0. DOCID:29904 SCORE: 0.00295313500319658
DOCNO: 12915920
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Helicobacter Infections
DESCRIPTOR: Helicobacter pylori
AUTHOR: Peng-Yuan Zheng PY
AUTHOR: Nicola L Jones NL
AFFILIATION: University of Toronto, Toronto, Canada.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Canadian journal of gastroenterology = Journal canadien de gastroenterologie.
COUNTRY: Canada
TITLE: Recent advances in Helicobacter pylori infection in children: from the petri dish to the playground.
PUBDATE: 20030701
Helicobacter pylori infection is acquired in childhood, plays a causative role in chronic gastritis and peptic ulcer disease, and is associated with the development of gastric cancer. The present review focuses on recent advances in the scientific knowledge of H pylori infection in children, including clinical sequelae, diagnosis and treatment. In addition, recent insights regarding both bacterial and host factors that mediate human diseases associated with H pylori infection are discussed.


1. DOCID:31359 SCORE: 0.0029180346582523
DOCNO: 16178544
OWNER: NLM
STATUS: In-Process
AUTHOR: Amos B Smith AB
AUTHOR: Thomas M Razler TM
AUTHOR: George R Pettit GR
AUTHOR: Jean-Charles Chapuis JC
AFFILIATION: Department of Chemistry, Monell Chemical Senses Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. smithab@sas.upenn.edu
PUBTYPE: Journal Article
JOURNALTITLE: Organic letters.
COUNTRY: United States
TITLE: (+)-Phorboxazole A synthetic studies. Identification of a series of highly cytotoxic C(45-46) analogues.
PUBDATE: 20050901
[structure: see text] Effective, scalable total syntheses and biological evaluation of six phorboxazole A analogues (1-6) have been achieved. Importantly, the C(45-46)-saturated, C(45-46)-alkenyl, and the C(45-46)-E-chloroalkenyl congeners (4, 5, and 6, respectively) reveal low nanomolar tumor cell growth inhibitory activity (GI50's) similar to or, in some cell lines, greater than that of the phorboxazoles across a diverse panel of human cancer cell lines.


2. DOCID:29931 SCORE: 0.002876112066483
DOCNO: 11901908
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: pathology
AUTHOR: Peter Mazzone P
AUTHOR: Prasoon Jain P
AUTHOR: Alejandro C Arroliga AC
AUTHOR: Richard A Matthay RA
AFFILIATION: Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Clinics in chest medicine.
COUNTRY: United States
TITLE: Bronchoscopy and needle biopsy techniques for diagnosis and staging of lung cancer.
PUBDATE: 20020301
Lung cancer is the leading cause of cancer deaths in the United States. The individual therapeutic approach and prognosis depends on accurate diagnosis and staging. Flexible bronchoscopy (FB) and transthoracic needle biopsy (TNB) are the most widely used techniques for this purpose. This article provides a critical overview of indications, diagnostic yield, and limitations of bronchoscopy and TNB in the diagnosis of lung cancer.


3. DOCID:29740 SCORE: 0.00268122344304991
DOCNO: 12537239
AUTHOR: Kohsuke Tayama K
AUTHOR: Naofumi Eriguchi N
AUTHOR: Yasuhiko Futamata Y
AUTHOR: Hiroshi Harada H
AUTHOR: Atsushi Yoshida A
AUTHOR: Akira Matsunaga A
AUTHOR: Masahiro Mitsuoka M
AFFILIATION: Department of Surgery, Sasebo Kyohsai Hospital, Sasebo, Japan. ktayama@kkr.sasebo.nagasaki.jp
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Annals of thoracic surgery.
COUNTRY: United States
TITLE: Modified Dumon stent for the treatment of a bronchopleural fistula after pneumonectomy.
PUBDATE: 20030101
We describe the case of a 72-year-old man in whom a bronchopleural fistula developed after induction chemotherapy followed by right pneumonectomy for lung cancer. Resuturing of the right main bronchial stump, endoscopic treatment, and repair using a latissimus dorsi muscle flap were not effective. Consequently we placed a modified Dumon stent in the carina, which effectively closed the stump.


4. DOCID:30852 SCORE: 0.00264673999284844
DOCNO: 12778018
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Quality of Life
QUALIFIER: pathology
QUALIFIER: therapy
QUALIFIER: pathology
QUALIFIER: therapy
AUTHOR: Beth A Hellerstedt BA
AUTHOR: Kenneth J Pienta KJ
AFFILIATION: University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: United States
TITLE: Germ cell tumors: review of selected studies from 2002.
PUBDATE: 20030501
Testicular cancer remains a major success story in the realm of solid tumors. There are still many remaining challenges in diagnosis, treatment, and prevention of long-term toxicity. Surgery and platinum-based chemotherapy, however, still encompass the main treatment modalities. Attempts to limit toxicity from both surgery and chemotherapy remain at the forefront of research. New chemotherapeutic options are available for patients with platinum-resistant disease, and stem cell transplant remains an area of active study.


5. DOCID:31438 SCORE: 0.00257033151138941
DOCNO: 12484077
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusions, Intra-Arterial
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: analogs & derivatives
QUALIFIER: drug therapy
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: Tatsuro Yamaguchi T
AUTHOR: Takeo Mori T
AUTHOR: Keiichi Takahashi K
AUTHOR: Masayuki Ohue M
AUTHOR: Shigenori Homma S
AUTHOR: Kuniyoshi Arai K
AUTHOR: Yoshiaki Iwasaki Y
AUTHOR: Yutaka Kimura Y
AFFILIATION: Dept. of Surgery, Tokyo Metropolitan Komagome Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Hepatic arterial infusion with irinotecan for the colorectal cancer patient with liver metastasis--a case report]
PUBDATE: 20021101
A 53-year-old woman who had been treated for rectal cancer was admitted to our hospital with edema, abdominal distension, and general fatigue. Abdominal CT showed multiple liver metastases and paraaortic lymph node metastases. After she was administered irinotecan by hepatic arterial infusion, the liver metastases decreased and paraaortic lymph node metastases were remarkably reduced in size.


6. DOCID:31473 SCORE: 0.00256056339476041
DOCNO: 16324870
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: M Espié M
AUTHOR: H Hocini H
AUTHOR: C Cuvier C
AUTHOR: S Giacchetti S
AUTHOR: E Bourstyn E
AUTHOR: A de Roquancourt A
AFFILIATION: Centre des maladies du sein, hôpital Saint-Louis, Paris, France. marc.espie@sls.ap-hop-paris.fr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gynécologie, obstétrique & fertilité.
COUNTRY: France
TITLE: [Breast lobular carcinoma in situ: diagnosis and evolution]
PUBDATE: 20051201
The incidence of lobular cancers in situ is increasing, especially in post-menopausal women. Whereas this form of disease was regarded for a long time as nothing but a risk factor of the occurrence of later infiltrating carcinoma, it now tends to represent a precancerous state whose progression to subsequent infiltrating carcinoma does not inevitably occur. The clinical and radiological diagnosis remains difficult and the choice of therapies varies according to teams, ranging from mere surveillance to mastectomy.


7. DOCID:31362 SCORE: 0.00256055589529856
DOCNO: 15496272
OWNER: NLM
STATUS: In-Process
AUTHOR: Ralph V Boccia RV
AFFILIATION: Center for Cancer and Blood Disorders, Bethesda, MD, USA. bocciar@comcast.net
PUBTYPE: Journal Article
JOURNALTITLE: Current hematology reports.
COUNTRY: United States
TITLE: Erythropoietic agents in chemotherapy-induced anemia: a review of recent therapeutic progress, issues, and concerns.
PUBDATE: 20041101
Erythropoietic agents are widely used to alleviate anemia in patients with cancer receiving chemotherapy. Over the past decade, the efficacy and safety of these agents in improving hemoglobin levels and reducing transfusion requirements in an oncology setting has been demonstrated in a number of clinical trials. The overall risk-benefit relationship of treatment with erythropoietic agents is favorable, and these agents represent a tremendous advance in anemia management. This review discusses prevalent issues and addresses key questions concerning the use of erythropoietic agents for the treatment of chemotherapy-induced anemia.


8. DOCID:29284 SCORE: 0.00236988858148355
DOCNO: 16267711
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: T Höhler T
AUTHOR: M Heike M
AUTHOR: M P Lutz MP
AUTHOR: U Graeven U
AUTHOR: T Seufferlein T
AFFILIATION: Prosper Hospital Recklinghausen.
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Gastroenterologie.
COUNTRY: Germany
TITLE: [ASCO-Update 2005 - Highlights of the 41st Meeting of the American Society of Clinical Oncology/ASCO 2005.]
PUBDATE: 20051101
Currently, the treatment of gastrointestinal cancers is rapidly changing due to the implementation of novel chemotherapeutic agents as well as the introduction of targeted therapies into treatment protocols. The following review provides an overview of the most important clinical trials in esophageal, gastric, colorectal, pancreatic and hepatobiliary cancer that were presented at the annual meeting of the American Society of Clinical Oncology.


9. DOCID:29040 SCORE: 0.00236988790539379
DOCNO: 16336092
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: pathology
QUALIFIER: genetics
QUALIFIER: pathology
QUALIFIER: physiopathology
AUTHOR: Hashim Uddin Ahmed HU
AUTHOR: Manit Arya M
AUTHOR: Hitendra R H Patel HR
AFFILIATION: Institute of Urology, University College London Hospitals, London, UK. hashim_uddin_ahmed@hotmail.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Expert review of anticancer therapy.
COUNTRY: England
TITLE: Bladder carcinoma: understanding advanced and metastatic disease with potential molecular therapeutic targets.
PUBDATE: 20051201
This article is an expert review of bladder cancer genetics focusing on genetic changes and their significance in the pathogenesis and progression of bladder transitional cell carcinoma, in particular, muscle-invasive disease. Alongside the relevant genetic markers and their products, new therapeutic targets and agents that are being developed are presented.


10. DOCID:29037 SCORE: 0.00236988786533023
DOCNO: 16144894
PUBTYPE: Consensus Development Conference
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Annals of internal medicine.
COUNTRY: United States
TITLE: Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: recommendation statement.
PUBDATE: 20050901
This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility, along with the supporting scientific evidence. The complete information on which this statement is based, including evidence tables and references, is included in the evidence synthesis available through the USPSTF Web site (http://www.preventiveservices.ahrq.gov). The recommendation is also posted on the Web site of the National Guideline Clearinghouse (http://www.guideline.gov).


11. DOCID:31681 SCORE: 0.00229183328943428
DOCNO: 12910424
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laser Coagulation
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: B Sauer B
AUTHOR: M Staritz M
AFFILIATION: Klinik für Innere Medizin 1, Klinikum der Stadt Villingen-Schwenningen, Germany. img.bernd.sauer@klinikumvs.de
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Gastroenterologie.
COUNTRY: Germany
TITLE: [Palliative laser therapy of colorectal cancer with sustained local tumor removal]
PUBDATE: 20030801
Laser photocoagulation is an established palliative therapeutic method in advanced colorectal cancer. In most cases tumor obstruction of the colonic lumen and symptoms like bleeding, secretion and diarrhoea can be improved or prevented. Even curative tumor therapy of some patients has been reported, particularly in cases with superficial growth of the tumor. We report about an elderly female patient with locally advanced invasive carcinoma of the rectosigmoidal junction. This tumor and a polypoid carcinoma of the sigmoid, possibly in combination with snare resection, were persistently removed by laser photocoagulation.


12. DOCID:31288 SCORE: 0.0022479658554167
DOCNO: 12893358
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: agonists
QUALIFIER: chemically induced
QUALIFIER: chemically induced
AUTHOR: Keith L Lee KL
AUTHOR: Martha K Terris MK
AFFILIATION: Department of Urology, Stanford University Medical Center, Stanford, California, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: Urology.
COUNTRY: United States
TITLE: Luteinizing hormone-releasing hormone agonists and meningioma: a treatment dilemma.
PUBDATE: 20030801
The relative contraindication of hormonal therapy for patients with prostate cancer and a history of meningioma has not been widely emphasized. Using immunohistochemistry to determine the presence of hormone receptors in meningioma specimens proved potentially valuable in 2 patients with biochemical recurrence after prostatectomy who were being considered for androgen deprivation therapy. These cases also highlight the need for caution against assuming that skull-based intracranial growths in patients receiving hormonal therapy for prostate cancer are metastatic lesions rather than hormonally induced primary tumors.


13. DOCID:31045 SCORE: 0.002235839244837
DOCNO: 16143160
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: analogs & derivatives
QUALIFIER: drug therapy
AUTHOR: Howard A Burris HA
AFFILIATION: The Sarah Cannon Cancer Center and Tennessee Oncology, PLLC, Nashville, USA. hburris@tnonc.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: United States
TITLE: Recent updates on the role of chemotherapy in pancreatic cancer.
PUBDATE: 20050801
Single-agent gemcitabine remains the standard treatment for advanced pancreatic cancer. Recent phase III trials have failed to show improvements in survival using gemcitabine in combination with other chemotherapeutic agents, although the gemcitabine/oxaliplatin combination has shown some promise. The combination of gemcitabine with erlotinib was associated with a significant prolongation of survival. Promising results in a phase II trial of gemcitabine in combination with bevacizumab have led to a randomized comparative trial of the combination. Potential combinations with other biologic agents are being investigated.


14. DOCID:29921 SCORE: 0.0022314127898155
DOCNO: 12407698
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: Avery A Sandberg AA
AFFILIATION: Department of DNA Diagnostics at St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA. jvaugha@chw.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: American journal of medical genetics.
COUNTRY: United States
TITLE: Cytogenetics and molecular genetics of bladder cancer: a personal view.
PUBDATE: 20021001
The cytogenetic and molecular genetic aspects that may be involved in the pathogenesis of bladder cancer are presented. Although anomalies of chromosome 9 may play an initial causative role in this cancer, the subsequent events, involving a succession of genetic changes, are less established or understood. This presentation is a distillation of what generally are considered to be the cytogenetic and molecular genetic events that constitute the array of changes underlying bladder cancer.