0. DOCID:10894 SCORE: 0.00310170881072735
DOCNO: 6410105
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: M Abe M
AUTHOR: M Takahashi M
AUTHOR: K Ono K
AUTHOR: Y Dodo Y
AUTHOR: M Hiraoka M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Intraoperative radiotherapy for locally advanced refractory cancer]
PUBDATE: 19830501
Clinical results of intraoperative radiotherapy (IOR) in carcinoma of the stomach and prostate, and malignant soft tissue tumors are reported. The 5-year survival rate was found to be increased by IOR in stages II-IV gastric cancer. From the analysis of the clinical results of prostatic cancer, a single dose of 3,500 rad was considered to be a potential curative dose for the tumor less than 3 cm in diameter. The local recurrence rate of patients with malignant soft tissue tumors who received a single dose ranging from 3,000 to 4,500 rad was 5.9 and the 5-year survival rate was 64.6%.

1. DOCID:11680 SCORE: 0.00298828475605901
DOCNO: 6468285
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: G J Röth GJ
AUTHOR: E Schirner E
AUTHOR: O P Hornstein OP
AUTHOR: M Simon M
PUBTYPE: Journal Article
JOURNALTITLE: Deutsche medizinische Wochenschrift (1946)
COUNTRY: GERMANY, WEST
TITLE: [Precancerous conditions and carcinomas of the lower lip. Coincidence with leukoplakia and carcinomas of the oral cavity and larynx]
PUBDATE: 19840801
In a prospective study of 102 patients with pre-neoplasia and/or manifest squamous-cell carcinoma of the lower lip the synchronous occurrence of intra-oral, pharyngeal or laryngeal leukoplakia and carcinoma was assessed. There was a coincidence rate of almost 15% leukoplakias, including individual carcinomas. This high coincidence is probably due to a combination of various "risk profiles" in patients with threatened or manifest lower-lip cancer. Chronic exposure to sunlight, especially in the presence of a genetic disposition, is the most important risk factor in lower-lip cancer and its preceding stages, while chronic alcoholism and smoking abuse have little etiological significance.

2. DOCID:9109 SCORE: 0.00256538673069854
DOCNO: 6837865
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: D Tong D
AUTHOR: A H Russell AH
AUTHOR: L E Dawson LE
AUTHOR: W Wisbeck W
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Second laparotomy for proximal colon cancer. Sites of recurrence and implications for adjuvant therapy.
PUBDATE: 19830301
Sixty-four patients with primary adenocarcinomas of the colon proximal to the peritoneal reflection underwent exploratory laparotomy at the time of first recurrence of their cancers. Local recurrence, retroperitoneal lymph node metastases, parenchymal liver metastases, and diffuse peritoneal seeding were identified as frequent components of the overall pattern of recurrence. The significance of these findings has been discussed herein, relative to refinements of operative technique and selection of appropriate adjuvant therapy.

3. DOCID:9880 SCORE: 0.00248506848162321
DOCNO: 6319654
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H F Hull HF
AUTHOR: J D Blumhagen JD
AUTHOR: D Benjamin D
AUTHOR: L Corey L
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of pediatrics.
COUNTRY: UNITED STATES
TITLE: Herpes simplex viral pneumonitis in childhood.
PUBDATE: 19840201
We report two cases of herpes simplex pneumonia in children. One patient had Down syndrome, and the other was immunosuppressed by cancer therapy. Both had interstitial pneumonitis with nonspecific physical, radiographic, and laboratory findings, and both died. The diagnosis of herpes simplex pneumonia was made by isolation of herpes simplex virus from autopsy lung cultures as well as by demonstration of antigen in the tissue with an immunoperoxidase procedure. Inasmuch as herpes simplex pneumonia is a potentially treatable infection, early virologic studies are recommended in immunocompromised children with progressive pneumonitis of undetermined cause.

4. DOCID:10249 SCORE: 0.00232620394428387
DOCNO: 6215980
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: C J Lightdale CJ
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Laparoscopy and biopsy in malignant liver disease.
PUBDATE: 19821201
Laparoscopy is highly effective in diagnosing malignant liver disease, with overall accuracy in the 90% range. Up to 80% of the liver surface can be inspected, and biopsies can be directed with precision. A major advantage over scan guided percutaneous techniques is the ability to detect and biopsy lesions only a few millimeters in size on the liver surface. Laparoscopy is useful in staging the liver for metastatic disease during evaluation for treatment of primary cancers. Small peritoneal metastases may also be discovered and biopsied. Primary liver cancers and isolated metastatic deposits can be assessed for resectability, and diagnostic laparotomy can often be avoided. Laparoscopy is safely performed under local anesthesia and mild sedation.

5. DOCID:14956 SCORE: 0.00230825148992505
DOCNO: 3784819
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: radiotherapy
AUTHOR: S Iu Morozova SIu
AUTHOR: O N Spasokukotskaia ON
AUTHOR: V N Chekhonadskiĭ VN
AUTHOR: T A Strel'nitskaia TA
AUTHOR: K Merkle K
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Topometric preparation of patients with cervix cancer for intracavitary irradiation on the ANET-B apparatus]
PUBDATE: 19861101
The authors worked out methods of topometric investigation of cervical cancer patients during preparation for intracavitary irradiation using 252Cf fast neutron sources. The use of balloon catheters made it possible to determine a coefficient of projection enlargement in the point of interest, to determine accurately the distance between endostats, sources and contrasted organs of interest: the bladder and rectum. The results of the studies were used for individual design of intracavitary treatment as well as for the determination of radiation exposure of the pelvic organs in 38 patients. The patients received a total of 138 investigations.

6. DOCID:14749 SCORE: 0.00226736952824448
DOCNO: 2532269
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
QUALIFIER: drug therapy
AUTHOR: R I Nicholson RI
AUTHOR: K J Walker KJ
AFFILIATION: Tenovus Institute for Cancer Research, University of Wales, College of Medicine, Heath Park, Cardiff, U.K.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of steroid biochemistry.
COUNTRY: ENGLAND
TITLE: Gn-RH agonists in breast and gynaecologic cancer treatment.
PUBDATE: 19891001
The effects of Gn-RH agonists in advanced breast cancer patients have been examined. In both pre- and postmenopausal women they produce pituitary gland desensitisation and a fall in circulating concentrations of LH and FSH. In premenopausal patients plasma progesterone and oestradiol levels fall to the castrate or postmenopausal range within 3-4 weeks. Tumour remissions have been observed in approximately 30% of premenopausal women and approximately 10% of postmenopausal patients. The mechanism of action of Gn-RH agonists is discussed and their use projected to other tumour types.

7. DOCID:9707 SCORE: 0.0022477713289454
DOCNO: 6527953
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: K E Andersen KE
AUTHOR: R Lindskov R
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Photo-dermatology.
COUNTRY: DENMARK
TITLE: Recall of UVB-induced erythema in breast cancer patient receiving multiple drug chemotherapy.
PUBDATE: 19840601
One day after sunbathing, a breast cancer patient received intravenous methotrexate, cyclophosphamide and 5-fluorouracil and had a recall of her UV erythema over the following week. Phototesting with UVA and UVB prior to and after a subsequent chemotherapy treatment showed a UVB-induced recall of erythema, as well as a phototoxicity-like response. Skin biopsies from test sites were compatible with phototoxic dermatitis. The occurrence of both erythema recall and the phototoxicity-like reaction suggests that more than one mechanism is involved in this side effect.

8. DOCID:13645 SCORE: 0.00212797373823985
DOCNO: 3803604
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Oncogenes
QUALIFIER: metabolism
QUALIFIER: genetics
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: Y Kubota Y
AUTHOR: T Shuin T
AUTHOR: M Yao M
AUTHOR: H Inoue H
AUTHOR: T Yoshioka T
PUBTYPE: Journal Article
JOURNALTITLE: FEBS letters.
COUNTRY: NETHERLANDS
TITLE: The enhanced 32P labeling of CDP-diacylglycerol in c-myc gene expressed human kidney cancer cells.
PUBDATE: 19870201
Correlation between c-myc gene expression and phosphatidylinositol (PI) metabolism was studied using seven human kidney cancer cell lines. We found that the exceptional incorporation of 32P into CDP-diacylglycerol (CDP-DG) was observed in only two cell lines, in which c-myc expression was increased among seven cell lines tested. In these two cell lines, PI was also labeled. The other five cell lines indicated the accumulation of radioactive PI, whereas CDP-DG was unlabeled.

9. DOCID:13909 SCORE: 0.00209217440388121
DOCNO: 3345953
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Postoperative Complications
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: surgery
AUTHOR: A Ilancheran A
AUTHOR: J M Monaghan JM
AFFILIATION: Regional Department of Gynecologic Oncology, Queen Elizabeth Hospital, Gateshead, United Kingdom.
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Pelvic lymphocyst--a 10-year experience.
PUBDATE: 19880301
Pelvic lymphocysts occur infrequently after radical surgery for cervical cancer. The problem is one of recognition. In a retrospective analysis of patients seen over 10 years in this department, the incidence was 25.3%. All were diagnosed by bimanual, clinical examination only. The only factor that appears to relate to the formation of lymphocysts is the presence of poorly differentiated tumors; 70.8% of patients developing lymphocysts had poorly differentiated tumors. All the lymphocysts in this series resolved spontaneously and did not produce any major complications.

10. DOCID:14619 SCORE: 0.00206722389893322
DOCNO: 2543031
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Humerus
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: R W Schulte RW
AUTHOR: I A Adamietz IA
AUTHOR: K Renner K
AUTHOR: I Falkenreck I
AFFILIATION: Institut für Strahlentherapie und spezielle Onkologie, Medizinische Hochschule Hannover.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Der Radiologe.
COUNTRY: GERMANY, WEST
TITLE: [Humeral head necrosis following irradiation of breast carcinoma. A case report]
PUBDATE: 19890501
Radiation-induced osteoradionecrosis of the ribs and brachial plexus lesions following irradiation of breast cancer patients are well known phenomena and have been reported several times in the literature. Damage to the shoulder joint after irradiation is uncommon. The case of a 75-year-old woman with breast cancer is described; she first developed a brachial plexopathy and then necrosis of the head of humerus after therapy with combined ortho-voltage and high-voltage radiation. The differential diagnosis and possible pathogenetic mechanisms are discussed.

11. DOCID:15941 SCORE: 0.00203433729869347
DOCNO: 2554382
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: diagnosis
QUALIFIER: methods
AUTHOR: G Layer G
AUTHOR: I Zuna I
AUTHOR: A Lorenz A
AUTHOR: U Haberkorn U
AUTHOR: H Zerban H
AUTHOR: P Bannasch P
AUTHOR: G van Kaick G
AUTHOR: U Räth U
AFFILIATION: Institut für Radiologie und Pathophysiologie, Deutsches Krebsforschungszentrum, Heidelberg.
PUBTYPE: Journal Article
JOURNALTITLE: RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin.
COUNTRY: GERMANY, WEST
TITLE: [Computer-assisted ultrasonic B-scan texture analysis of experimental liver tumors]
PUBDATE: 19891001
Primary liver cancer has been induced experimentally in female Wistar rats by diaminoazobenzene intoxication or subcapsular liver implantation of Novikoff cell suspensions. The ultrasonic B-scan image of these malignant tumours are described via statistical texture parameters in respect of image brightness, microtexture and macrotexture. A discrimination of the tumour texture profiles is possible with an accuracy of about 80%. There are correlations between ultrasonic image parameters and histomorphological tissue components but there is no specific link between the histological tumour-type and these B-scan data.

12. DOCID:11312 SCORE: 0.00201632813041769
DOCNO: 7052040
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: D R Bell DR
AUTHOR: R L Woods RL
AUTHOR: J A Levi JA
AUTHOR: R M Fox RM
AUTHOR: M H Tattersall MH
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Australian and New Zealand journal of medicine.
COUNTRY: AUSTRALIA
TITLE: Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum.
PUBDATE: 19820601
Thirty-seven patients with advanced ovarian cancer were treated in a prospective, randomised trial comparing chlorambucil with a combination of cyclophosphamide and cis-diamminedichloroplatinum (cis DDP). Treatment with the combination was associated with an increased overall response rate (69% versus 23%) (p = 0.04). A response was associated with a longer median survival but no survival advantage was demonstrated for patients who received cyclophosphamide/cis DDP. A larger study is needed to evaluate fully the potential of regimens containing cis DDP in the management of advanced ovarian cancer.

13. DOCID:11797 SCORE: 0.00197227178536484
DOCNO: 7141213
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
QUALIFIER: psychology
AUTHOR: L A Bieliauskas LA
AUTHOR: D C Garron DC
PUBTYPE: Journal Article
JOURNALTITLE: General hospital psychiatry.
COUNTRY: UNITED STATES
TITLE: Psychological depression and cancer.
PUBDATE: 19820901
Studies are reviewed which relate to five basic content areas of research concerning depression and cancer: significant loss experience, emotional inhibition, hopelessness, psychiatric assessment of depression, and test measurement of depression. Methodological issues within each area are addressed as they relate to the potential validity and generalizability of findings. In general, there is no support for increased loss experience in cancer patients and mild support for increased emotional inhibition and hopelessness in these individuals. Traditional psychiatric assessment approaches are not seen as providing solid evidence for a depression/cancer relationship due to reliability and design issues, while psychometric assessment provides mild support for a prospective relationship between depression and later cancer. Issues relating to approaches to research, means of measurement of depression, design issues, and questions of conceptualization of depression are discussed.

14. DOCID:11874 SCORE: 0.00196746178519235
DOCNO: 4065347
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
QUALIFIER: adverse effects
QUALIFIER: psychology
AUTHOR: A Eardley A
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Radiotherapy: what are patients' needs?
PUBDATE: 19851201
Although there is a substantial body of research into the impact of cancer therapies such as surgery and chemotherapy, little is known about the experiences of cancer patients receiving radiotherapy. Serial interviews with 39 patients undergoing radical radiotherapy to the oral cavity revealed that misunderstandings and groundless fears about this form of treatment were widespread. A majority were unprepared for the severity and duration of their side-effects. These results suggest that written information for patients about radiotherapy and its side-effects should be made available routinely. There is also scope for nutritional support. Finally, as a supplement to out-patient attendance, informal contact with the hospital in the immediate post-treatment phase would provide invaluable reassurance to patients.