0. DOCID:15491 SCORE: 0.00343411403204513
DOCNO: 2662789
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: pathology
AUTHOR: N S Hadjis NS
AUTHOR: A Adam A
AUTHOR: I Blenkharn I
AUTHOR: G Hatzis G
AUTHOR: I S Benjamin IS
AUTHOR: L H Blumgart LH
AFFILIATION: Hepatobiliary Surgical Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London, England.
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Primary sclerosing cholangitis associated with liver atrophy.
PUBDATE: 19890701
Of 27 patients with primary sclerosing cholangitis, 4 were found on investigation and subsequently at operation to have gross lobar atrophy. The disease was particularly severe in the hilar region. Three of the four patients were asymptomatic prior to the onset of jaundice. The presence of atrophy precipitated laparotomy to exclude cancer in two cases. Marked disparity in size between liver lobes precluded a hilar approach to relieve extrahepatic obstruction in two patients. Prolonged follow-up excluded coincident malignant disease. Selective liver atrophy should be considered part of the disease spectrum in primary sclerosing cholangitis.

1. DOCID:15843 SCORE: 0.00312607775154932
DOCNO: 3752729
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: V W Vanek VW
AUTHOR: C L Whitt CL
AUTHOR: R A Abdu RA
AUTHOR: W R Kennedy WR
PUBTYPE: Journal Article
JOURNALTITLE: The American surgeon.
COUNTRY: UNITED STATES
TITLE: Comparison of right colon, left colon, and rectal carcinoma.
PUBDATE: 19860901
Three hundred fifteen cases of adenocarcinoma were analyzed for differences between lesions in the right colon, left colon, and rectum for the period 1978 to 1983. The right colon cancers accounted for 1/3 of the cases and were associated with a higher incidence of anemia. The incidence of obstruction was the same between the right and left colon but lower for the rectal lesions. Left colon and rectal cancers had a higher incidence of gross bleeding than right colon cancers, but all had a high rate of occult blood in the stool. The Duke stage of the lesions, which was similar throughout the colon and rectum, is a reliable prognostic indicator.

2. DOCID:15007 SCORE: 0.00296606342277797
DOCNO: 3048333
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Transfection
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M P Moyer MP
AUTHOR: J W Egan JW
AUTHOR: J B Aust JB
AUTHOR: R C Moyer RC
AFFILIATION: Department of Surgery, University of Texas Health Science Center, San Antonio 78284.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Biochemistry and cell biology = Biochimie et biologie cellulaire.
COUNTRY: CANADA
TITLE: DNA-mediated transfection as a model for oncogenesis.
PUBDATE: 19880601
DNA transfer technology has greatly contributed to progress in understanding molecular biology and genetics. In recent years, great efforts have been expended to determine the oncogenic potential of single, defined genes or complex gene mixtures as a prelude to defining the role those genes may play in neoplastic transformation in vitro and tumor induction in vivo. This paper reviews the currently available DNA transfection techniques and their application toward understanding cancer initiation and progression, and how the in vitro and animal models may apply to human cancer.

3. DOCID:15976 SCORE: 0.00236561249180047
DOCNO: 3586344
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: Y Iitsuka Y
AUTHOR: T Matsui T
AUTHOR: Y Hirooka Y
AUTHOR: Y Kobayashi Y
AUTHOR: H Kishimoto H
AUTHOR: H Hiraoka H
AUTHOR: A Kimura A
AUTHOR: S Koga S
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Prognosis of gastric cancer patients with special reference to the area of serosal cancerous invasion]
PUBDATE: 19870301
The area of serosal cancerous invasion and intraperitoneal free cancer cells were examined in 360 gastric cancer cases. The positivity rate of intraperitoneal free cancer cells was 20% in the group with under 20 cm2 of serosal invasion, 59% with 20 cm2 to 30 cm2, and 76% over 30 cm. The postoperative survival rate was significantly lower in the group with free cancer cells than in the group without them. Prognosis was better in case with the area of serosal invasion was smaller. Hematogenous metastasis was frequent under 20 cm2, but over 20 cm2, peritoneal metastasis predominated.

4. DOCID:15302 SCORE: 0.00217425481719197
DOCNO: 3789911
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: C Moore C
AUTHOR: J G Kuhns JG
AUTHOR: R A Greenberg RA
PUBTYPE: Journal Article
JOURNALTITLE: Archives of surgery (Chicago, Ill. : 1960)
COUNTRY: UNITED STATES
TITLE: Thickness as prognostic aid in upper aerodigestive tract cancer.
PUBDATE: 19861201
A retrospective review of records and microscopic slides was carried out on 151 patients, encompassing nine specific upper aerodigestive tract cancer sites, correlating depth of invasion with node metastases and outcome. In this preliminary descriptive study, thickness was found to be more closely related to node metastasis and to survival than was surface diameter in middle-stage tumors, particularly in tongue, floor of the mouth, buccal mucosa, gum, and soft palate sites. Thickness, depth of penetration, and bone involvement appear to represent the degree of general tumor aggressiveness better than does surface extent. A substitution of thickness measurement for surface diameter (T) in the present TNM staging system is suggested.

5. DOCID:15304 SCORE: 0.00215353756844571
DOCNO: 3778193
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: A G James AG
PUBTYPE: Journal Article
JOURNALTITLE: Archives of surgery (Chicago, Ill. : 1960)
COUNTRY: UNITED STATES
TITLE: How effective is adjuvant cancer chemotherapy? Lucy Wortham James Clinical Research Award.
PUBDATE: 19861101
Some of the breast cancer chemotherapy trials conducted during the past 25 years were reviewed. In general, most authors noted a significantly improved disease-free survival and overall survival in premenopausal patients but not in postmenopausal patients. Considering all patients, most authors found a significant increase in the disease-free survival but not in overall survival. In one study, the relapse rate increased with time. In the first three years, the relapse rate in the control group greatly exceeded that in the treatment group, but as the years went on, this trend reversed, and an increasing percentage of the treated group had relapse. More time is required to draw firm conclusions.

6. DOCID:15382 SCORE: 0.00205200509917163
DOCNO: 3961438
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
QUALIFIER: mortality
AUTHOR: L Gustafsson L
AUTHOR: S Wall S
AUTHOR: L G Larsson LG
AUTHOR: B Skog B
PUBTYPE: Journal Article
JOURNALTITLE: Scandinavian journal of work, environment & health.
COUNTRY: FINLAND
TITLE: Mortality and cancer incidence among Swedish dock workers--a retrospective cohort study.
PUBDATE: 19860201
The study originates from the arousal of suspicions that, in connection with loading and unloading work involving the use of trucks, exposure to diesel exhaust fumes may be carcinogenic. This report describes a register study in which a broad mapping of the cause-of-death pattern and cancer morbidity has been carried out through the matching of locally compiled personal data with those from a central register, the Cause-of-Death Register, and the Cancer Register. The results obtained thus far show a low total mortality--irrespective of cause of death--but a tendency towards an excess risk for cancer morbidity, mainly due to lung cancer.

7. DOCID:15418 SCORE: 0.00201961457745444
DOCNO: 3208654
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H Qian H
AUTHOR: T R Xu TR
AUTHOR: M Z Zhang MZ
AUTHOR: J Y Li JY
AFFILIATION: Jiangsu Cancer Institute, Nanjing.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Primary non-Hodgkin's lymphoma of the breast--report of 8 cases]
PUBDATE: 19880301
Eight cases of primary Non-Hodgkin's lymphoma (NHL) of the breast are reported. Almost all presented as a painless movable mass without nipple retraction, edema in the overlying skin, satellite skin nodules or bloody nipple discharge. Most of the cases belonged to B cell lymphoma. Wide local excision or simple mastectomy combined with chemotherapy or radiotherapy were adopted in the treatment of these patients. The average survival was 28 months. Since prognosis of NHL is worse than that of breast carcinoma and is easily misdiagnosed as breast cancer, it is important to take vigilance in the differential diagnosis.

8. DOCID:15947 SCORE: 0.0020182228491386
DOCNO: 2763995
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Diet
QUALIFIER: etiology
AUTHOR: M L Slattery ML
AUTHOR: K L Schuman KL
AUTHOR: D W West DW
AUTHOR: T K French TK
AUTHOR: L M Robison LM
AFFILIATION: Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City 84132.
PUBTYPE: Journal Article
JOURNALTITLE: American journal of epidemiology.
COUNTRY: UNITED STATES
TITLE: Nutrient intake and ovarian cancer.
PUBDATE: 19890901
A case-control study was conducted in Utah between 1984 and 1987 to evaluate the effects of nutrient intake on risk of developing ovarian cancer. Detailed dietary intake information was available from 85 first primary ovarian cancer cases and 492 population-based controls. Calories, fat, protein, fiber, and vitamins A and C did not appreciably alter the risk of developing ovarian cancer. However, high intake of beta-carotene appears to confer protection against ovarian cancer (odds ratio = 0.5, 95% confidence interval 0.3-1.0) after adjusting for age, number of pregnancies, and the body mass index of weight/height.

9. DOCID:15139 SCORE: 0.00200258443631787
DOCNO: 3715302
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Menopause
QUALIFIER: diagnostic use
QUALIFIER: diagnosis
AUTHOR: R Erny R
AUTHOR: S Isnard S
AUTHOR: L Boubli L
PUBTYPE: Journal Article
JOURNALTITLE: Revue française de gynécologie et d'obstétrique.
COUNTRY: FRANCE
TITLE: [Progestogen tests after the menopause]
PUBDATE: 19860401
There is virtually no screening for endometrial cancer after the menopause. The methods so-far available (cervico-vaginal smear or endouterine specimens) are either unreliable or else difficult to perform. The progestogen tests are, in contrast, easy for any doctor to carry out, acceptable to patients, fairly reliable and low cost, which should make their widespread use possible. The administration of a progestogen to a post-menopausal woman should not produce bleeding unless the endometrium is hyperplasic or proliferative. 1 366 tests of this type were carried out and resulted, amongst other discoveries, in the detection of 5 cases of asymptomatic cancers of the endometrium and 2 cases of ovarian cancer.

10. DOCID:14989 SCORE: 0.00197774120720893
DOCNO: 2687502
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: Y Yoshizumi Y
AUTHOR: S Shima S
AUTHOR: Y Sugiura Y
AUTHOR: H Yonekawa H
AUTHOR: Y Morisaki Y
AUTHOR: S Tanaka S
AFFILIATION: 2nd Dept. of Surgery, National Defense Medical College.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [A case of resected metastatic adrenal carcinoma from gastric cancer]
PUBDATE: 19891101
A case of a metastatic adrenal carcinoma is presented. A 67-year-old female underwent total gastrectomy for an adenocarcinoma of the stomach before 52 months. A mass was indicated at the left supra-renal region by computed tomography. The mass was successfully resected by an upper abdominal para-aortic lymph node dissection. Histologically, the mass was confirmed as a metastatic adrenal carcinoma with a lymph node metastasis from the gastric cancer. Metastatic adrenal carcinomas and local lymph node dissections for treating metastatic carcinomas are discussed.

11. DOCID:15431 SCORE: 0.00181194813268865
DOCNO: 2447693
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
QUALIFIER: therapeutic use
QUALIFIER: mortality
AUTHOR: D Hickey D
AUTHOR: J Cant J
AUTHOR: M S Soloway MS
AFFILIATION: Department of Urology, University of Tennessee, Memphis.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: Failure of chemotherapy to prolong life in patients with metastatic prostate cancer who have failed androgen deprivation.
PUBDATE: 19880101
Using historical controls, we analyzed the effect of chemotherapy on survival of patients with metastatic prostate cancer who failed androgen deprivation. The survival of 178 patients with metastatic prostate cancer who receive palliation only after failing hormonal therapy was compared with the survival of 27 patients who received chemotherapy on NPCP Protocol 1500. Survival was measured from the initiation of androgen deprivation. The mean survival after chemotherapy was 8.4 months which was slightly less than the group receiving palliation only. At this time, chemotherapy has not been able to improve survival in patients with metastatic prostate cancer.

12. DOCID:14524 SCORE: 0.00175227912464744
DOCNO: 3017663
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: epidemiology
AUTHOR: W K Chen WK
AUTHOR: L Cheng L
AUTHOR: S F Guo SF
AUTHOR: J M Xiang JM
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Serum HSV-2 antibody in males from high and low incidence areas of cervical cancer]
PUBDATE: 19860501
Serum HSV-2 antibody in male from high and low incidence areas of cervical cancer was assayed by enzyme-immuno-slide method. The results show that the geometric mean titer of the serum HSV-2 antibody in the male from high incidence area (413.5) is significantly higher than that from the low incidence area (210.4) (P less than 0.01). It indicates that the high cancer incidence might be related to the high HSV-2 infection rate in the spouses of the cervical cancer patients.

13. DOCID:15852 SCORE: 0.00173268963804998
DOCNO: 2420279
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: Y Kori Y
AUTHOR: M Koyama M
AUTHOR: M Kato M
AUTHOR: Y Honda Y
AUTHOR: Y Kawata Y
AUTHOR: S Arai S
AUTHOR: T Ito T
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Clinical study of chemotherapy (PPM therapy) with cisplatin, peplomycin and mitomycin C in squamous cell lung cancer]
PUBDATE: 19860301
The effect of PPM therapy, consisting of cisplatin, peplomycin and mitomycin C, was evaluated in 15 cases of squamous cell lung cancer. Ten partial responses were achieved in primary cases and the response rate was 66.7%. Nephrotoxicity was well controlled with a continuous infused drip and FOM. The nausea and vomiting were reasonably well controlled with methylprednisolone and metoclopramide. Severe interstitial pneumonitis occurred in 5 cases (33.3%). PPM therapy is considered to be a very useful combination chemotherapy for squamous cell lung cancer but careful attention must be paid to pulmonary toxicity.

14. DOCID:15766 SCORE: 0.00173268645923749
DOCNO: 2605566
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: analysis
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: F Farinati F
AUTHOR: V Lima V
AUTHOR: R Naccarato R
AUTHOR: A J Garro AJ
AFFILIATION: Cattedra Malattie Apparato Digerente, Istituto di Medicina Interna, Policlinico Universitario, Padua, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer letters.
COUNTRY: NETHERLANDS
TITLE: Mutagenic activity in gastric juice and urine of subjects with chronic atrophic gastritis, gastric epithelial dysplasia and gastric cancer.
PUBDATE: 19891201
Gastric juice and urine samples from consecutive patients who underwent endoscopy for upper GI tract complaints were examined for the presence of mutagens. Patients endoscopically and histologically diagnosed as having either chronic atrophic gastritis (CAG) or gastric cancer (GC) had higher than normal levels of mutagens in their gastric juice and urine. The gastric juice pH of these patients was also elevated and, in the case of the CAG patients, contained detectable levels of nitrites. No correlation was however found between gastric mutagen levels and urinary mutagen excretion in the individuals examined.