0. DOCID:23959 SCORE: 0.00315438316465281
DOCNO: 7600136
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Helicobacter pylori
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: S Eidt S
AUTHOR: M Stolte M
AFFILIATION: Institute of Pathology, University of Cologne, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of gastroenterology & hepatology.
COUNTRY: ENGLAND
TITLE: The significance of Helicobacter pylori in relation to gastric cancer and lymphoma.
PUBDATE: 19950401
The evidence linking Helicobacter pylori and non-cardia gastric adenocarcinoma is accumulating. Patterns of strain specificities and host factors that increase epithelial proliferation and have implications for mutagenic effects are evolving. The decision by the World Health Organization and the International Agency for Research on Cancer to classify H. pylori as a 'definite' carcinogen, however, represents a milestone in the association of H. pylori with gastric carcinogenesis. The importance of H. pylori in gastric lymphoma has been underscored by the finding that H. pylori eradication can induce complete regression in low-grade mucosa-associated lymphoid tissue lymphomas, at least in the early stages of development.


1. DOCID:20250 SCORE: 0.00278987709114149
DOCNO: 8862710
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Taxoids
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: J P Armand JP
AFFILIATION: Department of Medicine, Institut Gustave-Roussy, Villejuif, Paris, France.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Anti-cancer drugs.
COUNTRY: ENGLAND
TITLE: The clinical rationale for developing docetaxel (Taxotere).
PUBDATE: 19960801
Clinical empiricism has recognized resistant breast cancer as a privileged target for docetaxel (Taxotere). This worldwide registration will offer medical oncologists the opportunity to develop new indications for docetaxel. Pharmacokinetics, preclinical optimal combination and clinical practice will constitute the rationale for the future development of docetaxel.


2. DOCID:22643 SCORE: 0.00262309324165023
DOCNO: 8965365
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: K Sugino K
AUTHOR: K Ito K
AFFILIATION: Ito Hospital.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Thyroid microcarcinoma]
PUBDATE: 19960501
The term "early cancer of the thyroid" is not clearly defined. Recently, microcarcinoma of the thyroid, less than 10 mm, has been frequently detected and in Ito Hospital smaller papillary carcinoma has increased in these 10 years. As rate of microcarcinoma found in autopsy cases were reported 10-28.4% in Japan, all of thyroid microcarcinoma are not thought to be developed clinically. In our hospital, papillary microcarcinoma diagnosed preoperatively underwent lobectomy with modified neck dissection in principle. Lymph node metastases were found in 65% of patients with papillary microcarcinoma. Further studies and discussion concerned whether thyroid microcarcinoma should be treated and how it should be treated, is necessary.


3. DOCID:22465 SCORE: 0.00254923375704502
DOCNO: 9457985
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: therapy
AUTHOR: T Römer T
AFFILIATION: Department of Obstetrics and Gynecology, Ernst-Moritz-Arndt-University of Greifswald, Germany.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.
COUNTRY: IRELAND
TITLE: Successful treatment of recurrent uterine bleeding during tamoxifen therapy by endometrial ablation.
PUBDATE: 19950401
Recurrent bleeding occurred in a premenopausal breast cancer woman during tamoxifen therapy. This bleeding required three curettages. Atypical hyperplasia and carcinoma were excluded, and the patient was prepared for endometrial ablation with two GnRH agonist injections. An endometrial ablation using the roller ball technique was carried out without complications. Tamoxifen therapy was continued postoperatively. During 24 months' follow-up the patient experienced no bleeding and no endometrium was seen by sonography.


4. DOCID:23750 SCORE: 0.00246404586745631
DOCNO: 8608062
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: economics
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: J A Glaspy JA
AFFILIATION: Department of Medicine, UCLA School of Medicine, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Economic outcomes associated with the use of hematopoietic growth factors.
PUBDATE: 19951101
The myeloid growth factors G-CSF and GM-CSF have had an impact on the supportive care of cancer patients as well as on the strategies utilized in chemotherapy dose intensification. Therapy with these factors has not been associated with improvements in survival, and hence an examination of their effects on economic outcomes is central to rational decision making regarding their use. Erythropoietin therapy has been shown to decrease transfusion requirements in anemic cancer patients undergoing chemotherapy and to improve the quality of life in responding patients. The available data on the economic outcomes associated with the use of these three factors in oncology practice are reviewed.


5. DOCID:23944 SCORE: 0.00235665887606139
DOCNO: 8597089
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: pharmacology
AUTHOR: S Agrawal S
AUTHOR: P K Rustagi PK
AUTHOR: D R Shaw DR
AFFILIATION: Hybridon, Inc., Worcester, MA 01605, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Toxicology letters.
COUNTRY: NETHERLANDS
TITLE: Novel enzymatic and immunological responses to oligonucleotides.
PUBDATE: 19951201
Oligonucleotide phosphorothioates (PS-oligos) are being studied as antisense agents for viral infection and cancer. In preclinical studies, PS-oligos produced dose-dependent changes in heart rate and blood pressure and significantly reduced serum hemolytic complement, which could be avoided by slowing infusion rates. Here, in vitro PS-oligo treatment of either human, rhesus monkey or guinea pig serum reduced hemolytic complement and further inhibited in vitro coagulation when added to whole blood or citrated plasma. These effects were dependent upon both oligonucleotide dose and structure. Oligonucleotides having identical sequences but containing methylphosphonates (Chimeric), 2'-O-methyl ribonucleosides (Hybrid) or 3' hairpin loop (Self-stabilized) had altered effects on complement and coagulation in vitro.


6. DOCID:22466 SCORE: 0.00235393047821406
DOCNO: 10154406
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Clinical Trials
QUALIFIER: therapy
QUALIFIER: legislation & jurisprudence
QUALIFIER: economics
PUBTYPE: Journal Article
JOURNALTITLE: Federal register.
COUNTRY: UNITED STATES
TITLE: Cancer treatment clinical trials--DoD. Notice of demonstration project.
PUBDATE: 19960101
This notice is to advise interested parties of a demonstration project in which the DoD will expand a current demonstration for breast cancer treatment clinical trials to include all cancer treatment clinical trials under approved National Institutes of Health, National Cancer Institute (NCI) clinical trials. Participation in these clinical trials will improve accessing to promising cancer therapies for CHAMPUS eligible beneficiaries when their conditions meet protocol eligibility criteria. DoD financing of these procedures will assist in meeting clinical trial goals and arrival at conclusions regarding the safety and efficacy of emerging therapies in the treatment of cancer. This demonstration project is under the authority of 10 U.S.C. 1092.


7. DOCID:22787 SCORE: 0.00234613166505591
DOCNO: 9048863
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cystectomy
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: M A Ghoneim MA
AFFILIATION: Department of Urology, University of Mansoura, Egypt.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Orthotopic bladder substitution in women following cystectomy for bladder cancer.
PUBDATE: 19970201
The feasibility of orthotopic substitution of the bladder after cystectomy for cancer has been realized. One must be careful about two potential drawbacks that may appear. Cases must be selected carefully and followed up to ensure that the adoption of such a procedure does not increase the risk of local recurrences. In the long term, if overcontinence proves to be a problem among a significant proportion of such cases, the logic of and the need for orthotopic substitution are lost. One then has to reconsider that intermittent catheterization of a continent cutaneous stoma provides a better alternative.


8. DOCID:16767 SCORE: 0.00227080088635617
DOCNO: 1793396
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: F McDermott F
AFFILIATION: Monash University, Alfred Hospital, Prahran, Victoria.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Australian family physician.
COUNTRY: AUSTRALIA
TITLE: Risk factors in breast cancer.
PUBDATE: 19911001
Risk factors are identified in less than 25 per cent of women who develop invasive breast cancer. The risk factors include a family history of breast cancer in a first degree family relative, late menopause, nulliparity, a first full term pregnancy after the age of 35 years, increasing age, P2 and DY mammographic parenchymal patterns, increasing dosage of non contraceptive oestrogens, mammary dysplasia associated with epithelial proliferation, a previous invasive breast carcinoma and carcinoma in situ.


9. DOCID:22444 SCORE: 0.00225150028981825
DOCNO: 8970599
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: J M Jenrette JM
AFFILIATION: Department of Radiation Oncology, Medical University of South Carolina, Charleston 29425, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: Malignant melanoma: the role of radiation therapy revisited.
PUBDATE: 19961201
In a multidisciplinary approach to the treatment of malignant melanoma, the role of radiation therapy is often relegated to one of minor importance. There is a supporting body of scientific literature that shows a relative radioresistance of melanoma when compared with other malignancies. Others have disputed the notion of resistance and have recommended radiation in a number of clinical settings including not only palliation but also in the primary management of melanoma. This article reviews the current and historical literature to better define the current role of radiation in a multidisciplinary approach for cancer management.


10. DOCID:17833 SCORE: 0.00217931657843973
DOCNO: 2056566
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Kidney Transplantation
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: T J Kinahan TJ
AUTHOR: M G McLoughlin MG
AUTHOR: A D Manson AD
AFFILIATION: Department of Surgery (Urology), Vancouver General Hospital, British Columbia, Canada.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Radical prostatectomy for localized prostatic carcinoma in the renal transplant patient.
PUBDATE: 19910701
Three renal transplant patients had prostatic carcinoma after transurethral prostatectomy at 2 weeks, 2 months and 12 years following transplantation. One patient had stage A1 disease, while 2 had stage A2 prostatic carcinoma. All patients underwent radical retropubic prostatectomy and pelvic lymph node dissection. All patients had residual cancer in the radical prostatectomy specimen but none had nodal or capsular involvement. The surgical technique and rationale for management are discussed.


11. DOCID:21663 SCORE: 0.00214397819734103
DOCNO: 9340233
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: H P Bruch HP
AUTHOR: G Kolbert G
AFFILIATION: Chirurgische Klinik, Medizinischen Universität zu Lübeck.
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: GERMANY
TITLE: [Results of deep rectum resection and intersphincteric rectum excision]
PUBDATE: 19970701
Low resection and intersphincteric extirpation of rectal cancer in the distal third of the rectum has become an accepted sphincter-saving method. From December 1990 to December 1994, 42 patients (17 women and 25 men) with a mean age of 67.2 years had a low resection or extirpation of the rectum at our institution. Eighteen patients received a transanal sutured anastomosis, 24 a stapler anastomosis. We had a lethality rate of 2.5% and a anastomotic insufficiency rate of 14%.


12. DOCID:18727 SCORE: 0.00196881794429999
DOCNO: 1557848
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: pathology
QUALIFIER: ultrasonography
QUALIFIER: pathology
QUALIFIER: ultrasonography
AUTHOR: H Miyashita H
AUTHOR: P Troncoso P
AUTHOR: R J Babaian RJ
AFFILIATION: Department of Urology, University of Texas M.D. Anderson Cancer Center, Houston.
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: BCG-induced granulomatous prostatitis: a comparative ultrasound and pathologic study.
PUBDATE: 19920401
We analyzed the ultrasound findings and the information obtained from serial whole-mount cross-section histologic examination of the prostates from 6 patients with bacillus Calmette-Guérin (BCG)-induced granulomatous prostatitis. Similarities to prostate cancer included a hypoechoic pattern on ultrasound, multifocality, and a propensity for a peripheral zone location. BCG-induced granulomatous prostatitis cannot be distinguished from cancer by ultrasonography. We suggest performing an ultrasound examination prior to starting BCG immunotherapy as a baseline for future reference to aid in the clinical diagnosis of BCG-induced granulomatous prostatitis.


13. DOCID:21424 SCORE: 0.00195615375338738
DOCNO: 9424328
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: metabolism
AUTHOR: B Floriańczyk B
AUTHOR: K Pasternak K
AUTHOR: L Grzybowska L
AUTHOR: J Peszyński J
AFFILIATION: Katedry i Zakładu Chemii Fizjologicznej Akademii Medycznej w Lublinie.
PUBTYPE: Journal Article
JOURNALTITLE: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.
COUNTRY: POLAND
TITLE: [Activity of isocitrate dehydrogenase in breast cancer]
PUBDATE: 19970601
The activity of isocitrate dehydrogenase (ICDH) was studied in the tissue of breast cancer and in the blood serum of the women suffering from this neoplasm. The comparative material was the physiological tissue of mammae and blood serum of the healthy women. The activity of ICDH in neoplasm tissue was more higher than in physiological tissue. In the blood serum of ill patients activity of this enzyme was higher than in control serums too.


14. DOCID:23263 SCORE: 0.00194531199385892
DOCNO: 7557724
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: prevention & control
QUALIFIER: methods
AUTHOR: M Glajchen M
AUTHOR: D Blum D
AUTHOR: K Calder K
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Health & social work.
COUNTRY: UNITED STATES
TITLE: Cancer pain management and the role of social work: barriers and interventions.
PUBDATE: 19950801
Quality of life has become increasingly important in the management of cancer, because patients with the disease are surviving longer. Although effective therapies exist, more than half of all cancer patients suffer unrelieved pain during illness and treatment. Undertreated and unnecessary pain represents a failure of the multidisciplinary team, including the social worker, to respond appropriately to the needs of cancer patients. This article increases social workers' awareness of the prevalence of cancer-related pain, identifies the barriers that undermine effective pain relief, and develops a model for social work intervention. Skills such as communication, assessment, problem solving, and psychological support are explored in detail.