0. DOCID:23624 SCORE: 0.00417443106118014
DOCNO: 8869951
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: A Schneider A
AUTHOR: D M Zahm DM
AFFILIATION: Department of Gynecology, Friedrich Schiller University, Jena, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Obstetrics and gynecology clinics of North America.
COUNTRY: UNITED STATES
TITLE: New adjunctive methods for cervical cancer screening.
PUBDATE: 19960901
The sensitivity of cytology for detection of cervical intraepithelial neoplasia (CIN) is effectively augmented by cervicography with the disadvantage of lower specificity. However, the combination of cytology and cervicography can decrease the number of recalls, biopsies, and unnecessary treatments, which reduces cost. Down-staging of invasive cancer by visual inspection seems a cost-effective alternative to the introduction of cytology in countries with limited health facilities. Other methods such as speculoscopy, polarprobe, laser-induced fluorescence, computerized digital imaging colposcopy, or computer imaging have a potential to be used for future screening or triaging; however, so far, insufficient data are available to evaluate the validity of these techniques.


1. DOCID:7381 SCORE: 0.00380148467146802
DOCNO: 717271
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: metabolism
AUTHOR: E R Eichner ER
AUTHOR: C R McDonald CR
AUTHOR: V L Dickson VL
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of clinical nutrition.
COUNTRY: UNITED STATES
TITLE: Elevated serum levels of unsaturated folate binding protein: clinical correlates in a general hospital population.
PUBDATE: 19781101
We measured the capactiy of unsaturated folate binding protein to bind 3H-pteroylglutamic acid (UFBC) in serums from 489 general hospital patients. Of the patients 20% had mild-to-moderate elevations in UFBC (250 to 500 pg/ml), but only 6% had marked elevations (greater than 650 pg/ml), which correlated with metastatic cancer, active granulomatous disease, and especially with liver disease. The poor correlation of serum UFBC with folate status of the patient suggests that in many instances the elevated serum UFBC is neither the consequence nor the cause of folate deficiency. Although the role of folate binding protein remains unknown, it may be primarily an intracellular protein that is released into the serum as an index of activity of liver cells, granulocytes, and perhaps certain cancer cells.


2. DOCID:27917 SCORE: 0.00342279938431071
DOCNO: 10950461
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: genetics
AUTHOR: R W Burt RW
AFFILIATION: Department of Medicine, University of Utah, College of Medicine, and Huntsman Cancer Institute, Salt Lake City, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Seminars in gastrointestinal disease.
COUNTRY: UNITED STATES
TITLE: Rare syndromes and genetic testing for colorectal cancer.
PUBDATE: 20000701
The genes responsible for each of the inherited syndromes of intestinal polyposis and colorectal cancer are now known. This knowledge has led to genetic testing for syndrome diagnosis and for determining which persons in an affected family actually have the condition. Genetic testing has also allowed a more precise clinical characterization of each of the syndromes and their subtypes. Optimal application of genetic testing, proper cancer prevention, and management of nonmalignant features of each of the syndromes are the next goals. This report summarizes each of the syndromes, their genetics, and management and provides an approach for genetic testing.


3. DOCID:6879 SCORE: 0.00318038610868272
DOCNO: 7442196
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Speech
DESCRIPTOR: Speech Acoustics
QUALIFIER: physiopathology
AUTHOR: T Murry T
AUTHOR: E T Doherty ET
PUBTYPE: Journal Article
JOURNALTITLE: Journal of speech and hearing research.
COUNTRY: UNITED STATES
TITLE: Selected acoustic characteristics of pathologic and normal speakers.
PUBDATE: 19800601
The purpose of this study was to determine if measures of speaking fundamental frequency and its perturbation could be useful in differentiating talkers with no known vocal pathology and talkers with cancer of the larynx. Ten male subjects, five with a diagnosed malignancy of the larynx and five with normal voice, produced speech samples from which five voice production measures were obtained: the average speaking fundamental frequency (SFF), SFF variability during the reading of a sentence, the fo of a sustained vowel and a percent and magnitude jitter value. The perturbation factors, both directional and magnitudinal, during sustained vowels were found to be significant in discriminating normal talkers from those with laryngeal cancer. The speaking fundamental frequency and its variability during the reading of a sentence improved the discriminant function.


4. DOCID:3896 SCORE: 0.0031511091785644
DOCNO: 1192433
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Precancerous Conditions
QUALIFIER: pathology
QUALIFIER: etiology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: K Toyoshima K
AUTHOR: J Leighton J
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: Bladder calculi and urothelial hyperplasia with papillomatosis in the rat following insertion of chalk powder in the bladder cavity with subsequent trauma of the bladder wall.
PUBDATE: 19751201
A suspension of chalk powder was injected into the cavity of the urinary bladder of Fischer 344 rats. Three weeks later rats were divided into 4 major groups and were given a submucosal injection. One group received a suspension of viable Chapman 4909 tumor cells, the 2nd group received a suspension of frozen-killed 4909 tumor cells, the 3rd group received a suspension of normal rat spleen cells, and the 4th group received cell-free fresh tissue culture medium. After 3 additional weeks urolithiasis was recognized in each experimental group. The incidence of calculi in the groups as listed above was 14 of 17, 6 of 11, 6 of 11, and 2 of 15, respectively. In control studies inocula consisted of tumor alone, i.e., without chalk powder. Inoculation of the 4909 rat bladder cancer cell line into the lumen of urinary bladders of rats did not result in any calculi after 3 weeks but did produce intramural tumor nodules and hyperplastic changes in adjacent host urothelium in 2 of 10 rats. The tumor inoculated in the submucosa of the bladder produced calculi and papillomas in 2 of 7 rats, and it produced intramural tumor nodules with adjacent hyperplasia of urothelium in all 7 rats.


5. DOCID:10894 SCORE: 0.00310170881072735
DOCNO: 6410105
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: M Abe M
AUTHOR: M Takahashi M
AUTHOR: K Ono K
AUTHOR: Y Dodo Y
AUTHOR: M Hiraoka M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Intraoperative radiotherapy for locally advanced refractory cancer]
PUBDATE: 19830501
Clinical results of intraoperative radiotherapy (IOR) in carcinoma of the stomach and prostate, and malignant soft tissue tumors are reported. The 5-year survival rate was found to be increased by IOR in stages II-IV gastric cancer. From the analysis of the clinical results of prostatic cancer, a single dose of 3,500 rad was considered to be a potential curative dose for the tumor less than 3 cm in diameter. The local recurrence rate of patients with malignant soft tissue tumors who received a single dose ranging from 3,000 to 4,500 rad was 5.9 and the 5-year survival rate was 64.6%.


6. DOCID:11680 SCORE: 0.00298828475605901
DOCNO: 6468285
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: G J Röth GJ
AUTHOR: E Schirner E
AUTHOR: O P Hornstein OP
AUTHOR: M Simon M
PUBTYPE: Journal Article
JOURNALTITLE: Deutsche medizinische Wochenschrift (1946)
COUNTRY: GERMANY, WEST
TITLE: [Precancerous conditions and carcinomas of the lower lip. Coincidence with leukoplakia and carcinomas of the oral cavity and larynx]
PUBDATE: 19840801
In a prospective study of 102 patients with pre-neoplasia and/or manifest squamous-cell carcinoma of the lower lip the synchronous occurrence of intra-oral, pharyngeal or laryngeal leukoplakia and carcinoma was assessed. There was a coincidence rate of almost 15% leukoplakias, including individual carcinomas. This high coincidence is probably due to a combination of various "risk profiles" in patients with threatened or manifest lower-lip cancer. Chronic exposure to sunlight, especially in the presence of a genetic disposition, is the most important risk factor in lower-lip cancer and its preceding stages, while chronic alcoholism and smoking abuse have little etiological significance.


7. DOCID:25174 SCORE: 0.00298481334753327
DOCNO: 11301470
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Angiography
DESCRIPTOR: Radiography, Thoracic
QUALIFIER: blood supply
QUALIFIER: abnormalities
AUTHOR: J M Pilcher JM
AUTHOR: A R Padhani AR
AFFILIATION: Academic Department of Diagnostic Radiology, The Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom. pilmac@waitrose.com
PUBTYPE: Journal Article
JOURNALTITLE: Clinical anatomy (New York, N.Y.)
COUNTRY: United States
TITLE: Problem in diagnostic imaging: Mediastinal venous anomalies.
PUBDATE: 20010501
This article presents as a diagnostic problem a rare mediastinal venous anomaly detected in a patient with a primary intrathoracic tumor. Its appearance on computed tomography (CT) is discussed and compared with that of other developmental mediastinal venous anomalies. The individual CT characteristics of these anomalies and their clinical significance with respect to the management of patients with cancer are also reviewed.


8. DOCID:31947 SCORE: 0.00285880782073024
DOCNO: 12073121
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Buttocks
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: pathology
AUTHOR: Ik Yang I
AUTHOR: Curtis W Hayes CW
AUTHOR: J Sybil Biermann JS
AFFILIATION: Department of Radiology, University of Michigan Health Systems, Ann Arbor, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Skeletal radiology.
COUNTRY: Germany
TITLE: Calcific tendinitis of the gluteus medius tendon with bone marrow edema mimicking metastatic disease.
PUBDATE: 20020601
A case of calcific tendinitis of the gluteus medius is presented. This report describes a patient with a history of breast cancer who had the combination of amorphous calcifications in the gluteus medius tendon and the MR finding of conspicuous bone marrow edema in the adjacent greater trochanter, prompting concern for metastatic disease. We present images from radiography, bone scanning, CT, and MR imaging. The unusual combination of findings in these studies should be considered conclusive for calcific tendinitis, and should not be confused with malignancy.


9. DOCID:6865 SCORE: 0.00284825193584826
DOCNO: 7309279
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: blood
AUTHOR: H G Kwa HG
AUTHOR: F Cleton F
AUTHOR: R D Bulbrook RD
AUTHOR: D Y Wang DY
AUTHOR: J L Hayward JL
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: DENMARK
TITLE: Plasma prolactin levels and breast cancer: relation to parity, weight and height, and age at first birth.
PUBDATE: 19810701
Plasma prolactin has been measured in over 3,500 women volunteers from a normal population. In premenopausal women there was a significant decrease in prolactin levels with increasing parity. However, this effect was transitory since plasma prolactin concentration rose with increasing time after the birth of the last child. There were no significant differences in prolactin levels with respect to height and weight, although overweight compared to underweight women had approximately 15% more plasma prolactin. If prolactin is a carcinogen, then these results are in keeping with the epidemiological findings that multiparity affords protection and that age at last delivery is a risk factor in the development of breast cancer.


10. DOCID:19459 SCORE: 0.00270065906324982
DOCNO: 7691981
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: R J Hicks RJ
AFFILIATION: Department of Family Medicine, Oklahoma University Health Sciences Center, Oklahoma City.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of family practice.
COUNTRY: UNITED STATES
TITLE: Elevated prostate-specific antigen: a case report and analysis.
PUBDATE: 19930901
Prostate cancer is a frequent concern of the clinician caring for older male patients. The certainty of arriving at the correct diagnosis is related to the presenting patient's risk for prostate cancer, the results of the digital rectal examination, and the value of the serum prostate-specific antigen (PSA). A case report of a patient with acute urinary retention and an elevated PSA is presented. Possible explanations for the elevated PSA are discussed. The clinician's intuitive thought process is compared with an analytic approach using calculated probabilities. Several factors that complicate the estimation of the likelihood of prostate cancer are discussed.


11. DOCID:22247 SCORE: 0.00266363037888519
DOCNO: 7531737
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: therapy
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: A Caraceni A
AUTHOR: C Martini C
AUTHOR: F De Conno F
AUTHOR: V Ventafridda V
AFFILIATION: Pain Therapy and Palliative Care Division, National Cancer Institute, Milan, Italy.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pain and symptom management.
COUNTRY: UNITED STATES
TITLE: Organic brain syndromes and opioid administration for cancer pain.
PUBDATE: 19941101
To clarify the range of potential etiologies that may contribute to organic brain syndrome in patients receiving systemic opioids for cancer pain, we describe 15 patients who presented this complication. In 11 cases, concomitant conditions were found that could contribute to the onset of organic brain syndrome. These data illustrate that multiple causes often play a role in the development of mental status changes in advanced cancer. Opioids are seldom the only causal factor implicated.


12. DOCID:22206 SCORE: 0.00266362695609392
DOCNO: 8714805
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Body Image
DESCRIPTOR: Patient Care Team
DESCRIPTOR: Sick Role
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
AUTHOR: E J Kunkel EJ
AUTHOR: C Rodgers C
AUTHOR: H L Field HL
AUTHOR: D A Snyderman DA
AUTHOR: C Woods C
AUTHOR: R P Zager RP
AUTHOR: M Walker M
AFFILIATION: Department of Psychiatry, Jefferson Medical College, Philadelphia, PA 19107-5004, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: General hospital psychiatry.
COUNTRY: UNITED STATES
TITLE: Treating the patient who is disfigured by head and neck cancer.
PUBDATE: 19951101
A 46-year-old man with laryngeal carcinoma was admitted to the medical service for lethargy. The medical team requested a psychiatric consultation to assist with the patient's depression, substance abuse, and noncompliance. The case is presented and discussed with reference to the issues of depression, disfigurement, dysfunction, and substance abuse in the patient with head and neck cancer.


13. DOCID:26843 SCORE: 0.00262554986202171
DOCNO: 11057328
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Taxoids
QUALIFIER: drug therapy
QUALIFIER: pharmacology
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: K Daido K
AUTHOR: K Arita K
AUTHOR: N Ohashi N
AUTHOR: K Nakamura K
AFFILIATION: Dept. of Respiratory Disease, Hiroshima Red Cross Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of docetaxel-resistant lung cancer effectively treated with chemotherapy of gemcitabine and vinorelbine]
PUBDATE: 20001001
We report a NSCLC patient effectively treated with anti-cancer agents on an outpatient basis despite chemotherapy with carboplatin and docetaxel, he relapsed after achieving a transient response. Combination chemotherapy with gemcitabine and vinorelbine administered every three weeks in an outpatient clinic caused the lung cancer volume to reduce remarkably. This regimen was well tolerated and suitable for outpatients. Its usefulness as a second line chemotherapy in the treatment of NSCLC should be investigated.


14. DOCID:19474 SCORE: 0.00261706900824343
DOCNO: 1470626
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: G Auclerc G
AUTHOR: M Weil M
AUTHOR: C Borel C
AUTHOR: D Khayat D
AFFILIATION: Service d'Oncologie médicale, Groupe hospitalier Pitié-Salpétrière, Paris.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Presse médicale (Paris, France : 1983)
COUNTRY: FRANCE
TITLE: [Treatment of primary cancer of the breast in elderly women. Role of hormone therapy]
PUBDATE: 19921001
About 40 percent of newly diagnosed breast cancers occur in women older than 65. Hormonotherapy plays an important role as adjuvant treatment of primary cancers in post-menopausal women because of their great hormone-dependence. The drug of choice is tamoxifen which is very well tolerated. Its beneficial effect appears to be related to the duration of administration. It also seems to be particularly promising in the initial treatment (neoadjuvant) of elderly women and potentially beneficial in the breast cancers said to be of good prognosis when the axillary nodes are not involved.