0. DOCID:26215 SCORE: 0.00514991682752684
DOCNO: 11057313
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: N Horikoshi N
AUTHOR: T Saotome T
AUTHOR: N Yoshida N
AUTHOR: K Aiba K
AFFILIATION: Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Oral cancer chemotherapy in the clinic]
PUBDATE: 20001001
The present status of oral chemotherapeutic agents and the treatment of cancer were reviewed. Twenty anticancer agents are commercially available in Japan excluding hormonal and BRM agents. Cancers for the outpatient chemotherapy are limited because useful drugs are few for such circumstances. Now new potent agents such as S-1, capecitabine and molecular targeting are available. This kind of chemotherapy is needed for growing number of elderly patients for QOL and medical cost.


1. DOCID:25393 SCORE: 0.00414605111602467
DOCNO: 11253600
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: pathology
QUALIFIER: therapy
AUTHOR: O Choy O
AUTHOR: T Jahan T
AUTHOR: M Roach M
AUTHOR: L You L
AUTHOR: D Jablons D
AFFILIATION: Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest surgery clinics of North America.
COUNTRY: United States
TITLE: Stage II (N1) lung cancer.
PUBDATE: 20010201
As therapies evolve and mature, the authors predict that the next 20 years will see significant advances in the understanding of non-small-cell lung cancer (NSCLC), in molecular stratification of NSCLC, and significant improvement in survival and cure rates. This survival will be achieved through early detection and combined treatments using effective surgical interventions, improved radiotherapeutics, and especially significantly enhanced, rationally designed systemic therapies.


2. DOCID:26211 SCORE: 0.00401377504492008
DOCNO: 11189691
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
DESCRIPTOR: Randomized Controlled Trials
DESCRIPTOR: Survival Analysis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: A B Miller AB
AUTHOR: S Yurgalevitch S
AUTHOR: J L Weissfeld JL
AFFILIATION: Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
PUBTYPE: Journal Article
JOURNALTITLE: Controlled clinical trials.
COUNTRY: United States
TITLE: Death review process in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
PUBDATE: 20001201
The procedures that have been adopted in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial are described. These procedures have been designed to ensure unbiased decisions on the underlying cause of death for all confirmed or suspected PLCO cancers. A death review committee with a nonvoting chair and three experienced reviewers as members has been appointed. After an initial pilot study, the procedures have been instituted and are working well.


3. DOCID:25389 SCORE: 0.00378576817348553
DOCNO: 11431932
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: Y Kaji Y
AUTHOR: K Sugimura K
AFFILIATION: Department of Radiology, Kobe University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica.
COUNTRY: Japan
TITLE: [Diagnostic imaging in male pelvic disorders]
PUBDATE: 20010501
This article reviews the imaging findings of male pelvic disorders, especially those of prostate disease. Magnetic resonance imaging (MRI) provides excellent anatomical detail, and is useful to stage prostate cancer and to understand the process of anomaly. However, failure to detect capsular invasion remains a significant weakness in prostate cancer. It is important to understand the limits and contributions of MRI to the staging of prostate cancer, and to perform the appropriate examination.


4. DOCID:26651 SCORE: 0.00374314652711653
DOCNO: 11307061
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: M Lingen M
AUTHOR: E M Sturgis EM
AUTHOR: M S Kies MS
AFFILIATION: Loyola University Medical Center, Department of Pathology & The Cardinal Bernardin Cancer Center, Maywood, Illinois, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: United States
TITLE: Squamous cell carcinoma of the head and neck in nonsmokers: clinical and biologic characteristics and implications for management.
PUBDATE: 20010501
Squamous cell carcinoma of the head and neck has been strongly linked to chronic tobacco and alcohol abuse. However, we are increasingly recognizing subgroups of patients without traditional risk factors. Recent clinical and molecular investigations suggest that there are distinctive clinical entities, particularly affecting young patients with cancers of the oral tongue and oropharynx. We review data from clinical observations and current biologic inquiries and consider therapeutic implications for these important patient subgroups.


5. DOCID:27228 SCORE: 0.00370455154287948
DOCNO: 10884619
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bifidobacterium
DESCRIPTOR: Lactobacillus
QUALIFIER: prevention & control
QUALIFIER: therapeutic use
AUTHOR: K Hirayama K
AUTHOR: J Rafter J
AFFILIATION: Department of Medical Nutrition, Karolinska Institute, NOVUM, S-141 86, Huddinge, Sweden.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Microbes and infection / Institut Pasteur.
COUNTRY: FRANCE
TITLE: The role of probiotic bacteria in cancer prevention.
PUBDATE: 20000501
Colorectal cancer is one of the most important causes of cancer morbidity and mortality in western countries [1]. A myriad of healthful effects have been attributed to the probiotic lactic acid bacteria; perhaps the most controversial remains that of anticancer activity. There is no direct experimental evidence for cancer suppression in humans as a result of consumption of lactic cultures in fermented or unfermented dairy products. However, there is a wealth of indirect evidence, based largely on laboratory studies, in the literature and this will be summarised in the present paper.


6. DOCID:27154 SCORE: 0.00370442152787319
DOCNO: 11000056
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathogenicity
QUALIFIER: etiology
QUALIFIER: metabolism
AUTHOR: M W White MW
AFFILIATION: cancer.conquest@att.net
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Medical hypotheses.
COUNTRY: SCOTLAND
TITLE: Cancer: the role of oxygen in fungal-induced carcinogenesis.
PUBDATE: 20001001
The mammalian cancer cell demonstrates that this animal cell respires and metabolizes anaerobically. It not only maintains a strong viability but can enlarge as a tumor, to spread circumferentially, to the lymph nodes and distal areas.Our studies with supportive and tantalizing evidence indicate that cancer is due to the intracellular presence of an invasive obligate asexual anaerobe microorganism. Genetically, this anaerobe possesses a (nonmetal) electronegative element compound. This element compound is one that has the affinity to accept and add electrons in a chemical reaction. The presence of this obligate anaerobe with its specific chemistry, along with the host's circulating flow of blood, are the critical cofactors in carcinogenesis.


7. DOCID:27973 SCORE: 0.00365363452078692
DOCNO: 11715303
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: G Calais G
AUTHOR: E Asquier E
AUTHOR: P Louisot P
AFFILIATION: Clinique d'oncologie et radiothérapie, CHU, 2, boulevard Tonnellé, 37044 Tours, France. calais@med.univ-tours.fr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer radiothérapie : journal de la Société française de radiothérapie oncologique.
COUNTRY: France
TITLE: [Gross tumor volume and clinical target volume: esophageal tumors]
PUBDATE: 20011001
The oesophagus is divided into four regions: cervical oesophagus, and intrathoracic oesophagus with an upper, mid- and lower thoracic portion. Cancer may occur on each of these regions. Computed tomography of the thorax and superior abdomen and endoscopic ultrasound are necessary for reliable staging. CT simulation allows accurate definition of tumour volume. GTV includes tumour volume and regional lymph nodes. CTV encompasses GTV plus a safety margin and lymph node areas considered to harbour potential microscopic disease. The extent of prophylactic lymph node irradiation depends on the anatomic location of the primary tumour.


8. DOCID:26999 SCORE: 0.00363270378970399
DOCNO: 10410154
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Protein Biosynthesis
QUALIFIER: complications
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: H Koshida H
AUTHOR: T Kametani T
AUTHOR: S Masuda S
AFFILIATION: Second Dept. of Internal Medicine, Kohseiren Takaoka Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]
PUBDATE: 19990501
A 46-year-old man was diagnosed as Stage IV lung cancer with neck lymph node and bilateral adrenal metastases. He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure. The bisphosphonate, pamidronate with elcatonin and prednisolone dramatically lowered his serum calcium level and normalized his renal function. This is a representative case of humoral hypercalcemia of malignancy whose serum calcium could be safely and effectively controlled with pamidronate.


9. DOCID:26966 SCORE: 0.00363269245245838
DOCNO: 9973944
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosomes, Human, Pair 3
DESCRIPTOR: Translocation, Genetic
QUALIFIER: genetics
AUTHOR: J R Batanian JR
AUTHOR: C H Dunphy CH
AUTHOR: D A Wall DA
AFFILIATION: Department of Pediatrics, St. Louis University School of Medicine, MO 63104, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Jumping translocations of 3q in acute promyelocytic leukemia.
PUBDATE: 19990101
Jumping translocation is a rare phenomenon, seldom reported to occur in cancer. A complex four-way translocation involving chromosomes 3, 9, 15, and 17 was identified in the chromosome study on a patient with a history of an acute promyelocytic leukemia (APL). In the follow-up studies, the same complex rearrangement exhibited a jumping translocation between chromosomes 3 and 9 in one clone and 3 and 6 in another clone. This is the first reported case of jumping translocation in APL.


10. DOCID:26474 SCORE: 0.0036124280133619
DOCNO: 11317266
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: microbiology
QUALIFIER: microbiology
QUALIFIER: complications
QUALIFIER: drug effects
AUTHOR: C K Murray CK
AUTHOR: E A Walter EA
AUTHOR: S Crawford S
AUTHOR: M L McElmeel ML
AUTHOR: J H Jorgensen JH
AFFILIATION: Department of Medicine, Infectious Diseases Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234-6200, USA. Clinton.Murray@CEN.AMEDD.ARMY.MIL
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
COUNTRY: United States
TITLE: Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates.
PUBDATE: 20010501
We report a case of bacteremia due to Abiotrophia species in a patient with neutropenic fever and cancer who was receiving levofloxacin prophylaxis, followed by empirical therapy with cefepime; the organism was resistant to both antibiotics. We provide susceptibility data on 20 additional bloodstream isolates of Abiotrophia species.


11. DOCID:25728 SCORE: 0.00350370299432342
DOCNO: 11593143
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Colorectal Neoplasms, Hereditary Nonpolyposis
QUALIFIER: diagnosis
QUALIFIER: genetics
AUTHOR: B Dieumegard B
AFFILIATION: Service d'Hépato-Gastro-Entérologie, Hôpital Cochin, 24, rue du Faubourg-Saint-Jacques, 75014 Paris, France.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Annales de médecine interne.
COUNTRY: France
TITLE: [Hereditary non polyposis colorectal cancer]
PUBDATE: 20010901
Hereditary non polyposis colorectal cancer (HNPCC) is characterized by an excess of early colorectal carcinomas, preferentially located on the ascending colon, associated with a variety of extracolonic cancers. The recent demonstration of germline mutations in DNA mismatch repair genes in HNPCC patients enhanced the interest due to the syndrome. Molecular genetic testing of HNPCC has become available, and should help physicians to recommend specific modalities for the surveillance and the management of patients with such a high cancer risk.


12. DOCID:27790 SCORE: 0.00340942282895029
DOCNO: 11998038
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: prevention & control
AUTHOR: S C Grumet SC
AUTHOR: D W Bruner DW
AFFILIATION: Englewood-Mount Sinai Cancer Risk Assessment and Counselling Program, Mount Sinai School of Medicine/Englewood Hospital and Medical Center, Englewood, NJ, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Urologic nursing : official journal of the American Urological Association Allied.
COUNTRY: United States
TITLE: The identification and screening of men at high risk for developing prostate cancer.
PUBDATE: 20000201
It is estimated that the lifetime risk of being diagnosed with prostate cancer is 1 in 5. The identification of risk factors, including age, African-American ancestry, family history, and possibly diet and environmental factors, has allowed health care professionals the opportunity to identify, screen, and study men at the greatest risk of developing prostate cancer. The risk factors, current screening tools, and the informed consent process for men participating in a prostate cancer screening program are outlined.


13. DOCID:26489 SCORE: 0.00333178403656174
DOCNO: 10975688
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: complications
QUALIFIER: psychology
QUALIFIER: therapeutic use
AUTHOR: J Homsi J
AUTHOR: D Walsh D
AUTHOR: K A Nelson KA
AFFILIATION: A World Health Organization Demonstration Project, The Harry R. Horvitz Center for Palliative Medicine, Cleveland, Ohio, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
COUNTRY: GERMANY
TITLE: Psychostimulants in supportive care.
PUBDATE: 20000901
Psychostimulant medications have been used clinically and investigated in psychiatric populations, the medically ill, cancer patients and healthy people. This article discusses the pharmacology of dextroamphetamine, methylphenidate, pemoline (and other psychostimulants such as caffeine and ephedrine), their use in general medicine and cancer care, side effects, and abuse potential. Therapeutic use in children is addressed only insofar as it illustrates facets of their use in adults.


14. DOCID:26060 SCORE: 0.00319910451053498
DOCNO: 10879044
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Polymorphism, Single Nucleotide
QUALIFIER: genetics
QUALIFIER: methods
AUTHOR: I Mikami I
AUTHOR: H Nagai H
AUTHOR: H Harada H
AUTHOR: M Emi M
AFFILIATION: Department of Molecular Biology, Nippon Medical School.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Methods of single-nucleotide polymorphism analysis and application to hereditary cancer syndrome]
PUBDATE: 20000601
Single-nucleotide polymorphism analysis is important in all areas of molecular biology. The causative genes of hereditary cancer syndrome have been isolated. Recently, molecular diagnosis of hereditary cancer syndrome has been performed using methods of single-nucleotide polymorphism analysis and the usefulness has been reported. It is considered that progression of molecular biology will be able to contribute to diagnosis (especially pre-symptomatic diagnosis), prevention and treatment of hereditary cancer syndrome in the future.