0. DOCID:30439 SCORE: 0.00508556874274074
DOCNO: 12117193
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: Susan M Ascher SM
AUTHOR: Caroline Reinhold C
AFFILIATION: Department of Radiology, Georgetown University Hospital, Washington, DC 20007-2197, USA. aschers@gunet.georgetown.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiologic clinics of North America.
COUNTRY: United States
TITLE: Imaging of cancer of the endometrium.
PUBDATE: 20020501
Transvaginal US is often the initial imaging examination for women with dysfunctional (postmenopausal or intermenstrual) uterine bleeding. However, once the diagnosis of endometrial cancer has been made, contrast-enhanced MRI should be performed in patients who require multifactorial assessment (eg, depth of myometrial invasion, cervical involvement, lymph node metastasis). The results of contrast-enhanced MRI help distinguish patients who need more aggressive therapy and referral to a gynecologic oncologist from those who will do well treated by a community gynecologist.

1. DOCID:19733 SCORE: 0.00440121869136981
DOCNO: 2405031
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: epidemiology
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: S Preston-Martin S
AUTHOR: S C White SC
AFFILIATION: University of Southern California School of Medicine, Los Angeles.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the American Dental Association (1939)
COUNTRY: UNITED STATES
TITLE: Brain and salivary gland tumors related to prior dental radiography: implications for current practice.
PUBDATE: 19900201
Five epidemiological studies of brain, cranial meninge, and salivary gland tumor sites reviewed implicate prior dental radiography with increased risk of subtentorial intracranial meningiomas and tumors of the parotid gland. Diagnostic radiography (medical and dental) was the most important risk factor identified for parotid gland cancers; among Los Angeles County residents, about 85% of the cumulative parotid dose from diagnostic radiography came from dental examinations. Irradiation of patients during dental radiography declined substantially from 1920 to 1988; it is uncertain whether current low doses increase risk. Recommendations for exposure reduction are made.

2. DOCID:17766 SCORE: 0.00371777515535781
DOCNO: 1758433
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: etiology
QUALIFIER: therapy
AUTHOR: J B Kelly JB
AUTHOR: R Payne R
AFFILIATION: Department of Neurology, University of Cincinnati College of Medicine, Ohio.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Neurologic clinics.
COUNTRY: UNITED STATES
TITLE: Pain syndromes in the cancer patient.
PUBDATE: 19911101
Paraneoplastic syndromes affect the nervous system in a very small percentage of patients with cancer. In those patients, portions of the nervous system are damaged or destroyed, usually in association with a small and often occult neoplasm elsewhere in the body. Current evidence suggests that these syndromes occur when the body mounts an immune response to an antigen shared between the tumor and the nervous system. The immune attack is then misdirected against that portion of the nervous system that possesses the "onconeural" antigen.

3. DOCID:31684 SCORE: 0.00347501870498315
DOCNO: 12735680
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemical synthesis
QUALIFIER: pharmacology
QUALIFIER: chemical synthesis
QUALIFIER: chemical synthesis
QUALIFIER: pharmacology
AUTHOR: Sang Kook Lee SK
AUTHOR: Kyung Ae Nam KA
AUTHOR: Yeon Hoi Hoe YH
AUTHOR: Hye-Young Min HY
AUTHOR: Eun-Young Kim EY
AUTHOR: Hyojin Ko H
AUTHOR: Soyoung Song S
AUTHOR: Taeho Lee T
AUTHOR: Sanghee Kim S
AFFILIATION: College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, Seoul 120-750, Korea. sklee@ewha.ac.kr
PUBTYPE: Journal Article
JOURNALTITLE: Archives of pharmacal research.
COUNTRY: Korea (South)
TITLE: Synthesis and evaluation of cytotoxicity of stilbene analogues.
PUBDATE: 20030401
Resveratrol analogs were newly synthesized and evaluated for cytotoxicity in cultured human lung and colon cancer cells. 3,5,4-Trimethoxy-trans-stilbene and 3,5,2',4'-tetramethoxy-trans-stilbene were found to be more potent rather than resveratrol. 3,4,5-Trimethoxy-4'-bromo-cis-stilbene was the most active among the test compounds.

4. DOCID:25519 SCORE: 0.00345466236987213
DOCNO: 11394005
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Liver Transplantation
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: surgery
AUTHOR: K Urata K
AUTHOR: S Kawasaki S
AFFILIATION: First Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Geka Gakkai zasshi.
COUNTRY: Japan
TITLE: [Liver transplantation for liver metastases of colorectal cancer]
PUBDATE: 20010501
Because of the critical shortage of donor organs, liver transplantation for metastatic tumors should be reserved for patients in whom long-term survival is possible. Transplantation in patients with metastatic tumors from colorectal cancer has resulted only in short disease-free intervals, and palliation was achieved in only a few patients. In patients with symptomatic neuroendocrine tumors unresponsive to conventional therapy, on the other hand, reasonably good disease-free intervals and prolonged survival may justify liver transplantation.

5. DOCID:22745 SCORE: 0.00338646378574755
DOCNO: 7724852
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Glass
QUALIFIER: trends
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Regulatory toxicology and pharmacology : RTP.
COUNTRY: UNITED STATES
TITLE: Postscript: science and public policy on synthetic vitreous fibers.
PUBDATE: 19941201
Rapid advances are being made in our understanding of the interaction of airborne fibers with biological tissues. It is possible to reduce human exposures and potential risk to lung cancer and fibrosis if current science and models are fully utilized. However, the criteria used by IARC and NTP in their cancer classifications have not kept pace with current science and, in fact, remain entrenched in the scientific vagaries present in the 1960's. As long as public policy cannot keep pace with contemporary scientific understanding, we are doomed to a world of exaggerated risks, inappropriate regulations, misguided priorities, inadequate funding for social and environmental programs, mass anxiety, and skepticism about scientific research.

6. DOCID:27943 SCORE: 0.00331663026016405
DOCNO: 10559547
AUTHOR: D W Lamson DW
AUTHOR: M S Brignall MS
AFFILIATION: Tahoma Clinic, Kent, WA, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Alternative medicine review : a journal of clinical therapeutic.
COUNTRY: UNITED STATES
TITLE: Antioxidants in cancer therapy; their actions and interactions with oncologic therapies.
PUBDATE: 19991001
There is a concern that antioxidants might reduce oxidizing free radicals created by radiotherapy and some forms of chemotherapy, and thereby decrease the effectiveness of the therapy. The question has arisen whether concurrent administration of oral antioxidants is contraindicated during cancer therapeutics. Evidence reviewed here demonstrates exogenous antioxidants alone produce beneficial effects in various cancers, and except for a few specific cases, animal and human studies demonstrate no reduction of efficacy of chemotherapy or radiation when given with antioxidants. In fact, considerable data exists showing increased effectiveness of many cancer therapeutic agents, as well as a decrease in adverse effects, when given concurrently with antioxidants.

7. DOCID:18478 SCORE: 0.00326731294373221
DOCNO: 8468270
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mutagenesis
QUALIFIER: therapy
AUTHOR: K T Kelsey KT
AUTHOR: M Caggana-Aviles M
AUTHOR: P Mauch P
AUTHOR: C N Coleman CN
AUTHOR: L N Shulman LN
AUTHOR: H L Liber HL
AFFILIATION: Department of Cancer Biology, Harvard School of Public Health, Boston, Massachusetts.
PUBTYPE: Journal Article
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: ENGLAND
TITLE: Mutagenesis after therapy for Hodgkin's disease.
PUBDATE: 19930401
Therapy for Hodgkin's disease has been associated with a significant increase in risk for second cancers. To begin an investigation of the association of therapy-induced genetic damage with this risk, somatic mutations at the hypoxanthine phosphoribosyltransferase locus were measured in lymphocytes from patients previously treated for Hodgkin's disease. The results demonstrate that a subset of patients have persistently elevated mutation frequencies, perhaps suggesting that these individuals are among those at significant risk of second cancer development.

8. DOCID:23745 SCORE: 0.00326462499017414
DOCNO: 8630975
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cell Cycle
DESCRIPTOR: Chromosome Fragility
QUALIFIER: ultrastructure
QUALIFIER: genetics
AUTHOR: N Capalash N
AUTHOR: R C Sobti RC
AFFILIATION: Center for Biotechnology, Panjab University, Chandigarh, India.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Spontaneous genomic fragility and cell cycle progression in lymphocytes of patients with cervical carcinoma.
PUBDATE: 19960501
Thirty patients with invasive carcinoma of the cervix, along with 15 age-matched healthy females as controls, were studied to examine the frequency of spontaneous SCEs, chromosomal aberrations (CAs), and cell cycle progression in lymphocytes. The frequency of SCEs and TCAs was statistically significant in the patients over the control group. The correlation of SCEs and TCAs with the stage of cancer, age, and number of pregnancies was also made. The cell cycle of lymphocytes showed its prolongation in the patients, as is evident from the higher proportion of cells at M1 (metaphase of first cell division after 72 hours).

9. DOCID:18989 SCORE: 0.0032386371702793
DOCNO: 2165207
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: S D Swanson SD
AUTHOR: L E Quint LE
AUTHOR: H N Yeung HN
AFFILIATION: Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109.
PUBTYPE: Journal Article
JOURNALTITLE: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine.
COUNTRY: UNITED STATES
TITLE: Proton-enhanced 13C imaging/spectroscopy by polarization transfer.
PUBDATE: 19900701
Carbon-13 magnetic resonance imaging/spectroscopy (CMRI/S) was performed using polarization transfer techniques where sensitivity of the carbon signal was enhanced by transferring the proton spin order to the carbon nuclei. The experimental feasibility of using polarization transfer techniques at 2.0 T was demonstrated with a phantom and an intact chicken egg. The potential clinical applications of CMRI/S with polarization transfer include the assessment of prostate cancer. Preliminary results using human prostate specimens are presented.

10. DOCID:19036 SCORE: 0.00316308189185266
DOCNO: 1633928
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: physiology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: K Matsumoto K
AFFILIATION: Osaka Medical Center for Maternal and Child Health.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon Naibunpi Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Hormones and growth of cancer]
PUBDATE: 19920601
Estrogen and androgen play essential roles in the development of breast cancer and prostate cancer, respectively. However, only 30% of breast cancer mass and 70% of prostate cancer mass are found to be hormone-dependent when they have been treated clinically. These findings show that hormone dependency of cancer disappears rather easily. Recently, it has been found that the growth of hormone-dependent cancer is mediated through sex steroid-induced growth factors in an autocrine manner. Future studies on sex steroid-induced growth factor(s) will play important roles in order to understand the molecular mechanisms of the development and growth of breast cancer and prostate cancer.

11. DOCID:21951 SCORE: 0.00313002314200156
DOCNO: 8542243
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: V K Hamasaki VK
AUTHOR: E E Vokes EE
AFFILIATION: Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Medical oncology (Northwood, London, England)
COUNTRY: ENGLAND
TITLE: Interferons and other cytokines in head and neck cancer.
PUBDATE: 19950301
The use of cytokines in head and neck cancer is increasingly under investigation. Clinical trials have tested the interferons, interleukin-2 and other cytokines as single agents and in various combinations. The addition of interferon to the cisplatin and 5-fluorouracil (5-FU) regimens (with and without leucovorin) has been explored. A randomized international trial comparing cisplatin and 5-FU with cisplatin, 5-FU and interferon-alpha 2b is in progress.

12. DOCID:16600 SCORE: 0.00307964977785058
DOCNO: 2259278
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: radiotherapy
AUTHOR: G A Ushakova GA
AUTHOR: B P Afanas'ev BP
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [The optimization of the dosimetric plan in the intracavity radiotherapy of patients with cancer of the corpus uteri]
PUBDATE: 19901101
The potentialities of mathematical optimization were investigated with respect to dosimetric design of radiation therapy of endometrial cancer patients using AGAT-V and AGAT-VU [correction of Agat-B and Agat-Y] apparatus. The effectiveness of linear programming for creating in a pathological focus and in normal tissues of a dose distribution, meeting clinical requirements to the maximum, was shown.

13. DOCID:31428 SCORE: 0.00295415418466382
DOCNO: 12676579
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: Gillian Payne G
AFFILIATION: ImmunoGen Inc, 128 Sidney Street, Cambridge, MA 02139, USA. gillian.payne@immunogen.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer cell.
COUNTRY: United States
TITLE: Progress in immunoconjugate cancer therapeutics.
PUBDATE: 20030301
Advances in immunoconjugate technology have revitalized the "magic bullet" concept of immunotherapeutics for the treatment of cancer. The growing availability of "human" antibodies, the increased epitope repertoire due to genomics and proteomics efforts, and advances in the means of identification and production of tumor-specific antibodies have greatly increased the potential for cancer therapeutic opportunities. Furthermore, the realization that effector molecule potency must be sufficiently high to be effective at concentrations that might realistically be delivered to the tumor site on an antibody carrier has greatly spurred the fields of medicinal chemistry and radionuclide chelate chemistry to produce such molecules.

14. DOCID:23941 SCORE: 0.00294485998253548
DOCNO: 8834313
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: metabolism
AUTHOR: S Masood S
AFFILIATION: Department of Pathology, University of Florida Health Science Center/Jacksonville 32209, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Diagnostic cytopathology.
COUNTRY: UNITED STATES
TITLE: Prognostic factors in breast cancer: use of cytologic preparations.
PUBDATE: 19951201
There is increasing evidence that certain morphological features and biological markers found in breast tumors may provide prognostic information by predicting the risk of recurrence and metastasis in early breast cancer. This information may also be important in choosing therapeutic options in patients with advanced disease. Prognostic testing is commonly performed on surgically excised lesions. However, there are clinical conditions in which a surgical specimen may not be suitable or available for such analysis. In these circumstances, fine-needle aspiration biopsy and imprint preparation provide an attractive sample for prognostic testings. This review summarizes the current approach to the use of cytologic preparation for assessment of established and newly recognized prognostic factors.