0. DOCID:19251 SCORE: 0.00338890339894431
DOCNO: 2044145
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: V Zoubek V
AUTHOR: H Zoubková H
AUTHOR: M Mrůzek M
AFFILIATION: Interní oddĕlení nemocnice s poliklinikou, Krnov, primáŕ.
PUBTYPE: Journal Article
JOURNALTITLE: Casopís lékar̆ů c̆eských.
COUNTRY: CZECHOSLOVAKIA
TITLE: [The prevalence of idiopathic proctocolitis]
PUBDATE: 19910301
During screening of colorectal cancer by the Haemoccult test (Röhm Pharma Co.) the authors investigated the incidence of idiopathic proctocolitis in the population of the Bruntál district. The group of tested subjects comprises 16.642 of the population aged 45 to 86 years. After examination of 380 positive subjects (2.28%) twelve cases of idiopathic proctocolitis were detected. Of these twelve seven were identified previously and a new diagnosis was made in five subjects. At twelve cases were identified from a population of 16.642, the assumed prevalence in 1989 in the given age group is 72/100.000. This suggests considerable underestimation of the prevalence of idiopathic proctocolitis in current epidemiological surveys.

1. DOCID:17696 SCORE: 0.00303929780680593
DOCNO: 8363192
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
AUTHOR: F X Pi-Sunyer FX
AFFILIATION: St. Luke's-Roosevelt Hospital Center and Columbia University College of Physicians and Surgeons, New York, New York.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Annals of internal medicine.
COUNTRY: UNITED STATES
TITLE: Medical hazards of obesity.
PUBDATE: 19931001
The medical hazards of obesity are discussed. Risks include insulin resistance, diabetes mellitus, hypertriglyceridemia, decreased levels of high-density lipoprotein cholesterol, and increased levels of low-density lipoprotein cholesterol. Obesity is also associated with gallbladder disease and some forms of cancer as well as sleep apnea, chronic hypoxia and hypercapnia, and degenerative joint disease. Obesity is an independent risk factor for death from coronary heart disease. A central distribution of body fat enhances the risk for most of these conditions.

2. DOCID:17482 SCORE: 0.00288015197647473
DOCNO: 1914751
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: therapy
AUTHOR: M Kusunoki M
AUTHOR: S Fujita S
AUTHOR: Y Sakanoue Y
AUTHOR: Y Shoji Y
AUTHOR: H Yanagi H
AUTHOR: T Yamamura T
AUTHOR: J Utsunomiya J
AFFILIATION: Second Department of Surgery, Hyogo College of Medicine, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases.
PUBDATE: 19910901
Since 1980, when the first description of hyperplastic polyposis of the colon appeared, 18 cases of hyperplastic polyposis have been reported in the literature. Only two of them bore colonic cancer. Here we add two cases of hyperplastic polyposis accompanying rectal carcinoma following cancer resection, in which residual hyperplastic polyps disappeared after resection.

3. DOCID:17899 SCORE: 0.00281669679112088
DOCNO: 2249323
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: S Y Yang SY
AFFILIATION: Suihua Tuberculosis Control Centre, Zhaodong, Heilongjiang.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases.
COUNTRY: CHINA
TITLE: [A clinical study on 65 cases with tracheobronchial tuberculosis]
PUBDATE: 19900601
We recently diagnosed 65 cases with tracheobronchial tuberculosis using fiberbronchoscope. All the patients presented TB symptoms and were smear positive, some of them had been misdiagnosed for chronic bronchitis or lung cancer. Among them, 16 cases were simple tracheobronchial tuberculosis (24.6%) without TB lesions in the lungs. The results show that fiberbronchoscopic examination is a good method to diagnose tracheobronchial tuberculosis and distinguish lung cancer by direct observation of tracheobronchial lostons or brush biopsy for TB.

4. DOCID:23136 SCORE: 0.00276186518452937
DOCNO: 9050139
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Therapy
DESCRIPTOR: Gene Transfer Techniques
DESCRIPTOR: Genetic Vectors
QUALIFIER: methods
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: M G Sanda MG
AFFILIATION: Department of Urology, Ann Arbor Veterans Administration Medical Center, MI, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in urologic oncology.
COUNTRY: UNITED STATES
TITLE: Biological principles and clinical development of prostate cancer gene therapy.
PUBDATE: 19970201
Several clinical trials of prostate cancer gene therapy are underway. The therapeutic genes being evaluated by these and other, forthcoming, trials include immunogenes, cell death-inducing genes, antioncogenes, and tumor suppressor genes. Constraints of current gene transfer vectors limit, to local-regional targeting, those gene therapy strategies that do not rely on an intervening immune response. Preclinical models predict modest, if any, therapeutic effects with current forms of prostate cancer gene therapy. Using biological surrogate endpoints and applying further preclinical advances will allow clinical prostate cancer gene therapy to attain its full potential.

5. DOCID:22535 SCORE: 0.00272897341590551
DOCNO: 9143847
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Biopsy, Needle
DESCRIPTOR: Immunohistochemistry
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: analysis
AUTHOR: I S Quinodoz IS
AUTHOR: S D Berger SD
AUTHOR: P Schafer P
AUTHOR: S Remadi S
AFFILIATION: Division de Pathologie Clinique, Hôpital Cantonal Universitaire, Geneva, Switzerland.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Diagnostic cytopathology.
COUNTRY: UNITED STATES
TITLE: Adenoid cystic carcinoma of the breast: utility of immunocytochemical study with collagen IV on fine-needle aspiration.
PUBDATE: 19970501
A case of adenoid cystic carcinoma (ACC) of the breast in a 71-year-old woman is reported. This neoplasm accounts for about 0.1% of all breast cancers. The mammography showed a well-delineated mass without calcifications. Cytologic examination of percutaneous fine-needle aspiration (FNA) material gave the diagnostic of ACC, which was confirmed by histologic examination. This report emphasizes the utility of immunocytochemical study with collagen IV antibody on FNA material of this uncommon tumor.

6. DOCID:20652 SCORE: 0.00270582675543764
DOCNO: 8742094
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: drug therapy
AUTHOR: P L Dellemijn PL
AUTHOR: C J Vecht CJ
AFFILIATION: Department of Neurology, Sint Joseph, Ziekenhuis, The Netherlands.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Anti-cancer drugs.
COUNTRY: ENGLAND
TITLE: Towards better pain treatment in cancer.
PUBDATE: 19960101
This review focuses on ways to ameliorate diagnosis and treatment of cancer-related pain with currently available knowledge and methods. The first part indicates how to improve pain assessment and diagnosis in the cancer patient. The second part evaluates current views for adequate pain management based on evidence of double-blind analgesic trials in cancer-related pain and deals with misconceptions in established symptomatic therapy.

7. DOCID:23764 SCORE: 0.00270465348689421
DOCNO: 7735542
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Television
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: A Saito A
AUTHOR: N Yagi N
AUTHOR: K Miura K
AUTHOR: Y Takano Y
AFFILIATION: Section of Thoracic Surgery, Akita Red Cross Hospital, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Surgical laparoscopy & endoscopy.
COUNTRY: UNITED STATES
TITLE: Video-assisted right lower lobectomy for a lung cancer with mini-thoracotomy.
PUBDATE: 19950201
We report a case of T1N0M0 lung cancer in which we successfully performed video-assisted right lower lobectomy and mediastinal lymph node dissection. The lobectomy was done on a 64-year-old woman who had a 2-cm adenocarcinoma in the right lower lobe. The procedure could be done safely and adequately using three trocars and a 5-cm mini-thoracotomy. The patient had an uncomplicated postoperative course and was satisfied with minimal postoperative pain, quick recovery, and minute skin scars. Video-assisted lobectomy may be a reasonable approach in selected patients of primary lung carcinoma.

8. DOCID:17586 SCORE: 0.00266240501426861
DOCNO: 1408102
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: K Lapis K
AFFILIATION: I. sz. Pathologiai és Kísérleti Rákkutató Intézet, Semmelweis Orvostudományi Egyetem, Budapest.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Prognostic value of cell proliferation markers in malignant tumor diseases]
PUBDATE: 19921001
Novel methods used in studying the proliferation activity and cell kinetics of malignant neoplasms such as: the in vivo and in vitro bromodeoxyuridine labeling, the flow cytometric DNS analysis, the immunohistochemical demonstration of the so called proliferation associated antigens and the counting of nucleolar organized regions are briefly introduced. The data obtainable by these methods are reviewed and critically discussed. The prognostic value of the obtained data and their utility in planning and monitoring of cancer patients' therapy are also discussed.

9. DOCID:21670 SCORE: 0.00261510264755687
DOCNO: 9165503
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Clinical Trials, Phase III
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: R Gams R
AFFILIATION: Division of Hematology/Oncology Ohio State University, Columbus, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Phase III trials of toremifene vs tamoxifen.
PUBDATE: 19970501
Three pivotal phase III trials conducted in North America and Europe served as the basis for the application for approval of toremifene (Fareston) by the FDA. These trials demonstrated that 60 mg/d of toremifene is safe and effective in the treatment of advanced breast cancer in postmenopausal women. The studies also indicated that, on the basis of antitumor efficacy, as well as safety, toremifene is at least equivalent to tamoxifen and may have some long-term advantages.

10. DOCID:19152 SCORE: 0.00257416839679623
DOCNO: 1851377
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: P Kelly P
AUTHOR: A A O'Brien AA
AUTHOR: P Daly P
AUTHOR: L Clancy L
AFFILIATION: Peamount Hospital, Newcastle, Co. Dublin.
PUBTYPE: Journal Article
JOURNALTITLE: Age and ageing.
COUNTRY: ENGLAND
TITLE: Small-cell lung cancer in elderly patients: the case for chemotherapy.
PUBDATE: 19910101
We present a retrospective analysis of survival in 48 elderly (older than 65 years) and 70 young patients with small-cell lung cancer. Thirty-four elderly and 62 young patients had combination chemotherapy. Overall probability of survival with combination chemotherapy was similar for old and young patients (chi 2 = 0.79, d.f. = 1, p = 0.374). Peripheral neuropathy secondary to vincristine was more common with elderly patients. We believe that decisions about chemotherapy in elderly patients with small-cell lung cancer should be based on performance status, extent of disease and clinical condition rather than age.

11. DOCID:22525 SCORE: 0.00254503847941354
DOCNO: 9450419
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: history
QUALIFIER: history
AUTHOR: L LeMoine L
AFFILIATION: Dr. Everett Chalmers Hospital, Fredericton, N.B.
PUBTYPE: Biography
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: Canadian oncology nursing journal = Revue canadienne de nursing oncologique.
COUNTRY: CANADA
TITLE: Essiac: an historical perspective.
PUBDATE: 19971101
It is believed that over one-half of people diagnosed with cancer will at some point use an unconventional therapy (Hopkins & Brigden, 1991). In light of this, nurses have a professional responsibility to learn about unconventional therapies (Fletcher, 1992) so they can help their patients make informed choices. This article focuses on Essiac, an unconventional therapy that has historically and is presently being used by some cancer patients. While reasons patients might choose unconventional therapies are identified, the majority of this article focuses on the history of Essiac, where it stands today, and the need for sound scientific research.

12. DOCID:21276 SCORE: 0.0025359499871264
DOCNO: 8820870
AUTHOR: L S Jones LS
AFFILIATION: Dept of Developmental Biology and Anatomy, University of South Carolina School of Medicine, Columbia 29208, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Trends in neurosciences.
COUNTRY: ENGLAND
TITLE: Integrins: possible functions in the adult CNS.
PUBDATE: 19960201
Integrins comprise a large family of heterodimeric proteins that mediate cell-cell and cell-extracellular-matrix adhesive connections. There is an extensive literature on their importance in neural development and cancer, but evidence for the existence of integrins in the adult CNS has emerged only recently. With growing immunohistochemical and molecular biological evidence for the presence of integrins in the adult CNS, a variety of functions from microglial migration to synaptic rearrangements can be considered for these adhesive proteins.

13. DOCID:23947 SCORE: 0.00251065180573866
DOCNO: 8677399
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Clinical Trials
AUTHOR: J J Dignam JJ
AUTHOR: L A Weissfeld LA
AUTHOR: S J Anderson SJ
AFFILIATION: Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pa 15261, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Statistics in medicine.
COUNTRY: ENGLAND
TITLE: Methods for bounding the marginal survival distribution.
PUBDATE: 19950901
For time to event data with many potential failure types, one cannot uniquely determine the distribution of time to a specific event type, or marginal survival distribution, in the case where event types are mutually exclusive. In this paper we discuss several methods for estimating functions that bound the non-identifiable marginal survival distribution in the competing risks problem. We compute and compare bounds for data simulated from two bivariate survival distributions. Results show that the methods provide a suitable estimate of the marginal survival probability when one has specified dependence correctly. Data from a large clinical trial for breast cancer illustrate the methods.

14. DOCID:20736 SCORE: 0.00247055322703345
DOCNO: 7647308
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: physiology
QUALIFIER: etiology
AUTHOR: J Pines J
AFFILIATION: Wellcome/CRC Institute, Cambridge, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: UNITED STATES
TITLE: Cyclins, CDKs and cancer.
PUBDATE: 19950401
The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes. In this review I will attempt to show how perturbations in the known cell cycle regulators may play a part in the process of oncogenesis.