0. DOCID:26215 SCORE: 0.00514991682752684
DOCNO: 11057313
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: N Horikoshi N
AUTHOR: T Saotome T
AUTHOR: N Yoshida N
AUTHOR: K Aiba K
AFFILIATION: Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Oral cancer chemotherapy in the clinic]
PUBDATE: 20001001
The present status of oral chemotherapeutic agents and the treatment of cancer were reviewed. Twenty anticancer agents are commercially available in Japan excluding hormonal and BRM agents. Cancers for the outpatient chemotherapy are limited because useful drugs are few for such circumstances. Now new potent agents such as S-1, capecitabine and molecular targeting are available. This kind of chemotherapy is needed for growing number of elderly patients for QOL and medical cost.


1. DOCID:23258 SCORE: 0.00489581994529001
DOCNO: 7497468
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: isolation & purification
QUALIFIER: analogs & derivatives
QUALIFIER: chemistry
AUTHOR: D Nakae D
AUTHOR: Y Mizumoto Y
AUTHOR: E Kobayashi E
AUTHOR: O Noguchi O
AUTHOR: Y Konishi Y
AFFILIATION: Department of Oncological Pathology, Nara Medical University, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer letters.
COUNTRY: IRELAND
TITLE: Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue.
PUBDATE: 19951101
Using two different commercially available extraction kits, genomic/nuclear DNA could be recovered from rat liver samples as small as 10 mg. Background 8-hydroxydeoxyguanosine levels in such DNA were low and stable at 0.26-0.30 +/- 0.01-0.03/10(5) guanine residues. The minimum tissue wet weight required for the accurate 8-hydroxydeoxyguanosine analysis was 25 mg. The present results indicate that routine and reliable assessment of the involvement of oxidative DNA damage in the development of various diseases, including cancer, is feasible using a variety of tissue sources.


2. DOCID:23870 SCORE: 0.00449690246118673
DOCNO: 7816410
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Breast Self-Examination
QUALIFIER: diagnosis
AUTHOR: W H Hindle WH
AFFILIATION: Department of Obstetrics and Gynecology, University of Southern California, Los Angeles.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Obstetrics and gynecology clinics of North America.
COUNTRY: UNITED STATES
TITLE: The diagnostic evaluation.
PUBDATE: 19940901
Breast symptoms are appropriately evaluated by a breast-oriented history and by the diagnostic triad of clinical breast examination, FNA, and mammography. In the case of a palpable dominant mass, concordance of the diagnostic triad yields a reliable clinical diagnosis. If there is not concordance, or if there is any doubt about the diagnosis either on the part of the physician or the patient, open surgical biopsy provides the definitive histologic diagnosis. The goal in clinical practice is to detect nonpalpable cancers by ordering screening mammography for all patients eligible by age, history, or both. The long-term cancer-free survival of women treated for nonpalpable breast cancer is excellent.


3. DOCID:19930 SCORE: 0.00442590954186466
DOCNO: 2305043
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Statistical
QUALIFIER: epidemiology
QUALIFIER: adverse effects
QUALIFIER: epidemiology
AUTHOR: S A Feig SA
AUTHOR: S M Ehrlich SM
AFFILIATION: Department of Radiology, Jefferson Medical College and Thomas Jefferson University Hospital, Philadelphia, PA 19107.
PUBTYPE: Journal Article
JOURNALTITLE: Radiology.
COUNTRY: UNITED STATES
TITLE: Estimation of radiation risk from screening mammography: recent trends and comparison with expected benefits.
PUBDATE: 19900301
On the basis of recent epidemiologic studies, the National Institutes of Health in 1985 provided a new estimate for radiation risk to the breast that employed a relative risk model and acknowledged greater dependence on age at exposure. Lifetime risks from a single mammogram may be calculated from this estimate and are lower than those based on the previous 1977 National Cancer Institute estimate. Possible years of life expectancy lost from annual mammography beginning at age 40 years may also be calculated and are negligible compared with estimates for years of life expectancy gained from such screening.


4. DOCID:18521 SCORE: 0.00441562281213178
DOCNO: 2084339
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: therapeutic use
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: drug therapy
AUTHOR: E V Gembitskiĭ EV
AUTHOR: A S Portnoĭ AS
AUTHOR: A V Begunov AV
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia meditsina.
COUNTRY: USSR
TITLE: [Diagnosis and therapeutic correction of changes in the cardiovascular system of patients with prostatic cancer treated with estrogens]
PUBDATE: 19901201
Estrogen-related cardiovascular dysfunction was noted in 23 out of 30 patients with prostatic cancer (PC). Coronary subjects with PC suffered from cardiac pain evident on ECG necessitating correction by effective doses of coronary active drugs. PC patients with essential hypertension exhibited frequent headache, progressive edema of the legs, drastic hypertensive reactions. It is held that estrogen therapy for prostatic cancer should be preceded and monitored by therapeutic evaluation responsible for optimal conditions to prevent and early diagnose cardiovascular complications.


5. DOCID:19291 SCORE: 0.00436241714472716
DOCNO: 8393415
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Virus Cultivation
QUALIFIER: growth & development
AUTHOR: O Faff O
AUTHOR: B A Murray BA
AUTHOR: V Erfle V
AUTHOR: R Hehlmann R
AFFILIATION: Medizinische Poliklinik, Universität München, FRG.
PUBTYPE: Journal Article
JOURNALTITLE: FEMS microbiology letters.
COUNTRY: NETHERLANDS
TITLE: Large scale production and purification of human retrovirus-like particles related to the mouse mammary tumor virus.
PUBDATE: 19930501
Human retrovirus-like particles related to mouse mammary tumor virus (MMTV) are secreted in a steroid-dependent manner by the breast cancer cell line T47D. We report the successful large scale production and purification of these particles from culture supernatants of T47D cells and describe the experimental conditions established for this purpose. Thus, mg amounts of particles were produced by large scale culturing of T47D cells in an autoharvesting roller bottle system and purified by differential centrifugation and continuous flow ultracentrifugation on density gradients with a 50% recovery and a 350-fold enrichment.


6. DOCID:22294 SCORE: 0.00422503384471498
DOCNO: 8546457
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: economics
QUALIFIER: economics
QUALIFIER: therapy
AUTHOR: N Koinuma N
AFFILIATION: Dept. of Hospital and Health Care Administration, Tohoku University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Cancer and health economics]
PUBDATE: 19960101
Health economics on cancer medicine is a supportive tool of cancer care and is becoming one of the essential weapons against cancer. Its principal roles are to enhance the quality and efficacy and to secure the finance necessary to the cancer care. The economic aspects of cancer medicine and the methods of economic evaluation are overviewed with emphasis on cost-benefit, cost-effectiveness and cost-utility analysis. The operational and interpretational checkpoints are introduced, and the problems and prospects of the practical use of the methods on clinical settings such as cancer chemotherapy are discussed.


7. DOCID:25393 SCORE: 0.00414605111602467
DOCNO: 11253600
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: pathology
QUALIFIER: therapy
AUTHOR: O Choy O
AUTHOR: T Jahan T
AUTHOR: M Roach M
AUTHOR: L You L
AUTHOR: D Jablons D
AFFILIATION: Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest surgery clinics of North America.
COUNTRY: United States
TITLE: Stage II (N1) lung cancer.
PUBDATE: 20010201
As therapies evolve and mature, the authors predict that the next 20 years will see significant advances in the understanding of non-small-cell lung cancer (NSCLC), in molecular stratification of NSCLC, and significant improvement in survival and cure rates. This survival will be achieved through early detection and combined treatments using effective surgical interventions, improved radiotherapeutics, and especially significantly enhanced, rationally designed systemic therapies.


8. DOCID:22903 SCORE: 0.00412596398184603
DOCNO: 8655866
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Eating
DESCRIPTOR: Nutrition
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: K J Joshipura KJ
AUTHOR: W C Willett WC
AUTHOR: C W Douglass CW
AFFILIATION: Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Mass. 02115, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Dental Association (1939)
COUNTRY: UNITED STATES
TITLE: The impact of edentulousness on food and nutrient intake.
PUBDATE: 19960401
The authors collected dietary intake data about the food and nutrient intake of 49,501 male health professionals. Edentulous participants consumed fewer vegetables, less fiber and carotene, and more cholesterol, saturated fat and calories than participants with 25 or more teeth. These factors could increase the risks of cancer and cardiovascular disease. Mean differences in intake ranged from 2 to 13 percent, independent of age, smoking, exercise and profession. Longitudinal analyses suggest that tooth loss may lead to detrimental changes in diet.


9. DOCID:26211 SCORE: 0.00401377504492008
DOCNO: 11189691
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
DESCRIPTOR: Randomized Controlled Trials
DESCRIPTOR: Survival Analysis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: A B Miller AB
AUTHOR: S Yurgalevitch S
AUTHOR: J L Weissfeld JL
AFFILIATION: Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
PUBTYPE: Journal Article
JOURNALTITLE: Controlled clinical trials.
COUNTRY: United States
TITLE: Death review process in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
PUBDATE: 20001201
The procedures that have been adopted in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial are described. These procedures have been designed to ensure unbiased decisions on the underlying cause of death for all confirmed or suspected PLCO cancers. A death review committee with a nonvoting chair and three experienced reviewers as members has been appointed. After an initial pilot study, the procedures have been instituted and are working well.


10. DOCID:21475 SCORE: 0.00389348730007232
DOCNO: 8765942
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: blood supply
QUALIFIER: therapy
AUTHOR: H M Hoogewoud HM
AFFILIATION: Department Radiologie, Kantonsspital Freiburg.
PUBTYPE: Journal Article
JOURNALTITLE: Schweizerische medizinische Wochenschrift.
COUNTRY: SWITZERLAND
TITLE: [Transvascular percutaneous intervention in tumors: principles and indications]
PUBDATE: 19960701
The techniques of interventional radiology in cancer therapy have been known for several years. Like other radiologic specialties it has benefited from rapid developments in imaging and catheter technology. The indications for percutaneous vascular therapy of tumors are generally palliative and have a curative intention only in rare conditions. Interventional techniques are useful in therapy of tumor bleeding and preoperatively to lessen the risk of hemorrhage. They effectively reduce tumor bulk and provide symptomatic relief. The techniques, indications, results and complications of transvascular therapy of tumors are described.


11. DOCID:21440 SCORE: 0.00389347932795224
DOCNO: 8991583
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: M Espié M
AUTHOR: C Cuvier C
AFFILIATION: Hôpital Saint-Louis, Paris.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Contraception, fertilité, sexualité (1992)
COUNTRY: FRANCE
TITLE: [Treatment of breast cancer during pregnancy]
PUBDATE: 19961101
Breast cancer occurring during pregnancy is a rare clinical situation. A multidisciplinary approach is needed involving an obstetrician a medical oncologist and a surgeon. It should be treated according to the same principles applied in non pregnant patients. Abortion or termination of pregnancy don't improve survival. Decisions regarding abortion should be based on the desires of the patient and on therapeutic necessities. Surgery if necessary is always possible, radiation therapy should be avoided by reason of fetal toxicity, chemotherapy if absolutely necessary is possible after the first trimester.


12. DOCID:21212 SCORE: 0.00379029432311364
DOCNO: 8092120
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: L G Feun LG
AUTHOR: N Savaraj N
AUTHOR: P Benedetto P
AUTHOR: S Waldman S
AUTHOR: M Collier M
AUTHOR: N J Clendennin NJ
AFFILIATION: Sylvester Comprehensive Cancer Center, University of Miami, Florida 33136.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology.
COUNTRY: UNITED STATES
TITLE: Oral piritrexim in advanced bladder cancer: an effective drug after progression on MVAC chemotherapy?
PUBDATE: 19941001
Four patients with advanced or metastatic bladder cancer progressing after MVAC chemotherapy were treated with oral piritrexim. Three of the four patients were evaluable for response, and all three had a partial response to treatment. Piritrexim may be an effective drug for bladder cancer after progression on MVAC chemotherapy.


13. DOCID:21172 SCORE: 0.00379025967980319
DOCNO: 9006610
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Health Services Accessibility
QUALIFIER: therapy
QUALIFIER: statistics & numerical data
AUTHOR: B R Tulloh BR
AUTHOR: M E Goldsworthy ME
AFFILIATION: Echuca Regional Health, VIC.
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Australia.
COUNTRY: AUSTRALIA
TITLE: Breast cancer management: a rural perspective.
PUBDATE: 19970101
Audit of a general surgical practice in the rural Victorian town of Echuca identified 28 new patients with breast cancer between September 1992 and August 1995 (10% of those with breast conditions). The rural setting was no impediment to breast conservation (achieved in 68% of the 25 who had surgery) or to a multidisciplinary approach (management was planned in conjunction with an oncologist and/or specialist breast surgeon for 26 of the 28 patients).


14. DOCID:25389 SCORE: 0.00378576817348553
DOCNO: 11431932
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: Y Kaji Y
AUTHOR: K Sugimura K
AFFILIATION: Department of Radiology, Kobe University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica.
COUNTRY: Japan
TITLE: [Diagnostic imaging in male pelvic disorders]
PUBDATE: 20010501
This article reviews the imaging findings of male pelvic disorders, especially those of prostate disease. Magnetic resonance imaging (MRI) provides excellent anatomical detail, and is useful to stage prostate cancer and to understand the process of anomaly. However, failure to detect capsular invasion remains a significant weakness in prostate cancer. It is important to understand the limits and contributions of MRI to the staging of prostate cancer, and to perform the appropriate examination.