0. DOCID:21507 SCORE: 0.0020830120263356
DOCNO: 8607689
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pneumonectomy
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: K Yokoi K
AUTHOR: N Miyazawa N
AUTHOR: G Imura G
AFFILIATION: Division of Thoracic Surgery, Tochigi Cancer Center, Utsunomiya, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Annals of thoracic surgery.
COUNTRY: UNITED STATES
TITLE: Isolated incisional recurrence after curative resection for primary lung cancer.
PUBDATE: 19960401
We present a long-term survivor with isolated recurrent tumor in the incisional scar that developed 9 months after a curative resection for primary lung adenocarcinoma. She underwent an excision of the tumor followed by systemic chemotherapy, and is currently alive with no evidence of disease 69 months after the recurrence. Isolated incisional recurrence after complete resection of lung cancer is a rare phenomenon and may be curable using multimodal treatment.


1. DOCID:22907 SCORE: 0.0017766784698751
DOCNO: 8668056
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Catheters, Indwelling
QUALIFIER: methods
AUTHOR: A Teh A
AUTHOR: K W Leong KW
AFFILIATION: Department of Medicine, University Hospital, Kuala, Lumpur.
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Malaysia.
COUNTRY: MALAYSIA
TITLE: Insertion of Hickman catheters by the percutaneous technique.
PUBDATE: 19951201
Hickman catheters have previously been conventionally placed by surgical dissection. This usually performed by experienced surgeons and is carried out under general anaesthesia. We report our preliminary experience in Hickman catheter placement by percutaneous technique in twenty patients. We outline the implantation methods and complications encountered by this technique. The procedure is relatively simple provided the operator is skilled in central venous cannulation. The chief advantages are that the procedure can be done under local anaesthesia and results in less trauma compared with surgical dissection. Such an alternative in catheter insertion would promote wider usage of Hickman catheters in cancer patients.


2. DOCID:22495 SCORE: 0.00116414477474911
DOCNO: 7721160
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
QUALIFIER: therapy
QUALIFIER: mortality
QUALIFIER: therapy
AUTHOR: A Roszak A
AFFILIATION: Instytutu Ginekologii i Połoznictwa A.M. im. K. Marcinkowskiego w Poznaniu.
PUBTYPE: Journal Article
JOURNALTITLE: Ginekologia polska.
COUNTRY: POLAND
TITLE: [Prognostic survival of women after surgery for endometrial cancer]
PUBDATE: 19940901
The influence a few factors on prognosis on 5-th year survival has been estimated in 367 patients with endometrial cancer with stage I, II and III disease which underwent surgery and radiotherapy. The stage is the most important and competent authority indicators of prognosis on 5-th year survival, among prognostic variables for endometrial carcinoma the most important have been identified as: 1) histologic type, 2) grading, 3) depth of myometrial invasion. The 5 year survival appeared correlated with the age of patients survival of patients younger than 59 years of age was higher and statistically significant.


3. DOCID:23010 SCORE: 0.00115832931076396
DOCNO: 7731646
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: physiology
AUTHOR: B Zumoff B
AFFILIATION: Department of Medicine, Beth Israel Medical Center, New York, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Obstetrics and gynecology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Hormonal profiles in women with breast cancer.
PUBDATE: 19941201
The literature findings on endogenous hormonal profiles in women with breast cancer are reviewed in detail. It is concluded that four sets of findings are valid: (1) diminished adrenal androgen production, probably genetic, in women with premenopausal breast cancer; (2) ovarian dysfunction (luteal inadequacy plus increased testosterone production) in breast cancer at all ages; (3) increased 16 alpha-hydroxylation of estradiol in breast cancer at all ages; and (4) evidence that prolactin is a permissive risk factor for breast cancer, and that the pregnancy-induced decrease in prolactin levels may account for the protective effect of early pregnancy against breast cancer.


4. DOCID:21704 SCORE: 0.000857706521427443
DOCNO: 7853556
AUTHOR: W A Hübner WA
AUTHOR: H Pflüger H
AFFILIATION: Department of Urology, Lainz Hospital, Vienna, Austria.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Functional replacement of bladder and urethra after cystectomy for bladder cancer in a female patient.
PUBDATE: 19950301
We describe a new concept for female bladder replacement introducing an ileocecal pouch with the intact appendix vermiformis used as an orthotopic neourethra. Based upon the results of preceding experimental studies this procedure was performed on a woman with the diagnosis of focal invasive bladder cancer. Eight months after the operation the patient is completely continent and back to work. This new type of urinary diversion with improved body image can be offered to female patients undergoing cystectomy for bladder cancer.


5. DOCID:22017 SCORE: 0.000857703377678357
DOCNO: 7623868
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Germ-Line Mutation
DESCRIPTOR: Models, Genetic
DESCRIPTOR: Mutagenicity Tests
QUALIFIER: toxicity
QUALIFIER: toxicity
AUTHOR: J Favor J
AUTHOR: D Layton D
AUTHOR: G Sega G
AUTHOR: J Wassom J
AUTHOR: J Burkhart J
AUTHOR: G Douglas G
AUTHOR: K Dearfield K
AUTHOR: D Brusick D
AFFILIATION: Hazleton Washington Inc., Vienna, VA 22182-1699, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Mutation research.
COUNTRY: NETHERLANDS
TITLE: International Commission for Protection Against Environmental Mutagens and Carcinogens. Genetic risk extrapolation from animal data to human disease. A Taskgroup Report. No. 00105.
PUBDATE: 19950801
This report describes a model for producing quantitative genetic risk assessments for human populations. The model is patterned after current methods used in cancer risk analysis. The risk to humans is expressed as the number of additional dominant genetic diseases added to the existing genetic burden, in the offspring of the exposed individuals.


6. DOCID:23172 SCORE: 0.000857702616200637
DOCNO: 7548842
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: pathology
QUALIFIER: therapy
AUTHOR: T J McDonnell TJ
AUTHOR: R E Meyn RE
AUTHOR: L E Robertson LE
AFFILIATION: Department of Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston 77030, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: UNITED STATES
TITLE: Implications of apoptotic cell death regulation in cancer therapy.
PUBDATE: 19950201
The process of programmed cell death, or apoptosis, is now recognized as an important component of multistep carcinogenesis. Traditionally, interventions used in the treatment of cancer patients were predicated on enhanced rates of proliferation in the tumor cells. It is now appreciated that tumor growth may, in many circumstances, be more a function of reduced rates of cell death rather than enhanced proliferation per se. Our understanding of the molecular regulation of apoptotic cell death is leading to the design and implementation of treatment strategies based on cell death induction.


7. DOCID:23976 SCORE: 0.000857608732390501
DOCNO: 8002975
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: analysis
AUTHOR: T J Yeatman TJ
AUTHOR: W Mao W
AUTHOR: R C Karl RC
AUTHOR: J Y Djeu JY
AFFILIATION: Department of Surgery, H. Lee Moffitt Cancer Center, University of South Florida, Tampa.
PUBTYPE: Journal Article
JOURNALTITLE: Biochemical and biophysical research communications.
COUNTRY: UNITED STATES
TITLE: Phospholipase C-gamma 1 is present on the surface of human colorectal cancer cells.
PUBDATE: 19940601
Using murine monoclonal antibodies, we have detected the novel signal transducing enzyme, phospholipase C-gamma 1, on the surface of cultured human colorectal cancer cells. We have also demonstrated the presence of this enzyme on the surface of fresh human tumor cells derived from primary and metastatic colorectal tumors. This enzyme has previously been described to be associated only with the inner face of the plasma membrane and the cell cytosol. The finding of an enzyme critical to the signal transduction pathway may have important implications for additional functions of this protein.


8. DOCID:22572 SCORE: 0.000857341137313797
DOCNO: 7489308
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Contrast Media
DESCRIPTOR: Image Enhancement
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: diagnosis
AUTHOR: C W Piccoli CW
AFFILIATION: Department of Radiology, Jefferson Medical College, Philadelphia, Pennsylvania, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Magnetic resonance imaging clinics of North America.
COUNTRY: UNITED STATES
TITLE: The specificity of contrast-enhanced breast MR imaging.
PUBDATE: 19941101
The sensitivity of contrast-enhanced breast MR imaging for malignancy is close to 100%, an improvement over traditional methods of cancer detection. The reported specificity of breast MR imaging, however, ranges from approximately 37% to 97%. This range of values is the result of differences in technique and diagnostic criteria. The variation in biologic activity and vascularity of benign and malignant lesions, as well as normal tissue, also complicates MR imaging diagnosis. A review of breast MR imaging research with an emphasis on specificity issues is also presented.


9. DOCID:22532 SCORE: 0.00085727720577754
DOCNO: 9230688
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Anaphase
DESCRIPTOR: Schizosaccharomyces pombe Proteins
QUALIFIER: physiology
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: Y Nakaseko Y
AUTHOR: M Yanagida M
AFFILIATION: Department of Biophysics, Graduate School of Science, Kyoto University, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: BioEssays : news and reviews in molecular, cellular and developmental biology.
COUNTRY: ENGLAND
TITLE: A telomerase mutant defective in sister chromatid separation at mitosis.
PUBDATE: 19970701
The telomere is a functional domain of the chromosome, located at the extreme ends, and is essential for normal chromosome stability. Chromosomes lacking telomeres are inherited improperly, and mutations in the telomeric repeat sequences are thought to lead to senescence and possibly to cancer. The molecular mechanisms maintaining chromosomes by telomeres, however, have been unclear. Results recently reported by Kirk et al, offer an insight into new telomerase function. They have identified a novel telomerase mutation that blocks sister chromatid separation in mitosis.


10. DOCID:23152 SCORE: 0.000552700017422904
DOCNO: 8697117
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: nursing
AUTHOR: A T Nally AT
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: AACN clinical issues.
COUNTRY: UNITED STATES
TITLE: Critical care of the patient with lung cancer.
PUBDATE: 19960201
Critical care of patients with lung cancer requires a knowledge of the behavior of this malignancy and the implications of several prognostic variables. Lung cancer's location, cellular characteristics, and metastatic patterns predispose patients to many emergencies that may require critical care intervention. In this article, the author presents important background on the behavior of this malignancy, its treatment, and predicted critical care problems. Included is a discussion of complications such as spinal cord compression, superior vena cava syndrome, airway obstruction, pleural effusions, and neoplastic cardiac tamponade, with an overview of common paraneoplastic syndromes. A case study exemplifies a possible presentation and management of a patient with lung cancer and some of these complications.


11. DOCID:20595 SCORE: 0.000552336641749249
DOCNO: 7766365
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: methods
AUTHOR: D M Welsh DM
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Critical care nursing clinics of North America.
COUNTRY: UNITED STATES
TITLE: Hyperthermia treatment of malignant brain tumors.
PUBDATE: 19950301
Although the use of heat in cancer therapy is not a new concept, recent advances in technology have allowed refinement and revival of this useful modality. This article reviews the biologic basis for heating, the rationale for combining hyperthermia with other brain tumor therapies, and various methods used to produce hyperthermia in brain tumor treatment. Unique challenges in the nursing care of brain tumor patients undergoing hyperthermia therapy also are discussed.


12. DOCID:20825 SCORE: 0.000552271457185612
DOCNO: 7574754
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: S Mukai S
AUTHOR: T Fujisaki T
AUTHOR: N Sato N
AFFILIATION: Dept. of Surgery, Kosei General Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Preoperative intra-arterial chemotherapy with THP-ADR for locally advanced breast cancer]
PUBDATE: 19950901
We treated 8 patients of Stage III and IV breast cancer preoperatively with THP-ADR intra-arterial infusion chemotherapy. The median dose was 200 mg with a range from 150 to 310 mg. The response rate of THP was 75.0% compared to 66.7% of ADR. Leucopenia was observed during THP treatment with a lower frequency of alopecia.


13. DOCID:21005 SCORE: 0.000552095573537269
DOCNO: 7533118
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: W R Staggers WR
AUTHOR: A J Paterson AJ
AUTHOR: J E Kudlow JE
AFFILIATION: Department of Medicine, University of Alabama at Birmingham 35294.
PUBTYPE: Journal Article
JOURNALTITLE: Gene.
COUNTRY: NETHERLANDS
TITLE: Sequence of the functional human keratin K14 promoter.
PUBDATE: 19950201
The K14 keratin is an intermediate filament produced in squamous epithelia. This tissue-specific expression is directed by the promoter (pK14) of the K14 gene which has been used extensively to direct the expression of transgenes to the skin. Human K14 was cloned and the upstream sequence is presented. In transient transfections, pK14 directs expression of a luciferase reporter in keratinocytes much more potently than in breast cancer cells.


14. DOCID:20837 SCORE: 0.000551927633223602
DOCNO: 8199500
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Attitude to Health
DESCRIPTOR: Family Practice
DESCRIPTOR: Patient Acceptance of Health Care
QUALIFIER: prevention & control
QUALIFIER: psychology
AUTHOR: J A Hammond JA
AUTHOR: M Stewart M
AFFILIATION: Department of Family Medicine, University of Western Ontario.
PUBTYPE: Journal Article
JOURNALTITLE: Canadian family physician Médecin de famille canadien.
COUNTRY: CANADA
TITLE: Female patients' attitudes to mammography screening.
PUBDATE: 19940301
This study compares the attitudes of women who chose or chose not to have mammography screening. Women personally invited by their physicians to have mammography were more likely to go for screening. Those who did not go for screening were more afraid of medical tests and were less likely to want to know whether they had cancer.