0. DOCID:7182 SCORE: 0.00374853599185949
DOCNO: 420252
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J R Koransky JR
AUTHOR: M D Stargel MD
AUTHOR: V R Dowell VR
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of medicine.
COUNTRY: UNITED STATES
TITLE: Clostridium septicum bacteremia. Its clinical significance.
PUBDATE: 19790101
The medical records of 59 patients with Clostridium septicum bacteremia were reviewed; 42 (71 per cent) of these patients had malignancies. One half had hematologic malignancies, and one half had solid tumors. Of the 21 patients with solid tumors, 14 (67 per cent) had cancer of the colon. Among these patients, the cecum was the most frequent site of malignancy. The cecum and distal ileum were the most probable portals of entry for C. septicum bacteremia among the 28 patients examined at autopsy. Patients admitted to the hospital with C. septicum bacteremia usually have fulminating clinical courses and, unless the appropriate antibiotics are administered soon after admission, the outcome is fatal. The results of this study demonstrate the high association of C. septicum bacteremia and malignancy, and the need for early recognition and therapy.

1. DOCID:5899 SCORE: 0.00360300279319257
DOCNO: 87253
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnostic use
QUALIFIER: diagnostic use
QUALIFIER: radionuclide imaging
AUTHOR: J M Woolfenden JM
AUTHOR: D S Alberts DS
AUTHOR: J N Hall JN
AUTHOR: D D Patton DD
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Cobalt-57 bleomycin for imaging head and neck tumors.
PUBDATE: 19790501
Cobalt-57 bleomycin imaging was performed in 11 patients with a history of head and neck cancer. Clinical and scan findings concurred on the presence and extent of tumor in 9 patients (82%); tumor was present in 7 and absent in 2 of the 9. In 2 patients (18%) the scan demonstrated tumor in the neck but failed to show metastatic sites. Cobalt-57 bleomycin images were of good technical quality, with remarkably low background activity at 24 hours after administration. Cobalt-57 bleomycin imaging appears to be a promising technique for evaluating patients with head and neck tumors.

2. DOCID:3748 SCORE: 0.00354715091774751
DOCNO: 1152159
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
AUTHOR: S Brosman S
AUTHOR: M Hausman M
AUTHOR: S Shacks S
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Immunologic alterations in patients with prostatic carcinoma.
PUBDATE: 19750601
The state of cell-mediated immunity was evaluated in 41 patients with prostatic carcinoma by determining their ability to demonstrate delayed cutaneous hypersensitivity with dinitrochlorobenzene and recall antigens, and to mount an inflammatory response to croton oil, as well as by measuring changes in monocyte chemotactic response. The patients were divided into 2 groups: those with localized disease and those with metastatic carcinoma. Monocyte chemotactic response provides an in vitro quantitative measure of effector cell function and was significantly depressed in the entire group of prostatic cancer patients as compared to non-cancer controls (p less than 0.05). Patients with metastatic carcinoma had a greater defect than those with localized disease (p less than 0.025). After radical prostatectomy a group of patients with localized disease tended to show improvement in monocyte chemotactic response (p less than 0.025). The ability of patients to develop a delayed cutaneous hypersensitivity response was impaired and correlated with the clinical stage of the disease. By using the cutaneous irritant, croton oil, the ability of these cancer patients to mount an inflammatory response was also found to be impaired and showed a close correlation between clinical stage and course of disease. Changes in response to croton oil tended to precede alterations in dinitrochlorobenzene response.

3. DOCID:10335 SCORE: 0.00325863255758671
DOCNO: 4057574
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: K Koiso K
AUTHOR: S Kanoh S
AUTHOR: T Yazaki T
AUTHOR: K Rinsho K
AUTHOR: R Nemoto R
AUTHOR: H Ishikawa H
AUTHOR: S Ishikawa S
AUTHOR: T Iizumi T
AUTHOR: K Uchida K
AUTHOR: R Noguchi R
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Present state of the multidisciplinary treatment of renal, bladder and prostatic tumors]
PUBDATE: 19850701
Surgery has been considered to be a main treatment of urogenital cancer. However, surgery alone could not completely cure these patients. The prognosis was poor. Multi-disciplinary treatment has been adopted to improve these results. However, there are many problems to be solved, such as combination of these regimens. In addition, the criteria for evaluation of the therapy should be considered. Nevertheless, multi-disciplinary treatment has been one of the most potent procedures for these malignancies.

4. DOCID:15592 SCORE: 0.00206766750061346
DOCNO: 2748158
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: adverse effects
QUALIFIER: drug therapy
QUALIFIER: chemically induced
AUTHOR: E Berényi E
AUTHOR: E Kiss E
PUBTYPE: Journal Article
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Management of vomiting induced by polychemotherapy in Hodgkin's disease]
PUBDATE: 19890601
Sixty patients with Hodgkin's disease were treated with a polychemotherapy regimen including very emetic dacarbazine and adriamycin in addition to bleomycin and vincristine on 622 treatment days during the last 10 years. Nausea in 97% and severe vomiting in 91% were observed during the treatment causing considerable distress to patients which led to patient noncompliance in 26.6%. Among the used antiemetic agents haloperidol was less active than high-dose metoclopramide alone or with high-dose methylprednisolone which were extremely effective. The control and prevention of drug-induced emesis is a major problem for cancer patients and their oncologists. The present situation and the home tasks are also discussed on the basis of literature and their observations.

5. DOCID:3247 SCORE: 0.00204481910826996
DOCNO: 1192362
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
QUALIFIER: genetics
AUTHOR: S Kakati S
AUTHOR: I Hayata I
AUTHOR: M Oshimura M
AUTHOR: A A Sandberg AA
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Chromosomes and causation of human cancer and leukemia. X. Banding patterns in cancerous effusions.
PUBDATE: 19751101
Cells from five cancer effusions (two ovarian carcinomas, two lung cancers, and one carcinoma of the breast) were analyzed by G-, C-, and Q-banding techniques. The following observations were made: 1) The origin of some marker chromosomes could be traced accurately by these banding techniques. 2) Several chromosomes, which appeared normal with conventional staining techniques, were found to be re-arranged ones and, hence, abnormal. 3) Chromosomes No. 1, No. 3 and No. 11 were the most frequently involved in aberrations, whereas No. 12, No. 13, No. 17-20, and No. 22 Were least frequently involved. Only in one case each was the X chromosome or the Y chromosome involved in aberrations. The Y chromosome was found to be missing in all cancer cells of one lung cancer. 4) Each effusion had characteristic markers, invariably present in each cell, whether the cells were near diploid, or polyploid. 5) No common markers were observed in the two ovarian carcinomas studied, whereas the two lung cancers had a few common markers.

6. DOCID:7339 SCORE: 0.00175836714533039
DOCNO: 665664
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: A B Miller AB
AUTHOR: A Kelly A
AUTHOR: N W Choi NW
AUTHOR: V Matthews V
AUTHOR: R W Morgan RW
AUTHOR: L Munan L
AUTHOR: J D Burch JD
AUTHOR: J Feather J
AUTHOR: G R Howe GR
AUTHOR: M Jain M
PUBTYPE: Journal Article
JOURNALTITLE: American journal of epidemiology.
COUNTRY: UNITED STATES
TITLE: A study of diet and breast cancer.
PUBDATE: 19780601
A case-control study has been conducted in four areas in Canada in which 40 cases of breast cancer matched by age and marital status with neighborhood controls were administered a medical and dietary history questionnaire, a 24-hour recall of dietary information and a four-day diet record. The Study has produced evidence of an association between an increased intake of nutrients, especially total fat, in both pre-menopausal and post-menopausal women with breast cancer. Reasons why a weak association might have been anticipated are discussed, and it is concluded that in reality the association is stronger. Furthermore, its consistency with other evidence, both experimental and international, suggests that it is causal.

7. DOCID:9542 SCORE: 0.0017497820579827
DOCNO: 3897621
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cryosurgery
DESCRIPTOR: Cystoscopes
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: Y Hikichi Y
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Cryoprostatectomy of prostatic tumors]
PUBDATE: 19850501
Since 1968, we have carried out cryoprostatectomy on prostatic hypertrophy and prostatic cancer patients. As for the method of monitoring during cryoprostatectomy, digital examination only was carried out at the beginning in order to confirm the range of freezing and to determine the freezing time. In 1972, we developed a cryoprostatectomy method under direct intravesicular observation using the Trocar Cystoscope and furthermore in 1980, we developed echoguided cryoprostatectomy using the transrectal linear electronic scanner. These new developments ensure the safety of cryoprostatectomy and furthermore, cryoprostatectomy can now be easily carried out. The above-mentioned procedures are described.

8. DOCID:10903 SCORE: 0.0017471280792614
DOCNO: 7114025
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J J Chuong JJ
AUTHOR: E M Livstone EM
AUTHOR: K W Barwick KW
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: UNITED STATES
TITLE: Systemic lupus erythematosus and gastric carcinoma: a report of two cases and a critical review of the literature.
PUBDATE: 19820901
Two cases of systemic lupus erythematosus in association with primary gastric adenocarcinoma are presented. A pathological analysis of the two cases of gastric cancer does not support the hypothesis that lupus and its associated vasculitis is involved in the pathogenesis of gastric carcinoma. A critical review of the literature reveals numerous case reports suggesting the association of systemic lupus erythematosus with various malignancies; however, there is no definitive study which substantiates the association of gastric or other cancers with lupus. Future studies will be required to assess appropriately the possibility of an association between lupus and cancer.

9. DOCID:2596 SCORE: 0.00174410322253891
DOCNO: 300279
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: A Saxon A
AUTHOR: J Portis J
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: Lymphoid subpopulation changes in regional lymph nodes in squamous head and neck cancer.
PUBDATE: 19770401
Lymph nodes from 10 normal patients and regional lymph nodes (RLN) from 19 patients with squamous cancer of the head and neck were evaluated as to their lymphoid subpopulations. In comparison to normal lymph nodes, RLN from cancer patients demonstrated a marked increase in the proportion of cells with membrane immunoglobulin, the receptor for the third component of complement, and the receptor for the Fc portion of immunoglobulin G. The increased Fc receptor cells were not Fc-bearing thymus-derived lymphocytes, inasmuch as they separated with the non-sheep erythrocyte-lymphocyte rosette-forming population. The overall thymus-derived lymphocyte percentage in RLN was proportionally decreased. A transition from the normal lymph node composition to the altered lymphocyte profile seen in RLN was demonstrated on moving from distal lymph nodes to RLN within the lymphatic drainage of a tumor. Lymph nodes involved with tumor also showed the pattern of bursa equivalent cell population increases.

10. DOCID:3585 SCORE: 0.00174400181795057
DOCNO: 200253
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: R A Hawkins RA
AUTHOR: A Hill A
AUTHOR: B Freedman B
AUTHOR: S M Gore SM
AUTHOR: M M Roberts MM
AUTHOR: A P Forrest AP
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Reproducibility of measurements of oestrogen-receptor concentration in breast cancer.
PUBDATE: 19770901
The reproducibility of measurements of oestrogen-receptor activity has been examined in multiple specimens from a rabbit uterus, a rat mammary tumour and human breast tumours. The relationship between receptor concentration and tumour histology has also been investigated in 11 large primary tumours. In the animal tissues, receptor measurements were relatively reproducible (coefficient of variance: wet wt. basis 16-17%, protein basis 16-21%) but in human breast tumours receptor activity varied considerably (c.v.: wet wt. basis, 22-125%; protein basis, 28-72%). In addition to these variations in receptor activity within tumours, there was a difference between tumours, as demonstrated by an analysis of variance (P less than 0.01). In the 11 primary breast cancers selected for study, the level of receptor activity was related to menopausal status and the tumour content of the specimen. We conclude that the receptor activity detected varies within a tumour and depends upon the tumour content of the biopsy specimen. Predictions based on precise quantitation of receptor concentrations may therefore necessitate replicate tumour sampling and correction for the fraction of non-tumour tissue in each sample.

11. DOCID:15731 SCORE: 0.00145908428603136
DOCNO: 3021068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: E Shimizu E
AUTHOR: K Kimura K
AUTHOR: S Sone S
AUTHOR: I Inoue I
AUTHOR: Y Nakamura Y
AUTHOR: Y Noda Y
AUTHOR: F Hojo F
AUTHOR: M Yagi M
AUTHOR: S Nakanishi S
AUTHOR: K Yamasaki K
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A phase II study of UFT in non-small cell lung cancer]
PUBDATE: 19861001
A phase II evaluation of UFT, a mixture of tegafur and uracil, was performed in 13 patients with non-small cell lung cancer (eight patients with adenocarcinoma and five patients with squamous cell carcinoma). UFT at a dose of 600 mg was given per os every day for more than four weeks. Among 12 evaluable patients, one patient with adenocarcinoma of the lung showed partial response. The response rate for UFT was 8.3%. Toxic effects included anorexia (31%), nausea (15%), liver disorder (15%), and pigmentation (8%).

12. DOCID:15757 SCORE: 0.00145908428457218
DOCNO: 3021068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: E Shimizu E
AUTHOR: K Kimura K
AUTHOR: S Sone S
AUTHOR: I Inoue I
AUTHOR: Y Nakamura Y
AUTHOR: Y Noda Y
AUTHOR: F Hojo F
AUTHOR: M Yagi M
AUTHOR: S Nakanishi S
AUTHOR: K Yamasaki K
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A phase II study of UFT in non-small cell lung cancer]
PUBDATE: 19861001
A phase II evaluation of UFT, a mixture of tegafur and uracil, was performed in 13 patients with non-small cell lung cancer (eight patients with adenocarcinoma and five patients with squamous cell carcinoma). UFT at a dose of 600 mg was given per os every day for more than four weeks. Among 12 evaluable patients, one patient with adenocarcinoma of the lung showed partial response. The response rate for UFT was 8.3%. Toxic effects included anorexia (31%), nausea (15%), liver disorder (15%), and pigmentation (8%).

13. DOCID:6937 SCORE: 0.00145762472388491
DOCNO: 6255626
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: A Gabler A
AUTHOR: S Liebig S
PUBTYPE: Journal Article
JOURNALTITLE: Thorax.
COUNTRY: ENGLAND
TITLE: Reoperation for bronchial carcinoma.
PUBDATE: 19800901
After a primary operation for bronchial carcinoma, 17 patients underwent reoperation for local recurrence or intrathoracic metastasis (nine squamous cell, five alveolar cell, and three adenocarcinomas). The average interval between the first and second operation was 23 months (range: six to 48 months). Twelve patients had a pneumonectomy after an initial ipsilateral lobectomy. Five patients underwent contralateral wedge excision after initial lobectomy or wedge excision. Three patients died within 30 days of the reoperation. Eight of the remaining 14 patients died subsequently, the time of survival averaging 18 months (range: three to 54 months). Six patients are still alive, two having survived their reoperation for more than five years. Reoperation for recurrent bronchial carcinoma is rarely performed, but it should be considered in all cases where patients survive operation for lung cancer if the primary operation was thought to be radical.

14. DOCID:11628 SCORE: 0.0014491325657341
DOCNO: 6629123
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: classification
AUTHOR: H Noguchi H
AUTHOR: K Shiozawa K
AUTHOR: T Tsukamoto T
AUTHOR: Y Tsukahara Y
AUTHOR: S Iwai S
AUTHOR: T Fukuta T
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: The postoperative classification for uterine cervical cancer and its clinical evaluation.
PUBDATE: 19831001
A postoperative classification for uterine cervical cancer has been made in consideration of the spatial spreading of cancer, biological malignancy of 120 cases which were treated with radical hysterectomy and pelvic lymphadnectomy. This classification corresponds extremely well to prognosis. The 5-year survival of the cases with prognostic index (P.I.) 9 or less was 96.1%, while those with P.I. above 10 showed 31.8%. In the Shinshu University School of Medicine clinic, this classification has become indispensable for decision of postoperative irradiation, selection of irradiation methods, and chemotherapeutic agents. Using this classification for individualized therapy, the survival rate was elevated in advanced cancer, class III or IV, with lymph node metastasis and P.I. above 10.