0. DOCID:19930 SCORE: 0.00442590954186466
DOCNO: 2305043
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Statistical
QUALIFIER: epidemiology
QUALIFIER: adverse effects
QUALIFIER: epidemiology
AUTHOR: S A Feig SA
AUTHOR: S M Ehrlich SM
AFFILIATION: Department of Radiology, Jefferson Medical College and Thomas Jefferson University Hospital, Philadelphia, PA 19107.
PUBTYPE: Journal Article
JOURNALTITLE: Radiology.
COUNTRY: UNITED STATES
TITLE: Estimation of radiation risk from screening mammography: recent trends and comparison with expected benefits.
PUBDATE: 19900301
On the basis of recent epidemiologic studies, the National Institutes of Health in 1985 provided a new estimate for radiation risk to the breast that employed a relative risk model and acknowledged greater dependence on age at exposure. Lifetime risks from a single mammogram may be calculated from this estimate and are lower than those based on the previous 1977 National Cancer Institute estimate. Possible years of life expectancy lost from annual mammography beginning at age 40 years may also be calculated and are negligible compared with estimates for years of life expectancy gained from such screening.

1. DOCID:18521 SCORE: 0.00441562281213178
DOCNO: 2084339
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: therapeutic use
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: drug therapy
AUTHOR: E V Gembitskiĭ EV
AUTHOR: A S Portnoĭ AS
AUTHOR: A V Begunov AV
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia meditsina.
COUNTRY: USSR
TITLE: [Diagnosis and therapeutic correction of changes in the cardiovascular system of patients with prostatic cancer treated with estrogens]
PUBDATE: 19901201
Estrogen-related cardiovascular dysfunction was noted in 23 out of 30 patients with prostatic cancer (PC). Coronary subjects with PC suffered from cardiac pain evident on ECG necessitating correction by effective doses of coronary active drugs. PC patients with essential hypertension exhibited frequent headache, progressive edema of the legs, drastic hypertensive reactions. It is held that estrogen therapy for prostatic cancer should be preceded and monitored by therapeutic evaluation responsible for optimal conditions to prevent and early diagnose cardiovascular complications.

2. DOCID:19291 SCORE: 0.00436241714472716
DOCNO: 8393415
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Virus Cultivation
QUALIFIER: growth & development
AUTHOR: O Faff O
AUTHOR: B A Murray BA
AUTHOR: V Erfle V
AUTHOR: R Hehlmann R
AFFILIATION: Medizinische Poliklinik, Universität München, FRG.
PUBTYPE: Journal Article
JOURNALTITLE: FEMS microbiology letters.
COUNTRY: NETHERLANDS
TITLE: Large scale production and purification of human retrovirus-like particles related to the mouse mammary tumor virus.
PUBDATE: 19930501
Human retrovirus-like particles related to mouse mammary tumor virus (MMTV) are secreted in a steroid-dependent manner by the breast cancer cell line T47D. We report the successful large scale production and purification of these particles from culture supernatants of T47D cells and describe the experimental conditions established for this purpose. Thus, mg amounts of particles were produced by large scale culturing of T47D cells in an autoharvesting roller bottle system and purified by differential centrifugation and continuous flow ultracentrifugation on density gradients with a 50% recovery and a 350-fold enrichment.

3. DOCID:17955 SCORE: 0.00375013649632517
DOCNO: 2233589
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Aging
DESCRIPTOR: Sex Factors
QUALIFIER: mortality
AUTHOR: B Böhm B
AUTHOR: K Nouchirvani K
AUTHOR: H P Hucke HP
AUTHOR: W Stock W
AFFILIATION: Chirurgische Abteilung, Marien-Hospitals Düsseldorf.
PUBTYPE: Journal Article
JOURNALTITLE: Medizinische Klinik (Munich, Germany : 1983)
COUNTRY: GERMANY
TITLE: [The effect of age and sex on localization, tumor stage and prognosis of colorectal carcinoma]
PUBDATE: 19901001
In a retrospective study including 946 cases with colorectal cancer we analysed age, sex, distribution and stage. There was a significant higher prevalence in women and in all tumor stages women were older than men. The frequencies of Dukes C and proximal colon cancer was significantly higher in women. In older patients we found an increasing incidence of proximal cancer. Instead of tumor stage the age, sex and distribution showed no influence on the outcome.

4. DOCID:19305 SCORE: 0.00374255884961038
DOCNO: 1405166
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: Y Fujii Y
AUTHOR: J Ajima J
AUTHOR: A Tosaka A
AUTHOR: H Sekine H
AUTHOR: K Ohya K
AUTHOR: S Kitahara S
AUTHOR: H Ohashi H
AUTHOR: K Oka K
AFFILIATION: Division of Urology, Kanto Central Hospital.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Hinyōkika Gakkai zasshi. The japanese journal of urology.
COUNTRY: JAPAN
TITLE: [Asymptomatic multilocular cystic renal cell carcinoma]
PUBDATE: 19920801
From January 1982 to December 1989, we experienced seven multilocular cystic renal cell carcinomas (MLCRCCs) in 36 asymptomatic renal cancers incidentally diagnosed, and none in 23 symptomatic renal cancers (p less than 0.05). No multiocular cystic nephromas (MLCNs) appeared in either group. Though MLCRCCs have been considered to be, in general, extremely rare, they do occur in asymptomatic renal cancers. A multiloculated renal mass with thick septum discovered in an adult by ultrasonography or CT scan should be suspected as being a MLCRCC rather than a MLCN.

5. DOCID:19160 SCORE: 0.00370626892981316
DOCNO: 2217209
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Carcinogens
DESCRIPTOR: Mice
DESCRIPTOR: Rats
QUALIFIER: methods
AUTHOR: B N Ames BN
AUTHOR: L S Gold LS
AFFILIATION: Division of Biochemistry and Molecular Biology, University of California, Berkeley 94720.
PUBTYPE: Journal Article
JOURNALTITLE: Proceedings of the National Academy of Sciences of the United States of America.
COUNTRY: UNITED STATES
TITLE: Chemical carcinogenesis: too many rodent carcinogens.
PUBDATE: 19901001
The administration of chemicals at the maximum tolerated dose (MTD) in standard animal cancer tests is postulated to increase cell division (mitogenesis), which in turn increases rates of mutagenesis and thus carcinogenesis. The animal data are consistent with this mechanism, because a high proportion--about half--of all chemicals tested (whether natural or synthetic) are indeed rodent carcinogens. We conclude that at the low doses of most human exposures, where cell killing does not occur, the hazards to humans of rodent carcinogens may be much lower than is commonly assumed.

6. DOCID:18815 SCORE: 0.00369066511097617
DOCNO: 2044776
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: instrumentation
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: V Barreto V
AUTHOR: H Hamed H
AUTHOR: A B Griffiths AB
AUTHOR: A Hanby A
AUTHOR: M A Chaudary MA
AUTHOR: I S Fentiman IS
AFFILIATION: ICRF Clinical Oncology Unit, Guy's Hospital, London.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Automatic needle biopsy in the diagnosis of early breast cancer.
PUBDATE: 19910601
An automatic needle biopsy system, Bioptycut, has been evaluated for use in the outpatient biopsy of 107 patients with suspected operable breast cancer. Of the 107 patients, 96 proved to have malignancy. The sensitivity of the test was 65%, and the specificity 100%. Using a fine gauge needle the sensitivity was originally less than that of Trucut biopsy, but improved results were obtained with more experience.

7. DOCID:18408 SCORE: 0.00366868200635969
DOCNO: 1449976
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: E J Weinman EJ
AUTHOR: R V Patak RV
AFFILIATION: UCLA-San Fernando Valley Program, Department of Veterans Affairs Medical Center, Sepulveda.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Acute renal failure in cancer patients.
PUBDATE: 19920901
Compromise of kidney function in patients with serious medical illnesses, including cancer, is a serious and potentially fatal complication. In cancer patients, the types of renal injury that may occur are more varied than in patients with other underlying illnesses, and definition of the etiology of the decline in renal function may have important therapeutic and prognostic implications. This review article discusses the clinical manifestations and the diagnostic workup of insults to the kidney in patients with cancer. Therapy (excluding dialysis) for each type of renal insufficiency is briefly reviewed.

8. DOCID:19112 SCORE: 0.00347762839210305
DOCNO: 1452514
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: P J Rosen PJ
AFFILIATION: Division of Hematology/Oncology, University of California, School of Medicine, Los Angeles.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: ENGLAND
TITLE: Bleeding problems in the cancer patient.
PUBDATE: 19921201
Bleeding problems in the cancer patient may result from the effects of the tumor on hemostatic mechanisms or from the treatment of the tumor by cytotoxic and other agents. Among the tumor-related bleeding problems are disseminated intravascular coagulation, primary fibrinolysis, thrombocytopenia, acquired platelet dysfunction, and circulating inhibitors or anticoagulants. Disseminated intravascular coagulation in most solid tumors is associated with hypercoagulability, whereas in acute promyelocytic leukemia bleeding is the most common presentation. Treatment-related bleeding disorders include the common problem of thrombocytopenia secondary to myelosuppressive chemotherapy as well as the interesting microangiopathic hemolytic anemia syndrome associated with mitomycin C and other agents.

9. DOCID:19148 SCORE: 0.00346146210286059
DOCNO: 2053776
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: administration & dosage
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: M Furutani M
AUTHOR: Y Shimada Y
AUTHOR: K Inoue K
AUTHOR: T Tobe T
AFFILIATION: First Dept. of Surgery, Faculty of Medicine, Kyoto University.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case report of liver metastasis from rectal cancer effectively treated with intravenous infusion of cisplatin alone]
PUBDATE: 19910601
A 49-year-old man with liver metastasis from rectal cancer was treated with cisplatin (CDDP) alone. Cisplatin was administered intravenously 3 times at a dose of 50 mg (31 mg/m2). He achieved an excellent PR (94% decrease) as determined by CT scanning, and plasma CEA level decreased from 37 to 2.2 ng/ml. The side effects were nausea, vomiting, and reflux esophagitis, but neither leucopenia nor renal dysfunction was observed. As a result, a radical operation could be undertaken.

10. DOCID:18741 SCORE: 0.00340990716179277
DOCNO: 1862534
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: drug effects
AUTHOR: G Powis G
AFFILIATION: Department of Pharmacology, Mayo Clinic and Foundation, Rochester, MN 55905.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Trends in pharmacological sciences.
COUNTRY: ENGLAND
TITLE: Signalling targets for anticancer drug development.
PUBDATE: 19910501
Intracellular signalling pathways mediating the effects of growth factors and oncogenes on cell growth and transformation present a challenging new class of target sites for anticancer drug development. Several drugs are already available that may act in this way, including drugs that act on protein serine/threonine kinases, protein tyrosine kinases and phospholipase C, as well as inhibitors of myo-inositol signalling. As our understanding of the signalling pathways involved in growth control increases, new sites for pharmacological intervention will become apparent. Garth Powis reviews the evidence that this approach may eventually lead to new, more selective drugs for treating cancer.

11. DOCID:17921 SCORE: 0.00340665982319645
DOCNO: 8236611
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: N N Stone NN
AUTHOR: R N Schlussel RN
AUTHOR: R L Waterhouse RL
AUTHOR: P Unger P
AFFILIATION: Department of Urology, Mount Sinai Medical Center, New York, New York.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: Laparoscopic retroperitoneal lymph node dissection in stage A nonseminomatous testis cancer.
PUBDATE: 19931101
Open retroperitoneal lymph node dissection in clinical Stage A testis cancer offers the advantages of definitive staging and high cure rates. Observation is elected in various settings to avoid the morbidity and possible sequelae of this procedure. We present a case report of a new procedure, laparoscopic retroperitoneal lymph node dissection, that decreases hospital stay, recovery time, and morbidity while maintaining the advantages of open retroperitoneal lymph node dissection.

12. DOCID:18443 SCORE: 0.00339900707082418
DOCNO: 1995364
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: J S Sham JS
AUTHOR: D Choy D
AFFILIATION: Department of Radiotherapy and Oncology, Queen Mary Hospital, Hong Kong.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Breast metastasis from nasopharyngeal carcinoma.
PUBDATE: 19910201
The first two cases of breast metastases from anaplastic carcinoma of the nasopharynx are presented. In both cases the breast metastasis was solitary, but there was no delay in confirming their metastatic nature since both lesions manifested after the documentation of disseminated disease. The difference in histology, since 99% of our nasopharyngeal carcinoma patients have anaplastic carcinoma of poorly differentiated carcinoma subtype, makes it easy to differentiate them from primary breast cancer by cytology or histology.

13. DOCID:18968 SCORE: 0.00331199223946535
DOCNO: 1831642
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: A K Choucair AK
AFFILIATION: Dept. of Neurology, Marshfield Clinic, Wisconsin.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Myelopathies in the cancer patient: incidence, presentation, diagnosis and management. Part 1.
PUBDATE: 19910601
Neurological involvement with systemic cancer is frequently a cause of major disability. Second to brain metastases, metastasis to the spinal cord and its nerve roots constitutes the most common neurological complication of cancer with an estimated 5 to 10% of patients developing spinal cord involvement that leads to serious impairment of function. With advances in cancer therapy and consequent extension of survival, the overall incidence of neurological complications of cancer is on the rise. Spinal cord dysfunction, while usually nonfatal, leaves the patient with a major neurological disability. The author discusses epidural metastases, highlighting the importance of early recognition and management.

14. DOCID:19274 SCORE: 0.00330522364672927
DOCNO: 2319828
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: P G Shields PG
AUTHOR: C C Harris CC
AFFILIATION: Division of Cancer Etiology, National Cancer Institute, Bethesda, Maryland.
PUBTYPE: Journal Article
JOURNALTITLE: The Medical clinics of North America.
COUNTRY: UNITED STATES
TITLE: Environmental causes of cancer.
PUBDATE: 19900301
The development of cancer in an individual is the result of multiple genetic and epigenetic steps. Carcinogens and tumor promoters can act by a variety of molecular mechanisms, and repeated exposure to numerous agents is frequently necessary for the formation of cancer. The estimate of cancer risk in a population is performed via a formal quantitative risk assessment. The estimated risk in an individual is more complex because of both inherited predispositions and lifestyle. Although information is available, it is essential to understand the goals, attributes, and limitations of the experimental methods underlying our current understanding of the environmental causes of cancer.