0. DOCID:11543 SCORE: 0.0029810725656855
DOCNO: 6748237
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: M Nishi M
AUTHOR: H Nomura H
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Problems and present status of surgical treatment for early gastric cancer]
PUBDATE: 19840501
We investigated 81 cases resected in our department about 10 years. The following conclusions were obtained. The R2-operation in lymph node dissection should be made even for early gastric cancer. Early gastric cancer with the unclear border, uneven surface or induration should be operated as advanced cancers. Because the positive rate of lymphatic permeation in these cases is high and the hematogenous metastasis is not rarely found. We also sent out a questionnaire to 430 hospitals which were attached to the Japanese Research Society for gastric cancer. We do believed that we should not easily performed the non operative treatment for early gastric cancer, because we could be only obtained the exact information after the histological examination of resected specimens.


1. DOCID:9531 SCORE: 0.00282399542104053
DOCNO: 6956319
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: R P Morton RP
AUTHOR: P Chapman P
PUBTYPE: Journal Article
JOURNALTITLE: The Australian and New Zealand journal of surgery.
COUNTRY: AUSTRALIA
TITLE: The results of treatment of laryngeal cancer in Auckland New Zealand 1965-1979.
PUBDATE: 19820801
A retrospective review of laryngeal cancer in Auckland over the period 1965-1979 has revealed a generally poorer prognosis for supraglottic cancer than for glottic cancer. The use of radiotherapy for supraglottic cancer and for advanced glottic cancer has not been as successful as primary surgery but has yielded good results in early glottic carcinoma. Salvage surgery after failed radiotherapy was significantly more successful for glottic tumours than supraglottic. Stomal recurrence was more likely if a patient had required an emergency tracheotomy for airway obstruction.


2. DOCID:11364 SCORE: 0.00263374012196465
DOCNO: 6148482
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
AUTHOR: L S Freedman LS
AUTHOR: P Macaskill P
AUTHOR: A N Smith AN
PUBTYPE: Journal Article
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Multivariate analysis of prognostic factors for operable rectal cancer.
PUBDATE: 19840901
Previous reports have established that several variables are of prognostic importance in rectal cancer. The information from a Medical Research Council trial in seventeen centres in the United Kingdom was used to assess the simultaneous contribution of several of these factors in a multivariate analysis. In the preoperative assessment mobility of the tumour and the number of quadrants involved were predictive of the likelihood of a curative resection being possible. Among patients who had curative resections, prognosis was influenced by Dukes' classification, height of tumour, histological grade, and venous invasion. A scoring system based on these criteria was constructed and applied to this group of patients. It successfully defined five prognostic groups with 5-year survival rates ranging from 80% to 19%.


3. DOCID:9611 SCORE: 0.00232604057715253
DOCNO: 3919073
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: surgery
AUTHOR: P L Bailin PL
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of dermatologic surgery and oncology.
COUNTRY: UNITED STATES
TITLE: Lasers in dermatology--1985.
PUBDATE: 19850301
Since the introduction of medical lasers in 1960, the skin has been a major site for applied laser research and therapy. Argon and carbon dioxide lasers have been the most widely used in clinical practice, and many diseases that were impossible or difficult to manage are now being effectively treated with these. Exciting developments today involve other systems, including tunable dye, ruby, neodymium-YAG, and low-energy lasers. Photodynamic therapy for cancer may provide a selective method of destroying clinically inapparent malignant cells. Lasers now seem to have become an integral part of the dermatologic surgeon's armamentarium.


4. DOCID:8853 SCORE: 0.00215620673038577
DOCNO: 6337443
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasm Staging
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: R P Nelson RP
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: New concepts in staging and follow-up of bladder carcinoma.
PUBDATE: 19830201
This article presents new staging systems and methods for properly assessing bladder carcinoma by computerized tomography (CT) scanning and transurethral ultrasound. The practical clinical modalities for following bladder cancer including cytology and random biopsy are presented, in addition to tumor markers. Also, newer methods of detecting recurrence and predicting invasion such as ABO(H) antigen testing, chromosome analysis, and flow cytometry are reviewed in an attempt to understand better the cellular and nuclear abnormalities in malignant transitional cells.


5. DOCID:8337 SCORE: 0.00211029035106562
DOCNO: 6862142
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analogs & derivatives
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: Y Tanio Y
AUTHOR: H Souma H
AUTHOR: Y Tokushima Y
AUTHOR: Y Yamamura Y
AUTHOR: I Azuma I
PUBTYPE: Journal Article
JOURNALTITLE: Gann = Gan.
COUNTRY: JAPAN
TITLE: Regression of line-10 hepatocarcinoma with synthetic quinonyl muramyl dipeptide in strain-2 guinea pigs.
PUBDATE: 19830401
Multiple intralesional injections of quinonylmuramyl dipeptide-66, a new synthetic immunoadjuvant, with a vehicle oil such as squalene or squalane resulted in the regression of line-10 hepatocarcinoma in strain-2 guinea pigs. This chemically synthesized adjuvant should be a useful immunotherapeutic agent for cancer.


6. DOCID:11207 SCORE: 0.0020979589464465
DOCNO: 6594977
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Aclarubicin
DESCRIPTOR: Anthracyclines
QUALIFIER: analogs & derivatives
QUALIFIER: pharmacology
QUALIFIER: drug therapy
AUTHOR: K Tatsuta K
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [New anthracycline antibiotics and derivatives]
PUBDATE: 19841201
Studies of anthracycline antibiotics which have been carried out for the purpose of finding compounds useful in the treatment of cancer are described. Synthetic development of derivatives and analogs which have stronger activities and lower characteristic toxicities than parent antitumor antibiotics such as daunomycin, adriamycin, etc., have been illustrated namely: (1) syntheses of 4'-O-derivatives such as 4'-O-tetrahydropyranyl-adriamycin; (2) syntheses of N-alkyl derivatives such as 3'-deamino-3'-morpholino-adriamycin; and (3) syntheses of 11-deoxy-adriamycin. Notably, 4'-O-tetrahydropyranyl-adriamycin having a (2" R)-configuration has been confirmed to have stronger activity and lower toxicity than adriamycin by Phase II study. New, naturally occurring anthracycline antibiotics (decilorubicin, arugomycin, ditrisarubicin, etc.) have also been reviewed.


7. DOCID:10136 SCORE: 0.00208016715761276
DOCNO: 4039629
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: metabolism
QUALIFIER: chemically induced
AUTHOR: J Trugman J
AUTHOR: H P Hogenkamp HP
AUTHOR: R Roelofs R
AUTHOR: W J Hrushesky WJ
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Cisplatin neurotoxicity: failure to demonstrate vitamin B12 inactivation.
PUBDATE: 19850401
Cisplatin binds in vitro with vitamin B12 coenzymes at physiologic pH and temperature. We have hypothesized that cisplatin-induced neurotoxicity is due to an in vivo inactivation of the cobalamin coenzymes. Vitamin B12 metabolism was studied in patients treated with cisplatin for advanced cancer. Serum levels of B12 and B12-binding capacity remained normal during cisplatin therapy. Excessive urinary excretion of methylmalonic acid and homocystine, which are both metabolic correlates of cellular cobalamin deficiency, was not demonstrated after cisplatin administration. Thus, we find no evidence to implicate cellular B12 deficiency as a mechanism of cisplatin neurotoxicity.


8. DOCID:8645 SCORE: 0.00200434883861574
DOCNO: 6637750
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: U M Kabadi UM
PUBTYPE: Journal Article
JOURNALTITLE: American family physician.
COUNTRY: UNITED STATES
TITLE: Laboratory evaluation of anatomic disorders of the thyroid.
PUBDATE: 19831101
Thyroid function tests, radioiodine uptake and scintiscanning, and antithyroid antibody titers are the main laboratory tests useful in the management of goiter. Scintiscanning and ultrasonography aid in differentiating a functioning adenoma from a "cold" solid nodule--a crucial distinction since the incidence of cancer in a cold nodule is 20 percent. Radioiodine scanning and serum thyroglobulin help in the diagnosis of a well-differentiated thyroid cancer. Serum calcitonin serves as a reliable tumor marker for medullary carcinoma.


9. DOCID:11985 SCORE: 0.0019559042655682
DOCNO: 6846252
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Quality of Life
QUALIFIER: psychology
AUTHOR: B Danoff B
AUTHOR: S Kramer S
AUTHOR: P Irwin P
AUTHOR: A Gottlieb A
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Assessment of the quality of life in long-term survivors after definitive radiotherapy.
PUBDATE: 19830601
An interview questionnaire was developed to assess quality of life both in objective and subjective terms in cancer patients. Standardized measures were employed and allowed for comparison with a national baseline. Three hundred thirty-nine patients who were alive without evidence of disease 3 or more years following initial treatment were interviewed. There was no difference in terms of educational level, marital status, or satisfaction with local government, family, job, friends, community, health, recreation, or activities when compared to the age-adjusted national baseline. The patients were more satisfied with region, self, and life as a whole. There was no evidence of a diminished quality of life in these patients.


10. DOCID:8836 SCORE: 0.00189385058642439
DOCNO: 3967136
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mastectomy
DESCRIPTOR: Neoplasm Recurrence, Local
QUALIFIER: surgery
AUTHOR: S J Nixon SJ
AUTHOR: R J Steele RJ
AUTHOR: A R Hawkins AR
AUTHOR: J McGregor J
AUTHOR: A P Forrest AP
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of surgery.
COUNTRY: ENGLAND
TITLE: Prediction of recurrence after mastectomy for operable breast cancer.
PUBDATE: 19850101
A patient's risk of early recurrence after mastectomy for breast cancer has been estimated by using a combination of four prognostic factors. A computer program, designed to calculate the exact probability of recurrence within 2 years of mastectomy, was accurate when tested on 240 patients. A simple scoring system could identify patients at lower and greater risk than any single factor alone.


11. DOCID:9579 SCORE: 0.00187206999155259
DOCNO: 6339220
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Carcinogens, Environmental
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: R A Cartwright RA
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Historical and modern epidemiological studies on populations exposed to N-substituted aryl compounds.
PUBDATE: 19830301
The historical exposures to aromatic amines of various occupational groups are briefly reviewed. Modern studies indicate that other occupational groups might have risks worth investigating; these include machinists and workers in the chemical industry. Details of a recent investigation into the exposure of dye workers are given which indicate a lowered risk in recent years since the introduction of safety measures. Nonoccupational exposures to the aromatic amines are also discussed. They include cigarette smoking and phenacetin abuse, the former being a potent causal agent in bladder cancer.


12. DOCID:11242 SCORE: 0.00186193073754846
DOCNO: 7151272
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
AUTHOR: I D Capel ID
AUTHOR: E P Spencer EP
AUTHOR: A E Daivies AE
AUTHOR: H N Levitt HN
PUBTYPE: Journal Article
JOURNALTITLE: Clinical biochemistry.
COUNTRY: CANADA
TITLE: The assessment of zinc status by the zinc tolerance test in various groups of patients.
PUBDATE: 19821001
The zinc status of young and aged subjects, hypertensives, geriatric patients with leg ulcers and cancer patients has been determined by various means. Serum, saliva, urine and hair zinc were measured by atomic absorption spectrometry and no correlation was observed between the zinc levels in any of these differing matrices. The mean hair and salivary zinc level showed little variation between the differing groups of patients and provided little or no indication of zinc status. The results of the present experiment indicate that the zinc tolerance test, that is, an unequivocal rise in serum zinc following per oral administration of this metal, provides the best indication of zinc status.


13. DOCID:9166 SCORE: 0.00183577571141681
DOCNO: 6834536
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Castration
QUALIFIER: surgery
AUTHOR: B W Snow BW
AUTHOR: R G Rowland RG
AUTHOR: J P Donohue JP
AUTHOR: L H Einhorn LH
AUTHOR: S D Williams SD
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Review of delayed orchiectomy in patients with disseminated testis tumors.
PUBDATE: 19830301
Of 8 patients who underwent delayed orchiectomy after adequate chemotherapy for metastatic testicular cancer 7 had no evidence of disease at the time of orchiectomy but 3 had residual cancer in the testis removed. The testis may be a privileged sanctuary for malignancy even during treatment with appropriate chemotherapy. Therefore, the primary tumor should be removed in patients presenting initially with metastatic disease, even if the metastases clear with treatment.


14. DOCID:10949 SCORE: 0.00179527027967377
DOCNO: 6697299
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ear, Middle
QUALIFIER: epidemiology
AUTHOR: R P Morton RP
AUTHOR: P M Stell PM
AUTHOR: P P Derrick PP
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Epidemiology of cancer of the middle ear cleft.
PUBDATE: 19840401
Cancer of the middle ear is an uncommon tumor which has a very poor prognosis. A population-based analysis shows that there are two marked differences between men and women for middle ear cancer in England and Wales: (1) the incidence rate in men continues to rise with advancing age, but in women the rise is proportionately much less after 75 years of age; and (2) the mortality rate in men decreases after 70 to 75 years of age, whereas the mortality for women continues to rise with advancing age. The significance of these differences is not yet clear. No other epidemiologic reports related to middle ear cancer has been found in the literature.