0. DOCID:7182 SCORE: 0.00374853599185949
DOCNO: 420252
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J R Koransky JR
AUTHOR: M D Stargel MD
AUTHOR: V R Dowell VR
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of medicine.
COUNTRY: UNITED STATES
TITLE: Clostridium septicum bacteremia. Its clinical significance.
PUBDATE: 19790101
The medical records of 59 patients with Clostridium septicum bacteremia were reviewed; 42 (71 per cent) of these patients had malignancies. One half had hematologic malignancies, and one half had solid tumors. Of the 21 patients with solid tumors, 14 (67 per cent) had cancer of the colon. Among these patients, the cecum was the most frequent site of malignancy. The cecum and distal ileum were the most probable portals of entry for C. septicum bacteremia among the 28 patients examined at autopsy. Patients admitted to the hospital with C. septicum bacteremia usually have fulminating clinical courses and, unless the appropriate antibiotics are administered soon after admission, the outcome is fatal. The results of this study demonstrate the high association of C. septicum bacteremia and malignancy, and the need for early recognition and therapy.


1. DOCID:5899 SCORE: 0.00360300279319257
DOCNO: 87253
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnostic use
QUALIFIER: diagnostic use
QUALIFIER: radionuclide imaging
AUTHOR: J M Woolfenden JM
AUTHOR: D S Alberts DS
AUTHOR: J N Hall JN
AUTHOR: D D Patton DD
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Cobalt-57 bleomycin for imaging head and neck tumors.
PUBDATE: 19790501
Cobalt-57 bleomycin imaging was performed in 11 patients with a history of head and neck cancer. Clinical and scan findings concurred on the presence and extent of tumor in 9 patients (82%); tumor was present in 7 and absent in 2 of the 9. In 2 patients (18%) the scan demonstrated tumor in the neck but failed to show metastatic sites. Cobalt-57 bleomycin images were of good technical quality, with remarkably low background activity at 24 hours after administration. Cobalt-57 bleomycin imaging appears to be a promising technique for evaluating patients with head and neck tumors.


2. DOCID:3748 SCORE: 0.00354715091774751
DOCNO: 1152159
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
AUTHOR: S Brosman S
AUTHOR: M Hausman M
AUTHOR: S Shacks S
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Immunologic alterations in patients with prostatic carcinoma.
PUBDATE: 19750601
The state of cell-mediated immunity was evaluated in 41 patients with prostatic carcinoma by determining their ability to demonstrate delayed cutaneous hypersensitivity with dinitrochlorobenzene and recall antigens, and to mount an inflammatory response to croton oil, as well as by measuring changes in monocyte chemotactic response. The patients were divided into 2 groups: those with localized disease and those with metastatic carcinoma. Monocyte chemotactic response provides an in vitro quantitative measure of effector cell function and was significantly depressed in the entire group of prostatic cancer patients as compared to non-cancer controls (p less than 0.05). Patients with metastatic carcinoma had a greater defect than those with localized disease (p less than 0.025). After radical prostatectomy a group of patients with localized disease tended to show improvement in monocyte chemotactic response (p less than 0.025). The ability of patients to develop a delayed cutaneous hypersensitivity response was impaired and correlated with the clinical stage of the disease. By using the cutaneous irritant, croton oil, the ability of these cancer patients to mount an inflammatory response was also found to be impaired and showed a close correlation between clinical stage and course of disease. Changes in response to croton oil tended to precede alterations in dinitrochlorobenzene response.


3. DOCID:3247 SCORE: 0.00204481910826996
DOCNO: 1192362
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
QUALIFIER: genetics
AUTHOR: S Kakati S
AUTHOR: I Hayata I
AUTHOR: M Oshimura M
AUTHOR: A A Sandberg AA
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Chromosomes and causation of human cancer and leukemia. X. Banding patterns in cancerous effusions.
PUBDATE: 19751101
Cells from five cancer effusions (two ovarian carcinomas, two lung cancers, and one carcinoma of the breast) were analyzed by G-, C-, and Q-banding techniques. The following observations were made: 1) The origin of some marker chromosomes could be traced accurately by these banding techniques. 2) Several chromosomes, which appeared normal with conventional staining techniques, were found to be re-arranged ones and, hence, abnormal. 3) Chromosomes No. 1, No. 3 and No. 11 were the most frequently involved in aberrations, whereas No. 12, No. 13, No. 17-20, and No. 22 Were least frequently involved. Only in one case each was the X chromosome or the Y chromosome involved in aberrations. The Y chromosome was found to be missing in all cancer cells of one lung cancer. 4) Each effusion had characteristic markers, invariably present in each cell, whether the cells were near diploid, or polyploid. 5) No common markers were observed in the two ovarian carcinomas studied, whereas the two lung cancers had a few common markers.


4. DOCID:7339 SCORE: 0.00175836714533039
DOCNO: 665664
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: A B Miller AB
AUTHOR: A Kelly A
AUTHOR: N W Choi NW
AUTHOR: V Matthews V
AUTHOR: R W Morgan RW
AUTHOR: L Munan L
AUTHOR: J D Burch JD
AUTHOR: J Feather J
AUTHOR: G R Howe GR
AUTHOR: M Jain M
PUBTYPE: Journal Article
JOURNALTITLE: American journal of epidemiology.
COUNTRY: UNITED STATES
TITLE: A study of diet and breast cancer.
PUBDATE: 19780601
A case-control study has been conducted in four areas in Canada in which 40 cases of breast cancer matched by age and marital status with neighborhood controls were administered a medical and dietary history questionnaire, a 24-hour recall of dietary information and a four-day diet record. The Study has produced evidence of an association between an increased intake of nutrients, especially total fat, in both pre-menopausal and post-menopausal women with breast cancer. Reasons why a weak association might have been anticipated are discussed, and it is concluded that in reality the association is stronger. Furthermore, its consistency with other evidence, both experimental and international, suggests that it is causal.


5. DOCID:2596 SCORE: 0.00174410322253891
DOCNO: 300279
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: A Saxon A
AUTHOR: J Portis J
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: Lymphoid subpopulation changes in regional lymph nodes in squamous head and neck cancer.
PUBDATE: 19770401
Lymph nodes from 10 normal patients and regional lymph nodes (RLN) from 19 patients with squamous cancer of the head and neck were evaluated as to their lymphoid subpopulations. In comparison to normal lymph nodes, RLN from cancer patients demonstrated a marked increase in the proportion of cells with membrane immunoglobulin, the receptor for the third component of complement, and the receptor for the Fc portion of immunoglobulin G. The increased Fc receptor cells were not Fc-bearing thymus-derived lymphocytes, inasmuch as they separated with the non-sheep erythrocyte-lymphocyte rosette-forming population. The overall thymus-derived lymphocyte percentage in RLN was proportionally decreased. A transition from the normal lymph node composition to the altered lymphocyte profile seen in RLN was demonstrated on moving from distal lymph nodes to RLN within the lymphatic drainage of a tumor. Lymph nodes involved with tumor also showed the pattern of bursa equivalent cell population increases.


6. DOCID:3585 SCORE: 0.00174400181795057
DOCNO: 200253
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: R A Hawkins RA
AUTHOR: A Hill A
AUTHOR: B Freedman B
AUTHOR: S M Gore SM
AUTHOR: M M Roberts MM
AUTHOR: A P Forrest AP
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Reproducibility of measurements of oestrogen-receptor concentration in breast cancer.
PUBDATE: 19770901
The reproducibility of measurements of oestrogen-receptor activity has been examined in multiple specimens from a rabbit uterus, a rat mammary tumour and human breast tumours. The relationship between receptor concentration and tumour histology has also been investigated in 11 large primary tumours. In the animal tissues, receptor measurements were relatively reproducible (coefficient of variance: wet wt. basis 16-17%, protein basis 16-21%) but in human breast tumours receptor activity varied considerably (c.v.: wet wt. basis, 22-125%; protein basis, 28-72%). In addition to these variations in receptor activity within tumours, there was a difference between tumours, as demonstrated by an analysis of variance (P less than 0.01). In the 11 primary breast cancers selected for study, the level of receptor activity was related to menopausal status and the tumour content of the specimen. We conclude that the receptor activity detected varies within a tumour and depends upon the tumour content of the biopsy specimen. Predictions based on precise quantitation of receptor concentrations may therefore necessitate replicate tumour sampling and correction for the fraction of non-tumour tissue in each sample.


7. DOCID:6937 SCORE: 0.00145762472388491
DOCNO: 6255626
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: A Gabler A
AUTHOR: S Liebig S
PUBTYPE: Journal Article
JOURNALTITLE: Thorax.
COUNTRY: ENGLAND
TITLE: Reoperation for bronchial carcinoma.
PUBDATE: 19800901
After a primary operation for bronchial carcinoma, 17 patients underwent reoperation for local recurrence or intrathoracic metastasis (nine squamous cell, five alveolar cell, and three adenocarcinomas). The average interval between the first and second operation was 23 months (range: six to 48 months). Twelve patients had a pneumonectomy after an initial ipsilateral lobectomy. Five patients underwent contralateral wedge excision after initial lobectomy or wedge excision. Three patients died within 30 days of the reoperation. Eight of the remaining 14 patients died subsequently, the time of survival averaging 18 months (range: three to 54 months). Six patients are still alive, two having survived their reoperation for more than five years. Reoperation for recurrent bronchial carcinoma is rarely performed, but it should be considered in all cases where patients survive operation for lung cancer if the primary operation was thought to be radical.


8. DOCID:3955 SCORE: 0.00144344208569866
DOCNO: 132791
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Documentation
DESCRIPTOR: Neoplasms
DESCRIPTOR: Periodicals
AUTHOR: L Sandor L
AUTHOR: R P Kraft RP
AUTHOR: G Wagner G
AUTHOR: R G Henzler RG
AUTHOR: M Wolff-Terroine M
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Krebsforschung und klinische Onkologie. Cancer research and clinical oncology.
COUNTRY: GERMANY, WEST
TITLE: Analysis of the structure of cancer literature based on SABIR-C. III. A survey of the distribution of the world oncological publications from 1969-1974.
PUBDATE: 19760601
The great number of disciplines involving oncology and the exponential growth in the number of publications make it increasingly more difficult to keep abreast of the important oncological literature appearing in a large number of periodicals. It is, therefore, essential for the oncologist to be up to date with the journals and to read the papers relevant to his specialty. The cancer literature information system SABIR-C developed by the French and German Cancer Research Centers was created for this purpose. The present paper analyses 54496 papers published in periodicals covered by the SABIR-C system in the period from January 1969 to October 1974. The tables included contain the titles of periodicals which are of particular relevance for cancer research. They permit a quick orientation with regard to the important sources of oncological publications. These tables also assist the librarian working in a cancer research institution in selecting the most important and quantitatively most productive periodicals. This is especially important since he usually has only limited financial resources at his disposal. Further tables give a survey of the countries of origin and the categories to which the latest oncological literature belongs.


9. DOCID:2133 SCORE: 0.00144339264242082
DOCNO: 903152
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosomes, Human, 1-3
DESCRIPTOR: Heterochromatin
QUALIFIER: genetics
AUTHOR: N B Atkin NB
AUTHOR: V J Pickthall VJ
PUBTYPE: Journal Article
JOURNALTITLE: Human genetics.
COUNTRY: GERMANY, WEST
TITLE: Chromosomes 1 in 14 ovarian cancers. Heterochromatin variants and structural changes.
PUBDATE: 19770801
Structurally rearranged chromosomes 1 were found in 9 out of 14 ovarian carcinomas and may also have been present in three others. In the remaining two, pericentric inversions involving the heterochromatic regions of chromosomes 1 were seen, and were also identified in one of the chromosomes 1 in the patient's normal cells (lymphocytes). Altogether, heterochromatin variants (variation in size and/or the presence of a pericentric inversion) were seen in the tumour cells of eight cases, and one or both types of variation were identified in the normal cells of six of these. The possibility of an association between the presence of chromosome 1 heterochromatin variants as a constitutional anomaly, a liability to ovarian (and perhaps other forms of) cancer and structural changes involving the chromosomes 1 in the tumour cells is considered.


10. DOCID:5555 SCORE: 0.00115290363096842
DOCNO: 505219
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Wound Healing
QUALIFIER: methods
QUALIFIER: instrumentation
QUALIFIER: surgery
AUTHOR: M S Elliot MS
AUTHOR: E J Immelman EJ
AUTHOR: P J Stevens PJ
PUBTYPE: Journal Article
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Management of the perineal wound with constant irrigation and suction after abdominoperineal excision for cancer of the rectum. A new suction/irrigation drain.
PUBDATE: 19791101
The technique of primary closure of the perineal wound combined with continuous irrigation and suction of the operative site has been used in 21 patients who underwent abdominoperineal excision for cancer of the rectum or anal canal. Primary healing occurred in 19 patients within 18 days, and all patients healed within 2 months. These results are in marked contrast to those in 38 patients treated with constant suction alone, of whom only 17 healed primarily.


11. DOCID:6764 SCORE: 0.00115285462792866
DOCNO: 6159063
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: H B Krebs HB
AUTHOR: R E Girtanner RE
AUTHOR: S R Nordqvist SR
AUTHOR: I Mineau I
AUTHOR: B F Helmkamp BF
AUTHOR: H E Averette HE
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Treatment of advanced cervical cancer by combination of bleomycin and mitomycin-C.
PUBDATE: 19801101
A combination of bleomycin and mitomycin-C, reported as extraordinarily effective in a previous clinical trial, was used to treat 20 patients with advanced cervical cancer. Seven partial remissions (35%) and one complete remission (5%) were observed. Six of the partial remissions were of short duration (less than four months); the only patient with complete remission was still alive without evidence of disease ten months after initiation of chemotherapy. Nonresponders had a mean survival time of 6.6 months and responders 8.0 months. The treatment results confirm some efficacy of the drug regimen, although in our hands it did not live up to the high expectations raised by others.


12. DOCID:6130 SCORE: 0.00115255810048536
DOCNO: 6168008
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: N Grasso N
PUBTYPE: Journal Article
JOURNALTITLE: La Radiologia medica.
COUNTRY: ITALY
TITLE: [On some cystographic appearances of prostatic pathology (author's transl)]
PUBDATE: 19810501
The author reports a personal series of 200 cases of prostatic pathology studied by perfusional urography and by radio-urological instrumental methodics. He considers, especially, some radiographic appearances of involvement of the vesical floor, correlating them with clinic and gross pathology. Thus he pointed out that: the marks on the vesical floor with the aspect of "spread wings" is the most frequent radiographic pattern showing the chronic prostatitis; "the endovesical lacuna" is disregarded aspect of medium lobe's hypertrophy, as well as the "raising as tent" of the vesical floor due probably to an hyposphincteric periurethral adenoma. Although the mameloned aspect of vesical floor is typical, only sometimes it is the sign of an early cancer of the superior face of the prostate.


13. DOCID:7830 SCORE: 0.00115186276548482
DOCNO: 715632
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: blood
AUTHOR: A Van Den Heever A
AUTHOR: F J Pretorius FJ
AUTHOR: G Falkson G
AUTHOR: I W Simson IW
PUBTYPE: Journal Article
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Hepatitis B surface antigen and primary liver cancer.
PUBDATE: 19780801
Sera of 184 patients were examined to determine the incidence of hepatitis B surface antigen (HBsAg). Ninety-two patients had primary liver cancer (PLC) and there were 92 matched controls. Thirty-one of the 92 patients with PLC and 8 of the 92 patients with no clinical evidence of liver disease had radio-immunoassay-positive tests for HBsAg. The difference was significant (P less than 0,01). In 56 of the patients with PLC it was possible to assess the nature of associated liver disease histologically. HBsAg was found in the sera of 66,6% of patients with postcollapse cirrhosis and in 22,2% of patients with chronic Budd-Chiari syndrome. It is likely that the role played by hepatitis B infection in the pathogenesis of PLC varies according to local circumstances in different geographical areas.


14. DOCID:240 SCORE: 0.00114261900572933
DOCNO: 1234628
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: therapeutic use
AUTHOR: H J Buchsbaum HJ
AUTHOR: W C Keettel WC
PUBTYPE: Journal Article
JOURNALTITLE: National Cancer Institute monograph.
COUNTRY: UNITED STATES
TITLE: Radioisotopes in treatment of stage Ia ovarian cancer.
PUBDATE: 19751001
The role of radioisotopes in the treatment of ovarian carcinoma is discussed. The University of Iowa experience with prophylactic treatment of stage Ia ovarian cancer with radiogold is presented. Cumulative survival in 56 patients with epithelial cancers was 94.3%. In a prospective study, we compare the use of radiogold and total abdominal irradiation in the treatment of stage Ia ovarian carcinoma.