0. DOCID:31031 SCORE: 0.00315426429840296
DOCNO: 16340841
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: J-P Sculier JP
AFFILIATION: Service des Soins Intensifs & Oncologie Thoracique, Institut Jules Bordet, Bruxelles, Belgique.
PUBTYPE: Journal Article
JOURNALTITLE: Revue des maladies respiratoires.
COUNTRY: France
TITLE: [Treatment of thoracic malignancy - results of meta-analyses.]
PUBDATE: 20051201
Meta-analyses dealing with the treatment of thoracic malignancy (non-small cell lung cancer, small cell lung cancer and mesothelioma) were reviewed including isolated ones, based on individual data from clinical trials, or conducted in the context of a systematic review of the literature Their results have changed clinical practice, notably by validating radiochemotherapy for patients with unresectable limited diseases, adjuvant chemotherapy for resectable non-small cell lung cancer and by identifying the most active drugs. However it is important to understand the limits of their methodology in order to avoid inappropriate interpretations.


1. DOCID:31466 SCORE: 0.00315424474461814
DOCNO: 16340841
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Meta-Analysis
QUALIFIER: therapy
AUTHOR: J-P Sculier JP
AFFILIATION: Service des Soins Intensifs & Oncologie Thoracique, Institut Jules Bordet, Bruxelles, Belgique. sculier@bordet.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue des maladies respiratoires.
COUNTRY: France
TITLE: [Treatment of thoracic malignancy--results of meta-analyses]
PUBDATE: 20051201
Meta-analyses dealing with the treatment of thoracic malignancy (non-small cell lung cancer, small cell lung cancer and mesothelioma) were reviewed including isolated ones, based on individual data from clinical trials, or conducted in the context of a systematic review of the literature Their results have changed clinical practice, notably by validating radiochemotherapy for patients with unresectable limited diseases, adjuvant chemotherapy for resectable non-small cell lung cancer and by identifying the most active drugs. However it is important to understand the limits of their methodology in order to avoid inappropriate interpretations.


2. DOCID:31860 SCORE: 0.00315422789816873
DOCNO: 16304042
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Ann A Shi AA
AUTHOR: Dianne Georgian-Smith D
AUTHOR: Felix S Chew FS
AFFILIATION: AVON Breast Comprehensive Center and Department of Radiology, Massachusetts General Hospital, WACC 219R, 15 Parkman St., Boston, MA 02114.
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: United States
TITLE: Imaging of the male breast: self-assessment module.
PUBDATE: 20051201
The educational objectives for this self-assessment module on male breast imaging are for the participant to exercise, self-assess, and improve his or her understanding of the evaluation and management of a breast mass presenting in a man; gain familiarity with the differential diagnosis of breast masses in men and how to evaluate such lesions by imaging; gain familiarity with the sonographic features of breast cancer in men; and gain familiarity with the imaging features of vascular tumors of the breast.


3. DOCID:31481 SCORE: 0.00224453429106614
DOCNO: 16328121
OWNER: NLM
STATUS: In-Process
AUTHOR: R Haberstich R
AUTHOR: J J Tuech JJ
AUTHOR: M Wilt M
AUTHOR: J F Rodier JF
AFFILIATION: Department of Surgical Oncology, Paul Strauss Cancer Institute, Strasbourg, France.
PUBTYPE: Journal Article
JOURNALTITLE: Techniques in coloproctology.
COUNTRY: Italy
TITLE: Anal localization as first manifestation of metastatic ductal breast carcinoma.
PUBDATE: 20051201
The incidence of extrahepatic gastrointestinal metastases from breast cancer is reported in the literature only as necroscopy studies (6-18%); they usually originate from lobular or a mixed ductal-lobular subtype. Nonspecific presenting symptoms, death of the patients caused by other more frequent metastases, and variable radiographic features mimicking primary neoplasms cause a clinical underestimation of this pathology. We report here a case of rectal metastasis from an invasive ductal carcinoma (IDC). This is to our knowledge, the first recorded instance of an anal metastasis from IDC.


4. DOCID:31624 SCORE: 0.00224451393375025
DOCNO: 16304559
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: R Newton R
AUTHOR: T Ribeiro T
AUTHOR: D Casabonne D
AUTHOR: E Alvarez E
AUTHOR: A Touzé A
AUTHOR: T Key T
AUTHOR: P Coursaget P
AFFILIATION: 1Epidemiology & Genetics Unit, Department of Health Sciences, Area 3, Seebohm Rowntree Building, Heslington, York YO10 5DD, UK.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: England
TITLE: Antibody levels against BK virus and prostate, kidney and bladder cancers in the EPIC-Oxford cohort.
PUBDATE: 20051101
In a case-control study nested within the EPIC-Oxford cohort, there were no statistically significant differences in the prevalence or titre of antibodies against BK virus measured in plasma taken prior to diagnosis between cases with cancer of the prostate (n=31), kidney (n=5) or bladder (n=9) and controls (n=45).British Journal of Cancer (2005) 93, 1305-1306. doi:10.1038/sj.bjc.6602869 www.bjcancer.com.


5. DOCID:31835 SCORE: 0.0022444847771058
DOCNO: 16399449
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
AUTHOR: Bernard J Cummings BJ
AFFILIATION: Department of Radiation Oncology, Princess Margaret Hospital/University of Toronto, Toronto, Ontario M5G 2M9, Canada. Bernard.Cummings@rmp.uhn.on.ca
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: United States
TITLE: Current management of anal canal cancer.
PUBDATE: 20051201
Combined-modality therapy consisting of radiation therapy and 5-fluorouracil plus mitomycin remains the standard treatment for localized anal canal cancer, permitting preservation of organ function and achieving high response and survival rates. Current trials are evaluating the ability to deliver higher doses of radiation therapy over shorter intervals. Currently, the most common indication for radical surgery is failure of chemoradiation. Metastatic disease is less responsive to chemoradiation treatment. Neoadjuvant and adjuvant strategies are being evaluated, and additional drugs including capecitabine, irinotecan, and oxaliplatin are being assessed in treatment of localized and advanced disease.


6. DOCID:27289 SCORE: 0.0020148079964972
DOCNO: 10439677
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Heart Valve Prosthesis Implantation
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: C Abad C
AUTHOR: J J Cáceres JJ
AUTHOR: E Redondo E
AFFILIATION: Servicio de Cirugía Cardiovascular, Hospital Universitario Nuestra Señora del Pino, Las Palmas de Gran Canaria.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Revista española de cardiología.
COUNTRY: SPAIN
TITLE: [Fortuitous diagnosis of an undifferentiated large cell carcinoma during cardiac surgery]
PUBDATE: 19990701
A 57 years old man was operated for aortic valve replacement. During the operation a mediastinal lymph node was biopsed with the result of undifferenciated large cell carcinoma with neuroendocrine features. Three months after surgery the patient died of non-cardiac related reasons, postmorten examination was not performed. Although the primary tumor could not be assessed, probably the lung was the original location. The histological classification of lung cancer is exposed, with special reference in the undifferenciated large cell type with neuroendocrine features.


7. DOCID:26279 SCORE: 0.00193400373139681
DOCNO: 11680028
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
DESCRIPTOR: Rural Health
DESCRIPTOR: Vaginal Smears
DESCRIPTOR: Women's Health
QUALIFIER: methods
AUTHOR: L Jaros L
AUTHOR: E D Eaker ED
AUTHOR: P L Remington PL
AFFILIATION: Security Health Plan, Marshfield, Wisconsin, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of public health management and practice : JPHMP.
COUNTRY: United States
TITLE: Women's Health Alliance Intervention Study: description of a breast and cervical cancer screening program.
PUBDATE: 20010901
The Women's Health Alliance Intervention Study is a community-based intervention study designed to determine if county-based coalitions can increase breast and cervical cancer screening rates among women aged 40 and older in four rural Wisconsin counties. This article describes the intervention process and demonstrates the feasibility of rural volunteer coalitions to promote breast and cervical cancer screening in communities. An accompanying article in this issue describes the effectiveness of these interventions.


8. DOCID:25131 SCORE: 0.0019240105648457
DOCNO: 10879049
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: H Oda H
AFFILIATION: Department of Pathology, Graduate School of Medicine, University of Tokyo.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [p53 transgenic and knockout mice]
PUBDATE: 20000601
Li-Fraumeni syndrome(LFS) and its relation to the p53 gene and p53 gene transgenic and targeting mice are reviewed. LFS is a hereditary cancer-prone syndrome mainly with germ line mutation of p53 gene. p53 deficient mice, especially heterozygous mice, may serve as a model for human LFS, although there are several discrepancies between them. Carcinogenesis experiment using p53 deficient mice may be important to clarify the role of p53 in tumorigenesis in vivo.


9. DOCID:24350 SCORE: 0.00162482712363547
DOCNO: 11195420
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: legislation & jurisprudence
AUTHOR: H Holmes H
AFFILIATION: University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA. hholmes@mdanderson.org
PUBTYPE: Journal Article
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: United States
TITLE: Oncology legislative update.
PUBDATE: 20001101
This article reviews current legislative and regulatory issues of importance to the oncology community. Topics include patient protection, Medicare support of clinical trials, research data protection, the Medical Innovation Tax Credit, National Cancer Institute appropriations, and medical record privacy issues. Other topics discussed included funding for stem-cell research, genetic therapy oversight, and coverage for uninsured patients.


10. DOCID:29364 SCORE: 0.00158648122282273
DOCNO: 15145243
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: therapy
AUTHOR: Jin-Woo Park JW
AUTHOR: Orlo H Clark OH
AFFILIATION: Department of Surgery, College of Medicine, Chungbuk National University, San 62 Kaeshin-dong, Heungdok-gu, Cheongju, 361-763 South Korea.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Surgical clinics of North America.
COUNTRY: United States
TITLE: Redifferentiation therapy for thyroid cancer.
PUBDATE: 20040601
Thyroid tumorigenesis and carcinogenesis accompany progressive loss of thyroid-specific differentiated functions. Some thyroid cancers are or become dedifferentiated, and they become refractory to efficacy-proven conventional therapies such as radioiodine ablation therapy and thyrotropin (TSH)-suppressive therapy. Redifferentiation therapy by either redifferentiating agents or gene transfer of differentiation-related genes may retard tumor growth and make tumors respond to conventional therapies.


11. DOCID:31738 SCORE: 0.00154954179673784
DOCNO: 16213720
OWNER: NLM
STATUS: In-Process
AUTHOR: Pui-Kai Li PK
AUTHOR: Zili Xiao Z
AUTHOR: Zhigen Hu Z
AUTHOR: Bulbul Pandit B
AUTHOR: Yanjun Sun Y
AUTHOR: Dan L Sackett DL
AUTHOR: Karl Werbovetz K
AUTHOR: Andrew Lewis A
AUTHOR: Jayasekar Johnsamuel J
AFFILIATION: Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. li.27@osu.edu
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry letters.
COUNTRY: England
TITLE: Conformationally restricted analogs of Combretastatin A-4 derived from SU5416.
PUBDATE: 20051201
A series of compounds originally derived from the vascular endothelial growth factor receptor tyrosine kinase inhibitor, SU5416, was synthesized and evaluated. The most potent compound in this series, compound 7, structurally resembles the potent anti-microtubule agent Combretastatin A-4, inhibited tubulin polymerization, and showed potent growth inhibitory activities on both prostate and breast cancer lines with IC(50) values in low to subnanomolar range.


12. DOCID:25768 SCORE: 0.00140154593667612
DOCNO: 10188414
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: pathology
QUALIFIER: methods
AUTHOR: N L Welykholowa NL
AFFILIATION: Brandon General Hospital, Manitoba, Canada.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Canadian operating room nursing journal.
COUNTRY: CANADA
TITLE: Lymphatic mapping and sentinel node biopsy. New technology for women's health.
PUBDATE: 19981001
The current surgical standard of care for the management of invasive breast cancer is the complete removal of the cancer with documented negative margins by either mastectomy or lumpectomy followed by complete axillary lymph node dissection. These procedures can be associated with significant morbidity which leads to increased hospitalizations, increased overall costs and considerable discomfort and life-style changes for the patients. With sentinel node identification and biopsy, patients with probable negative lymph nodes may avoid axillary dissection, and easily be treated as outpatients.


13. DOCID:25782 SCORE: 0.00140154588650692
DOCNO: 12567957
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Phytotherapy
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: drug therapy
QUALIFIER: pharmacology
QUALIFIER: drug therapy
AUTHOR: Q Li Q
AUTHOR: S Li S
AUTHOR: G Yang G
AFFILIATION: Jinan University, Guangzhou 510632.
PUBTYPE: Journal Article
JOURNALTITLE: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
COUNTRY: China
TITLE: [Study of anti-tumor action and influence on immune function of Allium stativum]
PUBDATE: 19980501
Applying mice test on cancer model of S180 and Lewis cancer by using method clystered stomach(oral), observs the Anti-tumor function. Experiments showed that Allium sativum can inhibit tumor growth and Lengthen lift duration of mice, the rate of inhibiting tumor was 74.35% and life lengthening rate were 42.4%, with control grou comparison. There was profund difference between them. Besides, we discoved Allium sativum can raise immune function of mice.


14. DOCID:31006 SCORE: 0.00139977040759641
DOCNO: 11895754
AUTHOR: Niall O'Higgins N
AUTHOR: Bin B R Kroon BB
AFFILIATION: St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
PUBTYPE: Comment
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin du cancer.
COUNTRY: France
TITLE: Observations on surgical oncology and the Livre blanc.
PUBDATE: 20020201
A high standard of surgical care is the most crucial factor in determining outcome for the great majority of patients with solid malignant tumours. Although acknowledged by most experts this fact is insufficiently recognised by the medical community, by health administrators, by the lay public or by political decision-makers. Difficulty in appreciating the importance of quality in surgery may have come about because of the changing role of the surgeon in cancer care. While remaining the most important instrument in curative cancer treatment, surgery has been joined by other modalities active against malignant disease.