0. DOCID:18824 SCORE: 0.00241691483493225
DOCNO: 2260877
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: therapeutic use
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: therapeutic use
AUTHOR: K Kanda K
AUTHOR: S Waki S
AUTHOR: M Uchimura M
AUTHOR: H Kida H
AUTHOR: K Narita K
AUTHOR: N Harada N
AFFILIATION: Dept. of Surgery, Hamamatsu Medical Center.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of bone and lung metastasis of breast cancer successfully treated with radiotherapy, chemotherapy and endocrine therapy]
PUBDATE: 19901201
A 34-year-old female patient with breast cancer metastasizing to bone had a remission after a course of treatment with medroxyprogesterone acetate (MPA) 1,200 mg/day, but again had a metastasis to the lungs. The patient was then instituted on a combination therapy with UFT 400 mg/day, and MPA 1,200 mg/day. As a result, the pulmonary metastasis disappeared, along with the consolidation of the bone involved.

1. DOCID:19662 SCORE: 0.00193971214723087
DOCNO: 8462335
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: R J Mayer RJ
AFFILIATION: Dana-Farber Cancer Institute, Harvard Medical School, Boston 02115.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: Overview: the changing nature of esophageal cancer.
PUBDATE: 19930401
Squamous cell carcinomas of the esophagus, while still frequent in many locations throughout the world, now comprise a smaller percentage of esophageal cancers in the United States than was previously believed. Such tumors occur most often in black men and in association with tobacco and alcohol abuse. Adenocarcinomas of the distal esophagus represent an increasing proportion of esophageal tumors. These neoplasms arise in columnar epithelium (ie, Barrett's esophagus) or extend into the esophagus from their site of origin in the proximal stomach. Esophageal adenocarcinomas appear more often in white than black subjects and in men more than women. The clinical features and diagnostic approaches to squamous cell tumors and adenocarcinomas of the esophagus are similar.

2. DOCID:19095 SCORE: 0.00184093983641918
DOCNO: 8262160
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: physiopathology
QUALIFIER: physiopathology
QUALIFIER: physiology
AUTHOR: A Frankel A
AUTHOR: J Viallet J
AFFILIATION: Department of Medicine, Montreal General Hospital, PQ, Canada.
PUBTYPE: Journal Article
JOURNALTITLE: Experimental cell research.
COUNTRY: UNITED STATES
TITLE: Protein kinase C is not involved in the homologous desensitization of bombesin responses in small cell lung cancer cells.
PUBDATE: 19931201
Homologous desensitization of responses to bombesin in small cell lung cancer cells can be mimicked by protein kinase C-activating phorbol esters. We show that phorbol ester-induced desensitization can be blocked by prior treatment with the protein kinase C inhibitor staurosporine or prolonged pretreatment with phorbol esters. However, under these conditions, homologous desensitization to bombesin persists. These data indicate that phorbol ester-induced desensitization is distinguishable from bombesin-induced homologous desensitization. Protein kinase C is not a dominant component in the homologous desensitization to bombesin in small cell lung cancer cells.

3. DOCID:19479 SCORE: 0.00169139726636092
DOCNO: 1408964
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: standards
QUALIFIER: standards
QUALIFIER: standards
QUALIFIER: education
AUTHOR: M Pierce M
PUBTYPE: Journal Article
JOURNALTITLE: Oncology nursing forum.
COUNTRY: UNITED STATES
TITLE: Undergraduate preparation of the oncology nurse.
PUBDATE: 19920901
Determining appropriate cancer-related content for undergraduate nursing curricula requires careful consideration of content that is needed versus content that is desired for the nurse generalist. Studies have indicated a wide variety of topics and time allotment for this content among schools of nursing. Innovative strategies using games, computers, preceptors, and elective courses have allowed schools of nursing to include more comprehensive coverage of oncology-related topics. Issues concerning clinical oncology nursing opportunities for undergraduate studies still need to be clarified. Undergraduate students must be afforded the legitimacy of their status as novices in nursing and in the specialty of oncology. Didactic and clinical experiences should result in the knowledge and skills needed to develop professionally from novice to expert.

4. DOCID:18737 SCORE: 0.00152772102021505
DOCNO: 1955182
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: J W Orr JW
AUTHOR: R W Holloway RW
AUTHOR: P F Orr PF
AUTHOR: J L Holimon JL
AFFILIATION: Department of Gynecology and Obstetrics, Watson Clinic, Lakeland, Florida 33805.
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Surgical staging of uterine cancer: an analysis of perioperative morbidity.
PUBDATE: 19910901
Surgical staging documented extrauterine disease in 27.9% of 168 patients with apparent early-clinical-stage uterine cancer. An analysis of operative time (78 +/- 21 min), blood loss (332 +/- 160 cc), and surgical site infection risks (4.7%) indicated little additional risk of lymphadenectomy. The long-term risk of lymphocyst (1.3%) or lymphedema (0.7%) was small. The histologic information obtained from staging was utilized to rationally guide the need for adjunctive teletherapy. The overall risk of recurrence (median follow-up, 26 months) with surgical Stage I disease was 2.6%.

5. DOCID:19806 SCORE: 0.00147903648527824
DOCNO: 1838700
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: J Brisson J
AFFILIATION: Department of Social and Preventive Medicine, Laval University, Quebec, Canada.
PUBTYPE: Journal Article
PUBTYPE: Meta-Analysis
JOURNALTITLE: Epidemiology (Cambridge, Mass.)
COUNTRY: UNITED STATES
TITLE: Family history of breast cancer, mammographic features of breast tissue, and breast cancer risk.
PUBDATE: 19911101
I reexamined the relations of family history of breast cancer in first-degree relatives, mammographic features of breast tissue, and breast cancer risk, using data from three case-control studies. Subjects included 1,047 cases with newly diagnosed breast cancer and 2,329 controls. Family history of breast cancer showed only a weak relation to mammographic features. In addition, while family history and mammographic features were each related to breast cancer risk, associations of these two factors with risk appeared additive. In contrast to previous reports, these data suggest that, to a large extent, family history and mammographic features have independent effects on breast cancer development.

6. DOCID:17301 SCORE: 0.00147715085006436
DOCNO: 1866508
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: physiopathology
QUALIFIER: therapy
AUTHOR: D A Lossignol DA
AFFILIATION: Service de médecine interne, Institut Jules Bordet, Bruxelles.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale de Bruxelles.
COUNTRY: BELGIUM
TITLE: [Pain and cancer]
PUBDATE: 19910601
Pain is one of the most frequent symptoms encountered in oncology which, regarding its complexity and its effects on quality of life, will be better treated with a multidisciplinary approach, for in and out-patients. The knowledge of the pain syndromes associated with an accurate use of pain medicine provide a rapid control of the symptomatology. A coherent use of opioids, the introduction of new drug delivery systems, and the use of new molecules offer new horizons in the control of cancer pain.

7. DOCID:16426 SCORE: 0.00145412505967784
DOCNO: 2068655
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: J Kahlhöfer J
AFFILIATION: Friedrich-Ebert-Krankenhaus, Radiologische Klinik, Neumünster.
PUBTYPE: Journal Article
JOURNALTITLE: Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al].
COUNTRY: GERMANY
TITLE: [An improved method for the radiotherapy of breast carcinoma]
PUBDATE: 19910601
This method of radiotherapy of the breast and lymph nodes in cases of breast cancer reduces exposure of the lung and features small gaps and overlaps at the borders of neighbouring fields. The outline of fields, the design of special absorbing blocks and filters, and some notes on treatment planning are given in this paper.

8. DOCID:17907 SCORE: 0.00144985115986921
DOCNO: 2314900
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cell Transformation, Neoplastic
DESCRIPTOR: Genes
DESCRIPTOR: Transfection
QUALIFIER: genetics
AUTHOR: Y Maru Y
AUTHOR: H Hirai H
AUTHOR: F Takaku F
AFFILIATION: Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Oncogene.
COUNTRY: ENGLAND
TITLE: Overexpression confers an oncogenic potential upon the eph gene.
PUBDATE: 19900301
The eph gene encodes a putative receptor tyrosine kinase for an as yet unknown ligand. Some human cancer cells have been found to overexpress eph mRNAs without gene amplification. We show here that NIH3T3 cells acquire tumorigenic ability in nude mice and make colonies in soft agar with a viral LTR (Long Terminal Repeat)-driven artificial expression of the eph gene to a high level. This result supports the alleged contribution of overexpressed receptor tyrosine kinases to cell transformation.

9. DOCID:19351 SCORE: 0.00139340232424408
DOCNO: 2335383
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: diagnosis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: blood
QUALIFIER: blood
AUTHOR: D G Zaridze DG
AUTHOR: V E Chevchenko VE
AUTHOR: A A Levtshuk AA
AUTHOR: Y E Lifanova YE
AUTHOR: D M Maximovitch DM
AFFILIATION: Department of Cancer Epidemiology and Prevention, USSR Academy of Medical Sciences, Moscow.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: UNITED STATES
TITLE: Fatty acid composition of phospholipids in erythrocyte membranes and risk of breast cancer.
PUBDATE: 19900501
Five fatty acids (FA) 2 saturated, palmitic (C16:0), stearic (C18:0) and 3 unsaturated, oleic (C18:1), linoleic (C18:2), arachidonic (C20:4) acids have been studied in the red cell membranes of breast cancer patients and controls. Statistically significant decrease in the risk of breast cancer has been found to be associated with increase in the levels of linoleic acid in pre-menopausal women and of arachidonic acid in the post-menopausal group.

10. DOCID:19758 SCORE: 0.00138466628761696
DOCNO: 8364086
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: H T Lynch HT
AUTHOR: J F Lynch JF
AFFILIATION: Department of Preventive Medicine, Creighton University School of Medicine, Omaha, NE 68178.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: The Lynch syndromes.
PUBDATE: 19930701
The Lynch syndromes, also referred to as hereditary nonpolyposis colorectal cancer, are reviewed, with particular attention given to their natural history, diagnosis, surveillance, and management. Lynch syndrome I is characterized by an autosomal dominantly inherited predisposition to early onset colorectal cancer, with proximal predominance and an excess of synchronous and metachronous colorectal cancers. Lynch syndrome II manifests all of the features of Lynch syndrome I but, in addition, shows an integral association with extracolonic cancers, particularly carcinomas of the endometrium and the ovary. There are no premonitory physical signs or biomarkers of genotypic risk. Therefore, the natural history features of the Lynch syndromes are crucial to their surveillance and management.

11. DOCID:16541 SCORE: 0.0013832086935013
DOCNO: 1489558
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: secondary
AUTHOR: J H Bisese JH
AFFILIATION: Physicians' Spine Center, Atlanta, GA 30342.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in ultrasound, CT, and MR.
COUNTRY: UNITED STATES
TITLE: MRI of cranial metastasis.
PUBDATE: 19921201
Recent advances in surgical techniques and new innovations in radiation treatment and chemotherapy have made the detection and characterization of intracranial metastasis increasingly important in the management of the cancer patient. This article reviews the more common sources of metastasis, their appearance, and more unusual types of involvement such as hemorrhage and spread to the leptomeninges and bony calvarium.

12. DOCID:18961 SCORE: 0.00138241073705565
DOCNO: 1785427
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: administration & dosage
AUTHOR: T Hattori T
AUTHOR: M Satoh M
AUTHOR: Y Terashima Y
AUTHOR: T Nishimura T
AUTHOR: M Akimoto M
AFFILIATION: Department of Urology, Nippon Medical School.
PUBTYPE: Journal Article
JOURNALTITLE: Hinyokika kiyo. Acta urologica Japonica.
COUNTRY: JAPAN
TITLE: [The activity of etoposide (VP16) in combination chemotherapy against human bladder cancer cells in vitro]
PUBDATE: 19910901
The activity of Etoposide (VP16) in combination chemotherapy against four human transitional cell carcinoma cell lines of bladder (TCCaB) was determined by in vitro colony formation assay. Four anti-tumor agents (methotrexate: MTX, vinblastine: VBL, adriamycin: ADM, cisplatin: DDP) were used for combination chemotherapy with VP16. The ADM + VP16 combination exhibited a strong synergistic antitumor effect against the human TCCaBs compared with other combinations in this study. The combination chemotherapy of ADM + VP16 may be useful as a new chemotherapeutic regimen for advanced bladder cancer.

13. DOCID:18441 SCORE: 0.00137643756999333
DOCNO: 2012022
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Dietary Fats
DESCRIPTOR: Fats
DESCRIPTOR: Plant Oils
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: R C Cottrell RC
AFFILIATION: Leatherhead Food Research Association, Surrey, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The American journal of clinical nutrition.
COUNTRY: UNITED STATES
TITLE: Introduction: nutritional aspects of palm oil.
PUBDATE: 19910401
The production, composition, and food uses of palm oil are outlined in this introduction to a detailed appraisal of the nutritional and health implications of the use of palm oil in the food supply. The putative role of dietary fats and oils in general, and of palm oil in particular, in the etiology of coronary heart disease and cancer is critically assessed. It is concluded that the evidence available is difficult to interpret unambiguously. Some evidence to suggest that the minor components of palm oil might have useful biological effects is also discussed.

14. DOCID:17128 SCORE: 0.00137498670211278
DOCNO: 2065231
AUTHOR: D Franco D
AFFILIATION: Groupe de Recherche sur la Chirurgie du Foie et de l'Hypertension Portale, Université Paris XI, Hôpital Antoine Béclère, Clamart.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: British journal of hospital medicine.
COUNTRY: ENGLAND
TITLE: The management of liver metastases.
PUBDATE: 19910501
The spontaneous life expectancy of patients with liver metastases from colorectal cancers is dismaying. Surgical resection is the only treatment which may help these patients. After resection the 5-year survival rate averages 25%. The best results are obtained in patients with one or few metastases localized to one liver lobe. There is no effective adjuvant therapy. Systemic or regional chemotherapy and immunomodulation have little effect in patients with inoperable metastases.