0. DOCID:18824 SCORE: 0.00241691483493225
DOCNO: 2260877
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: therapeutic use
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: therapeutic use
AUTHOR: K Kanda K
AUTHOR: S Waki S
AUTHOR: M Uchimura M
AUTHOR: H Kida H
AUTHOR: K Narita K
AUTHOR: N Harada N
AFFILIATION: Dept. of Surgery, Hamamatsu Medical Center.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of bone and lung metastasis of breast cancer successfully treated with radiotherapy, chemotherapy and endocrine therapy]
PUBDATE: 19901201
A 34-year-old female patient with breast cancer metastasizing to bone had a remission after a course of treatment with medroxyprogesterone acetate (MPA) 1,200 mg/day, but again had a metastasis to the lungs. The patient was then instituted on a combination therapy with UFT 400 mg/day, and MPA 1,200 mg/day. As a result, the pulmonary metastasis disappeared, along with the consolidation of the bone involved.


1. DOCID:23046 SCORE: 0.00225422990060723
DOCNO: 9234939
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: G H Eltabbakh GH
AUTHOR: M S Piver MS
AUTHOR: B A Werness BA
AFFILIATION: Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Primary peritoneal adenocarcinoma metastatic to the brain.
PUBDATE: 19970701
Primary peritoneal adenocarcinoma is a relatively newly identified disease entity whose clinical behavior is not fully recognized. We report a case of a patient with progressive primary peritoneal adenocarcinoma who developed brain metastases and died shortly afterward. The incidence of central nervous system metastases in 72 patients with documented primary peritoneal adenocarcinoma was 1.4%. The risk factors, clinical behavior, and prognosis of patients with primary peritoneal adenocarcinoma metastatic to the central nervous system seem to be similar to those of patients with epithelial ovarian cancer metastatic to the central nervous system.


2. DOCID:23854 SCORE: 0.00196556999262513
DOCNO: 7661586
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: Y Sun Y
AUTHOR: X R Zhang XR
AUTHOR: W B Yin WB
AUTHOR: D F Chen DF
AUTHOR: R G Zhang RG
AUTHOR: D W Zhang DW
AFFILIATION: Department of Medical Oncology, Chinese Academy of Medical Sciences, Beijing.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: Prospective multimodality treatment of SCLC--experience during the past 18 years.
PUBDATE: 19950801
Lung cancer has been one of the leading malignancies in China. Since 1989 it has ranked first among common malignancies in the male population, and second in females. In 1975, a multimodality treatment study group for lung cancer was organized in our institute. The group has since expanded to 15 institutions in the Beijing and Tianjin area during the past four years. The present communication is based on our experiences and data, and tries to explain the treatment strategy of our study group.


3. DOCID:19662 SCORE: 0.00193971214723087
DOCNO: 8462335
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: R J Mayer RJ
AFFILIATION: Dana-Farber Cancer Institute, Harvard Medical School, Boston 02115.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: Overview: the changing nature of esophageal cancer.
PUBDATE: 19930401
Squamous cell carcinomas of the esophagus, while still frequent in many locations throughout the world, now comprise a smaller percentage of esophageal cancers in the United States than was previously believed. Such tumors occur most often in black men and in association with tobacco and alcohol abuse. Adenocarcinomas of the distal esophagus represent an increasing proportion of esophageal tumors. These neoplasms arise in columnar epithelium (ie, Barrett's esophagus) or extend into the esophagus from their site of origin in the proximal stomach. Esophageal adenocarcinomas appear more often in white than black subjects and in men more than women. The clinical features and diagnostic approaches to squamous cell tumors and adenocarcinomas of the esophagus are similar.


4. DOCID:22733 SCORE: 0.0019326156542639
DOCNO: 7664241
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Fragility
DESCRIPTOR: Occupational Exposure
QUALIFIER: toxicity
AUTHOR: I Sbrana I
AUTHOR: A Musio A
AFFILIATION: Dipartimento di Scienze dell' Ambiente e del Territorio, Università di Pisa, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Enhanced expression of common fragile site with occupational exposure to pesticides.
PUBDATE: 19950701
The expression of common fragile sites (FS), induced by aphidicolin, in subjects with occupational history of exposure to pesticides has been studied. Results showed a higher frequency of FS in exposed subjects; in particular, there was an elevated expression of FS at the cancer breakpoints 3p14, 5q31, 7q22, 7q32, 14q24, and 16q22, involved in leukemias and non-Hodgkin's lymphoma. Moreover, the frequency of breaks in chromosomal bands carrying oncogenes or tumor suppressor genes involved in aberrations was significantly higher in exposed subjects at sites 1q25, 3p25, 7p22, 8q24.1, and 13q14.


5. DOCID:19095 SCORE: 0.00184093983641918
DOCNO: 8262160
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: physiopathology
QUALIFIER: physiopathology
QUALIFIER: physiology
AUTHOR: A Frankel A
AUTHOR: J Viallet J
AFFILIATION: Department of Medicine, Montreal General Hospital, PQ, Canada.
PUBTYPE: Journal Article
JOURNALTITLE: Experimental cell research.
COUNTRY: UNITED STATES
TITLE: Protein kinase C is not involved in the homologous desensitization of bombesin responses in small cell lung cancer cells.
PUBDATE: 19931201
Homologous desensitization of responses to bombesin in small cell lung cancer cells can be mimicked by protein kinase C-activating phorbol esters. We show that phorbol ester-induced desensitization can be blocked by prior treatment with the protein kinase C inhibitor staurosporine or prolonged pretreatment with phorbol esters. However, under these conditions, homologous desensitization to bombesin persists. These data indicate that phorbol ester-induced desensitization is distinguishable from bombesin-induced homologous desensitization. Protein kinase C is not a dominant component in the homologous desensitization to bombesin in small cell lung cancer cells.


6. DOCID:23675 SCORE: 0.00178774079065306
DOCNO: 7868044
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Breast Neoplasms
DESCRIPTOR: Physician-Patient Relations
AUTHOR: K Asaishi K
AFFILIATION: Sapporo Kotoni Breast Clinic, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: [Hokkaido igaku zasshi] The Hokkaido journal of medical science.
COUNTRY: JAPAN
TITLE: [Several medical problems for ideal relationship between breast cancer patients and surgeons in Japan]
PUBDATE: 19940901
Recently, breast cancer is one of the most important disease in Japanese women. It is now recognized from prospective studies that Japanese women are at an increased risk of developing breast cancer. In this paper, the author mentioned the several problems of Q.O.L., informed consent and medical system for breast cancer patients in Japan. It is well-known that the patients with recurrent breast cancer showed low level of Q.O.L. compared with the patients free from the disease. So it is important to make a good result of the recurrent rate of conservative treatment of breast cancer as well as radical mastectomy.


7. DOCID:21706 SCORE: 0.00177665157435453
DOCNO: 7536448
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nuclear Warfare
QUALIFIER: epidemiology
AUTHOR: K Shimaoka K
AUTHOR: Y Shibata Y
AUTHOR: S Akiba S
AFFILIATION: Radiation Effects Research Foundation, Hiroshima, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Thyroidology / A.P.R.I.M.
COUNTRY: ITALY
TITLE: Thyroid diseases in cohort studies of A-bomb survivors.
PUBDATE: 19940801
A fixed population of about 120,000 subjects was selected from those A-bomb survivors and unexposed controls for the purpose of follow-up studies on their late health effects. One hundred twelve cases of thyroid cancer were found in the study period between 1958 to 1979. The relative risk increased with thyroid dose: the excess relative risk per Gray was 1.1. The prevalence of thyroid diseases was evaluated in 2,587 subjects in Nagasaki: one or more diagnoses for thyroid diseases were made in 447.


8. DOCID:23597 SCORE: 0.001753510348412
DOCNO: 9417297
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: chemistry
QUALIFIER: analysis
AUTHOR: G Sica G
AUTHOR: G Lama G
AUTHOR: C Angelucci C
AUTHOR: G Zelano G
AFFILIATION: Istituto di Istologia ed Embriologia, Facoltà Medicina e Chirurgia Università Cattolica del S. Cuore, Roma.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Archivio italiano di urologia, andrologia : organo ufficiale [di] Società italiana di ecografia urologica e nefrologica / Associazione ricerche in urologia.
COUNTRY: ITALY
TITLE: [Hormone receptors and growth factors in carcinoma of the prostate]
PUBDATE: 19970901
The therapeutic and prognostic significance of androgen receptors in prostatic carcinoma has been examined on the basis of data obtained with the different techniques used in receptor determination. Moreover, the role of some polypeptide growth factors in the regulation of prostatic cancer growth and progression has been reviewed. Great attention has been focused on in vitro models utilized to investigate androgen receptor alterations and the effects of the different positive and negative regulators of prostatic carcinoma cell growth.


9. DOCID:19479 SCORE: 0.00169139726636092
DOCNO: 1408964
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: standards
QUALIFIER: standards
QUALIFIER: standards
QUALIFIER: education
AUTHOR: M Pierce M
PUBTYPE: Journal Article
JOURNALTITLE: Oncology nursing forum.
COUNTRY: UNITED STATES
TITLE: Undergraduate preparation of the oncology nurse.
PUBDATE: 19920901
Determining appropriate cancer-related content for undergraduate nursing curricula requires careful consideration of content that is needed versus content that is desired for the nurse generalist. Studies have indicated a wide variety of topics and time allotment for this content among schools of nursing. Innovative strategies using games, computers, preceptors, and elective courses have allowed schools of nursing to include more comprehensive coverage of oncology-related topics. Issues concerning clinical oncology nursing opportunities for undergraduate studies still need to be clarified. Undergraduate students must be afforded the legitimacy of their status as novices in nursing and in the specialty of oncology. Didactic and clinical experiences should result in the knowledge and skills needed to develop professionally from novice to expert.


10. DOCID:21219 SCORE: 0.00168596800430357
DOCNO: 9244985
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: F Mosimann F
AFFILIATION: Centre hospitalier universitaire vaudois (CHUV), Lausanne.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Schweizerische medizinische Wochenschrift.
COUNTRY: SWITZERLAND
TITLE: [Surgery and cystic malformations of the bile ducts]
PUBDATE: 19970501
Bile duct cysts are usually diagnosed during infancy and childhood, although 20-30% become symptomatic in adults, sometimes as late as the seventh decade of life. The Todani modification of the Alonso-Lej classification is now generally accepted and has clarified a previously confusing literature. Treatment is surgical: resectional rather than the traditional drainage procedures are indicated. This aggressive approach decreases but does not abolish the risk of cancer in the hepato-bilio-pancreatic tree. The patients must therefore be followed up for life.


11. DOCID:21886 SCORE: 0.0016391994181862
DOCNO: 7740218
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Attitude to Death
QUALIFIER: physiopathology
QUALIFIER: psychology
AUTHOR: B R Ferrell BR
AUTHOR: G Dean G
AFFILIATION: Department of Nursing Research and Education, City of Hope National Medical Center, Duarte, CA 91010, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Seminars in oncology nursing.
COUNTRY: UNITED STATES
TITLE: The meaning of cancer pain.
PUBDATE: 19950201
Pain is a common symptom in cancer and one experienced both by patients and family caregivers. A neglected area of pain management is enhancing the individual's ability to derive the meaning from pain and suffering associated with illness. Because pain is often a metaphor for impending death, the meaning derived from pain may contribute to the ultimate meaning of death for the individual. This article provides case examples and analysis of the search for meaning in cancer pain.


12. DOCID:23607 SCORE: 0.0016386106309041
DOCNO: 9225960
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: chemistry
QUALIFIER: administration & dosage
QUALIFIER: chemistry
AUTHOR: J M Terwogt JM
AUTHOR: B Nuijen B
AUTHOR: W W Huinink WW
AUTHOR: J H Beijnen JH
AFFILIATION: Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer treatment reviews.
COUNTRY: ENGLAND
TITLE: Alternative formulations of paclitaxel.
PUBDATE: 19970301
Paclitaxel, a novel antitumour agent, is active clinically against advanced ovarian and breast cancer and under investigation for various other cancers. One of the problems associated with the intravenous administration of paclitaxel is its low solubility in water. The current pharmaceutical formulation consists of a 1:1 (v/v) mixture of ethanol and Cremophor EL. This formulation, however, has been demonstrated to cause some severe hypersensitivity reactions. Therefore the development of a safer intravenous formulation devoid of Cremophor EL is an important investigational issue. This review deals with some of the most promising formulation alternatives.


13. DOCID:22423 SCORE: 0.00163211230104498
DOCNO: 9451865
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: E Gez E
AUTHOR: Y Netzer-Horowitz Y
AUTHOR: E Waiman E
AUTHOR: R Rubinov R
AUTHOR: Y Cohen Y
AUTHOR: A Kuten A
AFFILIATION: Northern Israel Oncology Center, Rambam Medical Center, Haifa.
PUBTYPE: Journal Article
JOURNALTITLE: Harefuah.
COUNTRY: ISRAEL
TITLE: [Radiotherapy of localized prostatic carcinoma]
PUBDATE: 19971201
112 patients with localized prostate cancer, clinical stage A2-C, were treated by definitive radiotherapy between 1982-1988. Radiation volume encompassed the prostate, seminal vesicles and pelvic lymph nodes. The 10-year actuarial survival figures were: overall 51%; stage A2 87%; stage B 50%; stage C 36%; well differential tumors 67%; moderately differentiated 50%; poorly differentiated 32%; patients with local tumor control 55%; and patients with minimal local control 36%. It is concluded that external beam irradiation is effective in localized prostatic cancer. Stage and grade are prognosticators of survival.


14. DOCID:23089 SCORE: 0.00159685296860797
DOCNO: 7973637
AUTHOR: A Umar A
AUTHOR: J C Boyer JC
AUTHOR: T A Kunkel TA
AFFILIATION: Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.
PUBTYPE: Journal Article
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: DNA loop repair by human cell extracts.
PUBDATE: 19941101
An activity in human cell extracts is described that repairs DNA with loops of five or more unpaired bases. Repair is strand-specific and is directed by a nick located 5' or 3' to the loop. This repair is observed in a colorectal cancer cell line that is devoid of a wild-type hMLH1 gene and is deficient in repair of mismatches. However, a cell line with deletions in both hMSH2 alleles is deficient in repair of both loops and mismatches. Defects in loop repair may be relevant to the repetitive-sequence instability observed in cancers and other hereditary diseases.