0. DOCID:31031 SCORE: 0.00315426429840296
DOCNO: 16340841
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: J-P Sculier JP
AFFILIATION: Service des Soins Intensifs & Oncologie Thoracique, Institut Jules Bordet, Bruxelles, Belgique.
PUBTYPE: Journal Article
JOURNALTITLE: Revue des maladies respiratoires.
COUNTRY: France
TITLE: [Treatment of thoracic malignancy - results of meta-analyses.]
PUBDATE: 20051201
Meta-analyses dealing with the treatment of thoracic malignancy (non-small cell lung cancer, small cell lung cancer and mesothelioma) were reviewed including isolated ones, based on individual data from clinical trials, or conducted in the context of a systematic review of the literature Their results have changed clinical practice, notably by validating radiochemotherapy for patients with unresectable limited diseases, adjuvant chemotherapy for resectable non-small cell lung cancer and by identifying the most active drugs. However it is important to understand the limits of their methodology in order to avoid inappropriate interpretations.


1. DOCID:31466 SCORE: 0.00315424474461814
DOCNO: 16340841
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Meta-Analysis
QUALIFIER: therapy
AUTHOR: J-P Sculier JP
AFFILIATION: Service des Soins Intensifs & Oncologie Thoracique, Institut Jules Bordet, Bruxelles, Belgique. sculier@bordet.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue des maladies respiratoires.
COUNTRY: France
TITLE: [Treatment of thoracic malignancy--results of meta-analyses]
PUBDATE: 20051201
Meta-analyses dealing with the treatment of thoracic malignancy (non-small cell lung cancer, small cell lung cancer and mesothelioma) were reviewed including isolated ones, based on individual data from clinical trials, or conducted in the context of a systematic review of the literature Their results have changed clinical practice, notably by validating radiochemotherapy for patients with unresectable limited diseases, adjuvant chemotherapy for resectable non-small cell lung cancer and by identifying the most active drugs. However it is important to understand the limits of their methodology in order to avoid inappropriate interpretations.


2. DOCID:31860 SCORE: 0.00315422789816873
DOCNO: 16304042
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Ann A Shi AA
AUTHOR: Dianne Georgian-Smith D
AUTHOR: Felix S Chew FS
AFFILIATION: AVON Breast Comprehensive Center and Department of Radiology, Massachusetts General Hospital, WACC 219R, 15 Parkman St., Boston, MA 02114.
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: United States
TITLE: Imaging of the male breast: self-assessment module.
PUBDATE: 20051201
The educational objectives for this self-assessment module on male breast imaging are for the participant to exercise, self-assess, and improve his or her understanding of the evaluation and management of a breast mass presenting in a man; gain familiarity with the differential diagnosis of breast masses in men and how to evaluate such lesions by imaging; gain familiarity with the sonographic features of breast cancer in men; and gain familiarity with the imaging features of vascular tumors of the breast.


3. DOCID:22911 SCORE: 0.00294378937995075
DOCNO: 7488419
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Family Health
DESCRIPTOR: Mothers
QUALIFIER: etiology
AUTHOR: B Gustafsson B
AUTHOR: J Ludvigsson J
AUTHOR: J Carstensen J
AFFILIATION: Department of Paediatrics, Faculty of Health Sciences, University Hospital, Linköping, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer (Oxford, England : 1990)
COUNTRY: ENGLAND
TITLE: Adult cancer risks among the mothers of children with cancer.
PUBDATE: 19950901
We investigated cancer risk among mothers of 2365 children who were diagnosed with cancer between 1973 and 1989 in Sweden. From the date of birth of the child until 31 December 1989, 38 cases of cancer were diagnosed among the mothers. The expected number of cases, according to national rates, was 30.9. Cancer of the thyroid was the only site showing a significantly increased risk among the mothers (observed = 6, expected = 1.2, P < 0.01), but two cases were medullary cancer associated with an inheritable syndrome, and inherited by their children.


4. DOCID:31481 SCORE: 0.00224453429106614
DOCNO: 16328121
OWNER: NLM
STATUS: In-Process
AUTHOR: R Haberstich R
AUTHOR: J J Tuech JJ
AUTHOR: M Wilt M
AUTHOR: J F Rodier JF
AFFILIATION: Department of Surgical Oncology, Paul Strauss Cancer Institute, Strasbourg, France.
PUBTYPE: Journal Article
JOURNALTITLE: Techniques in coloproctology.
COUNTRY: Italy
TITLE: Anal localization as first manifestation of metastatic ductal breast carcinoma.
PUBDATE: 20051201
The incidence of extrahepatic gastrointestinal metastases from breast cancer is reported in the literature only as necroscopy studies (6-18%); they usually originate from lobular or a mixed ductal-lobular subtype. Nonspecific presenting symptoms, death of the patients caused by other more frequent metastases, and variable radiographic features mimicking primary neoplasms cause a clinical underestimation of this pathology. We report here a case of rectal metastasis from an invasive ductal carcinoma (IDC). This is to our knowledge, the first recorded instance of an anal metastasis from IDC.


5. DOCID:31624 SCORE: 0.00224451393375025
DOCNO: 16304559
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: R Newton R
AUTHOR: T Ribeiro T
AUTHOR: D Casabonne D
AUTHOR: E Alvarez E
AUTHOR: A Touzé A
AUTHOR: T Key T
AUTHOR: P Coursaget P
AFFILIATION: 1Epidemiology & Genetics Unit, Department of Health Sciences, Area 3, Seebohm Rowntree Building, Heslington, York YO10 5DD, UK.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: England
TITLE: Antibody levels against BK virus and prostate, kidney and bladder cancers in the EPIC-Oxford cohort.
PUBDATE: 20051101
In a case-control study nested within the EPIC-Oxford cohort, there were no statistically significant differences in the prevalence or titre of antibodies against BK virus measured in plasma taken prior to diagnosis between cases with cancer of the prostate (n=31), kidney (n=5) or bladder (n=9) and controls (n=45).British Journal of Cancer (2005) 93, 1305-1306. doi:10.1038/sj.bjc.6602869 www.bjcancer.com.


6. DOCID:31835 SCORE: 0.0022444847771058
DOCNO: 16399449
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
AUTHOR: Bernard J Cummings BJ
AFFILIATION: Department of Radiation Oncology, Princess Margaret Hospital/University of Toronto, Toronto, Ontario M5G 2M9, Canada. Bernard.Cummings@rmp.uhn.on.ca
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: United States
TITLE: Current management of anal canal cancer.
PUBDATE: 20051201
Combined-modality therapy consisting of radiation therapy and 5-fluorouracil plus mitomycin remains the standard treatment for localized anal canal cancer, permitting preservation of organ function and achieving high response and survival rates. Current trials are evaluating the ability to deliver higher doses of radiation therapy over shorter intervals. Currently, the most common indication for radical surgery is failure of chemoradiation. Metastatic disease is less responsive to chemoradiation treatment. Neoadjuvant and adjuvant strategies are being evaluated, and additional drugs including capecitabine, irinotecan, and oxaliplatin are being assessed in treatment of localized and advanced disease.


7. DOCID:27289 SCORE: 0.0020148079964972
DOCNO: 10439677
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Heart Valve Prosthesis Implantation
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: C Abad C
AUTHOR: J J Cáceres JJ
AUTHOR: E Redondo E
AFFILIATION: Servicio de Cirugía Cardiovascular, Hospital Universitario Nuestra Señora del Pino, Las Palmas de Gran Canaria.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Revista española de cardiología.
COUNTRY: SPAIN
TITLE: [Fortuitous diagnosis of an undifferentiated large cell carcinoma during cardiac surgery]
PUBDATE: 19990701
A 57 years old man was operated for aortic valve replacement. During the operation a mediastinal lymph node was biopsed with the result of undifferenciated large cell carcinoma with neuroendocrine features. Three months after surgery the patient died of non-cardiac related reasons, postmorten examination was not performed. Although the primary tumor could not be assessed, probably the lung was the original location. The histological classification of lung cancer is exposed, with special reference in the undifferenciated large cell type with neuroendocrine features.


8. DOCID:26279 SCORE: 0.00193400373139681
DOCNO: 11680028
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
DESCRIPTOR: Rural Health
DESCRIPTOR: Vaginal Smears
DESCRIPTOR: Women's Health
QUALIFIER: methods
AUTHOR: L Jaros L
AUTHOR: E D Eaker ED
AUTHOR: P L Remington PL
AFFILIATION: Security Health Plan, Marshfield, Wisconsin, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of public health management and practice : JPHMP.
COUNTRY: United States
TITLE: Women's Health Alliance Intervention Study: description of a breast and cervical cancer screening program.
PUBDATE: 20010901
The Women's Health Alliance Intervention Study is a community-based intervention study designed to determine if county-based coalitions can increase breast and cervical cancer screening rates among women aged 40 and older in four rural Wisconsin counties. This article describes the intervention process and demonstrates the feasibility of rural volunteer coalitions to promote breast and cervical cancer screening in communities. An accompanying article in this issue describes the effectiveness of these interventions.


9. DOCID:25131 SCORE: 0.0019240105648457
DOCNO: 10879049
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: H Oda H
AFFILIATION: Department of Pathology, Graduate School of Medicine, University of Tokyo.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [p53 transgenic and knockout mice]
PUBDATE: 20000601
Li-Fraumeni syndrome(LFS) and its relation to the p53 gene and p53 gene transgenic and targeting mice are reviewed. LFS is a hereditary cancer-prone syndrome mainly with germ line mutation of p53 gene. p53 deficient mice, especially heterozygous mice, may serve as a model for human LFS, although there are several discrepancies between them. Carcinogenesis experiment using p53 deficient mice may be important to clarify the role of p53 in tumorigenesis in vivo.


10. DOCID:18908 SCORE: 0.00181878777844546
DOCNO: 2142831
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: statistics & numerical data
QUALIFIER: etiology
QUALIFIER: therapy
AUTHOR: R R Seals RR
AUTHOR: D J Seals DJ
PUBTYPE: Journal Article
JOURNALTITLE: Texas dental journal.
COUNTRY: UNITED STATES
TITLE: Dental care for cancer patients: a survey of Texas dental school graduates.
PUBDATE: 19900601
A survey of recent Texas dental school graduates regarding their preparedness for addressing the oral health care needs of cancer patients in their practices suggests several trends. Many graduates (26%) do not feel adequately prepared to manage and provide oral care for cancer patients. Over 95% of the dentists surveyed expressed interest in locally sponsored continuing education courses on the oral health care of cancer patients. Clearly, both predoctoral and postdoctoral dental education must recognize the need for formalized instruction on the oral cre of cancer patients if general dentists are to provide high-quality, comprehensive dental care for these patients.


11. DOCID:21584 SCORE: 0.00179096134625676
DOCNO: 8206413
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pregnancy Complications, Neoplastic
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: B A Fine BA
AUTHOR: T R Baker TR
AUTHOR: R E Hempling RE
AUTHOR: M Intengan M
AFFILIATION: Department of Gynecologic Oncology, Roswell Park Cancer Institute.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Pregnancy coexisting with serous papillary adenocarcinoma involving both uterus and ovary.
PUBDATE: 19940601
Less than 100 cases have been reported involving coexistent pregnancy and endometrial cancer of epithelial ovarian cancer. Only one case, histologically an endometrioid adenocarcinoma, demonstrated simultaneous involvement of endometrium and ovary. We report an additional case involving both uterus and ovary coexisting with pregnancy but of a serous papillary histology. A viable preterm infant was delivered. The mother is currently without evidence of disease on cisplatin-based chemotherapy.


12. DOCID:22588 SCORE: 0.00179023199324887
DOCNO: 7919922
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosomes, Human, Pair 17
DESCRIPTOR: Oncogenes
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M A Brown MA
AUTHOR: E Solomon E
AFFILIATION: Somatic Cell Genetics Laboratory, Imperial Cancer Research Fund, London, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in genetics & development.
COUNTRY: ENGLAND
TITLE: Towards cloning the familial breast-ovarian cancer gene on chromosome 17.
PUBDATE: 19940601
The past year has seen a great deal of excitement in the field of breast cancer genetics. Since linkage of the familial breast-ovarian cancer gene (BRCA1) to chromosome 17, the critical region has been narrowed to 1.0-1.5 Mb by recombination studies, a detailed physical map has been constructed and much of the region has been cloned in yeast artificial chromosome, bacteriophage P1 and cosmid vectors. The focus now lies on identifying the genes housed within the BRCA1 region and scanning them for oncogenic mutations.


13. DOCID:22628 SCORE: 0.00170269164657202
DOCNO: 8921558
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genetic Predisposition to Disease
DESCRIPTOR: Pharmacogenetics
QUALIFIER: genetics
AUTHOR: E J Calabrese EJ
AFFILIATION: Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst 01003, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Regulatory toxicology and pharmacology : RTP.
COUNTRY: UNITED STATES
TITLE: Biochemical individuality: the next generation.
PUBDATE: 19960801
This paper provides an historical assessment of the development of the concepts of pharmaco- and ecogenetics, including their relationship to major developments in the areas of pharmacology, industrial hygiene, and cancer research in animal models as well as the assessment of inborn metabolic disorders. How this information may be used to evaluate the range of human genetic diversity and its relationship to differential responses to environmental toxins is also considered. The paper concludes by providing a brief summary of several specific conditions in which human genetics traits affect susceptibility to toxic substances.


14. DOCID:18345 SCORE: 0.0016620666383385
DOCNO: 1931775
AUTHOR: I Chin-Yee I
AUTHOR: A T Porter AT
AUTHOR: R C Lohmann RC
AFFILIATION: Department of Hematology/Blood Bank, Victoria Hospital Corporation, London, Ontario, Canada.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical oncology (Royal College of Radiologists (Great Britain))
COUNTRY: ENGLAND
TITLE: Acute non-lymphocytic leukaemia and myelofibrosis following sequential hemibody irradiation for prostatic carcinoma.
PUBDATE: 19910901
Sequential hemibody radiotherapy (SHBI) is currently being evaluated in clinical trials as adjuvant treatment in cancer patients who are potential long-term survivors. The potential late adverse effects of this therapeutic modality on the bone marrow may place patients at risk for the complications of aplasia, leukaemia, and myeloproliferative syndromes. We describe a case of acute non-lymphocytic leukaemia and myelofibrosis following SHBI for prostate carcinoma. The possible role of radiation in the induction of these abnormalities is discussed.