0. DOCID:19733 SCORE: 0.00440121869136981
DOCNO: 2405031
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: epidemiology
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: S Preston-Martin S
AUTHOR: S C White SC
AFFILIATION: University of Southern California School of Medicine, Los Angeles.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the American Dental Association (1939)
COUNTRY: UNITED STATES
TITLE: Brain and salivary gland tumors related to prior dental radiography: implications for current practice.
PUBDATE: 19900201
Five epidemiological studies of brain, cranial meninge, and salivary gland tumor sites reviewed implicate prior dental radiography with increased risk of subtentorial intracranial meningiomas and tumors of the parotid gland. Diagnostic radiography (medical and dental) was the most important risk factor identified for parotid gland cancers; among Los Angeles County residents, about 85% of the cumulative parotid dose from diagnostic radiography came from dental examinations. Irradiation of patients during dental radiography declined substantially from 1920 to 1988; it is uncertain whether current low doses increase risk. Recommendations for exposure reduction are made.


1. DOCID:17766 SCORE: 0.00371777515535781
DOCNO: 1758433
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: etiology
QUALIFIER: therapy
AUTHOR: J B Kelly JB
AUTHOR: R Payne R
AFFILIATION: Department of Neurology, University of Cincinnati College of Medicine, Ohio.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Neurologic clinics.
COUNTRY: UNITED STATES
TITLE: Pain syndromes in the cancer patient.
PUBDATE: 19911101
Paraneoplastic syndromes affect the nervous system in a very small percentage of patients with cancer. In those patients, portions of the nervous system are damaged or destroyed, usually in association with a small and often occult neoplasm elsewhere in the body. Current evidence suggests that these syndromes occur when the body mounts an immune response to an antigen shared between the tumor and the nervous system. The immune attack is then misdirected against that portion of the nervous system that possesses the "onconeural" antigen.


2. DOCID:18478 SCORE: 0.00326731294373221
DOCNO: 8468270
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mutagenesis
QUALIFIER: therapy
AUTHOR: K T Kelsey KT
AUTHOR: M Caggana-Aviles M
AUTHOR: P Mauch P
AUTHOR: C N Coleman CN
AUTHOR: L N Shulman LN
AUTHOR: H L Liber HL
AFFILIATION: Department of Cancer Biology, Harvard School of Public Health, Boston, Massachusetts.
PUBTYPE: Journal Article
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: ENGLAND
TITLE: Mutagenesis after therapy for Hodgkin's disease.
PUBDATE: 19930401
Therapy for Hodgkin's disease has been associated with a significant increase in risk for second cancers. To begin an investigation of the association of therapy-induced genetic damage with this risk, somatic mutations at the hypoxanthine phosphoribosyltransferase locus were measured in lymphocytes from patients previously treated for Hodgkin's disease. The results demonstrate that a subset of patients have persistently elevated mutation frequencies, perhaps suggesting that these individuals are among those at significant risk of second cancer development.


3. DOCID:18989 SCORE: 0.0032386371702793
DOCNO: 2165207
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: S D Swanson SD
AUTHOR: L E Quint LE
AUTHOR: H N Yeung HN
AFFILIATION: Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109.
PUBTYPE: Journal Article
JOURNALTITLE: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine.
COUNTRY: UNITED STATES
TITLE: Proton-enhanced 13C imaging/spectroscopy by polarization transfer.
PUBDATE: 19900701
Carbon-13 magnetic resonance imaging/spectroscopy (CMRI/S) was performed using polarization transfer techniques where sensitivity of the carbon signal was enhanced by transferring the proton spin order to the carbon nuclei. The experimental feasibility of using polarization transfer techniques at 2.0 T was demonstrated with a phantom and an intact chicken egg. The potential clinical applications of CMRI/S with polarization transfer include the assessment of prostate cancer. Preliminary results using human prostate specimens are presented.


4. DOCID:19036 SCORE: 0.00316308189185266
DOCNO: 1633928
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: physiology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: K Matsumoto K
AFFILIATION: Osaka Medical Center for Maternal and Child Health.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon Naibunpi Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Hormones and growth of cancer]
PUBDATE: 19920601
Estrogen and androgen play essential roles in the development of breast cancer and prostate cancer, respectively. However, only 30% of breast cancer mass and 70% of prostate cancer mass are found to be hormone-dependent when they have been treated clinically. These findings show that hormone dependency of cancer disappears rather easily. Recently, it has been found that the growth of hormone-dependent cancer is mediated through sex steroid-induced growth factors in an autocrine manner. Future studies on sex steroid-induced growth factor(s) will play important roles in order to understand the molecular mechanisms of the development and growth of breast cancer and prostate cancer.


5. DOCID:16600 SCORE: 0.00307964977785058
DOCNO: 2259278
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: radiotherapy
AUTHOR: G A Ushakova GA
AUTHOR: B P Afanas'ev BP
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [The optimization of the dosimetric plan in the intracavity radiotherapy of patients with cancer of the corpus uteri]
PUBDATE: 19901101
The potentialities of mathematical optimization were investigated with respect to dosimetric design of radiation therapy of endometrial cancer patients using AGAT-V and AGAT-VU [correction of Agat-B and Agat-Y] apparatus. The effectiveness of linear programming for creating in a pathological focus and in normal tissues of a dose distribution, meeting clinical requirements to the maximum, was shown.


6. DOCID:19638 SCORE: 0.0029423335280052
DOCNO: 2318454
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: M Brodman M
AUTHOR: F Friedman F
AUTHOR: P Dottino P
AUTHOR: C Janus C
AUTHOR: S Plaxe S
AUTHOR: C Cohen C
AFFILIATION: Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, New York 10029.
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: A comparative study of computerized tomography, magnetic resonance imaging, and clinical staging for the detection of early cervix cancer.
PUBDATE: 19900301
Sixteen patients with cervical cancer underwent radical surgery following standard clinical staging, MRI, and CT. The sensitivity of the CT scan was 14%, the specificity 100%. MRI had a sensitivity of 28% and a specificity of 64%. The clinical stage was correct in 10 of 16 patients (62%). CT and MRI are not individually or collectively better than clinical staging in predicting extent of disease, and currently should not be included in the FIGO staging for cervix cancer.


7. DOCID:18259 SCORE: 0.00284540686688468
DOCNO: 15463632
OWNER: NLM
STATUS: PubMed-not-MEDLINE
AUTHOR: B Maresca B
AUTHOR: L Carratù L
AFFILIATION: International Institute of Genetics and Biophysics, CNR, Via Marconi 12, 80125 Naples, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Parasitology today (Personal ed.)
COUNTRY: England
TITLE: The biology of the heat shock response in parasites.
PUBDATE: 19920801
The heat shock response is a general homeostatic mechanism that protects cells and the entire organism from the deleterious effects of environmental stress. It has been shown that heat shock proteins play major roles in many cellular processes and have a unique role in several areas of cell biology, from chronic degenerative diseases to immunology and from cancer research to interactions between host and parasite. In this review, Bruno Maresca and Luisella Carratu deal with some of the unique characteristics of the heat shock response in parasitic organisms.


8. DOCID:18130 SCORE: 0.00281435920467454
DOCNO: 1544095
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: organization & administration
AUTHOR: R E Bird RE
AFFILIATION: Center for Breast Diagnosis, Charlotte, North Carolina 28203.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: A successful breast cancer screening program.
PUBDATE: 19920401
A private, low-cost mammography screening program in Charlotte, North Carolina, has grown from one to four fixed sites in the past 6 years and now screens more than 25,000 women annually. An ongoing medical audit of the program shows that the percentage of patients with breast cancer with positive lymph nodes has decreased from 29% to 13%, and the percentage of minimal cancers found has increased from 31% to 52%. Compliance for regular screening has remained at approximately 50% for the past 2 years. Means of increasing compliance to desired levels are discussed.


9. DOCID:19816 SCORE: 0.0027001715262531
DOCNO: 1834151
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapeutic use
QUALIFIER: complications
AUTHOR: J P Doweiko JP
AUTHOR: M A Goldberg MA
AFFILIATION: Department of Medicine, Brigham and Women's Hospital, Harvard Medical School.
PUBTYPE: Journal Article
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Erythropoietin therapy in cancer patients.
PUBDATE: 19910801
The majority of patients with cancer become anemic during the course of their disease. This anemia appears to be due largely to a blunted erythropoietin (Epo) response and an impaired ability of the bone marrow to respond to endogenous Epo. Both are exacerbated by chemotherapy and radiation therapy. Recombinant human erythropoietin (rhEpo) ameliorates the anemia associated with malignancy. However, we do not yet know whether rhEpo will decrease the need for homologous blood transfusions and improve the quality of life of cancer patients. While rhEpo will greatly alter the treatment of anemia in the 1990s, its precise role in the treatment of oncology patients is still being elucidated.


10. DOCID:19004 SCORE: 0.00268208621720636
DOCNO: 2228010
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: pathology
AUTHOR: A K Khanna AK
AUTHOR: S K Saxena SK
AUTHOR: S Khanna S
AUTHOR: A Kumar A
AFFILIATION: Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India.
PUBTYPE: Journal Article
JOURNALTITLE: Indian journal of cancer.
COUNTRY: INDIA
TITLE: Histopathological changes following anterior chemotherapy in advanced breast cancer.
PUBDATE: 19900601
Twenty five patients of advanced breast cancer (Stage IIIb and IV) were studied and the histological changes following chemotherapy were looked. All the tumours showed varying degree of histological changes. Twenty eight percent tumours showed Grade I changes, 28 percent had Grade II changes and 28 percent had Grade III changes. Residual tumour was present in all the cases. The tumour showing higher grade of cancer cell degeneration following chemotherapy had better response. Seven tumours showing Grade III changes had 85.7 percent partial response. No complete response was achieved.


11. DOCID:18990 SCORE: 0.00268204219361105
DOCNO: 2371646
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: diagnosis
AUTHOR: L M Ellis LM
AUTHOR: K I Bland KI
AFFILIATION: Department of Surgery, University of Florida College of Medicine, Gainesville.
PUBTYPE: Journal Article
JOURNALTITLE: The Surgical clinics of North America.
COUNTRY: UNITED STATES
TITLE: Techniques for obtaining the diagnosis of malignant breast lesions.
PUBDATE: 19900801
Although fine needle aspiration is an efficacious method for diagnosing the palpable breast cancer, a negative aspirate does not exclude the presence of a malignancy. Open breast biopsy remains the standard of care in diagnosing a malignant breast lesion. All breast biopsies should be planned as if the scar were to be excised by a definitive surgical procedure (either mastectomy or tylectomy). New lesions in the treated breast require immediate biopsy because of the high likelihood of recurrent disease. Preferably, definitive surgery for malignancy should not be delayed more than 2 weeks after biopsy.


12. DOCID:17901 SCORE: 0.00257628085575875
DOCNO: 2214156
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: M Yakushiji M
AFFILIATION: Dept. of Genecol. & Obstet., Krume Univ. School of Med.
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Surgical treatment of ovarian cancer]
PUBDATE: 19900801
Stage I a cancer among early ovarian cancers should be classified because of revision of FIGO classification in 1987, therefore preservation of fertility has become expected to date. Furthermore, a maximal debulking surgery as an initial operation, compared to a staging laparotomy, has yielded favorable results in the clinical outcome of advanced ovarian cancers in recent years. Surgical treatment will still make a major role in the future as one of the multiple therapeutic modalities in this disease, although a complete cure can not be obtained by only surgical treatment.


13. DOCID:19204 SCORE: 0.00249430079548301
DOCNO: 8479212
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: P L Whitesell PL
AUTHOR: S G Peters SG
AFFILIATION: Division of Thoracic Diseases and Internal Medicine, Mayo Clinic Rochester, Minnesota.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Mayo Clinic proceedings. Mayo Clinic.
COUNTRY: UNITED STATES
TITLE: Pulmonary manifestations of extrathoracic malignant lesions.
PUBDATE: 19930501
Two of the most common thoracic manifestations of extrapulmonary malignant tumors are thoracic metastatic lesions and pulmonary thromboembolism. Recognition of the broad array of patterns of pulmonary metastatic involvement is essential for optimal management of oncology patients. In addition to the "typical" pattern of multiple bilateral nodules, patients may have solitary nodules, reticulonodular infiltrates, hilar and mediastinal adenopathy, endobronchial obstruction, pleural disease, or even normal roentgenographic findings. An awareness of the association between cancer and pulmonary thromboembolism is also valuable. The mechanisms potentially responsible for the thrombotic events associated with malignant disease are discussed, and diagnostic issues are reviewed.


14. DOCID:17190 SCORE: 0.00245044322990638
DOCNO: 2282862
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pharmacology
AUTHOR: S M Lu SM
AFFILIATION: Affiliated Obstetrics and Gynecology Hospital, Zhejiang Medical University, Hangzhou.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua fu chan ke za zhi.
COUNTRY: CHINA
TITLE: [In vitro drug-resistance decrease of ovarian cancer cells]
PUBDATE: 19901101
A chemosensitivity test for ovarian cancer using tritiated thymidine incorporation assay was carried out. A dose-response relationship was observed for cis-platinum and an 5-fold increase of concentration converted the drug resistant tumor into a drug-sensitive one. Verapamil was found to enhance the cytotoxic effect of vincristine against ovarian cancer cells. It is suggested that combination of vincristine with verapamil may be helpful in treating some vincristine-resistant cases.