0. DOCID:13339 SCORE: 0.00385975722883819
DOCNO: 3696750
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusion Pumps
QUALIFIER: instrumentation
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: physiopathology
QUALIFIER: drug therapy
AUTHOR: F I Ahlgren FI
AUTHOR: M B Ahlgren MB
AFFILIATION: Department of Anaesthesiology, General Hospital, Malmö, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: Pain.
COUNTRY: NETHERLANDS
TITLE: Epidural administration of opiates by a new device.
PUBDATE: 19871201
Epidural administration of opiates as a long-term treatment of cancer pain, even for out-patients, is now well established. Most reports describe intermittent injections given several times a day, which may have technical and personal disadvantages. Continuous epidural infusion may be preferable. This report describes 16 patients who were treated with epidural opiates delivered by plastic infusion pumps. Pain relief was effective, the equipment was inexpensive and home treatment was easily accomplished.

1. DOCID:3649 SCORE: 0.00319464924258222
DOCNO: 163141
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
AUTHOR: H Grossman H
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The evaluation of abdominal masses in children with emphasis on noninvasive methods. A roentgenographic approach.
PUBDATE: 19750301
Intravenous urography with total body opacification, and tomography as required, often give the most information toward evaluating abdominal masses in children. Ultrasonography is a noninvasive procedure which defines normal structures and differentiates cystic and solid tumors. The combination of these studies gives sufficient information about renal tumors to plan for possible surgery. Arteriography is not necessary for the diagnosis of Wilms' tumor, nor its surgical or medical management. Pseudotumor of the kidney is due to focal cortical hyperplasia. It can be diagnosed by nephrotomography, renal arteriography or renal scanning. The latter method is most accurate and has the lowest morbidity. Aortography is advisable in the evaluation of a patient with pheochromocytoma in an attempt to locate multiple tumors. Determining the extent of abdominal neuroblastoma by angiography and lymphangiography does not appear to influence the mode of therapy, not the survival rate; therefore, invasive diagnostic procedures do not appear to be indicated in neuroblastoma. Angiography is necessary in the evaluation of liver cancer. If one lobe is determined to be free of disease, lobectomy is a possible cure. Splenic cysts and choledochal cysts can be diagnosed by noninvasive methods such as ultrasonography or radioisotope scanning. Arteriography and percutaneous opacification are not necessary to make these diagnoses.

2. DOCID:5317 SCORE: 0.00304643277021827
DOCNO: 6174068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: B Windeyer B
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the Academy of Medicine, Singapore.
COUNTRY: SINGAPORE
TITLE: Therapeutic radiology -- a review.
PUBDATE: 19810701
Radiotherapy has played an important role in the curative and palliative treatment of cancer and should continue to do so in the future. As the radiotherapist is concerned with the overall management of the cancer patient, he should be a well trained clinician. Notable advances and improvements in apparatus have taken place recently. Better treatment planning, new forms of after loading techniques, neutron therapy, hyperthermia and other interesting developments are also discussed. With these advances, problems of radiological protection are reviewed and recommendations made from time to time by the International Commission and Radiological Protection to ensure the safety of both staff and patients.

3. DOCID:1939 SCORE: 0.00269856415583485
DOCNO: 324083
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
AUTHOR: D Zoedler D
AUTHOR: G Limbacher G
PUBTYPE: Journal Article
JOURNALTITLE: Der Urologe. Ausg. A.
COUNTRY: GERMANY, WEST
TITLE: [Report of 100 total prostatectomies (author's transl)]
PUBDATE: 19770301
A total retropubic prostatectomy is an exact, clearly defined operation, which, in our hands, has been extensively standardized: it lasts an average of 1 1/2 h, results in relatively little blood loss-in only 20% of the cases is one or more units of whole blood utilized-and is accompanied by complications that are kept within tolerable boundaries. Complete enuresis can be avoided by using a particular stitching technique for the outlet of the bladder. A considerable incontinence occurred in only one patient, who during the day was temporarily forced to wear a Cunningham clamp. In the postoperative stationary phase, mortality was 2%. A radical prostatectomy makes complete recovery from cancer of the prostate possible without mutilation and without aggravating functional injuries. It has, therefore, a secure place in the surgical therapy of cancer.

4. DOCID:1530 SCORE: 0.00250684166046271
DOCNO: 1115531
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Carcinogens
QUALIFIER: toxicity
QUALIFIER: chemically induced
AUTHOR: M Kuschner M
AUTHOR: S Laskin S
AUTHOR: R T Drew RT
AUTHOR: V Cappiello V
AUTHOR: N Nelson N
PUBTYPE: Journal Article
JOURNALTITLE: Archives of environmental health.
COUNTRY: UNITED STATES
TITLE: Inhalation carcinogenicity of alpha halo ethers. III. Lifetime and limited period inhalation studies with bis(chloromethyl)ether at 0.1 ppm.
PUBDATE: 19750201
Rats and hamsters were exposed to 0.1 ppm bis(chloromethyl)ether (BCME) six hours per day, five days per week throughout their lifetime. Additional groups of rats were given 10, 20, 40, 60, 80, and 100 exposures to 0.1 ppm BCME and then held until death. Forty cancers originating in the respiratory tract were found in the 200 rats involved in these studies. These included 14 cancers of the lung and 26 cancers of the nasal cavity. They occurred in dose-related fashion. A single undifferentiated carcinoma of the lung was seen in a hamster.

5. DOCID:3059 SCORE: 0.00233751763323494
DOCNO: 922013
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Daunorubicin
AUTHOR: S Neidle S
AUTHOR: G Taylor G
PUBTYPE: Journal Article
JOURNALTITLE: Biochimica et biophysica acta.
COUNTRY: NETHERLANDS
TITLE: Nucleic acid binding drugs. Part IV. The crystal structure of the anti-cancer agent daunomycin.
PUBDATE: 19771201
The crystal structure has been determined of the anti-cancer drug daunomycin, as the hydrochloride monohydrate pyridine salt. The overall structure, previously determined by X-ray analysis of an N-bromoacetyl derivative (Anguili, R., Foresti, E., Riva Di Sanserverino, L., Isaacs, N.W., Kennard, O., Motherwell, W.D.S., Wampler, D.L. and Arcamone, F. (1971) Nat. New Biol. 234, 78-80) has been confirmed, although substantial conformational differences are observed. The conformation described here is very similar to that found for the related drug carminomycin I (Wani, M.C., Taylor, H.L., Wall, M.E., McPhaill, A.T. and Onan, K.D. (1975) J. Am. Chem. Soc. 97, 5955-5956; Pettit, G.R., Einck, J.J., Herald, C.L., Ode, R.H. Von Dreele, R.B., Brown, P., Brazhnikova, M.G. and Gause, G.F. (1975) J. Am. Chem. Soc. 97, 7387-7388); it is suggested that this represents a significantly stable molecular conformation; an intramolecular C(7)...O(9) hydrogen bond is invoked to account for this. This conformation is likely to be at least close to that of daunomycin when bound to DNA.

6. DOCID:11792 SCORE: 0.00221604183864544
DOCNO: 6296209
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cattle Diseases
DESCRIPTOR: Dairying
QUALIFIER: veterinary
AUTHOR: J M Miller JM
AUTHOR: M J van der Maaten MJ
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of dairy science.
COUNTRY: UNITED STATES
TITLE: Bovine leukosis--its importance to the dairy industry in the United States.
PUBDATE: 19821101
Bovine leukosis describes lymphatic cancers of cattle. The most common form of this disease occurs in adult animals and is caused by bovine leukemia virus. Infection is widespread in the United States, especially in dairy cattle, but the virus produces tumors in only a small percentage of infected animals. Nevertheless, bovine leukemia virus has been receiving attention from the dairy industry because of its importance in health certification of cattle or semen intended for export. Another source of concern is whether bovine leukemia virus poses any risk to human health. These problems are discussed in the light of recent technological advances in tumor virus research and specifically regarding our current understanding of the biology of bovine leukemia virus.

7. DOCID:14851 SCORE: 0.00217991548576616
DOCNO: 2464914
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: J Y Kuo JY
AUTHOR: Y Nishio Y
AUTHOR: Y Okada Y
AUTHOR: H Takeuchi H
AUTHOR: O Yoshida O
AFFILIATION: Department of Urology, Faculty of Medicine, Kyoto University.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Hinyokika kiyo. Acta urologica Japonica.
COUNTRY: JAPAN
TITLE: [Complete remission of stage III penile cancer by multidisciplinary treatment: report of a case]
PUBDATE: 19880601
A case of penile cancer with bilateral metastatic inguinal lymph nodes in a 68-year-old male is reported. We used combination chemotherapy with methotrexate, bleomycin, and cisplatin for 2 courses before ilioinguinal lymphadenectomy. The surgical specimen of ilioinguinal lymph nodes revealed no viable tumors. It is clear that this combination therapy was effective against metastatic penile cancer and the role of preoperative chemotherapy is becoming increasingly important in metastatic penile cancer. This chemotherapy and surgical approach deserves additional trial in patients with metastatic penile cancer.

8. DOCID:7340 SCORE: 0.00214642380533141
DOCNO: 580557
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: S Warren S
AUTHOR: C E Brown CE
PUBTYPE: Journal Article
JOURNALTITLE: Archives of pathology & laboratory medicine.
COUNTRY: UNITED STATES
TITLE: Mammary and other tumors as a response to radiation and multiple stresses.
PUBDATE: 19780501
Parabiosis of paired NEDH rats and subsequent irradiation of one produced multiple stresses, particularly altered hormonal milieu. Benign mammary tumors developed in 8.6% of the control pairs, 12.7% of the shielded partners, and 19.7% of the irradiated rats. Mammary cancers developed in 5% of control pairs, 14.2% of the shielded partners, and 11.9% of the irradiated rats. With increased amounts of prolactin, the rate was 50% in shielded partner, 10% in the irradiated rats. Mesenchymal sarcoma develop at the anastomosis in parabiont rats. Their incidence rate in single controls is 3.1%, in parabiont control pairs 12.5%, in pairs with one partner irradiated 16.6%, and with both irradiated 23.1%. The incidence rate in other parts was increased threefold over controls in the irradiated partners. Radiation appears to be the dominant factor in both mammary and anastomotic tumors.

9. DOCID:14800 SCORE: 0.00214458185529118
DOCNO: 3024829
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
QUALIFIER: therapeutic use
AUTHOR: G Giaccone G
AUTHOR: M Donadio M
AUTHOR: P Ferrati P
AUTHOR: G Bonardi G
AUTHOR: L Ciuffreda L
AUTHOR: M Bagatella M
AUTHOR: A Calciati A
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Teniposide in the treatment of non-small cell lung carcinoma.
PUBDATE: 19870101
Forty-two evaluable patients with advanced non-small cell lung cancer were treated with teniposide at doses ranging from 120 to 180 mg/m2 on Days 1, 3, and 5 every 3 weeks. Thirty-four patients had received no prior chemotherapy. Seven partial responses (16.6%) were obtained (21% in chemotherapy-unexposed patients). Marrow toxicity was the main side effect: life-threatening thrombocytopenia occurred in 9% of patients, and 54.5% experienced severe leukopenia. Teniposide, at the doses and schedule employed, has moderate activity in non-small cell lung cancer.

10. DOCID:6091 SCORE: 0.00212554707921186
DOCNO: 7226076
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: analysis
AUTHOR: B W Børjesson BW
AUTHOR: G A Sarfaty GA
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Estradiol receptors in subpopulations of breast cancer cells isolated from human primary tumors.
PUBDATE: 19810401
Cancer cells isolated from biopsy specimens from seven women with primary breast cancer were analyzed for estradiol receptors. The cells were separated into subpopulations using the techniques of velocity centrifugation, buoyant density centrifugation, and density gradient electrophoresis. It was found that only large breast cancer cells (with diameters between 10.1-18.5 micrometers) concentrate tritiated estradiol. The total population of cancer cells has diameters between 5.6-18.5 micrometers, and the proportion of large cancer cells from different tumors varies from 8-59% of the total population. It is suggested that clinical regression following endocrine ablation is related to the proportion of large cancer cells and to the concentration of estradiol receptors in these cells.

11. DOCID:15979 SCORE: 0.00209308775638509
DOCNO: 3551847
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: drug therapy
AUTHOR: H Furue H
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Late effects of cancer chemotherapy]
PUBDATE: 19870401
Patients with specific types of cancer have achieved substantial prolongation of survival after successful cancer chemotherapy. Furthermore, cancer chemotherapeutic agents are being widely used as immunosuppressive drugs in patients with benign conditions. Both of these patient populations are at risk for development of late complications of treatment. Though the late effects of chemotherapy are less well defined, they are insidious in onset and not manifested clinically until damage have become overt and irreversible. Many reports on the late effects of chemotherapy demonstrate the importance of assessing not only the therapeutic results of various treatment program but also of evaluating the long-term complications of therapy in order to maximize the benefit of the treatment. Thus, skillful and judicious application of chemotherapy produces a minimum of delayed consequences.

12. DOCID:6154 SCORE: 0.00209068522835917
DOCNO: 472833
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: etiology
AUTHOR: S Hanowell S
AUTHOR: D E Lees DE
AUTHOR: T MacNamara T
PUBTYPE: Journal Article
JOURNALTITLE: Southern medical journal.
COUNTRY: UNITED STATES
TITLE: Auriculotemporal syndrome after combined modality therapy for cancer.
PUBDATE: 19790901
Auriculotemporal syndrome frequently follows trauma to the auriculotemporal nerve, a branch of the mandibular nerve. Classic symptoms are gustatory sweating and hyperemia, with pain occurring in less than 10% of cases. We have treated six patients for a variant of auriculotemporal syndrome following combined modality therapy for head and neck cancers. Unique was the presence of pain and the absence of gustatory sweating in all cases. The combination of radical surgery, chemotherapy, and irradiation obscured the "textbook" presentation, leading to initial misdiagnosis. Long-term relief (one year) from this atypical presentation of auriculotemporal syndrome was afforded by a simple mandibular nerve block, a technic that is of no sustained therapeutic benefit in the classic cases.

13. DOCID:1962 SCORE: 0.00205074329258213
DOCNO: 576889
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: F S Greenspan FS
PUBTYPE: Journal Article
JOURNALTITLE: JAMA : the journal of the American Medical Association.
COUNTRY: UNITED STATES
TITLE: Radiation exposure and thyroid cancer.
PUBDATE: 19770501
There are abundant experimental and clinical data to associate radiation exposure and thyroid cancer. The incidence of thyroid cancer increases with increasing doses of thyroidal radiation from 6.5 rads to 1,500 rads, but higher doses tend to destroy the gland and are associated with hypothyroidism rather than cancer. The peak occurrence of thyroid tumors is between five and 30 years after exposure, but a person may develop thyroid tumors as long as 50 years after irradiation. Multiple thyroidal lesions or disorders, including adenomas, thyroditis, and hypothyroidism as well as malignant neoplasms, can occur after radiation exposure. It is imperative, therefore, to study carefully all patients with a history of radiation exposure to the gland and to observe them carefully for life. Suggestions are made for the management of thyroid disease in these patients.

14. DOCID:9297 SCORE: 0.00200140366804275
DOCNO: 7078194
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
QUALIFIER: mortality
AUTHOR: R P Ruggiero RP
AUTHOR: S Fischer S
PUBTYPE: Journal Article
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: UNITED STATES
TITLE: Gastric malignancy: ten year experience at a community teaching hospital.
PUBDATE: 19820601
A ten-year review of gastric malignancy was undertaken and several factors examined. The degree of organ involvement played a significant role in determination of survival. Surgical resection, either palliative or curative, was associated with a more favorable short-term survival and bypass alone appeared to add nothing to patient survival time. The general lack of symptoms in early gastric cancer appears to be a majority determinant of the advanced state of malignancy in these patients. Early screening may represent a partial solution to this dilemma.