0. DOCID:31947 SCORE: 0.00285880782073024
DOCNO: 12073121
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Buttocks
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: pathology
AUTHOR: Ik Yang I
AUTHOR: Curtis W Hayes CW
AUTHOR: J Sybil Biermann JS
AFFILIATION: Department of Radiology, University of Michigan Health Systems, Ann Arbor, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Skeletal radiology.
COUNTRY: Germany
TITLE: Calcific tendinitis of the gluteus medius tendon with bone marrow edema mimicking metastatic disease.
PUBDATE: 20020601
A case of calcific tendinitis of the gluteus medius is presented. This report describes a patient with a history of breast cancer who had the combination of amorphous calcifications in the gluteus medius tendon and the MR finding of conspicuous bone marrow edema in the adjacent greater trochanter, prompting concern for metastatic disease. We present images from radiography, bone scanning, CT, and MR imaging. The unusual combination of findings in these studies should be considered conclusive for calcific tendinitis, and should not be confused with malignancy.


1. DOCID:31598 SCORE: 0.00230998348135791
DOCNO: 16382037
OWNER: NLM
STATUS: In-Process
AUTHOR: Patrick A Everley PA
AUTHOR: Bruce R Zetter BR
AFFILIATION: Department of Surgery, Children's Hospital / Harvard Medical School, Boston, Massachusetts 02115, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the New York Academy of Sciences.
COUNTRY: United States
TITLE: Proteomics in tumor progression and metastasis.
PUBDATE: 20051101
With the ultimate goal of systematically identifying and characterizing proteins within an organism, the field of proteomics has generated much excitement in the past few years. Coupled with mass spectrometry, various quantitative and functional techniques are now available that allow for large-scale analyses of proteins implicated in cancer. New techniques are just now being applied to identifying the temporal changes in protein levels associated with tumor development. This review will focus on the use and promise of proteomic technologies as they apply to the study of tumor progression and metastasis.


2. DOCID:31506 SCORE: 0.00230998238944532
DOCNO: 15756269
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: microbiology
QUALIFIER: complications
QUALIFIER: pathogenicity
QUALIFIER: epidemiology
QUALIFIER: microbiology
AUTHOR: A Shin A
AUTHOR: H R Shin HR
AUTHOR: D Kang D
AUTHOR: S K Park SK
AUTHOR: C-S Kim CS
AUTHOR: K-Y Yoo KY
AFFILIATION: Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Republic of Korea.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: England
TITLE: A nested case-control study of the association of Helicobacter pylori infection with gastric adenocarcinoma in Korea.
PUBDATE: 20050401
In a nested case-control study of 86 cases of gastric adenocarcinoma in relation to Helicobacter pylori infection in the Korean Multi-center Cancer Cohort, the H. pylori IgG seropositivity was 83.7% and that of the 344 matched controls was 80.8%, with a matched odds ratio for H. pylori infection of 1.06 (95% CI, 0.80-1.40).


3. DOCID:30061 SCORE: 0.00229990369396913
DOCNO: 15191008
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: therapeutic use
QUALIFIER: analogs & derivatives
QUALIFIER: drug therapy
QUALIFIER: virology
QUALIFIER: drug therapy
QUALIFIER: virology
QUALIFIER: chemically induced
AUTHOR: M E Melisko ME
AUTHOR: R Fox R
AUTHOR: A Venook A
AFFILIATION: Comprehensive Cancer Center, University of California, San Francisco, California 94115, USA. mmelisko@medicine.ucsf.edu
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical oncology (Royal College of Radiologists (Great Britain))
COUNTRY: England
TITLE: Reactivation of hepatitis C virus after chemotherapy for colon cancer.
PUBDATE: 20040501
Hepatitis C virus (HCV) infection often goes undiagnosed in asymptomatic carriers, but may become clinically relevant during periods of immunosuppression or severe illness. We report the clinical course of HCV reactivation in a patient receiving chemotherapy for metastatic colon cancer. We also review other reports showing the significance of HCV infection in patients being treated with chemotherapy.


4. DOCID:29982 SCORE: 0.00198764060672833
DOCNO: 14764990
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: biosynthesis
AUTHOR: Arun Singh A
AUTHOR: William D Figg WD
AFFILIATION: Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer biology & therapy.
COUNTRY: United States
TITLE: Upregulation of the androgen receptor during prostate cancer progression.
PUBDATE: 20040301
The androgen receptor is one of the central factors in mediating prostate cancer progression and is an important target for treatment. Several possible mechanisms have been put forth as to how it promotes this process. In the January 2004 issue of Nature Medicine, Chen et al. report that the androgen receptor is consistently upregulated as hormone sensitive prostate cancer changes to a hormone refractory state. They also show that this change is intricately involved during the development of resistance to androgen ablation therapy.


5. DOCID:29265 SCORE: 0.00182235421693348
DOCNO: 12360192
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: Gary Thomas G
AFFILIATION: Vollum Institute, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA. thomasg@ohsu.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature reviews. Molecular cell biology.
COUNTRY: England
TITLE: Furin at the cutting edge: from protein traffic to embryogenesis and disease.
PUBDATE: 20021001
Furin catalyses a simple biochemical reaction--the proteolytic maturation of proprotein substrates in the secretory pathway. But the simplicity of this reaction belies furin's broad and important roles in homeostasis, as well as in diseases ranging from Alzheimer's disease and cancer to anthrax and Ebola fever. This review summarizes various features of furin--its structural and enzymatic properties, intracellular localization, trafficking, substrates, and roles in vivo.


6. DOCID:31524 SCORE: 0.0017144220738233
DOCNO: 15150596
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: mortality
QUALIFIER: surgery
QUALIFIER: analysis
AUTHOR: K Canna K
AUTHOR: D C McMillan DC
AUTHOR: R F McKee RF
AUTHOR: A-M McNicol AM
AUTHOR: P G Horgan PG
AUTHOR: C S McArdle CS
AFFILIATION: University Department of Surgery, Glasgow Royal Infirmary, Alexandra Parade, Glasgow G31 2ER, Scotland, UK.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: England
TITLE: Evaluation of a cumulative prognostic score based on the systemic inflammatory response in patients undergoing potentially curative surgery for colorectal cancer.
PUBDATE: 20040501
The value of combining Dukes' stage and C-reactive protein to form a cumulative prognostic score was assessed in 147 patients undergoing potentially curative resection for colorectal cancer. The cancer-specific survival rates at 3 years for patients with a cumulative prognostic score of 0, 1 and 2 were 100, 77 and 40%, respectively (HR 4.76, 2.78-8.15, P<0.001).


7. DOCID:31247 SCORE: 0.0015801598753532
DOCNO: 16018609
OWNER: NLM
STATUS: In-Process
AUTHOR: John M Wiseman JM
AUTHOR: Frank E McDonald FE
AUTHOR: Dennis C Liotta DC
AFFILIATION: Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Organic letters.
COUNTRY: United States
TITLE: 1-Deoxy-5-hydroxysphingolipids as new anticancer principles: an efficient procedure for stereoselective syntheses of 2-amino-3,5-diols.
PUBDATE: 20050701
[reaction: see text]. Enantioselective preparation of the linear homoallylic alcohol I allows efficient formation of the 2-amino-3,5-diol moiety present in several biologically active compounds, including 1-deoxy-5-hydroxysphingosine analogue IV, which has exhibited excellent biological activity against colon cancer. The conversion of I into IV involves a sequence of enantioselective epoxidation of the O-tert-butoxycarbonyl derivative of I, followed by regioselective and stereospecific oxacyclization of II to introduce differentiated oxygens in III.


8. DOCID:30811 SCORE: 0.00155750687103895
DOCNO: 16001997
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Electrocoagulation
QUALIFIER: surgery
QUALIFIER: pathology
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: Mark B Fisher MB
AUTHOR: Andrew J Weise AJ
AUTHOR: Issac J Powell IJ
AFFILIATION: Department of Urology, Wayne State University, Detroit, MI 48201, USA. markbfisher@yahoo.com
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical breast cancer.
COUNTRY: United States
TITLE: Breast carcinoma metastatic to the bladder and renal pelvis requiring fulguration.
PUBDATE: 20050601
Breast cancer metastatic to the bladder has rarely been reported in the literature. A patient presented to our institution with pathologically confirmed breast cancer metastatic to the bladder with renal pelvis involvement as seen on retrograde pyelography. We believe cystoscopy with biopsy and fulguration to be the treatment of choice for breast cancer that has metastasized to the bladder because of the low rate of survival in patients with hematuria related to metastatic breast cancer.


9. DOCID:28638 SCORE: 0.00153845797668489
DOCNO: 15984515
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: analogs & derivatives
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
AUTHOR: Shunichi Negoro S
AFFILIATION: Dept. of Thoracic Oncology, Hyogo Medical Center for Adults, Akashi City, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Treatment of small cell lung cancer]
PUBDATE: 20050601
The treatment of choice for limited small-cell lung cancer (SCLC) is platinum-based chemotherapy combined with early, concurrent thoracic radiotherapy with a hyperfractionated regimen. The standard chemotherapy for extensive SCLC in Japan is the combination of irinotecan and cisplatin. There are expectations for new and effective molecular-target-based drugs for SCLC.


10. DOCID:30145 SCORE: 0.00146638158994252
DOCNO: 16226700
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Epigenesis, Genetic
QUALIFIER: genetics
AUTHOR: Andrew P Feinberg AP
AFFILIATION: Department of Medicine, Johns Hopkins University School of Medicine, 1064 Ross, Baltimore, MD 21205, USA. afeinberg@jhu.edu
PUBTYPE: Journal Article
JOURNALTITLE: Cancer cell.
COUNTRY: United States
TITLE: Cancer epigenetics is no Mickey Mouse.
PUBDATE: 20051001
Epigenetic changes are the most common alterations in human cancer, but it has been difficult to sort out cause and effect from studies of human tumors. Several recent nonlethal mouse models implicate both hypomethylation and loss of imprinting (LOI) in tumor formation, including a paper in this issue of Cancer Cell showing that transient hypomethylation in ES cells causes LOI and liver and intestinal tumors (). Hypomethylation appears to be a critical determinant of cancer, affecting chromosomal stability and specific gene targets.


11. DOCID:28699 SCORE: 0.00146069521358302
DOCNO: 12078917
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: prevention & control
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: metabolism
AUTHOR: Noel W Solomons NW
AFFILIATION: CeSSIAM-in-Guatemala, Guatemala City.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nutrition reviews.
COUNTRY: United States
TITLE: Nature's perfect food revisited: recent insights on milk consumption and chronic disease risk.
PUBDATE: 20020601
In Swedish volunteers, consuming spaghetti along with milk raises the insulinemic effect of the meal. In Finnish citizens followed for 19 to 24 years for cancer incidence, different consumption patterns of dairy items had different relationships with colon and rectal carcinogenesis. More definitive and conclusive research into how dairy products might influence chronic disease would seem to be warranted.


12. DOCID:30431 SCORE: 0.00146068995898979
DOCNO: 12392103
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: pharmacology
QUALIFIER: chemistry
AUTHOR: Makoto Watanabe M
AUTHOR: Sumio Hayakawa S
AUTHOR: Mamoru Isemura M
AUTHOR: Shigenori Kumazawa S
AUTHOR: Tsutomu Nakayama T
AUTHOR: Chihiro Mori C
AUTHOR: Toshioki Kawakami T
AFFILIATION: School of Food and Nutritional Sciences, University of Shizuoka, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Biological & pharmaceutical bulletin.
COUNTRY: Japan
TITLE: Identification of licocoumarone as an apoptosis-inducing component in licorice.
PUBDATE: 20021001
The 70% methanol soluble fraction from a licorice acetone extract was found to inhibit cell proliferation in human monoblastic leukemia U937 cells by inducing apoptosis. Separation by the methods including preparative HPLC provided us with an active compound, which was identified as licocoumarone. Several lines of evidence indicated that licocoumarone induced apoptosis in U937 cells. Thus, licocoumarone is suggested to be potentially useful as a natural anti-cancer agent.


13. DOCID:31888 SCORE: 0.001436764145959
DOCNO: 15330895
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Practice Guidelines
QUALIFIER: diagnosis
QUALIFIER: statistics & numerical data
QUALIFIER: diagnosis
QUALIFIER: statistics & numerical data
QUALIFIER: standards
AUTHOR: Andrew D Feld AD
AFFILIATION: University of Washington.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: United States
TITLE: Malpractice risks associated with colon cancer and inflammatory bowel disease.
PUBDATE: 20040901
Analyses of lawsuits against gastroenterologists suggest that the disorders of colon cancer and inflammatory bowel disease are among the more common disorders resulting in malpractice claims, with colon cancer suits receiving some of the highest monetary judgments. Unfortunately, that composite data does not specify the exact alleged wrongdoing, but uses global categories such as "errors of diagnosis." This review will focus on potential legal pitfalls regarding those disorders. The focus is on the legal theories, not the exact medical approach recommended, and is intended as general education, and not legal advice for any specific patient.


14. DOCID:31969 SCORE: 0.0014367633636038
DOCNO: 11929036
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: drug therapy
QUALIFIER: etiology
AUTHOR: Munni Ray M
AUTHOR: R K Marwaha RK
AUTHOR: Amita Trehan A
AFFILIATION: Division of Pediatric Hematology-Oncology, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Indian journal of pediatrics.
COUNTRY: India
TITLE: Chemotherapy related fatal neurotoxicity during induction in acute lymphoblastic leukemia.
PUBDATE: 20020201
Neurotoxicity is a common complication during cancer chemotherapy. It is estimated that 3-10% of children with acute lymphoblastic leukemia (ALL) experience acute, transient neurotoxicity during induction chemotherapy. Fatal acute neurotoxicity is rarely encountered. Neurological evaluation of children with ALL at diagnosis and during treatment is of value in order to diagnose neurological complications early so that appropriate intervention can be adopted. This communication describes the profile of two children with unexpected, acute fatal neurologic toxicity during induction chemotherapy for ALL.