortality data for 35 US cities, 20 with fluoridated water supplies and 15 with non-fluoridated water. Crude cancer death rates, and mortality ratios standardized for age, sex, and ethnic group are examined, using four alternative sets of standard rates and three different combinations of pericensal years' deaths. Changes in cancer mortality before and after fluoridation in the fluoridated cities are compared with changes in the non-fluoridated cities over the same time period. In none of the analyses have differences in mortality trends been found that could not be due to chance alone. Thus, these results do not support the suggestion of an association between fluoridation of water supplies and cancer mortality.


11. DOCID:11897 SCORE: 0.000819948197886573
DOCNO: 6472068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: physiopathology
QUALIFIER: adverse effects
AUTHOR: A M D'iakova AM
AUTHOR: N V Stefani NV
AUTHOR: V G Andreev VG
AUTHOR: V V Pavlov VV
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Kidney function during radiosensitization with metronidazole]
PUBDATE: 19840801
Renal function was studied in patients with laryngeal cancer during radiation therapy performed under the conditions of mean fractionation in the presence of metronidazole radiosensitization up to the summary focal dose of 20 Gy. As compared to the findings before treatment an increase in the level of residual nitrogen, urea, uric acid and a decreased amount of creatinine in the plasma were noted. Decreased clearance of the urea, elevated Ambard's urosecretory constant were observed. The nature of these shifts was preserved even after the termination of subsequent radiation therapy up to the summary focal dose of 32 Gy without using the radiosensitogen. There is a possibility of a direct toxic effect of metronidazole on the renal tissue regardless of the state of oxygenation.


12. DOCID:9217 SCORE: 0.000819941121089278
DOCNO: 2431737
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tomography, X-Ray Computed
QUALIFIER: adverse effects
QUALIFIER: radiography
AUTHOR: M J Rimmer MJ
AUTHOR: A K Dixon AK
AUTHOR: C D Flower CD
AUTHOR: K Sikora K
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of radiology.
COUNTRY: ENGLAND
TITLE: Bleomycin lung: computed tomographic observations.
PUBDATE: 19851101
Changes characteristic of bleomycin lung were seen in 15 out of 18 patients whose lungs were examined by computed tomography following standard chemotherapy for testicular cancers. These changes affected mainly the posterior aspects of the lungs and were predominantly subpleural in nature. The total dose of bleomycin given did not appear to correlate with the grade of bleomycin damage. Amongst six patients with adequate follow-up studies there has been improvement in the CT appearance of three.


13. DOCID:8018 SCORE: 0.000819940905915892
DOCNO: 6474693
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
AUTHOR: G N Karabanov GN
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Rheologic properties of the blood in lung cancer patients]
PUBDATE: 19840601
Complex examinations performed in 53 patients with lung cancer have revealed pronounced disturbances of rheological properties which manifest themselves as sharp dysproteinemia, increased viscosity of blood, plasma, growing aggregation ability of erythrocytes, their rigidity.


14. DOCID:9945 SCORE: 0.000819929698422116
DOCNO: 6227889
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: methods
QUALIFIER: diagnostic use
AUTHOR: A Pecking A
AUTHOR: G Delorme G
AUTHOR: J Berlie J
AUTHOR: A Goupil A
AUTHOR: M Tubiana M
AUTHOR: F Turpin F
AUTHOR: L Meeus L
AUTHOR: B Clavel B
PUBTYPE: Journal Article
JOURNALTITLE: Presse m├ędicale (Paris, France : 1983)
COUNTRY: FRANCE
TITLE: [Cardiac risks of adriamycin. Early detection of high-risk patients by isotopic cardiac function study]
PUBDATE: 19831101
Adriamycin is known to be effective in the treatment of breast cancer. Serial radionuclide determinations of the left ejection fraction can provide advanced warning of adriamycin cardiotoxicity, prior to clinical signs of the left ventricular dysfunction. Patients at high risk of congestive heart failure can be detected. Depending on the results of the second course of chemotherapy, guidelines and criteria can be laid down to predict the appropriate time for drug discontinuation.