0. DOCID:17843 SCORE: 0.00117560343067312
DOCNO: 2200131
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: I C Henderson IC
AFFILIATION: Division of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: Basic principles in the use of adjuvant therapy.
PUBDATE: 19900801
Data from collaborative trials clearly indicate that the primary effect of adjuvant therapy is to delay death from breast cancer by months or years. However, adjuvant chemotherapy does not appear to prolong the survival of women aged 50 years or older, and tamoxifen has not yet been shown to improve the survival of women younger than age 50. In three trials involving node-negative patients, all showed a highly significant improvement in disease-free survival despite different chemotherapeutic regimens and durations of regimens.


1. DOCID:19167 SCORE: 0.00055837377590068
DOCNO: 1696521
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: P L Birnbaum PL
AUTHOR: C D Mercer CD
AFFILIATION: Department of Surgery, Hotel Dieu Hospital, Queen's University, Kingston, Ont.
PUBTYPE: Journal Article
JOURNALTITLE: Canadian journal of surgery. Journal canadien de chirurgie.
COUNTRY: CANADA
TITLE: Laser fulguration for palliation of rectal tumours.
PUBDATE: 19900801
Palliative therapy for rectal carcinoma includes control of bleeding, tenesmus, mucous discharge, obstruction and pain. These local symptoms can cause serious morbidity for patients with locally advanced or metastatic rectal cancer. As an alternative to surgical resection for palliation, the authors applied endoscopic laser fulguration in 15 patients with rectal tumours; 14 experienced immediate relief of symptoms. At 6.4 months' follow-up, two patients had recurrent tenesmus and two required a colostomy. A high degree of patient acceptance makes laser fulguration for rectal tumours an important modality, for palliation; however, control of tenesmus may be temporary.


2. DOCID:17552 SCORE: 0.0005568791811399
DOCNO: 1966466
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: secretion
AUTHOR: J C Aparicio Martínez JC
AUTHOR: F Marcos Sánchez F
AUTHOR: F Juárez Ucelay F
AUTHOR: P Llorente Domingo P
AUTHOR: A Durán Pérez-Navarro A
AFFILIATION: Servicio de Medicina Interna, Hospital del Insalud, Talavera de la Reina, Toledo.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Anales de medicina interna (Madrid, Spain : 1984)
COUNTRY: SPAIN
TITLE: [Erythematous reticular mucinosis associated with breast cancer]
PUBDATE: 19900201
A case of reticular erythematous mucinosis of histology and atypical localization in a patient with breast cancer, is presented. This patient had a history of benign tumors of muscular origin localized in uterus and stomach. We focus on the rareness of this syndrome and its association with other tumors, a point not shown in the literature.


3. DOCID:17557 SCORE: 0.000556872391809709
DOCNO: 2247530
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Sick Role
DESCRIPTOR: Social Adjustment
QUALIFIER: surgery
QUALIFIER: psychology
QUALIFIER: surgery
QUALIFIER: psychology
AUTHOR: B Schmidt B
AUTHOR: B Bauer B
AFFILIATION: Abteilung Neurologie, Universität Rostock.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Psychiatrie, Neurologie, und medizinische Psychologie.
COUNTRY: GERMANY
TITLE: [Psychosocial management of glioma patients treated with combined therapy]
PUBDATE: 19900801
Based on an empirical study it is pointed out that psychosocial care of patients with glioma differs in some points from that of other cancer patients. The first essential difference is that the emotional involvement of the care staff is not as intensive as those of other cancer patients. Other differences concern some illness- and therapy related effects such as family problems or monotony problems resulting from the longterm therapy. These specific problems are described in detail.


4. DOCID:18679 SCORE: 0.000556871965283925
DOCNO: 2344249
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: A Deschildre A
AUTHOR: L Vallee L
AUTHOR: M F Croquette MF
AUTHOR: B Nelken B
AUTHOR: J P Nuyts JP
AFFILIATION: Service des Maladies infectieuses et de Neurologie infantile, CHR Lille.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Archives françaises de pédiatrie.
COUNTRY: FRANCE
TITLE: [Oncologic complications and cytogenetic features of ataxia telangiectasia]
PUBDATE: 19900301
A very high incidence of cancers (10%) is recorded in patients homozygous for ataxia telangiectasia (AT). From 1970 to 1987, 35 children were investigated in the department of pediatric neurology in Lille. Three developed a malignancy (one hepatic tumor, one Hodgkin's disease and one non Hodgkin's lymphoma). Constitutional chromosome fragility and immune deficiency are the main features of AT. The first one is probably linked to the pathogenesis of malignancies. Moreover, cancer therapy has to take these features into account.


5. DOCID:19483 SCORE: 0.000556871075046315
DOCNO: 1325301
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: pathology
QUALIFIER: congenital
AUTHOR: R S Houlston RS
AUTHOR: T Fallon T
AUTHOR: C Harocopos C
AUTHOR: C B Williams CB
AUTHOR: C Davey C
AUTHOR: J Slack J
AFFILIATION: Department of Clinical Genetics, Royal Free Hospital and School of Medicine, London, UK.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical genetics.
COUNTRY: DENMARK
TITLE: Congenital hypertrophy of retinal pigment epithelium in patients with colonic polyps associated with cancer family syndrome.
PUBDATE: 19920701
Congenital hypertrophy of retinal pigment epithelium (CHRPE) has been shown to be a frequent extracolonic manifestation of adenomatous polyposis coli (APC). The presence of CHRPE in patients with adenomatous polyps from families with cancer family syndrome suggests possible involvement of the APC gene locus in syndromes associated with less florid polyp formation than seen in APC. It also emphasises that caution must be exercised in using the presence of CHRPE clinically as a marker for APC in isolated at-risk individuals.


6. DOCID:18782 SCORE: 0.000556870289436991
DOCNO: 1335475
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: history
AUTHOR: G M Palatianos GM
AUTHOR: J R Cintron JR
AUTHOR: T Narula T
AFFILIATION: University of Miami School of Medicine.
PUBTYPE: Biography
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of the Florida Medical Association.
COUNTRY: UNITED STATES
TITLE: George N. Papanicolaou, M.D. Father of modern cytology. A 30-year commemorative.
PUBDATE: 19921201
Thirty years have passed since the death of the renowned Dr. George N. Papanicolaou, a man of conviction and discoverer of the Pap smear. Despite difficulties and opposition he remained persistent and developed a method for early cancer detection. Subsequently, use of the Pap smear has resulted in a 70% decrease in cervical and uterine cancer deaths in the last 40 years. It is considered a reliable technique and is still expanding by being applied to other organs and systems and in the use of fine needle aspiration.


7. DOCID:19197 SCORE: 0.000556869375780216
DOCNO: 8341818
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J M Pedrajas JM
AUTHOR: J J Valverde JJ
AUTHOR: M J Téllez MJ
AUTHOR: A Castaño A
AUTHOR: R Pieltain R
AUTHOR: A Fernández-Cruz A
AFFILIATION: Servicio de Medicina Interna III, Hospital Universitario San Carlos, Madrid.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Revista clínica española.
COUNTRY: SPAIN
TITLE: [Epidermoid carcinoma of the pancreas associated with malignant humoral hypercalcemia]
PUBDATE: 19930601
Pure squamous carcinoma is a rare pancreas cancer histological variety. Moreover the association of malign humoral hypercalcemia and neoplasia of the pancreas exocrine portion is extremely rare. The case of a patient with pure squamous pancreas carcinoma and hypercalcemia is discussed. The absence of bone metastasis allowed to classify it within the malign humoral hypercalcemia syndrome. It is the first case described in the spanish scientific literature and the third in the international literature of an epidermoid pancreas carcinoma associated to malign humoral hypercalcemia.


8. DOCID:18943 SCORE: 0.000556868516293793
DOCNO: 1280474
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Radioimmunodetection
QUALIFIER: radionuclide imaging
AUTHOR: Q Zhou Q
AFFILIATION: PUMC Hospital, CAMS, Beijing.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences.
COUNTRY: ENGLAND
TITLE: Clinical application of radioimmunoimaging in the detection of tumors--current status in China.
PUBDATE: 19920601
In this article, the development of radioimmunoimaging (RII) in China is reviewed. Since 1984 conventional heterologous specific antibodies (Abs), such as anti-carcinoembryonic antigen (CEA) and anti-alphafetoprotein (AFP) Abs, have been used to detect cancers of the colon, ovary, lung, liver, etc. Later on, Abs against specific tumor cell-associated antigens have been produced in many institutions and applied clinically, with quite satisfactory results (detection rate ranging from 80-90%). Recently, human monoclonal antibodies (McAbs) are also being prepared. Finally, the existing problems to be overcome are discussed.


9. DOCID:17612 SCORE: 0.000556867943498778
DOCNO: 1833804
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: standards
AUTHOR: M Goodman M
AFFILIATION: Section of Medical Oncology, Rush Presbyterian St. Luke's Medical Center, Chicago, IL.
PUBTYPE: Journal Article
PUBTYPE: Meta-Analysis
JOURNALTITLE: Seminars in oncology nursing.
COUNTRY: UNITED STATES
TITLE: Adjuvant systemic therapy of stage I and II breast cancer.
PUBDATE: 19910801
The value of adjuvant systemic therapy has been clearly demonstrated in both node-positive and node-negative patients. However, there are many women with favorable prognoses whose breast cancer recurs. It has been possible only recently to identify subsets of patients who are at definite risk for recurrence. Advances both in selection and treatment of patients with early-stage breast cancer are being made as critical research questions are delineated and examined in prospective randomized trials.


10. DOCID:18094 SCORE: 0.000556867187526917
DOCNO: 2393303
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: K Sekiba K
AUTHOR: R Hayase R
AFFILIATION: Dept. of Obstetrics and Gynecology, Okayama University Medical School.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Therapy of recurrent cervical cancer]
PUBDATE: 19900901
1,122 uterine cancer patients above FIGO stage I a were treated at our hospital in the decade from 1980 to 1989. Total 69 patients diagnosed as recurrent cervical cancer had 82 lesions in 11 sites. The most frequent recurrent sites were uterus, vaginal stump and vaginal wall; the second sites were parametrium and pelvic wall. Radiotherapy and hyperthermia were done to patients with these lesions. Chemotherapy and radiotherapy were used to patients with distant metastatic lesions to left supraclavicular lymph nodes and lung. But there has been no good results.


11. DOCID:18176 SCORE: 0.00055686660786393
DOCNO: 8100442
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Drug Resistance
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: pathology
AUTHOR: A Katagiri A
AUTHOR: Y Tomita Y
AUTHOR: T Nishiyama T
AUTHOR: M Kimura M
AUTHOR: S Sato S
AFFILIATION: Department of Urology, Niigata University School of Medicine, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Immunohistochemical detection of P-glycoprotein and GSTP1-1 in testis cancer.
PUBDATE: 19930701
P-glycoprotein (Pgp) and pi-class glutathione S-transferase (GSTP1-1) are thought to be correlated with multiple drug resistance. In immunohistochemical staining, non-seminomatous germ cell tumours, which are more refractory than seminomas to anti-cancer chemotherapy, frequently expressed Pgp and GSTP1-1. Western blot analysis demonstrated lower amount of GSTP1-1 in seminoma than in teratoma. These results suggest that Pgp and GSTP1-1 might contribute to drug resistance in testis cancers.


12. DOCID:17220 SCORE: 0.000556866303507605
DOCNO: 8490878
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Adaptation, Psychological
DESCRIPTOR: Family
QUALIFIER: psychology
AUTHOR: M J Kupst MJ
AFFILIATION: Medical College of Wisconsin, Milwaukee 53226.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Family coping. Supportive and obstructive factors.
PUBDATE: 19930501
Successful coping with pediatric cancer enables the family to participate in the effective care of the child. This article focuses on those family variables associated with coping and adjustment to pediatric cancer. Among the variables most commonly noted as risk factors are the following: low socioeconomic status, concurrent stresses, low level of support, pre-existing serious psychologic problems in a family member, and inadequate coping resources. Implications of these risk factors for poor coping are discussed as well as recommendations for further investigation.


13. DOCID:18829 SCORE: 0.000556865685544849
DOCNO: 2201913
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mutagens
DESCRIPTOR: Secologanin Tryptamine Alkaloids
QUALIFIER: drug effects
QUALIFIER: toxicity
QUALIFIER: analogs & derivatives
AUTHOR: G von Poser G
AUTHOR: H H Andrade HH
AUTHOR: K V da Silva KV
AUTHOR: A T Henriques AT
AUTHOR: J A Henriques JA
AFFILIATION: Curso de Pós-Graduação em Farmácia, Faculdade de Farmácia, UFRGS, Porto Alegre, RS, Brazil.
PUBTYPE: Journal Article
JOURNALTITLE: Mutation research.
COUNTRY: NETHERLANDS
TITLE: Genotoxic, mutagenic and recombinogenic effects of rauwolfia alkaloids.
PUBDATE: 19900901
In the last decade, the possible correlation between the use of reserpine and rauwolfia drugs as antihypertensive agents and breast cancer incidence has been investigated. For the purpose of evaluating the mutagenic and genotoxic effects of these drugs, reserpine and ajmalicine were studied using the SOS Chromotest and the induction of gene conversion, crossing-over and reverse mutation in the yeast diploid strain XS2316. The results indicated a lack of genotoxic, mutagenic and recombinogenic effects.


14. DOCID:16491 SCORE: 0.000556865467192852
DOCNO: 1758641
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: C Avogadri C
AUTHOR: D Fisogni D
AUTHOR: A Braga A
AUTHOR: A Omodei A
AUTHOR: L Giambuzzi L
AUTHOR: C Dall'Olio C
AFFILIATION: Divisione di Chirurgia, Ospedale Civile, Chiari, BS.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Minerva chirurgica.
COUNTRY: ITALY
TITLE: [Efferent loop syndrome in gastric stump carcinoma. A clinical case]
PUBDATE: 19910901
The Authors describe a case of efferent loop syndrome in a patient with inoperable gastric stump cancer. The resolution of the symptomatology by an anastomosis between afferent and efferent loop in a tract without neoplastic infiltration, permitted a six month good life period to the patient.