0. DOCID:10894 SCORE: 0.00310170881072735
DOCNO: 6410105
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: M Abe M
AUTHOR: M Takahashi M
AUTHOR: K Ono K
AUTHOR: Y Dodo Y
AUTHOR: M Hiraoka M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Intraoperative radiotherapy for locally advanced refractory cancer]
PUBDATE: 19830501
Clinical results of intraoperative radiotherapy (IOR) in carcinoma of the stomach and prostate, and malignant soft tissue tumors are reported. The 5-year survival rate was found to be increased by IOR in stages II-IV gastric cancer. From the analysis of the clinical results of prostatic cancer, a single dose of 3,500 rad was considered to be a potential curative dose for the tumor less than 3 cm in diameter. The local recurrence rate of patients with malignant soft tissue tumors who received a single dose ranging from 3,000 to 4,500 rad was 5.9 and the 5-year survival rate was 64.6%.


1. DOCID:11680 SCORE: 0.00298828475605901
DOCNO: 6468285
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: G J Röth GJ
AUTHOR: E Schirner E
AUTHOR: O P Hornstein OP
AUTHOR: M Simon M
PUBTYPE: Journal Article
JOURNALTITLE: Deutsche medizinische Wochenschrift (1946)
COUNTRY: GERMANY, WEST
TITLE: [Precancerous conditions and carcinomas of the lower lip. Coincidence with leukoplakia and carcinomas of the oral cavity and larynx]
PUBDATE: 19840801
In a prospective study of 102 patients with pre-neoplasia and/or manifest squamous-cell carcinoma of the lower lip the synchronous occurrence of intra-oral, pharyngeal or laryngeal leukoplakia and carcinoma was assessed. There was a coincidence rate of almost 15% leukoplakias, including individual carcinomas. This high coincidence is probably due to a combination of various "risk profiles" in patients with threatened or manifest lower-lip cancer. Chronic exposure to sunlight, especially in the presence of a genetic disposition, is the most important risk factor in lower-lip cancer and its preceding stages, while chronic alcoholism and smoking abuse have little etiological significance.


2. DOCID:9109 SCORE: 0.00256538673069854
DOCNO: 6837865
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: D Tong D
AUTHOR: A H Russell AH
AUTHOR: L E Dawson LE
AUTHOR: W Wisbeck W
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Second laparotomy for proximal colon cancer. Sites of recurrence and implications for adjuvant therapy.
PUBDATE: 19830301
Sixty-four patients with primary adenocarcinomas of the colon proximal to the peritoneal reflection underwent exploratory laparotomy at the time of first recurrence of their cancers. Local recurrence, retroperitoneal lymph node metastases, parenchymal liver metastases, and diffuse peritoneal seeding were identified as frequent components of the overall pattern of recurrence. The significance of these findings has been discussed herein, relative to refinements of operative technique and selection of appropriate adjuvant therapy.


3. DOCID:9880 SCORE: 0.00248506848162321
DOCNO: 6319654
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H F Hull HF
AUTHOR: J D Blumhagen JD
AUTHOR: D Benjamin D
AUTHOR: L Corey L
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of pediatrics.
COUNTRY: UNITED STATES
TITLE: Herpes simplex viral pneumonitis in childhood.
PUBDATE: 19840201
We report two cases of herpes simplex pneumonia in children. One patient had Down syndrome, and the other was immunosuppressed by cancer therapy. Both had interstitial pneumonitis with nonspecific physical, radiographic, and laboratory findings, and both died. The diagnosis of herpes simplex pneumonia was made by isolation of herpes simplex virus from autopsy lung cultures as well as by demonstration of antigen in the tissue with an immunoperoxidase procedure. Inasmuch as herpes simplex pneumonia is a potentially treatable infection, early virologic studies are recommended in immunocompromised children with progressive pneumonitis of undetermined cause.


4. DOCID:10249 SCORE: 0.00232620394428387
DOCNO: 6215980
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: C J Lightdale CJ
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Laparoscopy and biopsy in malignant liver disease.
PUBDATE: 19821201
Laparoscopy is highly effective in diagnosing malignant liver disease, with overall accuracy in the 90% range. Up to 80% of the liver surface can be inspected, and biopsies can be directed with precision. A major advantage over scan guided percutaneous techniques is the ability to detect and biopsy lesions only a few millimeters in size on the liver surface. Laparoscopy is useful in staging the liver for metastatic disease during evaluation for treatment of primary cancers. Small peritoneal metastases may also be discovered and biopsied. Primary liver cancers and isolated metastatic deposits can be assessed for resectability, and diagnostic laparotomy can often be avoided. Laparoscopy is safely performed under local anesthesia and mild sedation.


5. DOCID:9707 SCORE: 0.0022477713289454
DOCNO: 6527953
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: K E Andersen KE
AUTHOR: R Lindskov R
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Photo-dermatology.
COUNTRY: DENMARK
TITLE: Recall of UVB-induced erythema in breast cancer patient receiving multiple drug chemotherapy.
PUBDATE: 19840601
One day after sunbathing, a breast cancer patient received intravenous methotrexate, cyclophosphamide and 5-fluorouracil and had a recall of her UV erythema over the following week. Phototesting with UVA and UVB prior to and after a subsequent chemotherapy treatment showed a UVB-induced recall of erythema, as well as a phototoxicity-like response. Skin biopsies from test sites were compatible with phototoxic dermatitis. The occurrence of both erythema recall and the phototoxicity-like reaction suggests that more than one mechanism is involved in this side effect.


6. DOCID:11312 SCORE: 0.00201632813041769
DOCNO: 7052040
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: D R Bell DR
AUTHOR: R L Woods RL
AUTHOR: J A Levi JA
AUTHOR: R M Fox RM
AUTHOR: M H Tattersall MH
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Australian and New Zealand journal of medicine.
COUNTRY: AUSTRALIA
TITLE: Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum.
PUBDATE: 19820601
Thirty-seven patients with advanced ovarian cancer were treated in a prospective, randomised trial comparing chlorambucil with a combination of cyclophosphamide and cis-diamminedichloroplatinum (cis DDP). Treatment with the combination was associated with an increased overall response rate (69% versus 23%) (p = 0.04). A response was associated with a longer median survival but no survival advantage was demonstrated for patients who received cyclophosphamide/cis DDP. A larger study is needed to evaluate fully the potential of regimens containing cis DDP in the management of advanced ovarian cancer.


7. DOCID:11797 SCORE: 0.00197227178536484
DOCNO: 7141213
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
QUALIFIER: psychology
AUTHOR: L A Bieliauskas LA
AUTHOR: D C Garron DC
PUBTYPE: Journal Article
JOURNALTITLE: General hospital psychiatry.
COUNTRY: UNITED STATES
TITLE: Psychological depression and cancer.
PUBDATE: 19820901
Studies are reviewed which relate to five basic content areas of research concerning depression and cancer: significant loss experience, emotional inhibition, hopelessness, psychiatric assessment of depression, and test measurement of depression. Methodological issues within each area are addressed as they relate to the potential validity and generalizability of findings. In general, there is no support for increased loss experience in cancer patients and mild support for increased emotional inhibition and hopelessness in these individuals. Traditional psychiatric assessment approaches are not seen as providing solid evidence for a depression/cancer relationship due to reliability and design issues, while psychometric assessment provides mild support for a prospective relationship between depression and later cancer. Issues relating to approaches to research, means of measurement of depression, design issues, and questions of conceptualization of depression are discussed.


8. DOCID:11874 SCORE: 0.00196746178519235
DOCNO: 4065347
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
QUALIFIER: adverse effects
QUALIFIER: psychology
AUTHOR: A Eardley A
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Radiotherapy: what are patients' needs?
PUBDATE: 19851201
Although there is a substantial body of research into the impact of cancer therapies such as surgery and chemotherapy, little is known about the experiences of cancer patients receiving radiotherapy. Serial interviews with 39 patients undergoing radical radiotherapy to the oral cavity revealed that misunderstandings and groundless fears about this form of treatment were widespread. A majority were unprepared for the severity and duration of their side-effects. These results suggest that written information for patients about radiotherapy and its side-effects should be made available routinely. There is also scope for nutritional support. Finally, as a supplement to out-patient attendance, informal contact with the hospital in the immediate post-treatment phase would provide invaluable reassurance to patients.


9. DOCID:8740 SCORE: 0.00179956951550357
DOCNO: 6612384
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: D G Folks DG
AUTHOR: A I Alexander AI
AUTHOR: P L Rabin PL
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Southern medical journal.
COUNTRY: UNITED STATES
TITLE: Psychiatric disturbance in Hodgkin's disease.
PUBDATE: 19830901
We describe the onset of psychotic depression in a young man receiving intensive therapy for Hodgkin's disease. We have found other examples of psychiatric disturbance in the course of reviewing the charts of 40 men with Hodgkin's disease and 20 with testicular cancer. We propose that patients with oncologic disease and their families receive counseling before initiation of treatment and be advised about the availability of psychiatric help should it become necessary.


10. DOCID:11076 SCORE: 0.00178582764941545
DOCNO: 3971795
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Colonic Neoplasms
DESCRIPTOR: Rectal Neoplasms
QUALIFIER: administration & dosage
QUALIFIER: instrumentation
QUALIFIER: secondary
AUTHOR: G C Oliver GC
AUTHOR: P E Shorb PE
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: The totally implantable infusion pump in treatment of metastatic colorectal cancer.
PUBDATE: 19850101
Final evaluation of the Infusaid Pump system (Infusaid Corporation, Sharon, MA) for administration of regional chemotherapy must await completion of trials prospectively comparing survival of matched patients treated in this manner and patients treated by traditional systemic chemotherapy. A review of the current medical literature confirms our personal experience that response rates within the liver are high. Survival reports appear encouraging but this may represent an artifact in patient selection. An algorithm is presented to offer surgeons a reasonable and conservative means for selection of those colorectal cancer patients with metastatic involvement of the liver who are most likely to benefit from this system of drug delivery.


11. DOCID:11513 SCORE: 0.00178090166945758
DOCNO: 6381786
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bone Marrow Transplantation
QUALIFIER: therapeutic use
QUALIFIER: drug effects
QUALIFIER: therapy
AUTHOR: S Nakamura S
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Myelotoxicity due to cancer chemotherapy with special reference to autologous bone marrow transplantation]
PUBDATE: 19840701
In order to know the myelotoxicity due to combination cancer chemotherapy, the hematologic changes in 15 patients with non-Hodgkin's lymphoma (NHL) treated with combination chemotherapy using adriamycin, cyclophosphamide, vincristine and prednisolone (ACOP protocol) were observed. From this study, it was confirmed that neutrophil leukocyte depletion is one of the most important dose-limiting factors of combination cancer chemotherapy. Our experience of autologous bone marrow transplantation for 15 patients with malignant tumors, such as NHL, small cell lung cancer, nasopharyngeal carcinoma, clearly demonstrated that cryopreserved autologous bone marrow cells can rescue cancer patients from marrow-lethal doses of drugs and irradiation and thus prompts us to establish a new protocol to eradicate tumor cells.


12. DOCID:11454 SCORE: 0.00178090127900494
DOCNO: 6471417
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: H Yamauchi H
AUTHOR: T Sato T
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Carcinoma of the pancreas: mode of spread and magnitude of surgical management]
PUBDATE: 19840701
We have resected 34 carcinomas of head of the pancreas and seven of body and tail of the pancreas in the past 23 years. The one, three and five year survival rate of carcinoma of the pancreas after resection was 53, 20 and 9 per cent respectively. Duodenopancreatectomy is possibly a rational procedure to cure well-defined pancreatic cancer of head without capsular invasion, while total pancreatectomy has validity to be done for ill-defined pancreatic cancer or for carcinoma with positive capsular invasion. High incidence of vein invasion in histological sections and nearly one hundred per cent of liver metastases in postmortem examination of the patients whose malignancies were previously resected indicated negative aspect against surgical treatment.


13. DOCID:11899 SCORE: 0.00174187123205835
DOCNO: 6467219
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Embalming
DESCRIPTOR: Mortality
QUALIFIER: mortality
AUTHOR: J Walrath J
AUTHOR: J F Fraumeni JF
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: Cancer and other causes of death among embalmers.
PUBDATE: 19841001
To evaluate the potential carcinogenic effects of formaldehyde, we examined the proportionate mortality experience of embalmers licensed to practice in California. Mortality was significantly elevated for total cancer, arteriosclerotic heart disease, and suicide, whereas significant deficits were noted in mortality from diseases of the respiratory and genitourinary systems. Deaths from cancers of the brain, colon, and prostate and leukemia were significantly higher than expected. No increased mortality was seen for cancers of the respiratory tract, including the nasal passages, where an effect might be expected based on animal studies. A parallel mortality survey of embalmers from New York State showed similar findings, with excesses of brain tumors, leukemia, colon cancer, arteriosclerotic heart disease, and cirrhosis. Further investigation is needed to determine whether any of these outcomes is related to formaldehyde exposure.


14. DOCID:11943 SCORE: 0.00174187086699131
DOCNO: 7055820
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: R Bukowski R
AUTHOR: C Vaughn C
AUTHOR: R Bottomley R
AUTHOR: T Chen T
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Phase II study of anguidine in gastrointestinal malignancies: a Southwest Oncology Group study.
PUBDATE: 19820201
The Southwest Oncology Group conducted a phase II study of anguidine in 134 patients with gastrointestinal malignancies. Anguidine was administered as a 4-hour infusion at doses of 3.0 and 4.5 mg/m2 daily x 5. Response rates for patients with colon carcinoma were 22% (four of 18 patients without previous chemotherapy) and 6% (four of 63 patients with previous chemotherapy). There were no responses in patients with pancreatic cancer (four patients) or gastric cancer (six). Toxic effects included thrombocytopenia (19.8%), leukopenia (18.8%), nausea and vomiting (49%), hypotension (37%), and confusion (12%). Antitumor activity of anguidine in patients with colon cancer may be similar to that of 5-FU, but nonhematologic toxicity is substantial.